220results about How to "Improve biological performance" patented technology

An implantable medical device including a porous membrane that is treated with a hydrophilic substance to obtain rapid optimum visualization using technology for viewing inside of a mammalian body. These technologies include ultrasound echocardiography and video imaging such as that used during laparoscopic procedures.

Disclosed are compounds of Formula 1, N-oxides, and salts thereof,whereinJ isand R1, R2, R3, R4, R5, R6, R7, R8a, R8b, R8c, G1, G2, G3, G4, G5, G6, Q1, Q2, Q3, Q4, W1, W2, Y1, Y2, Y3, m and n are as defined in the disclosure.Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of a compound or a composition of the invention.

The invention discloses a method for preparing antibacterial nanometer silver colloid, belonging to the technical field of nanometer biological materials. The method uses a chemical reduction method, comprising the following steps: dissolving water-soluble protective agent in silver nitrate water solution with the concentration of 0.001-0.1mol / L, wherein the mass ratio of protective agent to silver nitrate is 0.5-10.0:1; carrying out ice bath on sodium borohydride water solution with the concentration of 0.001-0.2mol / L for 10-30min; and dropwise adding the silver nitrate water solution containing protective agent in the sodium borohydride water solution with the speed of 30-60 drop / min, stirring by a magnetic stirrer, stirring for 20-40min after dropwise adding to prepare the nanometer silver colloid with the grain size of 5-80nm, wherein the mol ratio of the sodium borohydride to the silver nitrate is 1.0-30.0:1. The nanometer silver colloid prepared by the invention has the advantages of high concentration, high stability, high dispensability, and obviously-enhanced antibacterial property.

A synergistic insecticidal composition is formed containing a Chloronicotynyle compound and a Pyrethroids compound. The Chloronicotynyle compound is provided in an amount preferably ranging from 0.1 to 5.0% by weight of the synergistic insecticidal composition. The Pyrethroids compound is provided in an amount preferably ranging from 1 to 60% by weight of the synergistic insecticidal composition. The synergistic insecticidal composition also preferably includes 35 to 98.90% by weight of conventional agriculturally acceptable carrier(s) and / or excipients.

The invention provides a collateral-dredging lipid reduction product comprising active materials of black tea and a preparation method; the product consists of extracts of Anhua Red Tea and drug-food homologous substances; the preparation method of the invention produces a special and brand-new preparation method resulting from the formula specialty; the invention has the comprehensive functions of collateral dredging, lipid reduction, sugar reduction, decompression and weight reduction.

Disclosed are compounds of Formula 1, N-oxides, and salts thereof,wherein W1 is O or S, and R1, R2, R3, G and J are as defined in the disclosure.Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling undesired vegetation comprising contacting the undesired vegetation or its environment with an effective amount of a compound or a composition of the invention.

The invention discloses a constructing method of stem cell breeding and differentiation microenvironment in vitro in the stem cell tissue engineering domain, which comprises the following steps: adopting sodium alginate and polylysine as material to prepare APA microencapsulation ES cell; adding microencapsulation ES cell in the ES growing culture medium; stewing at 37 Deg C in the culture box with 5% CO2; changing culture medium every 2-3d to obtain the product. The invention simplifies the operation to generate high-density and large scale augmentation, which can inhibit or delay the oriental differentiation for ES cell.

The invention relates to a DNA origami-based construction method and an application of a precise recognition targeted nano-carrier, and belongs to the technical field of medicines. The carrier is composed of scaffold DNA, staple single-stranded DNA, special staple single-stranded DNA and a nucleic acid aptamer, wherein a molar ratio of the scaffold DNA to the staple single-stranded DNA to the special staple single-stranded DNA is 1:(5-10):(5-10); a molar ratio of the nucleic acid aptamer to origami is 1:(1-32); a molar ratio of the carrier to an antitumor medicine doxorubicin during drug loading is 1:(12500-50000); and the appropriate drug loading time is 2-6 h. The targeted nano-carrier has the advantages of realization of a target heat accurately-modified NDA carrier, improvement of the targeting effect of the carrier and the target heat induced biological effects, delaying of the drug release after drug loading, reduction of the toxic and side effects of anthracene ring antitumor drugs, and enhancement of the antitumor effect on tumor cells, and makes a drug-loaded system simultaneously perform chemotherapy effects and biotherapy effects.

The present invention provides a method for preparing organic biological fertilizer and fly-maggot protein by using domestic muscidian larva to treat chicken manure. It includes the following procedures of fly culture, fly-blows production, fly-blows collection, fly-blows inoculation, chicken manure treatment, fly and maggot separation, processing biological fertilizer and processing fly-maggot protein, so that the odourless chicken manure biological fertilizer and fly-maggot protein product can be obtained.

