110 results about "Trichosanthin" patented technology

The invention relates to a Chinese traditional patent medicine (the trade name being Rehmanniae Diabetes Capsule) for treating diabetes. The medicine comprises the following raw materials by weight portion: 30 to 60 portions of dwarf lilyturf tuber (also named dwarf lilyturf root), 30 to 60 portions of asparagus root (also named asparagus), 40 to 70 portions of figwort (also named radix scrophulariae), 70 to 150 portions of coptis root, 50 to 100 portions of oriental waterplantain rhizome, 20 to 50 portions of tuckahoe, 70 to 150 portions of cortex lycii radicis, 50 to 100 portions of tragacanth (also named radix astragali), 40 to 100 portions of cornus (also named cornus pulp), 30 to 60 portions of medlar, 50 to 100 portions of dry rehmanniae (also named fresh rehmanniae), 40 to 90 portions of prepared radix rehmanniae (also named prepared rhizome of rehmanniae), 20 to 60 portions of trichosanthin, 30 to 80 portions of panax, 20 to 40 portions of pilose antler and 50 to 100 portions of white muscardine silkworm. The Chinese traditional patent medicine plays a role in enhancing the sensibility of human body against insulin, reducing blood sugar and blood fat, regulating viscera and nourishing liver and kidney; moreover, the Chinese traditional patent medicine has scientific manufacturing process and can extract effective ingredients in raw materials.

The invention provides a medicine for remedying cancer, in particular to a medicine for remedying various cancers after surgery. The medicine is characterized in that No. I recipe takes radix rehmanniae, red peony root, bletilla, Szechwan lovage rhizome, wine-madder, salvia, panpax notoginseng, dandelion, APN, rhodiola himalensis, raw radix astragali, angelica, wolfberry fruit, chinese yam, radix pseudostell, membrane of chicken gizzard, asparagus, trichosanthin, hawthorn and so on as raw materials; No. II recipe takes vinegar leaching and frying turtle shell, dried lacquer, duchesnea indica, citrus aurantium, earth frying atractylodes, areca nut, mythic fungus, dodder, sang, raw ochre, pubescent holly, honeysuckleand so on as raw materials; No. III recipe takes sang, liriope, liquorices, cinnamon, herba cistanches, wolfberry fruit and so on as raw materials. The recipes are separately made into decoction in proportion. The medicine uses the comprehensive effect of each medicine to remedy various cancers that have been processed with surgery. The medicine can remove blood heat, influence blood, active blood without randomly influencing, stop blood, eliminate blood stasis, produce new blood and drain deteriorated blood without harm to new blood. The clinical treatment shows that the medicine has significant efficacy.

A traditional Chinese medicine for remedying the pneumonia belongs to the traditional Chinese medicine for remedying the pneumonia. The main prescription is 30 grams of gypsums, 5 grams of ephedra, 15 grams of bitter apricot seeds, 5 grams of liquorices, 30 grams of heartleaf houttuynia herbs, 24 grams of Baikal skullcap roots, 30 grams of taraxacums, 30 grams of giant knotweed rhizomes, 30 grams of common andrographis herbs and 15 grams of dyers woad leaves. The auxiliary prescriptions are that if the patient also has a chest ache, 10 grams of turmeric root tubers, 10 grams of fumitory and 10 grams of common aucklandia roots can be added; if the patient also has the serious asthma, 10 grams of mulberry barks and 15 grams of pepperweed seeds can be added; if the patient also has yellow, little or red emiction, 15 grams of plantain herbs and 10 grams of corktree barks can be added; if the patient also has fluid consumption because of intense heat, 15 grams of trichosanthin, 30 grams of reed rhizomes, 10 grams of tuber of dwarf lilyturf and 10 grams of dendrobium can be added. The compatibility of the traditional Chinese herbal medicines is simple; the medicines used in the medicine prescription are all natural herbal medicines which can be conveniently gotten and used; the manufacturing method is simple; the curative effect after being taken is good; the medicine price is cheap, and the medicine is especially fit for people who live at the remote small villages away from villages and towns to use. The treatment expense for the patient with the pneumonia is low, which solves the treatment problem, which is caused by low family income, poor living and lack of local medical treatment condition.

