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73 results about "Laryngeal Cancers" patented technology

Radiotherapy-targeted sensitizer and application thereof

The invention discloses a radiotherapy-targeted sensitizer, comprising the following seven miRNAs: an hsa-miR-138-2-3p stimulant, an hsa-miR-208b-3p stimulant, an hsa-miR-197-3p inhibitor, an hsa-miR-20b-3p inhibitor, an hsa-let-7a-5p inhibitor, an hsa-miR-16-1-3p inhibitor and an hsa-miR-21-5p inhibitor. The invention provides a novel radiotherapy-targeted sensitizer, which is capable of enhancing the radiosensitivity and is small in toxic and side effects, is especially applied to laryngeal cancer patients at various stages, and has an important application prospect. The novel radiotherapy-targeted sensitizer disclosed by the invention is expected to play a great role in improvement of the radiosensitivity and further increase of the curative effect, and good economic and social benefits are generated.
Owner:HANGZHOU NORMAL UNIVERSITY

Photosensitizers and MRI enhancers

The present invention relates to the use of a compound of formula 3 or a salt thereof for preparing a medicament or a phototherapeutic agent for the treatment of the following diseases, including: acne; AIDS; viral hepatitis; diabetic retinopathy; atypical pneumonia virus infection; coronary Arterial stenosis; carotid artery stenosis; intermittent claudication; Asian (chicken) avian influenza virus infection; cervical dysplasia or various cancers including: blood cancer, cervical cancer, nasopharyngeal cancer, tracheal cancer, laryngeal cancer, bronchial cancer , bronchiolar cancer, bladder cancer, esophagus cancer, stomach cancer, rectal cancer, colon cancer, prostate cancer, hollow organ cancer, bile duct cancer, urinary duct cancer, kidney cancer, uterine cancer, vaginal cancer and other gynecological adnexal cancers. The present invention also relates to methods of treating the above diseases. The present invention further relates to the use of a compound of formula 3 or a salt thereof for the preparation of a photodiagnostic agent for the detection of the above-mentioned diseases and diseases including: atherosclerosis, multiple sclerosis, diabetes, arthritis, rheumatism Arthritis, fungal infection, viral infection, chlamydia infection, bacterial infection, or parasitic infection, HIV infection, hepatitis, herpes simplex, shingles, psoriasis, cardiovascular disease and skin disease. The present invention also relates to methods of detecting the above diseases using photodiagnostic agents. The present invention further relates to a method of cryogenically sterilizing a surgical device or other device, comprising the steps of: providing a compound of formula 3 or a salt thereof on the device; subjecting the device to radiation treatment or sonication. The present invention further relates to a compound of formula 3 or a salt thereof linked or attached to a magnetic element. This compound acts as an MRI enhancer. The present invention also relates to the use of such MRI enhancers for performing MRI scans.
Owner:PHOTO DIAGNOSTIC DEVICES PDD

Biomarkers of Oral, Pharyngeal and Laryngeal Cancers

Provided herein are methods for detecting a head and neck cancer of the oral cavity or throat, optionally oral squamous cell carcinoma, comprising executing the step of determining the expression of two or more miRNA in a biological sample obtained from a subject, wherein the two or more miRNA are selected from the group consisting of hsa-let-7a, hsa-miR-16, hsa-miR-21, hsa-miR-451, hsa-miR-486-5p and hsa-miR-92a-3p, and wherein the level of expression of said two or more miRNAs in the biological sample relative to the level of expression of said two or more miRNAs in one or more cancer-free reference samples is indicative of the presence of a head and neck cancer of the oral cavity or throat of the subject.
Owner:UNIV OF TECH SYDNEY

Application of sophora tonkinensis gapnep lupanol

The invention discloses application of sophora tonkinensis gapnep lupanol, and particularly discloses application of the sophora tonkinensis gapnep lupanol to preparation of medicinal preparations fortreating tumors. The sophora tonkinensis gapnep lupanol provided by the invention has very good antitumor activity, can significantly inhibit growth of nasopharyngeal cancer cells, cervical cancer cells, esophageal cancer cells, liver cancer cells, laryngeal cancer cells, breast cancer cells and prostate cancer cells and inhibit metastasis of the nasopharyngeal cancer cells, and has a good application prospect in development into medicines for treating nasopharyngeal cancer and other diseases.
Owner:GUANGXI BOTANICAL GARDEN OF MEDICINAL PLANTS

