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Methods and systems for long term monitoring of one or more physiological parameters such as respiration, heart rate, body temperature, electrical heart activity, blood oxygenation, blood flow velocity, blood pressure, intracranial pressure, the presence of emboli in the blood stream and electrical brain activity are provided. Data is acquired non-invasively using ambulatory data acquisition techniques.

A method for filling recesses of a substrate with an insulation film includes: (i) exposing surfaces of the recesses of the substrate to a pre-deposition gas in a reactive state in a reaction space to treat the surfaces with reactive hydrocarbons generated from the pre-deposition gas without filling the recesses; and (ii) depositing a flowable insulation film using a process gas other than the pre-deposition gas on a surface of the substrate to fill the recesses treated in step (i) therewith by plasma reaction. The pre-deposition gas has at least one hydrocarbon unit in its molecule.

The application concerns methods of treatment using anti-ErbB receptor antibody-maytansinoid conjugates, and articles of manufacture suitable for use in such methods. In particular, the invention concerns ErbB receptor-directed cancer therapies, using anri-ErbB receptor antibody-maytansinoid conjugates.

Methods and apparatus, including computer program products, for interacting with a user to define business rules in a declarative manner. The invention operates to display a rule set as an editable list of conditions and an editable list of actions, the conditions and actions being linked to each other by the combination of an editable list of if-values and an editable list of then-values, wherein if-values and then-values are explicitly linked to each other, conditions and if-values are explicitly linked to each other, and then-values and actions are explicitly linked to each other in the displayed lists.

A device for capturing an embolus within a vessel of a patient's body has at least one helix made of a mesh material. The at least one helix has a plurality of turns helically arranged around a longitudinal axis. The mesh material has a plurality of pores therein and the pores have a size ≧120 μm. The at least one helix includes a plurality of panels wherein the panels are movable from a collapsed state to an expanded state when placed within a vessel. The mesh material is made of a self-expanding material such as nickel titanium in one embodiment. In another embodiment, the device has a double helix arrangement.

A projectile comprised of an ogive section, a bearing surface section and a boattail section. A cavity is formed inside the projectile from an aperture on the aft end of the boattail section and forward to about the transition point (shoulder) between the ogive section and bearing surface section. The cavity is centered about the centerline of the projectile and open on the aft end of the projectile.

The presently claimed invention provides methods and kits for amplifying a target sequence from within a nucleic acid population. The presently claimed invention provides selection probes which are complementary to at least a portion of said target sequence and mechanisms for adding a probe sequence to the 3' end of a target sequence that is hybridized to a selection probe. The added 3' probe sequence and a probe sequence added at the 5' end of the target by adaptor ligation allow for selective amplification of the target sequence.< / PTEXT>

A composition comprising dihydropyrazinyl anions that can be coordinated as 6 electron ligands to a broad range of different metals to yield volatile metal complexes for ALD and CVD depositions are described herein. Also described herein are undeprotonated dihydropyrazines that can coordinate to metals as stabilizing neutral ligands. In one embodiment, the composition is used for the direct liquid injection delivery of the metal dihydropyrazinyl complex precursor to the chamber of an ALD or CVD chamber for the deposition of metal-containing thin films such as, for example, ruthenium or cobalt metal films.

A method for capturing an embolus within a vessel of a patient's body includes the steps of providing a device having at least one helix made of a mesh material. The at least one helix has a plurality of turns helically arranged around a longitudinal axis. The mesh material has a plurality of pores therein wherein the pores have a size ≧120 μm. The device is placed within the vessel of the patient's body by moving the device from a collapsed state to an expanded state.

Methods and apparatus, including computer program products, for interacting with a user to define business rules in a declarative manner. The invention operates to display a set of business rules as editable conditions and editable actions, the conditions and the actions being linked to each other by a combination of editable if-values and editable then-values.

