The invention relates to a 220 kV gas insulation transformer, and belongs to the technical field of transformers. According to the technical scheme, the 220 kV gas insulation transformer comprises a box, SF6 gas, an SF6 gas sleeve, a cable box, a transformer body, a transformer on-load voltage regulation switch, a gas density gauge, a pressure monitoring device, a sudden pressure relay, a gas temperature gauge, a winding temperature gauge, a plate radiator, a gas circulation pump, an airflow indicator, a blowing device and a cooling system intelligent control box, wherein the SF6 gas, the SF6 gas sleeve and the cable box are used for outgoing of a 220 kV high-voltage cable, the transformer body comprises an iron core, a coil and a lead, the gas density gauge, the pressure monitoring device, the sudden pressure relay, the gas temperature gauge and the winding temperature gauge are used for secondary protection, the plate radiator, the gas circulation pump, the airflow indicator, the blowing device and the cooling system intelligent control box are used for cooling the transformer, and an internal insulating and cooling medium of the transformer is the SF6 gas. Compared with a traditional oil-immersed transformer, the 220 kV gas insulation transformer has higher fire resistance, explosion resistance and safety and more complete monitoring and protection configuration, thereby being more suitable for being used in population concentration places such as city centers.