A catheter system for delivering ultrasonic energy to a treatment site includes a tubular body having a proximal end, a distal end and a treatment zone located between the distal end and the proximal end. An ultrasonic assembly is positioned within the treatment zone and provides providing an average longitudinal power density between about 0.2 and about 1.0 W / cm within the treatment zone.

A process for treating water that includes ammonium. The water is directed to a biological reactor and the quantity of nitrates formed in the reactor and the quantity of ammonium reduced in the reactor is determined. A ratio of the quantity of nitrates formed to the quantity of ammonium reduced is determined. Further, the percentage of ammonium reduced is also determined. The water in the biological reactor is aerated by injecting oxygen into the reactor where the amount of oxygen injected is a function of the ratio and the percentage of ammonium reduced in the reactor.

The present invention provides a return sludge settler changed by an inclined tube settler, characterized in that the upper reation region is set with a mixing region and a promoting flocculation zone, a blender is set in the mixing region, a promoting mixer and an attachable stainless steel cylinder are set in the promoting flocculation zone, a baffle system is set between a filtering zone and a inclined tube water outlet, a mud zone sets a plug concentrating mud scraper, the mud pipe is connected with a mud runback to water inlet, the mud runback is set with a mud reflux pump, the mud runback is connected with exterior, and a medical feeding point is set in the water inlet and the main settler. The advantages of the invention is that giving full play impact to index such as biological degradation organic matter, nitrogen and phosphorus etc nu changing traditional inclined tube settler, enhancing coagulation efficiency by high effect mixing and mud return, thus the effluent effect is improved, and the solid ratio of the drainable sludge is enhanced, meeting the direct dehydration condition.

The invention discloses an improved fertilizer for saline and alkaline land and a preparation method of the improved fertilizer. The improved fertilizer for the saline and alkaline land is prepared from the following raw materials in parts by weight: 25-28 parts of maleic anhydride, 15-20 parts of citric acid, 20-30 parts of calcium superphosphate, 10-12 parts of a sodium ion adsorbent, 2-4 parts of a microbial agent, 25-32 parts of fulvic acid, 15-20 parts of a trace element fertilizer, 30-38 parts of a chicken manure fermentation fertilizer, 20-35 parts of peat, 3-5 parts of perlite, 5-8 parts of vermiculite and 20-25 parts of smashed straw particles. The invention further provides the preparation method of the improved fertilizer for the saline and alkaline land. According to the improved fertilizer for the saline and alkaline land, various soil improving measures can be synthesized, effects of reducing salt and alkali for the saline and alkaline land are good, the water content of the soil is high, the water retention property and the fertilizer retention property of the soil are good, besides, the survival rate of planted plants is high, and virtuous cycle of the soil of the saline and alkaline land is realized.

The invention relates to a method for preparing a porous bone scaffold by laser and increasing mechanical and biological performances of the porous bone scaffold by adding zinc oxide with little amount, which belongs to the bone tissue engineering field. Aiming at uncontrollable performances of aperture distribution, shape, space direction and connectivity in the preparation method of a traditional bone scaffold, and aiming at the disadvantages of poor mechanical property and fast resolving rate existed in tricalcium phosphate (beta-TCP), the invention provides the method for preparing the porous bone scaffold by using a selective laser sintering (SLS) technology, and provides the method for increasing performance by adding zinc oxide (ZnO). The method for preparing the porous bone scaffold has the advantages that the porous scaffold which enables three-dimensional interconnection is prepared by SLS, zinc oxide with little amount is added for introducing into a liquid phase, the particles densification can be promoted, crystal grain is refined, and the mechanical performance is improved, simultaneously, cell compatibility is increased, the degradation rate is reduced, and the biological performance is increased, so that the interconnected porous beta-TCP bone scaffold with enhanced mechanical performance and good biological performance can be finally prepared. The method has the advantages of simple preparation technology, convenient operation, low cost, easy control of technical parameter and the like.

The invention relates to a beauty-slimming product containing dark green tea Euro-tium cristatum and a preparation method therof. The beauty-slimming product comprises Euro-tium cristatum which is active ingredient of Anhua dark green tea, and a plurality of extracts of medicine and food homologue, and has good real weight-reducing effect and the comprehensive function of lipid-lowering, glucose-lowering, and hypotensive action at the same time.

The invention discloses a Chinese herb extract feed additive capable of effectively preventing and treating porcine epizootic diarrhea, and belongs to the field of feed additives. The feed additive is prepared from the main materials of snow grass meal, curcuma powder, semen cassiae powder, burdock powder, shallot white powder, Chinese herbal medicine preparation and curcuma extract, and toadstool and bacillus subtilis are scientifically compounded, so that the application amount of antibiotics medicine in cultivation of pigs is effectively reduced, the use amount of the antibiotic is reduced by above 60%, the drug property of the Chinese herbal medicine is improved, the porcine epizootic diarrhea caused by porcine epidemic diarrhea virus can be effectively prevented and treated, and the Chinese herb extract feed additive is safe and non-toxic. Besides, the amount of the additive in the feed is low, the quality is stable, an acting effect is improved by combining different Chinese herb extracts, the porcine epizootic diarrhea is reduced by 60-80%, and the taste and quality of animal products are obviously improved. A sense experimental evaluation proves that the evaluation score on the taste and quality of the animal products using the additive is improved by above 65%.