The invention discloses a traditional Chinese medicine ointment for eliminating carbuncle and ulcer, which is composed of the following ingredients: dandelion, purslane, indigo daisy, Patrinia, raw scutellaria, raw licorice, houttuynia, saponins, trichosanthes, and honeysuckle , Liga, Forsythia, Fangfeng, Anemarrhena, Honey. This product has a wide range of raw materials and low cost, and has the functions of antibacterial and anti-inflammatory, heat-clearing and detoxifying, detoxification and muscle growth, and improving the body's immunity. It is used to treat carbuncles, furuncles, furuncles, sores and other diseases that cause skin damage or ulceration due to various reasons. Just rub the affected area directly, the medicine is absorbed through the skin, the effect is good, the curative effect is fast, and the pain of the patient is reduced.

The invention discloses an allergic rhinitis particle which is prepared by the following components: 290 to 310 g of astragalus, 190 to 210 g of atractylodes, 18 to 22 g of asarum, 75 to 85 g of radixsaposhnikoviae, 95 to 105 g of angelica, 95 to 105 g of lily magnolia, 190 to 210 g of xanthium, 45 to 55 g of periostracum cicadae, 45 to 55 g of apiary, 8 to 12 g of spina gleditsiae, 95 to 105 g of pangolin, 190 to 210 g of red peony root, 95 to 105 g of balloonflower, 145 to 155 g of honeysuckle, 145 to 155 g of forsythia, 95 to 105 g of fritillary bulb, 95 to 105 g of trichosanthin, 95 to 105 g of schisandra and 45 to 55 g of glycyrrhiza. A preparation method comprises the following steps: extracting volatile oil from the atractylodes, the asarum, the radix saposhnikoviae, the angelica and the lily magnolia by a distillation method; collecting distilled water solution in another vessel; decocting the distilled herb residues and the other fourteen Chinese herbs twice by adding water for 1.5h for the first time and 1h for the second time; combining and filtering decoction solutions; combining filter liquor with the water solution to be concentrated to become clear paste with the relative density of 1.35 to 1.40 (50 DEG C to 60 DEG C); drying and crushing the clear paste into fine powders; adding proper sucrose powder, dextrin and ethanol into the fine powder to be prepared intoparticles; drying the particles; spraying volatile oil into the particles, uniformly mixing; and fractionally packing the particles. The allergic rhinitis particle is easy to take, has the efficacy of invigorating lung, strengthening spleen, dispelling wind and relieving stuffiness and has favorable curative effect on treating symptoms such as nasal obstruction, watery nasal discharge, sneezing and the like caused by allergic rhinitis.

The invention discloses a drug for treating faucitis. The drug is prepared from the following raw materials of traditional Chinese medicines, by weight: 10-12 parts of blackberry lily, 10-12 parts of angelica, 12-15 parts ofsubprostrate sophora, 15-20 parts of radix scrophulariae, 10-15 parts of mother chrysanthemum, 10-15 parts of Scutellariabaicalensis, 10-20 parts of honeysuckle, 10-12 parts of burdock, 15-20 parts of Fructus Forsythia, 12-15 parts of ThunbergFritillaryBulb, 10-12 parts of mulberry bark, 10-12 parts of radices trichosanthin, 10-12 parts of Indian Trum etflower Seed, 10-12 parts of liquorice and 8-10 parts of the root of balloonflower. The medicines are mixed and decocted with water for administration, and also can be ground for administration. The drug has efficacies of nourishing Yin for lowering fire, clearing throat, detoxifying, eliminating inflammation, promoting the secretion of saliva, moisturizing dryness inhibiting growth of inflammation bacteria, so as to achieve the purpose of fast curing for sore throat, and a total effective rate of 98.2%.

