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699 results about "Nanocapsules" patented technology
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A nanocapsule is a nanoscale shell made from a nontoxic polymer. They are vesicular systems made of a polymeric membrane which encapsulates an inner liquid core at the nanoscale. Nanocapsules have many uses, including promising medical applications for drug delivery, food enhancement, nutraceuticals, and for self-healing materials. The benefits of encapsulation methods are for protection of these substances to protect in the adverse environment, for controlled release, and for precision targeting. Nanocapsules can potentially be used as MRI-guided nanorobots or nanobots, although challenges remain.
Amphiphilic polymeric vesicles
InactiveUS6916488B1Ultrasonic/sonic/infrasonic diagnosticsPowder deliveryNanocapsulesCell Membrane Proteins
Vesicles made from amphiphilic copolymers are disclosed. The amphiphilic copolymers can be ABA copolymers, where one of A and B is hydrophilic and the other is hydrophobic. AB copolymers can also be used. The copolymers may be crosslinked to form nanocapsules. Crosslinking can be accomplished using a variety of methods, including end to end polymerization of copolymers having terminal unsaturated groups. Molecules, such as membrane proteins, can be incorporated into the wall of the vesicles or nanocapsules.
Owner:BIOCURE
Liposomal curcumin for treatment of cancer
The present invention provides a compositions and methods for the treatment of cancer, including pancreatic cancer, breast cancer and melanoma, in a human patient. The methods and compositions of the present invention employ curcumin or a curcumin analogue encapsulated in a colloidal drug delivery system, preferably a liposomal drug delivery system. Suitable colloidal drug delivery systems also include nanoparticles, nanocapsules, microparticles or block copolymer micelles. The colloidal drug delivery system encapsulating curcumin or a curcumin analogue is administered parenterally in a pharmaceutically acceptable carrier.
Owner:BOARD OF RGT THE UNIV OF TEXAS SYST
Carbon nanocapsule supported catalysts
ActiveUS6841509B1Improve developmentEasy to modifyNanotechSynthetic resin layered productsCatalytic metalCatalytic effect
A carbon nanocapsule supported catalysts. At least one kind of catalytic metal particle is deposited to a carbon nanocapsule, wherein the carbon nanocapsule has the following formula: F(−M)n, in which F is the carbon nanocapsule, M is the catalytic metal particle, and n is the number of the catalytic metal particle. By applying the carbon nanocapsule as a catalyst support, the catalytic behavior of the catalytic metal particle is specialized, the dispersion is improved, and the catalytic effect is enhanced.
Owner:IND TECH RES INST
Fragrance compositions
Owner:PROCTER & GAMBLE CO
Controlled release compositions of estradiol metabolites
The present invention provides improved sustained release formulations of estradiol metabolites, including 2-hydroxyestradiol, 2-methoxyestradiol, 4-hydroxyestradiol and 4-methoxyestradiol, useful for therapeutic treatments. The invention also provides methods of producing sustained release forms of estradiol metabolites. The compositions of the present invention include microparticles, nanoparticles, patches, crystals, gels, rods, stints, pallets, discs, lozenges, wafers, capsules, films, microcapsules nanocapsules, hydrogels, liposomes, implants and vaginal rings. Compositions also include formulations for transdermal and intravenous delivery of estradiol metabolites. The present invention provides numerous improvements over previous forms of estradiol metabolites, such advantages including the sustained release of normally short half-life compounds to maintain therapeutic blood levels.
Owner:PR PHARMA
Fragrance compositions
A composition comprising:(a) a fragrance oil comprising:(i) top note perfume raw material, or mixture of perfume raw materials, with a boiling point of less than, or equal to, about 250° C. at 1 atmosphere pressure;(ii) middle or base note perfume raw material, or mixture of perfume raw materials, with a boiling point of greater than 250° C. at 1 atmosphere pressure;(b) an entrapment material which is selected from the group consisting of polymers; capsules, microcapsules and nanocapsules; liposomes; pro-perfumes selected from more than 1 type of pro-chemistry; film formers; absorbents; cyclic oligosaccharides and mixtures thereof;(c) greater than 50% volatile solvent;wherein the weight ratio of the top note perfume raw materials to middle or base note perfume raw materials within the fragrance oil is in the range from about 1:20 to about 20:1.The present invention provides compositions wherein the light, fresh, fruity, citrus, green or delicate floral top note fragrance character remains detectable for greater than about 2 hours, preferably greater than about 4 hours, more preferably greater than about 6 hours, after the composition has been applied to the substrate.