A tiny electrically powered hydrodynamic blood pump is disclosed which occupies one third of the aortic or pulmonary valve position, and pumps directly from the left ventricle to the aorta or from the right ventricle to the pulmonary artery. The device is configured to exactly match or approximate the space of one leaflet and sinus of valsalva, with part of the device supported in the outflow tract of the ventricular cavity adjacent to the valve. In the configuration used, two leaflets of the natural tri-leaflet valve remain functional and the pump resides where the third leaflet had been. When implanted, the outer surface of the device includes two faces against which the two valve leaflets seal when closed. To obtain the best valve function, the shape of these faces may be custom fabricated to match the individual patient's valve geometry based on high resolution three dimensional CT or MRI images. Another embodiment of the invention discloses a combined two leaflet tissue valve with the miniature blood pump supported in the position usually occupied by the third leaflet. Either stented or un-stented tissue valves may be used. This structure preserves two thirds of the valve annulus area for ejection of blood by the natural ventricle, with excellent washing of the aortic root and interface of the blood pump to the heart. In the aortic position, the blood pump is positioned in the non-coronary cusp. A major advantage of the transvalvular VAD is the elimination of both the inflow and outflow cannulae usually required with heart assist devices.

A method and apparatus is disclosed for making predictions about entities represented in documents and for information analysis of text documents or the like, from a large number of such documents. Predictive models are executed responsive to variables derived from canonical documents to determine documents containing desired attributes or characteristics. The canonical documents are derived from standardized documents, which, in turn, are derived from original documents.

The presently claimed invention provides methods and kits for amplifying a target sequence from within a nucleic acid population. The presently claimed invention provides selection probes which are complementary to at least a portion of said target sequence and mechanisms for adding a probe sequence to the 3' end of a target sequence that is hybridized to a selection probe. The added 3' probe sequence and a probe sequence added at the 5' end of the target by adaptor ligation allow for selective amplification of the target sequence.

Essential-oil compositions comprising Lippia javanica essential oil in combination with one, two, three, four, five, six or more essential oils are provided. The Lippia javanica essential-oil compositions are effective for killing and / or repelling ectoparasites and / or pests, including lice, ticks, mosquitoes, mites, ants and fleas. Methods of using the compositions comprising Lippia javanica essential oil in combination with one, two, three, four, five, six or more essential oils for killing or repelling ectoparasites and / or pests also are provided. Also provided are articles of manufacture and kits that include the Lippia javanica essential-oil compositions.

An object detection system is provided that projects one or more patterns onto a monitored area, captures one or more live images of the monitored area, and detects objects that enter the monitored area by detecting changes in the one or more patterns in the live images. Such an object detection system may be less susceptible to dynamic lighting conditions, and more sensitive to object motion and / or presence.

Apparatus suitable for transporting and storing nuclear fuel rods comprising a basket having storage cells formed from a honeycomb gridwork of metal plates in a rectilinear configuration, the plates welded to each other at their intersections so that all contiguous corners of the storage cells formed by the gridwork are completely connected so as to allow conduction heat transfer, the metal plates having neutron absorber material positioned in areas which form walls of the storage cells. Method of making an apparatus suitable for transporting and storing nuclear fuel rods comprising a) providing metal plates having slots and having neutron absorber material positioned on sides of the metal plates, b) arranging the plates so that the slots intersect to form a honeycomb gridwork of storage cells having contiguous corners and having the neutron absorbing material on sides of the storage cells, and c) welding the plates to each other at their intersections so that all contiguous corners of the storage cells formed by the gridwork are completely connected so as to allow conduction heat transfer and to provide a rigid structure.

An oligomer mixture of n-propylethoxysiloxanes, containing from 80 to 100% by weight of n-propylethoxysiloxanes having a degree of oligomerization ranging from 2 to 6.

The invention is based on the discovery that certain membranes, which include side chains or molecular “brushes” having, for example, tertiary amino functional groups, can be used as highly effective filters to capture viruses / virus particles from liquids without removal of proteins. New methods based on this discovery include removing viruses from liquids such as blood or plasma, removing viruses from pharmaceuticals, concentrating and / or purifying viruses, e.g., for use in gene therapy, and producing recombinant viruses in new bioreactors. The invention also includes new methods of therapy or adjunct therapy for viral infections, in which a patient's blood or plasma is filtered through the membranes to remove viruses to reduce the viral load. The invention also includes new bioreactors and viral filters containing the membranes.