The invention relates to anti-AIDS nanometer Chinese medicine and a production method thereof. The anti-AIDS nanometer Chinese medicine comprises the following raw material composition of active ingredients in percentage by weight: dozens of kinds of Chinese medicine such as 40 to 50 of trichosanthin, 30 to 40 of scrophulariaceae, 30 to 40 of coptis, 40 to 50 of scutellaria and the like. The method comprises the production processes of pretreatment pulverization, high-frequency ultrasonic pulverization extraction dispersion, microwave leaching, supersonic speed spray drying pulverization, nanometer grinding, mixing, capsule filling and sterilization. The recipe has the antivirus and antitumor treatment effect, has no toxic or side effect, and is applicable to the treatment on tumor patients and patients with viruses such as HIV, HBV and the like. Through diagnosis and treatment, efficacy analysis, drug tropism, yin and yang identify identification, body resistance strengthening and evil eliminating, reasonable compatibility of assistant and guide medicine and the like, the recipe is divided into four preparations: a monitoring preparation, a noon preparation, an evening preparation and a night preparation which are respectively taken in four time intervals. The anti-AIDS nanometer Chinese medicine can also be used for local skin application and acupuncture point medication percutaneous absorption treatment on human bodies according to different periods.

The invention relates to a traditional Chinese medicine composition for treatment of diabetes, which comprises the following pharmaceutical raw materials by proportion: 10 - 25g of gypsum, 10 - 20g of dried rehmannia, 10 - 20g of prepared rehmannia, 10 - 25g of angelica, 10 - 25g of dangshen, 10 - 20g of trichosanthin, 10 - 20g of scrophularia, 10 - 20g of sweet potato flesh, 12 - 18g of polygonatum, 10 - 25g of Chinese yam, 12 - 20g of radix polygoni multiflori preparata, 10 - 20 g of medlar, 12 to 18g of asparagus fern, 12 - 18g of Radix Ophiopogonis, 8 - 15g of anemarrhena, 8 -15g of phellodendron, 10 - 20g of medicinal cyathula root, 4 -10gof red ginseng, and 100 - 500g of pear juice. The medicine has a simple treatment method, obvious efficacy, no side effects, and quickly disappeared clinical symptoms, and is convenient to use, the course of treatment is short, and the diabetes can be thoroughly eradicated, and can be cured without relapse. Through the clinical observation for 200 cases of patients suffered from the diabetes, the comprehensive effective rate reaches 98%, and the cure rate is 94% without relapse.

The invention discloses a Chinese herbal medicine composition for curing diabetes, comprising aweto, wolfberry bark, scutellaria, trichosanthin, liriope, kudzu, phellodendron bark, anemarrhena, root of rehmannia, xuanshen, schisandra, cassia bark, astragalus, Chinese yam, lanceolata, malt, medicated leaven, coix seed, crab apple and tartarian buckwheat root and rhizome. The preparation method of the Chinese herbal medicine composition comprises the following steps: wolfberry bark, scutellaria and liriope are boiled, immersed with trichosanthin and then dried; phellodendron bark, anemarrhena and root of rehmannia are boiled, immersed with kudzu and then dried; malt, medicated leaven and crab apple are boiled, evenly immersed with lanceolata and then dried; tartarian buckwheat root and rhizome, coix seed, cassia bark and aweto are dried; then, the dried trichosanthin, kudzu, Chinese yam and lanceolata are crushed and added to starch to make into pills with water. The Chinese herbal medicine composition can reinforce the sensibility of insulin, can obviously reduce lipid, regulate lipid and reduce blood viscosity, and has the advantages of simple making method, fast effects and stable therapeutic effects.

The present invention relates to the field of Trichosanthes planting, and discloses a group cultivation method of Trichosanthes trichosanthes, comprising the following steps: (1) selecting Trichosanthes root mass to accelerate germination in a suitable environment. Polysaccharides have the obvious effect of regulating cell division and have strong resistance. The various enzymes and amino acids contained in it make the sprouts strong in rooting, and the survival rate of seedlings is higher than that of seed culture; (2) the germination to The seed buds are peeled off from the basal bud tip, which has the highest hormone level, is non-toxic, has a fast meristem speed, and is easy to cultivate; (3) The ingredients in the medium are added with various nutrients required by the seedlings as the cultivation progresses (4) The seedlings obtained by tissue culture are adapted to the external environment and can be transplanted in the field after stabilization. The method for cultivating seedlings of the group of the present invention improves the character of Trichosanthes trichosanthis, has high and stable yield, and is beneficial to the accumulation of excellent characters.