Owner:PROCTER & GAMBLE CO
Liposomal curcumin for treatment of neurofibromatosis
The present invention provides a compositions and methods for the treatment of Neurofibromatosis Type 1 and 2, in a human patient. The methods and compositions of the present invention employ curcumin or a curcumin analogue encapsulated in a colloidal drug delivery system, preferably a liposomal drug delivery system to target Merlin and proteins of the Merlin pathway. Suitable colloidal drug delivery systems also include nanoparticles, nanocapsules, microparticles or block copolymer micelles. The colloidal drug delivery system encapsulating curcumin or a curcumin analogue is administered parenterally in a pharmaceutically acceptable carrier.
Owner:BOARD OF RGT THE UNIV OF TEXAS SYST
Fragrance compositions
Owner:PROCTER & GAMBLE CO
Stable nanocapsule systems for the administration of active molecules
The invention is aimed at nanocapsule systems characterized in that they have high stability during long periods of time. These systems are useful for the controlled release of pharmacologically or cosmetically active ingredients of highly lipophilic nature. The system comprises nanocapsules with an average size less than 1 μm dispersed in an aqueous medium, wherein the nanocapsules have a structure which comprises a lipophilic phase containing a phospholipid component and one or more saturated and / or unsaturated C12-C24 chain fatty acids or derivatives thereof; and a hydrophilic phase which comprises chitosan or a derivative thereof and a polyoxyalkylenated compound.
Owner:ADVANCELL ADVANCED IN VITRO CELL TECH
Liquid crystal display device and fabricating method thereof
ActiveUS20140184984A1Increase productionReduce processSemiconductor/solid-state device manufacturingNon-linear opticsNanocapsulesLiquid crystal molecule
Provided are a liquid crystal display (LCD) device and fabricating method thereof. The liquid crystal display device, including a liquid crystal panel, includes: a first substrate, including: a pixel electrode, and a common electrode separated from the pixel electrode, a ratio of a width of the pixel electrode to a distance between the pixel electrode and the common electrode being in a range of about 1:1 to 1:7, and a nanocapsule liquid crystal layer formed on the first substrate, the nanocapsule liquid crystal layer including: a buffer material, and nanocapsules, each filled with liquid crystal molecules.
Owner:LG DISPLAY CO LTD
Thermal interface material
InactiveUS6947285B2Improve thermal conductivitySemiconductor/solid-state device detailsSolid-state devicesHigh densityNanocapsules
A thermal interface material (40) includes a polymer matrix and a number of carbon nanocapsules incorporated in the polymer matrix. The thermal interface material is sandwiched between a heat source (30) having a high density and a heat sink (50). The thermal interface material can provide a maximum surface contact area and can increase thermal conductivity between the heat source and the heat sink.
Owner:HON HAI PRECISION IND CO LTD
Nanoparticle composites and nanocapsules for guest encapsulation and methods for synthesizing same
Nanoparticle composites and nanocapsules for guest encapsulation and methods for synthesizing same. One synthesis method includes providing a nanoparticle template; and forming a shell on the nanoparticle template by polymerizing a monomer on the nanoparticle template to form a nanoparticle composite defined by the shell and the nanoparticle template. Another synthesis method includes providing a nanoparticle template; forming a shell on the nanoparticle template by polymerizing a monomer on the nanoparticle template; and dissolving the nanoparticle template to thereby form a hollow nanocapsule defined by the shell. Another synthesis method includes providing a nanoparticle template carrying a guest molecule; and forming a shell on the nanoparticle template by polymerizing a monomer on the nanoparticle template to thereby encapsulate the guest molecule. This method can also include dissolving the nanoparticle template to form a nanocapsule defined by the capsule shell material, wherein the guest material resides in the nanocapsule.