The provides compounds for the treatment of sickle-cell disease. In particular, the invention provides 5-membered heterocyclic anti-sickling agents that are highly effective and non-toxic, and methods for their use. The compounds include analogues and derivatives of naturally occurring occurring 5-hydroxymethyl-2-furfuraldehyde, 5-Ethyl-2-furfuraldehyde, 5-Methyl-2-furfuraldehyde, and 2-furfuraldehyde, and prodrug forms of the compound.

This invention concerns a method for stimulating barrier integrity in a subject by administering to a subject a composition comprising docosapentaenoic acid (22:5 n3; DPA). Also the invention concerns a composition comprising DPA and eicosapentaenoic acid (EPA).

A three dimensional shape correlation computer software program which uses laser radar data for target identification. The correlation program obtains a scan of laser radar data of a target from a Ladar sensor. The data includes a plurality of X,Y,Z coordinate detection points for the target. The software simulates the sensor scan using a 3D wire-frame model of the target. An X,Y,Z coordinate location is computed for every point in the computer model of the target. The software compares the X,Y,Z coordinate detection points for the target with the X,Y,Z coordinate points for the computer model to determine if the points match. When there is a match a target identification is declared.

A process and device are disclosed for precipitating solid compounds from the liquid zinc or liquid zinc-based alloys of a metal bath. According to the disclosed process, partial amounts of the metal phase containing the compound(s) are exposed to an acceleration higher than the acceleration due to gravity and at least partially dissociated thereby into fractions containing heavier and / or lighter components. The molten mass depleted of solid compounds is returned to the metal bath and the part of the molten mass enriched with the desired compounds is discharged. The disclosed device is substantially characterized in that a hollow rotary body (2) is introduced into the molten mass (1). The hollow rotary body (2) can be driven about an axis and is fitted in the submerged or lower area with conveyor means (21) which project into the cavity. In its discharge or upper area, the hollow rotary body (2) is provided with at least one discharge opening (23) for the depleted molten mass (14) eccentrically arranged in its wall and with at least one further discharge opening (25) for the liquid metal enriched with the desired compounds centrally arranged and / or eccentrically arranged on the discharge side. At least one of the upper molten mass discharge openings (23, 24) in the rotary body (2) opens into a discharge area of a housing (3) which at least partially surrounds the rotary body (2).

The present invention relates generally to computer software, and more specifically, to a system and method of foiling buffer-overflow and alien-code attacks. The invention protects computers from such attacks by encoding data placed in storage, and varying the encodings used in different storage areas. When the data is needed by a software application, the data is simply decoded in a complementary manner. This prevents storage areas written according to one usage from being used effectively for some other purpose. The method of the invention can be done in a number of ways. For example, a "protector" engine can be placed between a software application and memory, or the function calls in the software application itself, could be amended to include encoding and decoding. Other embodiments and alternatives are also described.

A system and method for an online, peer-to-peer lending platform for microfinance is disclosed. Through the system and method of the present invention, individual and personal lenders across the world can uniquely loan to specific micro-enterprises in many countries and geographic areas in a highly personal and effective manner. This system and method functions as a unique bridge between individual lender and borrower by providing elements and steps for facilitating and processing microfinance institution (MFI) transactions.

An automatic toilet flushing system for use with toilets in either commercial or private dwellings and which comprises a replaceable water tank top or tank lid carrying the major components of the automatic toilet flushing system. In this case, the toilet flushing system is an adaptive system, since it converts a conventional toilet into an automatic flushing toilet. The adaptive system also comprises a pair of infrared light sources and sensors located on forwardly protruding portions of the tank lid. The sensors are located forwardly of the water tank or water chest of the toilet and the timing is adjusted so that raising and lowering of the lid of the toilet seat will not interfere with operation of the sensors. A control circuit is also provided and mounted on the underside of the replaceable water tank cover plate. The circuit is connected to the sensors and operated by batteries so that when a light beam is interrupted for at least a predetermined time period, the control circuit will automatically initiate a flushing operation. The circuit initiates a flushing signal to a solenoid which shifts a connecting rod and which, in turn, is connected to a flapper valve at the lower end of the water chest. Thus, when the light beam is interrupted for the predetermined time period, the control circuit causes the solenoid to operate the rod which opens the flapper valve and thereby causes a flushing operation of the toilet.