The present invention relates to an erdong oral preparation and a method for preparing the same. The oral preparation is prepared from mixed extract (extractum or dry powder) including tiandong, liriope, trichosanthin, radix astragali, common anemarrhena, liquorice, genseng, lotus leaf as raw materials, and acceptable carrier or excipient as substrate in medicine by conventional process. The preparation has effects of nourishing yin and moisting lung, encouraging production of body fluids to extinguishthirst, cleaning wine heat, nourishing yin liquid, strengthening the spleen in transportation and protecting liver and stomach for treating diabetes involving upper, thirsty symptom etc.

The invention relates to Chinese patent medicine for treating diabetes mellitus and a preparation method thereof, which belongs to the technical field of Chinese patent medicine. The Chinese patent medicine is composed of the following Chinese traditional medicine materials in weight percentage: 30 to 50 portions of trichosanthin, 60 to 70 portions of schisandra chinensis, 50 to 60 portions of raw astragalus, 50 to 60 portions of polygonatum, 100 to 120 portions of plaster stone, 60 to 70 portions of ginseng, 30 to 40 portions of rehmanniae radix, steamed rehmannia, 70 to 80 portions of gegen, 20 to 30 portions of dried ginger, 30 to 30 portions of rhizome polygonatum, 30 to 40 portions of Chinese wolfberry root bark, 50 to 60 portions of gizzard membrane, 30 to 40 portions of loosestrife, 110 to 130 portions of folium pyrrosiae, 200 to 300 portions of balsam pear juice and 200 to 300 portions of guava leaf juice. The Chinese patent medicine is prepared through the processes of grinding, decocting, air drying, and the like. The compositions of the invention has the efficacies on nourishing liver and kidney, strengthening spleen and invigorating stomach, promoting fluid production extinguish thirst, lowering adverse qi for regulating stomach and decreasing sugar and lipid, and has favorable effect on the treatment of diabetes mellitus.

The invention discloses a method for comprehensively extracting diverse bioactive ingredients from radix trichosanthis. The method comprises the steps: firstly, adding ethanol into the radix trichosanthis, carrying out ultrasonic shaking, heating for extracting, carrying out suction filtration on an extract, and concentrating and drying a filtrate, so as to obtain an alcohol-soluble substance; extracting remnant filtrated residues, centrifuging an extract, treating a supernatant, and then, carrying out evaporative concentration and drying, so as to obtain water-soluble crude polysaccharides; adding a sodium hydroxide solution into remnant precipitates, carrying out heated extraction, centrifuging an extract, treating an obtained supernatant, so as to obtain precipitated alkali-soluble polysaccharides, and washing and drying, so as to obtain alkali-soluble crude polysaccharides; then, extracting radix trichosanthis protein from remnant precipitates, and then, further extracting radix trichosanthis agglutinin from remnant precipitates; finally, washing and baking remnant precipitates, thereby obtaining radix trichosanthis starch. By using the method, a variety of effective bioactive ingredients, namely the alcohol-soluble substance, the water-soluble polysaccharides, the alkali-soluble polysaccharides, the protein, the agglutinin and the starch, can be comprehensively extracted from the radix trichosanthis, so that radix trichosanthis resources are utilized to a greater extent, and then the current economic sustainable development is met.

The invention discloses a blood-glucose-lowering and pancreatic-islet-recovering plaster, and belongs to externally-used medicine for curing diabetes mellitus. The blood-glucose-lowering and pancreatic-islet-recovering plaster comprises radix scrophulariae, radix rehmanniae, liriope, trichosanthin, astragalus membranaceus, salvia miltiorrhiza, codonopsis pilosula, angelica sinensis, white muscardine silkworms, caulis spatholobi, cortex lycii radicis, quasi rhizoma dioscoreae, poria cocos, kudzu roots, schisandra chinensis, periostracum cicadae, coptis chinensis, salt-fried dodder, raw anemarrhena, raw gypsum powder, dark plums, bitter oranges, radix saposhnikoviae, rhizoma typhoon, pericarpium citri reticulatae viride, cistanche, cassia seeds, rhubarb, white peony roots, fenugreek, radix glycyrrhizae preparata, round-shaped rice, phenformin, glibenclamide and sesame oil, wherein each medicines acts synergistically. The blood-glucose-lowering and pancreatic-islet-recovering plaster performs the functions of yin nourishment, body strengthening, adverse Qi descending, stagnation elimination, liver clearing, vision improvement, yin-yang adjustment, kidney essence nourishment, blood nourishment and cooling, liquid engenderinging, thirst allaying, blood circulation promotion, stasis removal, meridian and collateral dredging, blood glucose lowering, pancreatic islet recovery, internal insulin secretion increase and recovery, global balance adjustment, metabolism enhancement, microcirculation improvement, prevention of the occurrence of cardiovascular and cerebrovascular diseases, nephropathy, nervous lesions and ophthalmopathy, and prevention of ketone toxicosis of elderly patients, and the like, achieves a good curative effect when being used for curing the diabetes mellitus, take effect quickly, achieve an effect of treating both principal and secondary aspects of diseases, and can reach a goal that the diseases have low probability of relapsing after being cured.