Owner:NORTH CAROLINA STATE UNIV
Fragrance compositions
A composition comprising:(a) from about 0.01% to about 99%, by weight, of a fragrance oil, wherein the fragrance oil comprises about 5% or greater, by weight of fragrance oil, of a top note perfume raw material, or mixture of top note perfume raw materials, and wherein the top note perfume raw materials have a boiling point of less than, or equal to, about 250° C. at 1 atmosphere pressure;(b) an entrapment material which is selected from the group consisting of polymers; capsules, microcapsules and nanocapsules; liposomes; pro-perfumes selected from more than 1 type of pro-chemistry; film formers; absorbents; cyclic oligosaccharides and mixtures thereof;(c) greater than about 50% volatile solvent.The present invention provides compositions wherein the light, fresh, fruity, citrus, green or delicate floral top note fragrance character remains detectable for greater than about 2 hours, preferably greater than about 4 hours, more preferably greater than about 6 hours, after the composition has been applied to the substrate.
Owner:THE PROCTER & GAMBLE COMPANY
Fragrance compositions
The present invention relates to a composition comprising:(a) a fragrance oil wherein the fragrance oil comprises:(i) one or more perfume raw materials with a high odour impact which have an odour detection threshold of less than, or equal to about 50 parts per billion(ii) less than about 4%, by weight of the fragrance oil, of top note perfume raw materials where in the top note perfume raw materials have a boiling point of less than 250° C. at 1 atmosphere pressure(b) an entrapment material which is selected from the group consisting of polymers; capsules, microcapsules, and nanocapsules; liposomes; film formers; absorbents; cyclic oligosaccharides and mixtures thereof;wherein the perfume raw material and the entrapment material exist in an associated form on the substrate and wherein the weight ratio of high odour impact perfume raw materials which have an odour detection threshold of less than, or equal to, about 50 parts per billion to entrapment material within the associated form falls in the range of about 1:20 to about 20:1.
Owner:THE PROCTER & GAMBLE COMPANY
Vectorization of dsRNA by cationic particles and topical use
InactiveUS20070003609A1Special deliveryMicroencapsulation basedInorganic particleInorganic particles
The present invention relates to vectorization of double stranded RNA oligonucleotides by cationic particles chosen from among surfactant micelles, block or non-block polymer micelles, cationic liposomes and niosomes, cationic oleosomes and cationic nanoemulsions, as well as from among cationic organic or inorganic particles and nanocapsules, and topical compositions for the skin, mucous membranes or eyes.
Owner:LOREAL SA
Fragrance compositions
A composition comprising: (a) a fragrance oil wherein the fragrance oil comprises greater than 0.5% of a top note perfume raw material, or mixture of top note perfume raw materials, with a boiling point of less than, or equal to, 250° C. at 1 atmosphere pressure; (b) an entrapment material which is selected from the group consisting of polymers; capsules, microcapsules and nanocapsules; liposomes; film formers; absorbents; cyclic oligosaccharides and mixtures thereof; (c) greater than 50% volatile solvent; wherein the perfume raw material and the entrapment material exist in an associated form on the substrate and wherein the weight ratio of the top note perfume raw material to the entrapment material within the associated form is in the range from about 1:20 to about 20:1. The present invention provides compositions wherein the light, fresh, fruity, citrus, green or delicate floral top note fragrance character remains detectable for greater than about 2 hours, preferably greater than about 4 hours, more preferably greater than about 6 hours, after the composition has been applied to the substrate.