The invention discloses a composite bionic bone material and a preparation method thereof, and in particular relates to a hydroxyapatite / silk fibroin composite bionic material and a preparation method thereof, belonging to the technical field of medical materials. The composite material comprises the following components in percent by mass: 40-60 percent of hydroxyapatite, 10-30 percent of wollastonite and 25-35 percent of silk fibroin. On the basis of tight matching and higher biological property of the hydroxyapatite / silk fibroin material, the wollastonite with better biological property and mechanical behavior is introduced, the mechanical behavior of the composite material is greatly improved without influencing the biological property, the three materials are compounded to obtain a bone tissue coloboma repairing material perfectly combining the mechanical behavior with the bioactivity and compatibility, and the bone tissue coloboma repairing material has better practicability andapplication prospect.

The invention relates to a medical beta-titanium alloy composite material with osteogenesis inducting activity and a preparation method thereof. The material comprises a base material and a titanium oxide nano-tube array layer, which is generated in-situ and attached to the surface of the base material and contains BMP-2 cell growth factors. The base material is a medical beta-titanium alloy of the Ti-25Nb-6Zr-xMo family, wherein the x is between 2 and 5. The diameters of nano-tubes, which are generated in-situ on the alloy surface, are between 30 and 50 nm, the lengths of the nano-tubes are between 200 and 300 nm, and the nano-tubes are arranged in arrays and perpendicular to the surface of the titanium alloy. The medical beta-titanium alloy composite material has ultra-low elastic modulus and is capable of forming better interface mechanic matching with the bone tissue. So osteoblasts grow rapidly along the wall on the surface of medical beita-titanium alloy whose surface is loaded with titanium oxide nano-tube biological composite material containing BMP-2, and proliferate obviously. The composite material has a good effect on inducing osteoblasts to proliferate to form bone matrix and can be used to bone replacement or repairing.

Stabilized liquid agrochemical compositions are provided that comprise flowable, aqueous dispersion concentrates comprising a) a continuous aqueous liquid phase; b) at least one dispersed, solid phase comprising a dispersion of polymer particles having a mean particle size of at least one micron, wherein the outside surfaces of the particles comprise a colloidal solid material and wherein the particles have at least one agrochemically active ingredient distributed therein, optionally a non-porous particulate mineral that acts as a diffusion barrier to slow the release of the active ingredient, and optionally at least one non-cross-linkable mobile chemical such that the extraction of this chemical from the disperse phase renders it porous in a manner that allows the active ingredient to diffuse out. The colloidal solid is used to stabilize the polymenzable resin in an emulsion state during preparation.

The invention relates to compounds that exhibit improved bioefficacy in multidose administration. More specifically, the invention relates to polypeptides or peptides modified to include an antibody Fc region and one or more water soluble polymers.

The invention discloses a composite feed supplement capable of effectively improving the feed utilization ratio and preparation thereof and belongs to the field of feed supplements. The feed supplement comprises the following raw materials in parts by weight: 20-30 parts of radix asparagi powder, 20-35 parts of echinacea powder, 15-30 parts of cattail pollen powder, 20-30 parts of dogwood powder, 1-5 part (s) of cordyceps taishanensis powder, 1-5 part (s) of cordyceps sinensis fermentation liquor extractive, 2-8 parts of bacillus natto agent, 5-10 parts of radix asparagi composite extractive, 2-4 parts of Aspergillus awamori culture and 0.5-2 part (s) of licorice powder. The raw materials are respectively prepared by a certain methods and are uniformly mixed to obtain the composite feed supplement. The composite feed supplement can effectively improve the immunity and intestinal health of pigs, reduce diseases of pigs, ensure healthiness of pigs, promote growth and development, and simultaneously protect the feed against mildew and nutrient substances against oxidation loss, thereby improving the feed utilization ratio.

A synergistic insecticidal composition is formed containing a Chloronicotynyle compound and a Pyrethroids compound. The Chloronicotynyle compound is provided in an amount preferably ranging from 0.1 to 5.0% by weight of the synergistic insecticidal composition. The Pyrethroids compound is provided in an amount preferably ranging from 1 to 60% by weight of the synergistic insecticidal composition. The synergistic insecticidal composition also preferably includes 35 to 98.90% by weight of conventional agriculturally acceptable carrier(s) and / or excipients.

