1939 results about "Anthocyanidins" patented technology

A composition and method for treating Attention Deficit / Hyperactivity Disorder (ADHD) is provided which can be used both with and without ethical drugs now used to treat ADHD. The composition contains dimethylaminoethanol (DMAE), omega 3-fatty acids, betaine, oligomeric proanthocyanidins (OPC), folic acid, vitamins C, E, B12, B6, B5 and beta-carotene and minerals (calcium, magnesium, zinc and selenium). Ethical drugs such as amphetamines, methylphenidate HCl and pemoline are known to control ADHD, but each has significant side effects when used in their therapeutic dose. When combining the composition with such ethical drugs, the amount of the ethical drug can be lowered below a level which causes undesirable side effects which is an important feature. Preferred compositions contain one or more of lecithin, choline, 5-hydroxytryptophan, tyrosine, Reishi Extract, Kava Extract, Gingko, Ginseng and St. John's Wort.

The invention relates to a composite fresh flower, fruit, vegetable and herb enzyme, and a preparation method and application thereof, and belongs to the technical field of biological medicines. According to the composite fresh flower, fruit, vegetable and herb enzyme, dozens of kinds of common fruits, vegetables, grains, fresh flowers and edible medicine herbaceous plants are adopted as raw materials to comprehensively supplement nutrients, microbes, trace elements and dietary fiber required by bodies; through addition of the fresh flowers, the fresh flower, fruit, vegetable and herb enzyme provided by the invention has the fragrance of the flowers and contains plant anthocyanidin; anthocyanidin substances are plant antioxidants which are high in property; in an enzyme high-acidity solution, anthocyanidin can be well extracted and released, so that the oxidation resistance of the enzyme is improved; most of the edible medicine herbaceous plants have the efficacies of improving immunity and reducing blood fat, blood sugar and blood pressure; through addition of probiotics, polysaccharides and functional ingredients of the herbaceous plants can be completely extracted out, so that the health efficacy of the enzyme is improved. The preparation method for the enzyme is simple, and the problems of pollution and odd flavor generation in the layer-by-layer fermentation process can be effectively solved.

Elevated levels of homocysteine have been implicated as an important risk factor for cardiovascular and other diseases. A composition for decreasing levels of plasma homocysteine and a method for administering the composition are provided, the composition containing dextromethorphan (DM), folic acid and vitamins B6 and B12. The composition provides a synergistic therapeutic effect so that lower amounts of the above ingredients may be employed to minimize any undesirable side effects caused by the use of high levels of a component such as DM. Preferred compositions for cardiovascular diseases further include lecithin, vitamin E, betacarotene, procyanidins / flavonoids, trimethylglycine, garlic oil and minerals. Other compositions for treating glaucoma include bilberry, bioflavonoids and beta-carotene and for treating tardive dyskinesia include an antioxidant such a grape seed extract and pine bark extract, lecithin and oligomeric proanthocyanidins. The compositions may be administered using any suitable means such as orally or intravenous.

A method of delivering dietary supplements, in the form of intact anthocyanins, into the lower gastrointestinal tract of a body for absorption from an aqueous medium comprising: expressing juice from one or more fruits, which fruits include anthocyanins, thereby yielding a juice portion and a pomace portion; concentrating the juice portion to yield a juice concentrate; mixing the juice concentrate with the pomace portion; drying the juice-infused pomace to yield a free-flowing, non-hygroscopic powder formulation to yield the dietary supplement; and orally ingesting the dietary supplement in the form of capsules, tablets, shakes, drinks, energy supplements, energy bars, and the like.

The invention relates to a method for preparing a chitosan and gelatin composite membrane based on anthocyanidin and belongs to the field of intelligent packing materials of food. The method comprises the steps of firstly, obtaining a solution containing appropriate anthocyanidin concentration, and then preparing a chitosan mixed solution and a gelatin solution; mixing the obtained chitosan mixed solution and the gelatin solution, conducting magnetic stirring, and then obtaining a mixed chitosan / gelatin solution; sufficiently mixing the obtained solution containing the appropriate anthocyanidin concentration with the mixed chitosan / gelatin solution, then making an obtained solution flow into a glass plate, conducting natural airing or drying, making the solution to get dry for forming a membrane, and after the membrane is formed, obtaining the composite membrane to be prepared. According to the method, natural pigment is combined with natural high molecular materials such as chitosan and gelatin for the first time, the composite membrane has excellent characteristics of both types of ingredients and is a good green packaging material, the combination of freshness indication and packaging materials is achieved, and compared with a sole indicating card made of biological dye which has toxicity, the composite membrane is safer and can be used as a packaging material for freshness preservation.