Owner:THE PROCTER & GAMBLE COMPANY
Amphiphilic ternary polymer brush and nano capsule
ActiveCN102911370AEasy to adjust and control the sizeThe particle size is easy to adjust and controllableMicroballoon preparationMicrocapsule preparationPolymer scienceSide chain
The invention discloses an amphiphilic ternary polymer brush and a nano capsule. The amphiphilic ternary polymer brush has the following general formula, wherein A is polymer main chain, B is lipophilic polymer side chain, C is photo-crosslinked polymer side chain, D is hydrophilic polymer side chain, and the side chains B, C and D are randomly grafted onto the main chain A; and the nano capsule is prepared through dispersing the amphiphilic ternary polymer brush into an oil-water two-phase system, and then performing light crosslinking reaction or reaction initiated by light. The amphiphilic ternary polymer brush solves the difficulty that the particle size of the capsule can not be adjusted and controlled effectively by using the conventional segmented copolymers, and the size of the prepared photo-crosslinked nano capsule is easily adjusted and controlled; the nano capsule prepared by the emulsion self-assembly method is simple in operation and easy to use in large-scale preparation; the prepared hollow nano capsule is large in casting quantity; the photo-crosslinked nano capsule provided by the invention is stable, and according to the light crosslinking method, nontoxicity and safety are reliazed, and the environmental protection is realized. The amphiphilic ternary polymer brush has the following general formula: A-g-(B-r-C-r-D).
Owner:GUANGZHOU CHEM CO LTD CHINESE ACADEMY OF SCI
Hollow core-shell nanometer mesoporous medicament carrying system with magnetism and luminescent performance, preparation method and application thereof
ActiveCN101966344AUniform particle sizeGood biocompatibilityInorganic non-active ingredientsNMR/MRI constrast preparationsThermal methodsBiocompatibility Testing
The invention discloses a hollow core-shell nanometer mesoporous medicament carrying system with magnetism and luminescent performance. In the medicament carrying system, a magnetic Fe3O4 hollow capsule is used as an inner core, mesoporous SiO2 is used as a shell layer, and an organic luminescent material and a biocompatible polymer are modified on the outer surface of the shell layer. A preparation method of the medicament carrying system comprises the following steps of: firstly, preparing monodisperse fusiform beta-FeOOH nanoparticles by a hydro-thermal method, coating mesoporous silicon dioxide on the surfaces of the nanoparticles, removing a pore-forming agent through thermal treatment, and simultaneously, converting the inner core into alpha-Fe2O3 from the beta-FeOOH, so that a cavity is generated in the inner core so as to form a hollow nanometer capsule structure; secondly, converting the inner core into the magnetic Fe3O4 hollow capsule through reduction treatment; and finally, modifying the organic luminescent material and the biocompatible polymer on the surface of the magnetic mesoporous nanometer capsule. The nanometer composite capsule of the invention has the advantages of core-shell structure and cavity structure, uniform particle size, high biocompatibility and excellent magnetism.
Owner:中国科学院上海硅酸盐研究所苏州研究院
High molecule bonding adriamycin medicine, nano capsule and preparation thereof
InactiveCN101234204AReduce manufacturing costPlay a role in isolationOrganic active ingredientsPharmaceutical non-active ingredientsPolymer scienceEnd-group
The invention provides a macromolecule bonding adriamycin medicine, a nanometer capsule and a preparation method thereof. The bonding medicine is bonded by a block copolymer of poly ethylene glycol-polylactic acid and adriamycin. Firstly, the block copolymer of poly ethylene glycol-polylactic acid is acquired by ring-opening polymerization of aliphatic cyclic esters with poly ethylene glycol, solvent and catalyst being in existence; then a carboxyl end group is transformed by a hydroxyl-terminated; and then with a condensing agent being in existence, the carboxyl end group carries out amidation reaction with the adriamycin; thus acquiring the macromolecule adriamycin bonding medicine. The bonding medicine has amphiphilic property, thus being able to self assembly to prepare the nanometer capsule with a core-shell structure in the water solution. The adriamycin is wrapped inside the capsule to play a role of isolation and protection, which overcomes the deficiencies of short circulation time in vivo, large dosage and severe allergic reaction existing in the current adriamycin preparation. In addition, the nanometer particles are expected to congregate in the blood circulation through the so-called 'enhanced infiltration and retention effect', so as to improve the targeting action of the adriamycin on the tumor location.