The present invention generally relates to salts of S-(+)-abscisic acid having enhanced performance, aqueous liquid compositions containing these enhanced performance salts of S-(+)-abscisic acid and methods of their preparation for agricultural use.

A synergistic insecticidal composition is prepared by combining a Chloronicotynyle compound and an Organophosphorus (OP) compound. The preferred synergistically effective amount of the Chloronicotynyle compounds is an amount preferably ranging from 0.1 to 5% by weight of the composition. The preferred synergistically effective amount of the Organophosphorus (OP) compounds is an amount preferably ranging from 30 to 75% by weight of the composition. The composition also preferably includes 69.9 to 20% by weight of conventional agriculturally acceptable carrier(s) and / or excipient.

The invention relates to a bioactive porous poly-ether-ether-ketone material and a preparation method and application thereof. The active porous poly-ether-ether-ketone material has a pore diameter of450-800 [mu] m and a porosity of 30-95%, and hydroxyapatite microspheres are contained on the inner surfaces of pores. The preparation method comprises the following steps: uniformly adhering the hydroxyapatite microspheres to the surfaces of NaCl particles, performing sintering to obtain composite pore-forming particles, uniformly mixing the composite pore-forming particles with poly-ether-ether-ketone, performing compacting, performing sintering, and finally removing NaCl to obtain the porous poly-ether-ether-ketone material. Osteogenesis promoting medicines and antibacterial medicines canbe loaded into the material according to needs, and the hydroxyapatite microspheres on the inner surface are added, so that the bioinertness of the poly-ether-ether-ketone can be effectively improved,the poly-ether-ether-ketone has bioactivity, the medicines and growth factors can be loaded, a good slow release effect is achieved, and good osteogenesis promoting and antibacterial properties are achieved. The bioactive porous poly-ether-ether-ketone material disclosed by the invention has the advantages of simple process, low cost, controllable structure, convenient drug loading and the like.

A variety of medical devices including staples sutures and dental floss with surface treatment on at least one tissue-facing surface to improve biologic function such as to control tissue adhesion are disclosed including heparin surface treatment which provides heparin present in an amount to yield heparin bioactivity of at least one of i) an ATIII binding of at least 2 pmol / cm2, and ii) a thrombin deactivation of at least 0.2 IU / cm2; an acrylic surface treatment for coupling thereto of a heparin surface treatment, a collagen surface treatment or both; and an amino-functional polysiloxane surface treatment for coupling thereto of a heparin surface treatment.

The invention provides a bioactive porous hybrid carbon nanofiber material and a preparation method thereof, and belongs to the technical field of biological composite materials. The bioactive porous hybrid carbon nanofiber material is prepared by virtue of a process comprising the steps of evenly mixing a precursor sol-gel liquid of a bioactive substance, polyacrylonitrile, a pore-foaming agent and an organic solvent together under the conditions of heating in a water bath and ultrasonics, aging to obtain a spinning solution, forming a primary nanofiber film by virtue of an electrostatic spinning process, and then carrying out hot-stretching, pre-oxidating in heating stage by stage and carbonizing, and a preparation method of the bioactive porous hybrid carbon nanofiber material. Due to the bioactive nanoparticles existing on the surface of the material, the material has biocompatibility, bioactivity and biodegradability; due to existing regular-structure nano-scale pores, the material has the relatively high specific surface area, and therefore, the biological properties of the material are greatly improved. As a result, the bioactive porous hybrid carbon nanofiber material can be further used as a novel bone repair material or a bone tissue scaffold reinforcing material.

An implantable medical device including a porous membrane that is treated with a hydrophilic substance to obtain rapid optimum visualization using technology for viewing inside of a mammalian body. These technologies include ultrasound echocardiography and video imaging such as that used during laparoscopic procedures.

The present disclosure relates to pharmaceutically acceptable complex formulae comprising complexes of Abiraterone acetate and pharmaceutically acceptable excipients, process for the preparation thereof and pharmaceutical compositions containing them. The complex formulae of the present disclosure have improved physicochemical properties which results in reduced food effect which allows significant dose reduction and the abandoning of the requirement of taking the drug on an empty stomach.

The present ivnention provides a method for combining nano material technology with peat and adopts different formulae and additives to form natural environment-protecting series products with several functions, several varieties and several purposes. Said nano material comprises compounds and oxides of nano metal and nonmetal, and the peat is the screened impurities (including sand and stone)-removed low-grade or high-grade peat whose organic substance content is above 50%, fibre content is above 35% and water content is 15-35%. Its concrete application includes (1). nano peat plant culture nutrient mechanism; (2) nano peat high-effective water and soil improvement environment-protecting nutrients mechanism; (3) nano peat pollution prevention and control mechanism; and (4) nano peat refuse degradation natural activity mechanism.