The invention discloses a traditional Chinese medicine combination for treating diabetes mellitus and the preparation method thereof. The traditional Chinese medicine combination is prepared by the raw medicines with the following weight parts: 100-300 parts of trichosanthin, 100-300 parts of yam, 20-80 parts of radix rehmanniae, 10-50 parts of red ginseng tails, 20-80 parts of radix astragali, 20-60 parts of wolfberry fruit, 10-50 parts of tuckahoe, 10-50 parts of rhizoma anemarrhenae, 10-50 parts of Alisma orientale, 10-50 parts of moutan bark, 5-30 parts of common macrocarpium fruit and 5-30 parts of malt. The traditional Chinese medicine combination of the invention has the efficacies of enriching yin, nourishing the kidney, invigorating qi, moisturizing the lung, easing thirst and promoting the production of body fluid. Proved by the observation results of clinical curative effect, the traditional Chinese medicine combination of the invention can effectively treat polyphagous, polydipsia, diuresis, weakness and tiredness, myasthenia of limbs, and so on caused by diabetes mellitus. The invention has safe clinical application and no toxic and side effect.

The invention relates to a Chinese traditional medicament composition for curing pedo-measles complicated with pneumonia in the Chinese patent medicament field. The technical proposal of the invention is that according to the medicament quantity each day, the proportion by weight is that peucedanum root 3g, almond 3g, mulberry leaves 3g, common anemarrhena 3g, liriope 3g, honeysuckle 9g, trichosanthin 3g, isatis root 9g, rhizoma corydalis 6g and liquorice 1.5g. The invention provides the medicament configuration for pedo-measles complicated with pneumonia. The invention has the efficacies of clearing heat, resolving phlegm, nourishing yin and detoxifying. Through the 56 cases of clinical trials, the cure rate is 39 cases, the effective rate is 47 cases, the side effect is small, and the curative effect is stable.

A traditional Chinese medicine for curing spleen deficiency phlegm-dampness acne belongs to a traditional Chinese medicine. The components contain: 30g of hawthorn fruit and 30g of coix seed, 20g of white hyacinth bean, 20g of tuckahoe, 15g of zedoray rhizome, 15g of pinellia tuber,15g of dried orange peel, 10g of largehead atractylodes rhizome, 10g of villous amomum fruit, 10g of lotus seed, 6g of golden thread and 6g of radix glycyrrhizae; the invention has the auxiliary prescriptions that: for the patients with too much uropygail, the hawthorn fruit is added to 50g of; for the patients with fatigue and acratia, 20g of tangshen is added; for the patients with continuous joint cyst, 10g of common selfheal fruit-spike, 10g of seaweed and 10g of peach seed are added; for the patients with dry mouth and lips, 15g of dwarf lilyturf tuber and 15g of trichosanthin are added; for the patients accompanied by irregular menstruation, 20g of Chinese angelica and 10g of motherwort herb are added. The compatibility of the traditional Chinese medicine is simple; the medicine used in the prescription is fully natural herbal medicine, which is easy to collect and use; the preparation method is simple; the effects for taking and curing are good; the cost of the medicine is low, and the medicine is in particular suitable for the people living in remote villages far from towns; the cost is low for curing the people suffering from spleen deficiency phlegm-dampness acne, which solves the problem that the local area lacks medical conditions to cure the disease because of low household income and poor living condition.

