59 results about "Lupeol" patented technology

Methods of treating a fungal or yeast infection and of killing or inhibiting fungi or yeast are disclosed. The methods use derivatives of triterpenes that are abundant in birch bark and other plants. The triterpenes include betulin, allobetulin, and lupeol.

The invention provides improved processes for the extraction of betulin, lupeol, betulinic acid, suberinic acids, and/or other organic compounds and compositions from birch bark. In some embodiments, the birch bark can be physically processed prior to the extraction process, which can further improve the yield of the extraction. The bark processing can include, but is not limited to, one or more of pelletizing the bark, baling the bark, pucking the bark, or compressing the bark, to a form that is more dense per volume unit than prior to the processing.

The invention discloses a method to distill lupeol from birch genus plant that includes the following steps: smashing the dry birch bark, using methylene chloride to take back flowing and distilling, recycling methylene chloride, placing for deposition, filtering, removing filtrate and the washing deposit by a little cyclohexane several time to remove the low polarity impurity; recrystallizing for three times by absolute ethyl alcohol and acetone, the lupeol would be gained. The invention has the advantage of low cost, common raw material, simple technology.

The present invention provides birch bark pellets that include outer birch bark. The present invention also provides methods of manufacturing birch bark pellets from outer birch bark. The present invention also provides methods for obtaining a natural product from birch bark pellets. The birch bark pellets are manufactured from outer birch bark that includes relatively low amounts of inner birch bark and wood. The birch bark pellets meet the requirement for extraction, to obtain e.g., betulin and/or lupeol from the pellets.

The invention relates to a botanical acaricides applied to preventing mites on industrial crops such as fruit trees, vegetables and the like as well as a preparation method and new application thereof. The botanical acaricides is prepared from lupeol adding with surfactant, emulsifier, penetrant, synergist and the like, and has the characteristics of high efficiency, low toxicity, low residue, environment friendliness and the like.

An automobile lubricating oil additive is composed of the following raw materials in parts by weight: 3 to 6 parts of phosphorodithioate, 2 to 4 parts of random polypropylene, 1.2 to 3 parts of oligomer of trimethyl hydrogen quinazoline, 4 to 6 parts of phenothiazine, 5 to 8 parts of phenyl-2-naphthylamine, 2 to 4 parts of methyl silicone oil, 3 to 5 parts of calcium oxide, 1 to 2 parts of succinate, 4 to 7 parts of mesembryanthemoidigenic acid, 3 to 6 parts of glycerin acrylate, 7 to 10 parts of lupeol palmitate, 5 to 8 parts of linolenic acid, 6 to 9 parts of coconut diethanolamide, 5 to 8 parts of inositol hexaphosphate, 2 to 4 parts of calcium chloride, 6 to 10 parts of polyacrylic acid, 4 to 7 parts of sodium dodecyl benzene sulfonate, 2 to 6 parts of tetrahydropalmatine, 3 to 5 parts of lupeol palmitate, 8 to 16 parts of benzyl alcohol, and 7 to 12 parts of sulfurized calcium alkyl phenate. The provided automobile lubricating oil additive has an improved viscosity index and a good lubricating performance, can effectively prevent lubricating oil from being oxidized or degraded, and prolongs the service life of lubricating oil.

The invention discloses lubricating paste special for bearings. The lubricating paste is prepared from butter, phosphite ester, talcum powder, aluminum disulfide, paraffin base, naphthenic oil, succinimide succinate, cross-linked polyvinylpolypyrrolidone, aerosil, boron nitride, glycerin, poly-succinimide, graphite, amino-thioester, phosphoric acid, p-hydroxybenzaldehyde, citrate methyl ester, citric acid mono-methyl ester iso-dehydrocostus lactone and lupeol palitate. Compared with the prior art, the lubricating paste is prepared from various elements through a special process and used for the lubrication of the bearings, is less volatile, resistant to high temperature and good in lubrication effect, and has popularization and application value.