Method for determining and screening differential metabolites of laryngeal cancer serum based on inverted phase chromatography time-of-flying mass spectrum

ActiveCN106324173AOptimizing Ion Source ConditionsOptimizing ColumnsComponent separationMetaboliteMultivariate statistics
The invention relates to a method for determining and screening differential metabolites of laryngeal cancer serum based on an inverted phase chromatography time-of-flying mass spectrum. The method is characterized by comprising the steps of settling protein from serum by virtue of an organic solvent, namely methanol, carrying out centrifugation and vacuum centrifugal drying, redissolving the serum into 200 microliters of pure water, introducing the solution into an inverted phase chromatography time-of-flying mass spectrometer for determination, and carrying out peak alignment, correction and standardization, multivariate statistics analysis and spectrum library searching, so as to find differential metabolites in serums of laryngeal cancer volunteers and healthy volunteers. The method is a brand-new method for identifying the differential metabolites in the serum, and the variation conditions of the serum metabolites of laryngeal cancer patients can be reflected by the differential metabolites, so that the method will contribute to the diagnosis, clinic treatment and prognosis of the laryngeal cancer and the research of pathogenesis of the laryngeal cancer.
Owner:CHINA NAT TOBACCO QUALITY SUPERVISION & TEST CENT +1

Traditional Chinese medicine preparation for main treatment of esophagus cancer and preparation method and application thereof

The invention provides a traditional Chinese medicine preparation and for main treatment of esophagus cancer and a preparation method thereof, and the traditional Chinese medicine preparation is prepared by selection of pearl, ginseng, calculus bovis, bear gall, borneol, stiff silkworm, house lizard, centipede, pseudo-ginseng, menthol, cinnabar, borax, smoked plum, propolis, tendril-leaved fritillary bulb, ephedra, pinellia tuber, scutellaria barbata and other medicinal materials. The traditional Chinese medicine preparation has the main effects of downbearing counterflow and checking vomiting, eliminating phlegm and detoxifying, softening hardness and dissipating stasis, transforming putridity and promoting tissue regeneration, dredging esophagus, relieving pain, and suppressing and resisting cancer. The traditional Chinese medicine preparation has good effects on esophageal discomfort, dysphagia, esophageal stenosis and obstruction caused by early and middle-late esophageal cancer, can kill cancer cells and inhibit the growth of the cancer cells, prevents the spread of the cancer cells, improves microcirculation, can be used for spasmolysis of smooth muscle so as to inhibit cancer cell growth and metastasis, is mainly used for esophageal cancer, also has certain curative effect on cardiac cancer, gastric cancer, ingluveosis phrenospasm, laryngeal cancer, lung cancer, liver cancer, breast cancer, pancreatic cancer, cervical cancer, intestinal cancer, esophagitis, various kinds of pharyngolaryngitis and the like.
Owner:刘洪 +1

A Chinese medicinal preparation for treating laryngeal carcinoma and its preparation method

The invention discloses a Chinese medicinal preparation for treating laryngeal cancer, including Ophiopogon japonicus, herba Dendrobii, american ginseng, trichosanthin, Solanum nigrum, Rabdosia rubescens, Snake berry, burdock root, rhizoma paridis, rhizoma paridis, a Chinese medicinal composition is prepare from fructus Lonicerae, herba Ecliptae, radix Angelicae sinensis, rhizoma Ligustici Chuanxiong, flos Cicadae, flos Rosae Rosae, fructus Trichosanthis, Bulbus Fritillariae Thunbergii, radix Curcumae, semen Persicae, notoginseng radix, Bombyx Batryticatus, flos Lonicerae, radix notoginseng, Scorpio, herba Scutellariae Barbatae, Coicis semen, carapax Trionycis, carapax et Plastrum Testudinis, and Glycyrrhrizae radix by soaking with water, decocting carapax et Plastrum A Chinese medicinal preparation for treating laryngeal cancer can effectively treat various common symptom caused by deficiency of lung and kidney yin, asthenia phlegm and upper phlegm, qi stagnation and blood stasis, stagnation in phlegm, deficiency of lung yin and qi and blood stagnation, and has certain curative effect on malignant tumors formed by ulcer type, nodule type, cauliflower type and mass type according to general morphological observation, and is safe and reliable.
Owner:陈海林

