35 results about "Fangchinoline" patented technology

The invention discloses a compound algistat which is prepared from berberine, fangchinoline and sanguinarine hydrate. The invention also discloses a preparation method and application of the compound algistat. The compound algistat is an environment-friendly algistat, through the combination and advantage complementary of multiple typical alkaloid compounds, the multiple algae causing algae blooms can be effectively suppressed at the same time, thereby greatly improving the algicidal efficiency. The compound algistat provided by the invention has an effective inhibition rate of 80% to 92% or more within 96h on three kinds of green algae such as microcystis aeruginosa, chlorella pyrenoidosa and scenedesmusobliqnus.

The invention discloses an application of fangchinoline for preparing medicine for treating or preventing HIV. The fangchinoline can dosage-dependently inhibit the copying of HIV-1 under in-vitro condition, and can inhibit the copying of HIV-1 by the percentage of more than 97% under nontoxic concentration on cell. The fangchinoline acts on the later period in a virus copying period, and the action mechanism is different from all the antiviral drugs on the market, and the effect target is new. The fangchinoline is taken as an effective component of traditional Chinese medicinal materials such as Radix Stephaniae Tetrandrae, the source is wide, the fangchinoline has the advantages of safety and low toxicity, and has wide prospect for exploitation of anti-HIV-1 drugs.

The invention provides a radix stephaniae tetrandrae mixture for veterinary use and a preparation method thereof. The sustained-release accessories in the formula can form a biological corrosion framework of medicine molecules; after the medicine is injected into an animal body, the diffusion speed of the medicine can be reduced to realize sustained release, and the administration times for the animal can be reduced while guaranteeing the efficacy; the dregs after distilling cinnamon are decocted again with poria cocos and polyporus umbellatus, so that the leaching amount of active ingredients in the cinnamon, poria cocos and polyporus umbellatus can be increased; and the radix stephaniae tetrandrae is extracted separately, so that the loss of the total amount of alkaloids is reduced, the yield of tetrandrine and fangchinoline is increased, and then the efficacy of the medicine is better. Compared with a radix stephaniae tetrandrae mixture prepared by a common conventional method, by adopting the radix stephaniae tetrandrae mixture for veterinary use, provided by the invention, the medicine taking times by an animal can be reduced, the stress response of the animal is reduced, the content of the active ingredients, namely tetrandrine and fangchinoline, is higher, and the efficacy is better.