The invention discloses a preparation for preventing and controlling root rot of Wen codonopsis pilosula and a preparation method of the preparation, and belongs to the technical field of pesticides.The preparation for preventing and controlling the root rot of the Wen codonopsis pilosula is composed of the following raw materials: aspergillus niger powder, alfalfa powder, chlorella extract, pinecone shells, urea, lobelia chinensis extract, rhizoma cimicifugae, sinapyl alcohol, gallic acid, 4-hydroxy-benzoic acid and lupeol. Before the Wen codonopsis pilosula is cultivated, the preparation and seeds are mixed, the prevention effect on the root rot of the Wen codonopsis pilosula is 97.3% to 98.2%, the cold resistance is 92.9% to 94.7%, the per mu yield is 310-317 kg/mu and is increased by29.2% to 32.1% than that of conventional planting, and the preparation has no pesticide residues and has significant economic benefits.

The invention relates to a pharmaceutical composition, characterized in that it comprises, as an active substance, a combination of beta-elemene, lupeol and a pharmaceutically active agent selected from cinnamaldehyde, 2-hydroxycinnamaldehyde, 2'- benzoyloxycinnamaldehyde, beta-sitosterol, curcumin and the mixtures thereof.

The invention discloses a lubricating oil which is prepared from the following raw materials in parts by weight: 5-15 parts of high-base-number calcium sulfonate, 3-6 parts of zinc dialkyl dithiophosphate, 2-5 parts of p-hydroxyphenylmethyl aldehyde, 1-4 parts of methyl citrate, 4-6 parts of salicylate, 1-4 parts of monomethyl citrate, 2-6 parts of tetrahydropalmatine, 3-5 parts of mesembryanthemoidigenic acid, 5-10 parts of succinate, 3-8 parts of isodehydrocostus lactone, 4-7 parts of lupeol palmitate and 4-9 parts of alkylated diphenylamine. The lubricating oil has the advantages of favorable adhesion property and excellent corrosion resistance, can absorb abundant heat under high-temperature conditions, and can effectively prevent water and vapor from influencing the apparatuses.

The invention relates to a track lubricating grease which is prepared from the following raw materials in parts by weight: 3-9 parts of isocetanol palmitate, 1.5-6 parts of lanolin alcohol polyether, 3-6 parts of methyl citrate, 4-8 parts of monomethyl citrate, 3-5 parts of lupeol palmitate, 1-3 parts of antioxidant, 4-6 parts of dioxane, 1.5-4 parts of hypnone, 3.2-7 parts of sodium citrate, 5-9 parts of polyalkylene ethylene glycol, 2-4 parts of vulcanized alkane, 3-8 parts of 4-methyl-1-pentene and 1.2-4 parts of trichloromethane. The lubricating grease can form a lubricating layer between the track and object to reduce the friction between the track and object and prolong the service life of the track, and has certain cooling actions.

The invention discloses a lupeol pyridine quaternary ammonium salt derivative, a preparation method and application thereof, belongs to the field of drug synthesis, and provides a lupeol pyridine quaternary ammonium salt derivative and application in treatment and/or prevention of cancer, wherein the molecular formula of the lupeol pyridine quaternary ammonium salt derivative is C38H59IN2O2, and the molecular weight of the lupeol pyridine quaternary ammonium salt derivative is 702.1. According to the invention, a water-soluble lupeol pyridine quaternary ammonium salt derivative is synthesizedby using lupeol as an initial raw material, and pharmacological experiments prove that the derivative has a remarkable inhibition effect on various tumor cell strains, has an obvious anti-cancer effect compared with lupeol, has a low toxic effect on normal cell strains, is good in hydrophilicity, is easily dissolved in solvents such as water, ethanol, DMSO and the like, and has solubility superiorto that of lupeol, so that the derivative has great research and development potential; and the lupeol pyridine quaternary ammonium salt derivative is expected to be developed into an anti-tumor drugand has certain medical value and market prospect.