Methods of treating skin to counteract the effects of ageing as well as conditions such as acne, rosacea and cellulite along with methods of counteracting specific adverse biochemical reactions in the dermal region are disclosed, wherein the methods comprise (a) providing a skin substrate to be treated; and contacting the skin substrate with a cosmetic preparation comprising at least one oligomeric proanthocyanidin.

The invention relates generally to isolated leucoanthocyanidin reductase LAR polypeptides of the Reductase-Epimerase-Dehydrogenase (RED) protein family, and nucleic acid molecules encoding same and their use in regulating the biosynthesis and accumulation of proanthocyanidins in plants. The invention is further directed to isolated nucleic acid molecules of plants, which encode leucoanthocyanidin reductases of the RED protein family. The isolated polypeptides and nucleic acid molecules of the present invention are useful for modifying the pasture quality of legumes, and, in particular, for producing bloat-safe forage crops, or crops having enhanced nutritional value, enhanced disease resistance or pest resistance, or enhanced malting qualities.

The invention relates to a method for extracting anthocyanin from a cowberry. The method comprises the following steps: taking cowberry fruits, crushing the cowberry fruits, and squeezing the fruits into juice; centrifugating the juice to obtain fruit residues and fruit juice respectively; controlling the temperature of the operation process to less than or equal to 60 DEG C; soaking the obtained fruit residues in a 1 to 10 percent acid-water solution at an operation temperature of between 30 and 50 DEG C; soaking, stirring and extracting the fruit residues for 2 to 3 times, and soaking and stirring the fruit residues for 1.5 to 2 hours every time to obtain an extracting solution; mixing the extracting solution finally obtained and the fruit juice to form a mixed liquor, centrifugating the mixed liquor at a high speed, taking a supernate to carry out ultrafiltration by inorganic film ultrafiltration equipment to obtain a film filtering liquid; purifying resin; controlling the temperature of the operation process to less than or equal to 60 DEG C; adsorbing the film filtering liquid finally obtained to saturate by the resin; washing the resin adsorbed to saturate by water; removing impurities from the resin until washing water shows colorless; desorbing the macroporous absorbent resin by 30 to 50 percent ethanol or methanol, and collecting an effluent liquid; and concentrating and drying the effluent liquid to obtain the anthocyanin.

The invention discloses a skin moisturizing paste and a preparation method thereof and belongs to the technical field of health care food processing. Medical and edible raw materials are selected and combined scientifically; and the skin moisturizing paste is obtained through the steps of raw material impurity removal and cleaning, mixing and decocting, concentration, blending, re-concentration, cooling, filling, sterilization and packaging. The formula of the skin moisturizing paste comprises 20-65 parts by weight of medlar, 4-12 parts by weight of donkey-hide gelatin, 2-7 parts by weight of rose, 20-35 parts by weight of red dates, 0-10 parts by weight of ginseng, 0-15 parts by weight of longan, 0-25 parts by weight of Chinese yam, 0-20 parts by weight of black sesame, 0-15 parts by weight of poria cocos, 0-10 parts by weight of lily and 0-15 parts by weight of hawthorn. The skin moisturizing paste is not added with any food additive and the product is rich in polysaccharide, protein, saponin, anthocyanin, unsaturated fatty acid, mineral element and various vitamins. The skin moisturizing paste is fine, smooth and mellow in taste, and delicious with sour and sweet tastes, and has the effects of nourishing blood and tonifying Qi, strengthening the spleen and stimulating appetite, calming the nerves and improving eyesight, moisturizing the skin and removing spots, whitening the skin and blackening the hair, and delaying aging.

The process of preparing bayberry cyaniding extract includes the following steps: 1. soaking fresh bayberry pulp in 1-10 times water solution of alcohol of 50-95 wt% concentration for over 4 hr; 2. filtering to eliminate alcohol and obtain medicine liquid; 3. regulating pH of the medicine liquid to 1-4 and adsorption in macroporous resin column; washing the column until the effluent becomes no color; 5. eluting with 20-95 wt% concentration water solution of alcohol and collecting the eluted liquid; and 6. filtering to recover alcohol and vacuum drying the eluted liquid at 40-80 deg.c. The present invention also discloses the quality standard and use as food and medicine colorizing agent of the prepared bayberry cyaniding extract.