The invention relates to a new molecular identification method for identifying trichosanthin and its similar products; adventurous innovation is made in two key links of primer design and annealing temperature. Primer design is performed on a known ITS of trichosanthin medicinal materials; the length is about 20 bp; and general primer design principles are followed. Meanwhile, the annealing temperature is screened and determined according to the number of polymorphism strips. The characteristic identification strips of trichosanthin are determined to be 560, 960 bp strips, and 1930, 1400, 839, 715 bp strips are considered as auxiliary identification strips of trichosanthin. The invention has the following advantages of: (1) simplicity and practicality, wherein although the difficulty for primer design is increased slightly, the specificity is greatly improved, an ideal identification primer can be obtained after design of 2-3 primers, and thus the problem of large screening of random primers is avoided; (2) stability and repeatability, wherein since the specificity and annealing temperature of the primer are improved, the amplification strips are generally only 1-5 strips, and certified products with different producing areas and different storage time have no effect on PCR results; (3) large provided information content, wherein both certified products and most fake products can be amplified simultaneously, and thus standard identification electrophoretograms of the certified products and fake products can be established to realize accurate identification of the certified products and fake products.

The invention relates to a traditional Chinese medicine preparation which is a special plaster medicine treating facial furunculosis.The traditional Chinese medicinal combination used for treating diabetes mellitus is made by certain weight of cornus dogwood fruit, dioscorea root, fragrant solomonseal rhizome, glossy privet fruit, Chinese wolfberry fruit, dwarf lilyturf tuber, trichosanthin, fleeceflower root, Chinese wolfberry root-bark, villous amomum fruit and raw liquerice. Putting the material medicine into a marmite and adding water for proper soaking: first, using furious fire to boil, then using small fire to heat for half an hour. The liquid medicine is filtered, and proper water is added into the decoction medicine and heated for half an hour, and then the medicine liquid is filtered again. The twice liquid medicine is mixed together and is cooled. The medicine is respectively served half an hour before breakfast and two hours after supper.The traditional Chinese medicinal combination of the invention has short course of physical treating the diabetes mellitus, quick effect and without toxicity and side effect. The invention adopts the latest theory of traditional Chinese medicinal activated receptor Gamma, comprehensively condition organism to recover to a healthy state and fundamentally stabilize the blood sugar. The invention overcomes adverse reaction and dependency caused by long-time taking medicines of reducing blood sugar.

The invention relates to a traditional Chinese medicine for treating chloasma; the invention is a medicament prepared by the following raw materials by weight proportion through a conventional method: 5-8g of angelica, 8-10g of safflower, 8-10g of figwort, 5-8g of radix bupleuri, 5-10g of trichosanthin, 8-10g of red paeonia, 5-10g of rhizoma anemarrhenae, 10-20g of radix astragali, 8-12g of fried atractylodes rhizome, 6-10g of prepared nutgrass galingale rhizome and 1.5-3g of liquorice. The invention has rapid curative effect, short treatment course, high cure rate, low cost but no toxic and side effects at all; through the clinical application of patients, the cure rate reach 95 percent and the total effective rate can reach over 98 percent. Furthermore, the invention has significant treatment effect for the patients with stain and irregular menstruation. .

The invention relates to a group of traditional Chinese medicine trichosanthin derived peptides and application thereof. The technical proposal is as follows: a trichosanthin derived peptide p18 has the amino acid sequence shown by SEQ ID NO: 1; a trichosanthin derived peptide p18 tetramer has the amino acid sequence shown by SEQ ID NO: 2; and a trichosanthin derived peptide p14 has the amino acid sequence shown by SEQ ID NO: 3. The trichosanthin derived peptides achieve effects in the experimental study of treating sthenic immune response autoimmune diseases. The invention has the advantage that the invention makes a breakthrough in a traditional method, and removes the part of a trichosanthin molecular structure with toxic and side effects while retaining the effective bioactivity so as to develop a low-toxicity high-efficiency new preparation truly capable of treating a plurality of clinical diseases.

The invention relates to a TCS-cell penetrating peptide-tumor protease substrate peptide fusion protein and a preparation method thereof, further provides a TCS-cell penetrating peptide-tumor proteasesubstrate peptide fusion protein-lactoferrin linker and a preparation method thereof, and further relates to uses of the linker in preparation of drugs for treatment of tumors. According to the present invention, the TCS-cell penetrating peptide-tumor protease substrate peptide fusion protein can increase the cytotoxicity of Trichosanthin on tumor cells, and is used for the treatment of malignanttumors; and the linker can penetrate through the blood-brain barrier and can be accumulated in brain tumors, and can responsively and selectively kill tumor cells with high matrix metalloproteinase-2expression due to the high matrix metalloproteinase-2 expression in tumor cells so as to inhibit the growth of tumors and prolong survival period.