Owner:CHANGCHUN INST OF APPLIED CHEMISTRY - CHINESE ACAD OF SCI
Heat pipe operating fluid, heat pipe, and method for manufacturing the heat pipe
InactiveUS7213637B2Improve thermal conductivityGood capillary performanceMaterial nanotechnologyIndirect heat exchangersWorking fluidCarbon nanotube
A heat pipe (20) includes a pipe (21), a wick (22), and an operating fluid. The wick is a capillary structure including a carbon nanotube layer, and is fixed to an inside wall of the pipe. The operating fluid is sealed in the pipe and soaks into the wick. The operating fluid includes a pure liquid, and a plurality of nanometer-scale particles uniformly suspended in the pure liquid. The nanometer-scale particles can be carbon nanocapsules (30) or particles of a metal (32) with high thermal conductivity. Each carbon nanocapsule can further have a metal with high thermal conductivity filled therein. The carbon nanotube layer contains carbon nanotubes of small size and high thermal conductivity, therefore the capillary performance of the wick is good. Further, because the operating fluid includes nanometer-scale particles with high thermal conductivity, this ensures that the operating fluid has high thermal conductivity.
Owner:HON HAI PRECISION IND CO LTD
Thermal interface material
InactiveUS20040125565A1Desired ductility and strengthElasticitySemiconductor/solid-state device detailsSolid-state devicesHigh densityNanocapsules
A thermal interface material (40) includes a polymer matrix and a number of carbon nanocapsules incorporated in the polymer matrix. The thermal interface material is sandwiched between a heat source (30) having a high density and a heat sink (50). The thermal interface material can provide a maximum surface contact area and can increase thermal conductivity between the heat source and the heat sink.
Owner:HON HAI PRECISION IND CO LTD
Method of inhibiting restenosis using bisphosphonates
InactiveUS7008645B2Affect activityEfficient transportPowder deliveryBiocidePlatelet-Derived Growth Factor BetaParticulates
A method of inhibiting the activity or production of cytokines or growth factors associated with vascular restenosis, by administering to an individual an effective amount of an active ingredient comprising a bisphosphonate particle or a bisphosphonate particulate. The bisphosphonate may be encapsulated, embedded or adsorbed within the particle, dispersed uniformly in the polymer matrix, adsorbed on the particle surface, or in combination of any of these forms. The particles include liposomes or inert polymeric particles, such as microcapsules, nanocapsules, nanoparticles, nanospheres, or microparticles. The particulates include any suspended or dispersed form of the bisphosphonate which is not encapsulated, entrapped, or adsorbed within a polymeric particle. The particulates include suspended or dispersed colloids, aggregates, flocculates, insoluble salts and insoluble complexes of the active ingredient. The cytokines and growth factors include, but are not limited to interleukin 1-β, matrix metalloproteinase-2, and platelet-derived growth factor β (PDGFβ).
Owner:YISSUM RES DEV CO OF THE HEBREW UNIV OF JERUSALEM LTD
Fragrance compositions
Owner:HELTOVICS GABOR +3
Liquid crystal display including nanocapsule layer
InactiveUS20150109547A1Increase productionImprove response speedOptical light guidesNon-linear opticsNanocapsulesNormal state
Disclosed is a liquid crystal display device that may include a first substrate; a first electrode on the first substrate, the first electrode including a plurality of first inclined planes; a nanocapsule liquid crystal layer on the first electrode, the nanocapsule liquid crystal layer including a plurality of nano-sized capsules dispersed in a buffer layer, each of the plurality of nano-sized capsules including nematic liquid crystal molecules having a negative dielectric constant anisotropy; and a second electrode on the nanocapsule liquid crystal layer, the second electrode including a plurality of second inclined planes facing the plurality of first inclined planes, wherein the nanocapsule liquid crystal layer is substantially, optically isotropic in a normal state, and is optically anisotropic when a voltage is applied to the first and second electrodes.
