Pharmaceutical composition for lowering blood sugar
A composition and blood sugar-lowering technology, applied in the field of biomedicine, can solve problems such as impaired insulin secretion, and achieve the effects of less recurrence, lower production costs, and a shorter course of treatment
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Embodiment 1
[0025] A pharmaceutical composition for lowering blood sugar, which is prepared from the following weight ratio raw materials:
[0026] Asparagus 20, Scutellaria 18, Cinnamon 18, Angelica 16, Anemarrhena 15, Burdock Root 12, Licorice 12, Astragalus 10, Atractylodes Macrocephala 9, White Peony 8, Wumei 7, Pueraria 6, Rehmanniae 6, Schisandra 4, Ginseng 4.
[0027] The preparation method of the above-mentioned pharmaceutical composition includes the following steps: take each weight of the above-mentioned raw material medicine for use; add 3 times the amount of water to decoct for 2 hours, filter and collect the filtrate, and concentrate the filtrate into an extract with a density of 1.1g / ml; 60°C After drying, the powder is crushed to 100 mesh, filled into capsules, and sterilized to prepare a capsule preparation.
[0028] Dosage form and usage: This prescription is a capsule dosage form, three times a day, half an hour before meals, 2 capsules each time, 0.5g each capsule, two weeks ...
Embodiment 2
[0030] Animal pathology experiment
[0031] Test animals: 50 Wistar rats, male, 180-200g. After the rats were adapted to feeding for 5 days in the animal room, 10 rats were randomly selected as the normal control group and fed with ordinary maintenance feed. High-sugar and high-fat feed formula: rat basic feed 68%, sucrose 10%, egg yolk powder 9%, lard 8%, cholesterol 1%, bile salt 0.2%.
[0032] Implementation mode: The remaining 40 were fed with high-sugar and high-fat feed for 4 weeks. After 4 weeks of fasting for 18 hours, the rats were given an intravenous injection of 20 mg / Kg of streptozotocin (STZ) once every two days. After two use, the model was successful if the blood glucose and blood lipids remained high. Thirty rats successfully modeled were selected and randomly divided into 3 groups, each with 10 rats, namely the model group (no drugs are administered), the drug group of Example 1 of the present invention, 10 mg / Kg, and the control drug group: Gliclazide administe...
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