190results about How to "Good hypoglycemic" patented technology

The invention relates to a pharmaceutical composition having a blood sugar reducing effect. The pharmaceutical composition is prepared from the following raw materials: astragalus membranaceus, gorgon fruit, fructus rosae laevigatae, seed of Chinese dodder, burdock root, rhizoma anemarrhenae, yam, lalang grass rhizome, angelica, chrysanthemum, purslane, root of red-rooted salvia, radix ophiopogonis, ginseng, rhizoma atractylodis, folium mori, dendrobe, polished round-grained rice, medlar, root of Chinese trichosanthes, root of common peony, baked ginger, dogwood, raspberry, radix polygonati officinalis, myrrh, root of kudzu vine, ligusticum wallichii, prepared rehmannia root and fruit of Chinese magnoliavine. The pharmaceutical composition has high effective rate on diabetes and avoids relapse after curing; the pharmaceutical composition is simple in process, can low production cost and relieve economic burden of patients, and has a broad application prospect.

The present invention belongs to the field of bio-pharmaceuticals and diabetes, and discloses a polypetide and use of the polypetide in medicament preparation. The polypetide is (a) or (b): (a) polypeptide which is composed of amino acid sequence represented by SEQ ID NO:22; (b) polypetide which is composed of the amino acid sequence in (a) through replacement, deletion or adding one or several amino acids, has blood sugar reduction and / or blood fat reduction function and is derived from (a). The polypeptide and a plasmin inhibitor thereof have the following functions: reducing blood sugar, reducing triglyceride, total cholesterol or LDL in blood. The polypeptide can be used for preparing the blood sugar reduction medicament or blood fat reduction medicament, and particularly for the diabetes treatment medicament.

The invention relates to a method for preparing a sugarless clover and clover flower lyophilized powder tablet candy. The sugarless clover and clover flower lyophilized powder tablet candy comprises the following raw components in parts by weight: 5-80 parts of clover and clover flower lyophilized powder, 10-50 parts of xylitol, 1-60 parts of milk powder, 1-8 parts of vitamin C, 1-2 parts of calcium carbonate, 2-5 parts of hydroxymethyl propylcellulose and 0.1-0.3 part of magnesium stearate, and is prepared by the steps of material screening and weighing, soft material preparation, granulation, drying, particle conglomeration, press, and the like, and the method for preparing the candy is simple and easy. The lyophilized vegetable tablet candy has good functions of blood sugar reduction, decayed tooth and bleeding prevention and vitamin C, vitamin K, vitamin A and calcium supplementation, and the like, has convenient use, simple storage method and long quality guarantee period, is convenient for carrying, can effectively relieve and prevent diseases of diabetes mellitus, easy bleeding caused by vitamin K deficiency, and the like by being eaten frequently and sufficiently, and can be prepared simply and easily.

The invention discloses a food for improving hyperglycemia and hyperlipidemia of a diabetic patient and a preparation method thereof. The preparation method includes steps of mixing, drying and crushing red yeast rice powder, tartary buckwheat powder and mulberry fruit juice. The preparation method is simple. By means of lovastatin in the red yeast rice powder, total flavonoids in tartary buckwheat, 1-deoxynojirimycin in mulberry fruits and components such as various amino acids in a formula, blood glucose and blood fat can be inhibited or reduced. According to the formula, three raw materials are employed cooperatively so that a blood glucose reducing effect and a blood fat reducing effect can be improved. In addition, the mixture composed of the red yeast rice powder, the tartary buckwheat extract and the mulberry fruit juice provided in the invention can be used as a raw material. With addition of pharmaceutically acceptable auxiliary materials or components, the raw material can be prepared into tablets, capsules, granules, granular tea or the like. The food has a huge medicinal and health-caring value.