Cocoa components having enhanced levels of cocoa polyphenols, processes for producing the cocoa components while conserving a significant amount of the cocoa polyphenols, compositions containing the cocoa components or the cocoa polyphenols, and methods of using the cocoa components or the cocoa polyphenols for improving the health of a mammal are described. The cocoa components include partially and fully defatted cocoa solids, cocoa nibs and fractions derived therefrom, cocoa polyphenol extracts, cocoa butter, chocolate liquors, and mixtures thereof. The invention provides processes for extracting fat from cocoa beans and for otherwise processing cocoa beans to yield a cocoa component having conserved concentrations of polyphenols relative to the starting materials.

A synergistic flame retardant composition comprising a phenolic compound comprising condensed tannin, hydrolysable tannin, lignin, cardanol, quercetin, catechin, epicatechin, anthocyanidin, catechol, dopamine, hydroxytyrosol, adrenaline, 4-hydroxyphenylacetic acid, gallic acid, digallic acid, methyl gallate, ellagic acid, phloroglucinol, hexahydroxydiphenic acid, luteic acid, casuarictin, or a combination thereof; and a phosphorus-containing compound comprising a C5-7 carbocyclic polyol substituted with at least one phosphate group.

The invention relates to an anthocyanidin made from Vaccinium uliginosum L. and separation and purification methods thereof, which belong to the technology field of active component extraction and purification and functional food development. The content of anthocyanidin in Vaccinium uliginosum L. is 29.8-40%, wherein the content of malvidin accounts for 4.68-5.48% of the anthocyanidin; and antioxidant activity of the anthocyanidin is as 7.8-15 times as that of Vc. The preparation method includes pre-treating raw material, cold soaking and concentrating, purifying and concentrating, and freeze dying. The ultrasonic and microwave-assisted cold soaking method is employed for separation, and an AB-8 macroporous resin static-dynamic combined absorption purification method is employed. The invention provides an environmental friendly, high-efficiency and low-cost separation and purification technology of anthocyanidin made from Vaccinium uliginosum L., which maintains product bioactivity such as antioxidant property of product and ideal separation effect, establishes the basis for wide utilization of abundant resource of Vaccinium uliginosum L. and industrialized development promotion of a series of Vaccinium uliginosum L. health food, and embodies great economic benefit and social benefit in deep processing of the Vaccinium uliginosum L.

The invention relates to an anti-oxidation health-care wine and its production method, wherein the wine is prepared from the oxidation resistant reactive constituents in grape seed and peel extracted with high grade white spirit or brandy with high ethanol content, the the oxidation resistant reactive constituents in grape seed and peel is proanthocyanidin, resveratrol, polydatin, which can effectively remove excess oxygen-derived free radicals in human bodies.

The invention relates to a blueberry leaves drink with health function based on the blueberry leaves as main material and its making method, wherein the blueberry leaves contents a great amount of flavonoid with more than 40 physiologically activities of reducing blood sugar and blood fat and resisting arrhythmia, the resisting free radical oxidation ability of the blueberry is not compared with the other anti-oxidizing agent, meanwhile there is great amount proanthocyanidins contented in the blueberry with very good health function to the nervous system for children especially for the pregnant woman conspicuously. The making method is characterized by the following: picking the blueberry leaves with more than 90 days growth; using the technique process of washing, immersing, quick freezing, disintegrating, chilling, extracting with vacuum low-temperature, freezing, filtering, allocating, flash sterilizing and germ-free canned. The invention guarantees not to damage the nutrition and effective and active substances in the material almost, which makes the product have certain health function.

The invention discloses a natural food additive which belongs to the technical field of food additives. The natural food additive is characterized by comprising the following substances in percentage by weight: 20%-30% of a red bayberry anthocyanin extractive, 10%-20% of a purple sweet potato anthocyanin extractive, 10%-40% of a mulberry anthocyanin extractive, 10%-50% of an okra pectin and polysaccharide extractive, 10%-20% of a folium ginkgo extractive, 0.0005%-0.0008% of selenium yeast, 2%-10% of seaweed meal, and 5%-10% of ganoderma lucidum spore powder. The natural food additive has strong functions of oxidation resistance, aging resistance, fatigue resistance, invigorating the kidney, strengthening Yang, improving immunity and reducing blood sugar, cholesterol and triglyceride. After the natural food additive is detected, the total anthocyanin content is 15%-36%, the total flavone content is 16%-28% and the total phenolic acid content is 18%-29%.

