The invention discloses health-care vinegar which is prepared from the following preferable raw materials of barbary wolfberry fruits, honeysuckle flowers, dates, momordica grosvenori, ginger, hawthorns, licorice roots, mint and red-rooted salvia roots by the following steps of: pulverizing; adding water to soak; decocting; filtering decocted liquid; adding table vinegar to the liquid with a total weight part; fermenting; adding white sugar and a food additive; and sterilizing at high temperature, wherein the table vinegar is rice vinegar produced by the enterprise or Zhenjiang spiced vinegar (mature vinegar), and the food additive is potassium sorbate. The health-care vinegar is convenient to prepare and has the health-care effects of improving the immune competence, sterilizing, diminishing inflammation, digesting, reducing the blood pressure and the blood sugar, preventing coronary heart diseases and diabetes, and the like.