The invention belongs to the technical field of traditional Chinese medicines and in particular relates to a traditional Chinese medicine formula for treating thyroid carcinoma and a preparation method of granules of the traditional Chinese medicine formula. The traditional Chinese medicine is prepared from the following medicinal raw materials in parts by weight: 10-15 parts of root of catclaw buttercup, 6-8 parts of curcuma root, 10-15 parts of unibract fritillary bulb, 6-8 parts of laminaria japonica, 10-15 parts of kelp, 6-8 parts of prunella vulgaris, 10-15 parts of airpotato yam rhizome, 10-15 parts of ternate pinellia, 6-8 parts of green tangerine peel, 10-15 parts of radix bupleuri, 6-8 parts of dried tangerine peel, 6-8 parts of radix pseudostellariae, 6-8 parts of rhizoma polygonati, 6-8 parts of trichosanthin, 15-20 parts of spreading hedyotis herb, 10-15 parts of radix ophiopogonis, 10-15 parts of Chinese magnoliavine fruit, 10-15 parts of grass leaved sweetflag, 25-30 parts of radix adenophorea, 25-30 parts of glossy privet fruit, 15-20 parts of herba epimedii, 15-20 parts of rehmanniae radix, 15-20 parts of gambir plant and 25-30 parts of alga. According to the theory of the traditional Chinese medicines of strengthening and consolidating body resistance, promoting blood circulation and removing blood stasis, working along both lines of reducing phlegm and treating blood stasis, the traditional Chinese medicine has the efficacies of clearing away heat and toxins, reducing phlegm, resolving masses, activating blood, dredging channels, dissolving and eliminating swelling, tonifying qi and nourishing yin, has a good effect of treating the thyroid carcinoma and is fast in effect.

The invention relates to a bezoar antiphlogistic tablet, which is a Chinese herbal medicine compound preparation composed of seven traditional Chinese medicines, namely bezoar, mother-of-pearl, senso, natural Indigo, trichosanthin, rhubarb and realgar, and has the efficacies of heat-clearing and detoxifying and detumescence analgesic. The tablet is used for treating various symptoms such as swollen sore throat, boil, carbuncle, and scabies; the bezoar antiphlogistic tablet has the advantages of small taking dose, definite curative effect, etc. However, because the preparation has more animal drugs and toxic drugs, the clinical use is very cautious, and the quality standard of the actual bezoar antiphlogistic tablet cannot completely achieve the purpose of supervising drug safety yet. The bezoar antiphlogistic tablet aims to provide a more perfect quality control method on chemical makeup establishing and ration.

The invention provides a Health-preserving tea for treating diabetes, lowering blood pressure and blood lipid. The tea is composed of the following raw materials in parts by weight: Cyclocarya paliurus 10-15 parts, mulberry leaves 10-15 part, kudingcha 6-10 part, tuckahoe 1-4 part, yam 1- 5 part of liquorice, 5-10 parts, tartary buckwheat 1-4 part, cortex Lycii 1-4 part, honeysuckle 1-4 part of burdock root, 4 6 part, guava leaves 4-6, oats 1- 4 part, 4-6 polygonatum odoratum, corn whiskers 1-4, lotus leaf 4-6 parts, locust flower 4-6 parts, scrophulariae radix 1-4copies, raw rehmannia 1-4, Shudi 1- 4, Atractylodes macrocephala Koidz. 1-4, lentils 1-4 parts, cortex Mori 1-4, mulberry 5-10 parts, trichosanthin 1-4 part, 1-4 part, rhizoma anemarrhenae 1-4 part, litchi kernel 1-4 part, greenfruit 1-4 part, dendrobium 1-4 parts, cistanche deserticola 1-5 parts of fructus Alpiniae Oxyphyllae 1-4 part, 1-4 part, psoralea corylifolia 1-4 part, pilose antler 1-4, Hainan Sunken 1-4 part, ginseng 1-4 part, propolis 1-6 parts of polygonum multiflorum powder, 1-4 parts. The above prescription has remarkable curative effect on "three high" population.