The present invention is to provide anthocyanin pigments with improved heat-resistance and production thereof, and a method for coloring foods with said anthocyanin pigments and foods colored with said anthocyanin pigments. Heat-resistance in anthocyanin pigments is enhanced by adjusting an aqueous anthocyanin solution to a pH range of 4.0 to 6.5 at a temperature of 40 to 100° C.

The invention discloses the preparation method of carotene, which comprises the following steps: (1) cleaning purple carrot and slicing; (2) extracting and filtering; (3) column chromatography; (4) concentrating and ultra-filtering; (5) micro-encapsulating; (6) spray-drying; and (7) sieving and mixing. The invention also discloses a carotene product, which is purple black powder with a color value equal to or larger than 50 and no peculiar carrot smell, and the carotene product is rich in cyanidin, has resistance to light and heat, and is insensitive to the pH value. Compared with the prior art, the invention has the advantage that the carotene preparation method is provided on the premise that ensures product style and internal quality stability and meets the requirement of consumers and has simple process, mild process condition, short preparation cycle, less equipment investment, recycle use of waste water and reuse of waste as feed additives, and the method is suitable for continuous and large-scale industrial production. The carotene of purple carrot has the advantages of low cost, stable quality and high reliability.

Processes are disclosed for the production of linear and branched procyanidin oligomers having “n” procyanidin monomeric units where n is 2 to 18. The processes include coupling protected, activated monomers with an unprotected monomer to produce a partially protected (4→8) dimer. The dimer is optionally blocked, coupled with an activated protected monomer to produce a partially protected, optionally blocked trimer, and deprotected. The steps can be repeated to produce higher oligomers. Processes are also provided for producing (8→8), (8→6), and (6→6) dimers and doubly branched oligomers. Crystalline 8-bromo tetra-O-benzyl (−)-epicatechin is produced under certain conditions.

The present invention provides a pharmaceutical composition for the treatment of a disordered metabolism syndrome comprising anthocyanin-rich extracts from berries. The present invention further provides a method for treating a disordered metabolism syndrome utilizing anthocyanin-rich extracts from berries.

The invention belongs to the technical field of chemical effective component extraction, and particularly relates to a method for preparing oligomeric proanthocyanidins with uniform polymerization. According to the method, 60-70% ethanol is adopted in extraction, and the pH in the extracting process is controlled to be 4.0-4.4, so that monomer, oligomeric proanthocyanidins and polymer proanthocyanidins can be effectively extracted; macroporous resin is used for adsorbing, and elution is performed according to the principle that proanthocyanidins with different polymerization degrees have different soluble properties in ethanol with different concentrations, so that oligomer products with polymerization degree truly concentrated in 2-4 can be further obtained, and the content of the effective component oligomer in proanthocyanidins can be increased.

A method for the treatment of obesity, diabetes, high cholesterol and related diseases including hyperglycemia, lipid disorders, hyperglyceridemia, dyslipidemia and atherosclerosis in mammals using anthocyanins, anthocyanidins, ursolic acid and / or betulinic acid is described. Compositions adapted for these treatments are also described.

The natural flower health drink, including flower wine, flower honey and flower tea, is prepared with over 100 kinds of wild flowers and through stoving, gamma ray irradiation and soaking in wine, honey or drinking water. The selected wild flowers contain amino acid, natural enzyme, vitamins, cyanidin, aromatic oil and other matters essential for human life activity, some matters with antisenility, antifatigue, anti-cancer and antibacterial functions and trace elements needed by human body.

The invention relates to a stable anthocyanidin prepared by a novel membrane separation technology and a method. The method comprises the following steps: S1, acquiring a raw material extract in a raw material; S2, filtrating the raw material extract by a membrane to obtain a clarification filtrate; S3, performing membrane distillation concentration, drying the clarification filtrate to obtain the stable anthocyanidin; and S4, performing with microencapsulation or liposome-wrapped treatment on the stable anthocyanidin. The preparation method of stable anthocyanidin can obtain the anthocyanidin with characteristics of high color value and stable property, the anthocyanidin comprises more than 60% of cyaniding and Peonidin, has a plurality of human body physiological activities, and can be widely used in various food and nourishment.

