The invention discloses a touch display panel and a display device. The touch display panel is provided with a display area and a non-display area. The touch display panel comprises a touch panel, a display panel, an isolating layer and a plurality of pressure sensing units. The display panel comprises an array substrate, a first electrode, a pixel defining layer, a light emitting layer and a second electrode; the isolating layer is arranged between the touch panel and the second electrode; the pressure sensing units are arranged in the non-display area and each comprise a first resistor, a second resistor, a third resistor and a fourth resistor which form a Wheatstone bridge, wherein the first resistor and the third resistor are both used for sensing deformation in a second direction andarranged on the side, away from the touch panel, of the isolating layer, the second resistor and the fourth resistor are both used for sensing deformation in a third direction and arranged on the side, away from the display panel, of the isolating layer, and the second direction and the third direction intersect with each other and are both perpendicular to a first direction. By arranging the isolating layer, the detection performance of the pressure sensing units for user's press operation is improved, and the user experience is improved.