Owner:LG DISPLAY CO LTD
Fragrance compositions
A composition comprising: (a) a fragrance oil comprising: (i) top note perfume raw material, or mixture of perfume raw materials, with a boiling point of less than, or equal to, about 250° C. at 1 atmosphere pressure; (ii) middle or base note perfume raw material, or mixture of perfume raw materials, with a boiling point of greater than 250° C. at 1 atmosphere pressure; (b) an entrapment material which is selected from the group consisting of polymers; capsules, microcapsules and nanocapsules; liposomes; pro-perfumes selected from more than 1 type of pro-chemistry; film formers; absorbents; cyclic oligosaccharides and mixtures thereof; (c) greater than 50% volatile solvent; wherein the weight ratio of the top note perfume raw materials to middle or base note perfume raw materials within the fragrance oil is in the range from about 1:20 to about 20:1. The present invention provides compositions wherein the light, fresh, fruity, citrus, green or delicate floral top note fragrance character remains detectable for greater than about 2 hours, preferably greater than about 4 hours, more preferably greater than about 6 hours, after the composition has been applied to the substrate.
Owner:THE PROCTER & GAMBLE COMPANY
Method of imaging lymphatic system using nanocapsule compositions
InactiveUS20050113697A1Ultrasonic/sonic/infrasonic diagnosticsEchographic/ultrasound-imaging preparationsSentinel lymph nodeRadiology
A composition is provided accompanying nonoparticles having diameters in the range of about 100 to 800 nanometers with hollow cores and outer shells with mechanical properties such that they rupture on exposure to predetermined ultrasound energy. The composition is useful for identifying sentinel lymph nodes.
Owner:HORIZON TECH FUNDING CO LLC
Polymerizable organosilicon nanocapsules
The present invention provides a polymerizable organosilicon nanocapsule, which includes: a nanoscale core A, which includes: at least one particle comprising at least one oxide or mixed oxide, KA-O, of at least one metal or semimetal selected from the group including main groups 2 to 6 of the Periodic Table, transition groups 1 to 8 of the Periodic Table, lanthanides, and mixtures thereof; and an organosilicon shell B, which includes: at least one organosilicon compound having the formula (Ia): (Si′O—)xSi—R (Ia) wherein R is a vinyl or allyl group; wherein x is a number from 0 to 20; wherein remaining free valences of Si are each independently (KA-O)—, SiO— or -Z; wherein remaining free valences of Si′ are each independently (KA-O)—, SiO—, -R, or -Z; wherein the Z's are each independently hydroxyl or alkoxy radicals; and wherein each Si and Si′ in the shell B have not more than one R group attatched thereto.
Owner:EVONIK DEGUSSA GMBH
Slow release fertilizer applicable to water-fertilizer integration and preparation method thereof
ActiveCN103910586ATo achieve the purpose of slow release and controlled releaseSuitable for integrationFertilizer mixturesPolymer dissolutionOrganic solvent
Owner:广西田阳县创新农业综合开发有限公司
Device for the production of capillary jets and micro-and nanometric particles
InactiveUS20050116070A1Eliminate the effects ofIncreasing drag effectFuel injection apparatusMachines/enginesNanoparticleMicrometer
The invention relates to a method and devices for the production of capillary microjets and microparticles that can have a size of between hundreds of micrometers and several nanometers. The inventive method makes use of the combined effects of electrohydrodynamic forces, fluid-dynamic forces and a specific geometry in order to produce micro- and nano-capsules or fluid jets, single- or multi-component, which, upon disintegrating or splitting, form a significantly monodispersed spray of drops which have a controlled micro- or nanometric size and which can also comprise a specific internal structure, such as, for example, a nucleus which is surrounded by a cortex of a different substance or several concentric or non-concentric nuclei or vesicles which are surrounded by a cortex.
Owner:UNIV DE SEVILLA
Microcapsule powder
A process for making hydrophobicized powders of micro- and / or nanocapsules involving the steps of: (a) providing an aqueous polymer solution containing at least one active ingredient and at least one hydrophilic polymer; (b) providing an oil component heated to a temperature above a gel point of the aqueous polymer solution; (c) dispersing (a) in (b) in the presence of a water-in-oil emulsifier to form a dispersion; (d) cooling the dispersion to a temperature below the gel point of the aqueous polymer solution to form micro- and / or nanocapsules containing the active ingredient encapsulated therein; (e) harvesting the micro- and / or nanocapsules from the dispersion; and (f) contacting the micro- and / or nanocapsules with an oil-absorbing auxiliary ingredient.
Owner:COGNIS FRANCE SA
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