The invention provides a liraglutide variant and a preparation method thereof. An amino acid sequence of the liraglutide variant is X1-Ala-Glu-X2-Thr-Phe-X3-X4-Asp-Val-X5-X6-Tyr-Leu-X7-Gly-Gln-Ala-X8-Lys(N-epsilon-(N-alpha-Palmitoyl-L-gamma-glutamyl))-Glu-Phe-Ile-X9-Trp-X10-Val-Arg-Gly-Arg-X11, wherein X1 is His or Cys; X2 is Gly or Cys; X3 is Thr or Cys; X4 is Ser or Cys; X5 is Ser or Cys; X6 is Ser or Cys; X7 is Glu or Cys; X8 is Ala or is deleted; X9 is Ala or Cys; X10 is Leu, Cys or D-Ala; and X11 is Gly, Cys or Gly-Gly. The invention also provides a conjugate of the liraglutide variant and a preparation method thereof. The liraglutide variant and the conjugate thereof provided by the invention keep bioactivity of liraglutide; the half life is prolonged; and the burden of a patient is favorably relieved.

The invention relates to the technical field of Chinese herbal compounds, in particular to a composition mainly comprising synsepalum dulcificum leaves and application of the composition serving as a pharmaceutical product or a health product. The composition comprises the synsepalum dulcificum leaves, whole wheat grass, cyclocarya paliurus leaves and orange peel. The composition has the functions of lowering blood glucose and blood lipid, protecting the liver, slimming the body and the like and can serve as the health product or the pharmaceutical product.

The invention relates to a pharmaceutical composition for lowering blood sugar, which is prepared from the following raw materials according to a weight ratio: 20 of radix asparagi, 18 of radix scutellariae, 18 of cinnamon, 16 of angelica, 15 of rhizoma anemarrhenae, 12 of radix bardanae, 12 of licorice, 10 of astragalus mongholicus, 9 of atractylis ovata, 8 of radix paeoniae, 7 of prunus mume, 6of kudzu root, 6 of prepared rehmannia root, 4 of shizandra berry and 4 of ginseng. The pharmaceutical composition has a good curative effect, high clinical treatment effective rate, no recurrence after healing and a simple process, reduces the production cost and greatly alleviates the economic burden of the patients.

The invention discloses mulberry fruit vinegar and a preparation method thereof. The mulberry fruit vinegar is brewed from distilled water, mulberry fruits, mulberry roots, astragalus roots, roots of red-rooted salvia and 16 to 20-degree pure rice wine through acetic acid bacteria. The preparation method comprises the following steps of: steaming and airing the fresh mulberry fruits, adding the pure rice wine, grinding into paste, then adding the acetic acid bacteria, fermenting for 7 to 8 days at the room temperature being between 31 and 32 DEG C, and sterilizing with 100-110 DEG C steam after complete acidification; boiling the mulberry roots, the roots of red-rooted salvia and the astragalus roots by using the distilled water respectively, extracting the soup, and settling to obtain clear soup; and finally, mixing the sterilized mulberry fruit vinegar into the clear soup, settling, filtering, regulating the color and taste, settling and finally sterilizing The mulberry fruit vinegar is mellow in fruit aroma and good in mouthfeel, and has certain health-care effects of tonifying liver and kidneys, nourishing yin and tonifying blood, promoting the secretion of saliva or body fluid and moistening intestines and the like.

The invention provides a medicated food composition used for adjusting and assisting of blood glucose lowering. The raw materials comprise a blood glucose lowering composition, a conditioning composition and a detoxifying composition, specifically, 40-60 % of the blood glucose lowering composition, 30-50 % of the conditioning composition, and 1-20 % of the detoxifying composition, wherein the blood glucose lowering composition comprises fructus momordicae charantiae, folium mori, radix puerariae and L-arabinose, and the ratio of fructus momordicae charantiae to folium mori and radix puerariaeto L-arabinose is 2 to 2.2 to 1.1; the conditioning composition comprises fructus mori, radix astragali, radix ginseng, poria cocos and rhizoma polygonati, and the ratio of fructus mori to radix astragali, poria cocos and rhizoma polygonati to radix ginseng is 1 to 5 to 1.6; the detoxifying composition comprises corn stigma. The invention further provides a preparation method of the medicated foodcomposition. According to the medicated food composition, the ingredients are reasonably compounded, blood glucose is reduced in a synergistic manner, the efficacy of reducing blood glucose is improved, meanwhile, the effects of tonifying the liver and the kidney, replenishing blood, and tonifying Qi are achieved, the body is regulated from many aspects, the immunity is improved, and the cure rate for diabetes is improved to 98%.