The invention relates to a codon-optimized trichosanthin gene and application thereof in gene therapy. According to the invention, after codon optimization, the trichosanthin gene is subjected to drug delivery through a viral or non-viral vector, can express protein at a higher level in mammalian cells so as to play a greater biological role. In the invention, the drug delivery carrier is optimized to improve its transgenic expression level in mammalian cells and play a maximum antitumor role, thus having important significance to research and promotion of tumor gene therapy.

The invention discloses a snakehead feed with the addition of donkey-hide gelatin. The snakehead feed is characterized by being prepared from the raw materials in parts by weight: 5-7 parts of fish meal, 10-13 parts of marbled meat, 4-8 parts of corn protamine, 14-18 parts of corn flour, 17-20 parts of fermented soybean meal, 18-22 parts of adzuki bean, 19-25 parts of expanded soybean, 6-9 parts of vine tea, 1-2 parts of lotus leaf extract, 10-13 parts of lily, 15-18 parts of cucumber, 2-3 parts of fish oil, 5-9 parts of elm leaf, 0.2-0.4 part of donkey-hide gelatin, 0.1-0.2 part of astragalus, 0.3-0.5 part of trichosanthin, 5-8 parts of an additive and a proper amount of water. Compared with the traditional feed, the snakehead feed with the addition of the donkey hide-gelatin has the efficacies of moistening the lung and soothing the nerves and has the advantages of comprehensive nutrition, little pollution to aquaculture water and wide raw material sources. After snakehead is fed with the snakehead feed, the feeding rate and the weight gaining speed of the snakehead can be increased.

A drug for treating AIDS and a preparation method thereof, which is characterized in that it is mainly made of the following raw materials in parts by weight: 6-9 parts of paeonol, 3-6 parts of trichosanthin, 3-6 parts of Ganoderma lucidum, 3-5 parts of Rehmannia, 3-5 parts of peony root, 3-5 parts of cassia twig, 3-6 parts of citrus aurantium, 2-5 parts of bellflower, 2-5 parts of ginger, 1-3 parts of jujube, and 1-3 parts of licorice. It is made into dry powder by extraction and drying, and can be prepared into various dosage forms as required. The medicine of the invention has the functions of consolidating the body and strengthening the body, nourishing yin and suppressing yang, clearing heat and detoxifying, reducing inflammation and analgesia, and enhancing immunity, and has certain curative effects on treating AIDS and resisting various viruses.

The invention belongs to the medical field, and relates to an application of a pharmaceutical composition in preparing a medicament for reducing SREBP1-c, wherein the pharmaceutical composition is prepared by the following traditional Chinese medicine raw materials by weight: 540 parts of trichosanthin, 10-30 parts of radix bupleuri, 3-15 parts of citrus aurantium, 1-6 parts of raw rhubarb, 1-12 parts of pinellia tuberifera, 3-15 parts of radix scutellariae, 1-12 parts of coptis, 3-15 parts of white peony roots, and 5-20 parts of dark plums.

The present invention belongs to the technical field of veterinary drug production and particularly to a liquid traditional Chinese medicine preparation for preventing African swine fever and a methodof the liquid traditional Chinese medicine preparation. The liquid traditional Chinese medicine preparation comprises the following raw materials: spreading hedyotis herb, dandelion, bunge corydalisherb, herba patriniae, glabrous greenbrier rhizome, wild chrysanthemum flowers, vietnamese sophora root, lightyellow sophora root, muskroot-like semiaquilegia root, common andrographis herb, barbed skullcap herb, baical skullcap root and rhizoma coptidis. The preparation process flow of the traditional Chinese medicine preparation sequentially comprises the following steps: a raw material washingand crushing step, a decocting step, a filtering step, a purifying step and a filling step. The liquid Chinese medicine preparation has a function of resisting pathogenic microorganisms, effective active ingredients such as camptothecin, trichosanthin, harringtonine, etc. are separated from the liquid Chinese medicine preparation, parts of the active ingredients can also widely influence differentaspects and links of organism immune functions, and the liquid traditional Chinese medicine preparation has good directivity and inhibition functions on viruses, funguses and bacteria and thus can very well prevent and treat the African swine fever.