Chemotherapy-type anticancer drug inhalation powder preparation and preparing method and application thereof

The invention relates to a chemotherapy-type anticancer drug inhalation powder preparation and a preparing method and application thereof. According to the technical scheme, the chemotherapy-type anticancer drug inhalation powder preparation is obtained by mixing effective constituent powder with the grain diameter being 0.4-5 microns or 10-100 microns and carrier powder with the grain diameter being 10-100 microns. The effective constituent powder comprises a chemotherapy-type anticancer drug and Omega-3 fatty acid. The carrier powder comprises saccharides, an emulsifier and magnesium stearate. The application effect of the preparation in treatment of respiratory system cancers like a laryngeal cancer, a lung cancer and other tumor diseases is obvious. The inhalant form toxicity is small, the application is convenient, and the anticancer treatment effect has advantages compared with other dosage forms.
Owner:ZHOUSHAN SANHE BIOTECH CO LTD

Anti-cancer and cancer-preventing health-care medicated wine

InactiveCN108403962ASignificant effectInhibition of deterioration rateAnthropod material medical ingredientsAntineoplastic agentsEuroleonDisease
The invention provides anti-cancer and cancer-preventing health-care medicated wine. The anti-cancer and cancer-preventing health-care medicated wine is prepared from the following raw materials in parts by weight: 10 to 16 parts of glossy privet fruit, 13 to 17 parts of Chinese date, 12 to 18 parts of medulla tetrapanacis, 8 to 12 parts of asparagus, 2 to 4 parts of herba epimedii, 16 to 20 partsof radix celastri orbiculati, 14 to 18 parts of herba hedyotidis diffusae, 18 to 22 parts of lucid ganoderma, 3 to 5 parts of longan aril, 12 to 16 parts of herba cistanche, 15 to 17 parts of herba sculellariae barbatae, 4 to 8 parts of Chinese euroleon, 2 to 4 parts of smelly shell worm, 16 to 20 parts of herba rhodiolae, 2 to 6 parts of radix ginseng, 17 to 23 parts of manis pentadactyla, 11 to15 parts of sea horse and 100 to 160 parts of high-alcohol-content rice wine. The anti-cancer and cancer-preventing health-care medicated wine adopts pure natural plant materials, does not have any side effect, is reasonable to take, has remarkable curative effect on laryngeal cancer, breast cancer, rectal cancer, gastric cancer, liver cancer, bladder cancer, prostatic cancer, uterine cancer andthe like, effectively inhibits the deterioration speed of the disease state, alleviates symptoms, can effectively reduce surgical injury to patients subjected to surgery as well as radiotherapy and chemotherapy, and can improve the immune cell activity inhibited by radiotherapy and chemotherapy.
Owner:区少英

Antineoplastic pharmaceutical composition and application thereof

The invention provides a pharmaceutical composition and an application thereof, wherein the pharmaceutical composition consists of oridonin and cetuximab. The pharmaceutical composition, when used fortreating laryngeal cancer, shows an obvious synergistic effect. Based upon both in-vivo and in-vitro experiments, it is proved that the pharmaceutical composition provided by the invention can obviously inhibit the growth of laryngeal cancer cells, and the pharmaceutical composition is subjected to a mechanism of inhibiting the activation of an EGFR signaling pathway; and meanwhile, the pharmaceutical composition can promote the generation of reactive oxygen so as to induce apoptosis of the laryngeal cancer cells and cell cycle arrest. The pharmaceutical composition provided by the invention,when used for treating the laryngeal cancer, has the advantages of being obvious in antineoplastic effect and low in toxic and side effects.
Owner:TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE
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