The invention relates to a Microorganisms or / and biological enzyme extracting method for plant anthocyanin, belonging to the technical field of biological engineering. The method comprises the following steps of: classifying plants containing anthocyanin for smashing, adsorbing water, freezing the plants, heating the plants for thawing, pressing the plants, filtering for making juice, cracking and degrading the anthocyanin by the microorganisms or / and the biological enzyme cracking anthocyanin glycosidic bond, utilizing an anion active agent for precipitation reaction, degrading the precipitate by the microorganisms, and carrying out precipitation separation and evaporation concentration. Cation anthocyanin with the real content of more than 95%, namely color primitive but not the anthocyanin can be obtained by the technology of the invention. The cation anthocyanin made by the invention does not need human intestinal microorganisms for degrading, and is directly adsorbed and utilizedby a human body or directly goes into human blood. The medical care value of the plant anthocyanin is much higher than that of the anthocyanin.

The invention provides a process for producing oral blueberry powder by vacuum freeze-drying method. The blueberry fruit is cleaned and drained for later use; the drained blueberry fruit is pre-frozen at -20 to -25°C, and the vacuum degree is 10 to 30 mTorr. Keeping constant temperature for 2-20 hours; crushing at -20 to -25° C. to obtain crude blueberry freeze-dried powder. The process route is simplified, and the present invention does not need a long-term high-temperature sublimation process to obtain blueberry freeze-dried powder, which reduces production costs; reduces the heating steps, and further improves the protection of active substances in blueberries; the processing process can avoid high temperature and high humidity, light, and oxidation The influence of factors such as protecting the whole active substance of blueberry; Through comparative measurement the content of anthocyanin contained in the blueberry freeze-dried powder produced by the preparation method of oral blueberry freeze-dried powder provided by the present invention is about 3.0mg / g, conventional method The anthocyanin content contained in the prepared blueberry freeze-dried powder is about 2.4 mg / g, and the anthocyanin content is increased by 15-20%.

The invention relates to the technical field of cell cryopreservation liquids, and in particular relates to a cryopreservation liquid for cultured NK cells and a preparation method of the cryopreservation liquid. The cryopreservation liquid for the cultured NK cells comprises tea polyphenol, a grape seed extract, vitamin C and autoserum. By virtue of adopting the autoserum, pollution of exogenous animal viruses and introduction of exogenous proteins are avoided, and the safety is high; by virtue of adding the tea polyphenol, the grape seed extract (procyanidine) and the vitamin C, cell oxidization can be effectively suppressed, the activity of the cells can be retained, and no harm to a human body is generated; meanwhile, the state of the cells recovered from cryopreservation is basically close to the state before cryopreservation, and the cryopreservation effect is good.

The invention discloses a method for continuously extracting grape seed oil and proanthocyanidin from grape seeds. The method comprises the following steps of: (1) treating grape seeds, and performing crushing, enzymolysis and vacuum drying on the grape seeds; and (2) firstly extracting the grape seed oil by using the supercritical carbon dioxide extraction technology, changing the extracting temperature and the extracting pressure after the grape seed oil is extracted, adding an entrainer, collecting a secondary extract, and obtaining a proanthocyanidin extract through separation and purification. By adopting the method, the total unsaturated fatty acid in the grape seed oil is 80-90 mass percent, and the proanthocyanidin in the proanthocyanidin extract is 90-98 mass percent. By adopting the method, the technologies of vacuum drying, cellulose enzymolysis and supercritical extraction are effectively integrated, so that low-temperature, low-energy, green, efficient and continuous extraction of the active ingredients in the grape seeds is realized. The grape seed oil and the proanthocyanidin extract are widely applied to the fields of medicine, food and health-care food, and have wide prospects.

A disclosed preparation method for a colorful potato pulp juice comprises the following steps: 1) cleaning; 2) homogenate preparation; 3) amylase liquidation; 4) squeezing; 5) enzymolysis; 6)ultrafiltration; 7) concentrating; and 8) filling. The preparation method has the beneficial effects that: according to the provided preparation method for the colorful potato pulp juice, the starch of potatoes is liquidated and hydrolyzed by amylase and further hydrolyzed into monosaccharide or polysaccharose by glucoamylase, and thus the preparation method helps to solve the starch precipitation problem when the juice is prepared from potatoes, and product shelf life is prolonged; the product of the invention has no added additives or flavoring agents, and the nutrition and the mouthfeel of potatoes are furthest reserved; the product of the invention is capable of playing the role of cancer prevention and health care by utilizing anthocyanin in colorful potatoes, reducing cardiovascular disease incidence of middle-aged and elderly people and enhancing immunity; and the preparation method is short in flow and simple in technology, and is capable of realizing industrial production.