The invention discloses a lupeol derivative as well as a synthesis method and application thereof, and relates to the technical field of biosynthesis. According to the synthesis method, a new synthesis pathway is adopted, and CYP450 enzymes from different plant sources are used for modifying lupeol; and by expressing a gene for encoding lupeol synthetase, a gene for encoding CYP450 enzyme and a gene for encoding CPR reductase in exogenous microorganisms capable of generating 2, 3-squalene oxide, various novel lupeol derivatives can be obtained, and a foundation is laid for further development of the lupeol.

The invention relates to the technical field of traditional Chinese medicines and crude drugs, specifically to a Synsepalum dulcificum leaf extract and application of the same in preparation of drugs or health products used for treating diabetes or hyperlipidemia. The extract contains an effective component beta-Amyrin acetate and/or another effective component lupeol acetate. The extract exerts good effect on reducing blood sugar and increasing the content of insulin in blood and can be used as a drug or health product for treating diabetes; moreover, the effective components of the extract are definite, which is beneficial for controlling drug quality and medication safety.

The invention belongs to the field of building materials, and specifically relates to an antibacterial coating and a preparation method thereof. The antibacterial coating is prepared from the following main raw materials in parts by weight: lupeol, palmatine hydrochloride, coptisine, bergenin, citronellol, rutin, ursolic acid, nanometer Chlorite-schist powder, titanium dioxide, trimethylolpropane,hydrogenated castor oil and manganese acetate. According to the invention, the lupeol, the palmatine hydrochloride, the citronellol, the rutin and the ursolic acid with antibacterial effects are added into the antibacterial coating to improve antibacterial properties of the coating and reduce propagation of bacteria on the surface of the coating; and after the antibacterial coating is coated ontothe surface of a building which is in an environment with easy propagation of bacteria, the building is insusceptible to mildewing.

Disclosed is cleaning type internal combustion engine lubricating oil. The cleaning type internal combustion engine lubricating oil comprises, by weight, 6-14 parts of lupeol palmitate, 3-7 parts of antioxidant, 4-9 parts of monopotassium phosphate, 4-6 parts of bisphenol A polycarbonate, 3-5 parts of citric acid mono-methyl ester, 2-6 parts of dodecanedioic acid, 7-11 parts of epoxy acrylic acid, 20-30 parts of base oil, 1-4 parts of amino phosphate, 3-10 parts of sorbitan monooleate, 2-6 parts of glycerinum monooleate, 7-11 parts of dimethyl phthalate, 2-6 parts of walnut oil and 1-2 parts of nanometer hafnium carbide powder. The cleaning type internal combustion engine lubricating oil has the advantages that the cleaning performance is excellent, accumulated carbon can be excellently cleaned, and meanwhile, certain sealing effect is achieved.

The invention belongs to the research field of bioactive substance preparation processes, and provides a synthesis method of lupeol. The lupeol is prepared by reduction reaction in the presence of a reducer and strong alkaline by taking betulinaldehyde or a 3-ester derivative thereof as raw materials. The method is less in experimental steps, simple to operate and high in yield, and the production cost of the lupeol is remarkably reduced.

The invention belongs to the technical field of cosmetics and skin external preparations, and particularly discloses a microemulsion composition of oleanolic acid as well as a preparation method and application of the microemulsion composition. The microemulsion composition comprises oleanolic acid, a surfactant, a cosurfactant, plant essential oil, water, cyclodextrin and a water-soluble chitosan derivative, and further comprises solid lipid and/or preferable hair growth promoting substances (lupeol, isoimperatorin and icaritin), and other auxiliary materials or additives. The microemulsion composition can be self-emulsified to form a microemulsion or nano-emulsion in which the oleanolic acid is in a dissolved state and the content is relatively high, and can be further used for preparing a nano-structure lipid carrier. The microemulsion composition overcomes the defects that oleanolic acid is poor in solubility and not easy to absorb, meanwhile overcomes the defects that plant essential oil is unstable and insoluble in water, enhances effectiveness and stability, and is simple in preparation method, suitable for industrial production and wide in application prospect.