35 results about "2-Hexanone" patented technology

It is an object of the present invention to provide an inexpensive and efficient industrial method for obtaining (S)-2-pentanol, (S)-2-hexanol, 1-methylalkyl malonic acid and 3-methyl carboxylic acid at a high optical purity. The present invention provides a method of producing (S)-2-pentanol or (S)-2-hexanol which comprises allowing certain types of microorganisms or transformed cells, a product obtained by treating said microorganisms or cells, a culture solution of said microorganisms or cells, and/or a crude purified product or purified product of a carbonyl reductase fraction obtained from said microorganisms or cells, to act on 2-pentanone or 2-hexanone.

The invention relates to a method for selectively determining residual vinyl acetate in white latex for cigarette through static headspace and gas chromatography mass spectrometry, belonging to the technical field of physical and chemical inspection of materials for the cigarette, and provides a quantitative selected ion determining method through the static headspace and gas chromatography mass spectrometry, aiming at selectively determining the residual vinyl acetate in white latex for the cigarette. A sample of the white latex for the cigarette after static headspace at 80 DEG C for 15 minutes is detected by taking 2-hexanone as an internal standard through HP-INNOWAX column in a GC-MS/SIM (Gas Chromatography Mass Spectrometry/Selected Ion Monitoring) mode, and is quantified through an internal standard method. According to the method for selectively determining the residual vinyl acetate in the white latex for the cigarette through the static headspace gas chromatography mass spectrometry, disclosed by the invention, detection limit, labeling recovery ratio and RSD (Relative Standard Deviation) of the method are respectively 0.63mg/kg, 104-107% and 2.5-4.9%; in addition, the method disclosed by the invention has the characteristics of simpleness, fastness, accuracy, sensitiveness and the like, and is especially suitable for quantitative analysis on the residual vinyl acetate in the white latex for the cigarette.

The present invention discloses a method for simultaneously measuring acetic acid vinyl ester and 6 benzene series substances in water-based adhesive. The method comprises: dispersing samples by using N-N dimethylformamide, quantifying by using double internal standard methods and simultaneously measuring 7 compounds in cigarette water-based adhesive by using a headspace-gas chromatography-mass spectrometer during one sample injection; under adopted chromatographic conditions, chromatographic peaks of benzene, toluene, ethylbenzene, orthoxylen, m-xylene/p-xylene (m-xylene and p-xylene are not separated due to problems of a chromatographic column, but the calculation results are not influenced), and acetic acid vinyl ester target substance as well as two internal standard substances, namely isobutanol and 2-hexanone, are separated well. Results show that the regression equation correlation coefficient of each component reaches 0.999 or more, the quantitative determination limit of the benzene series substances is 0.01-0.02mg/kg, the quantitative determination limit of acetic acid vinyl ester is 0.10mg/kg, the mean relative standard deviation is 1.15%-3.75%, the adding standard recovery is 88.09%-95.44%; the method is fast, accurate, good in repeatability, high in recovery rate, good in practicability, and the like.

The invention discloses a method for measuring content of benzene and benzene series in glycerol triacetate. The method comprises the following steps: preparing a standard working solution, analyzing by gaschromatographic mass spectrometry, drawing a standard curve, calculating a result, etc. After the improvement and optimization, the detection method has the advantages of simplicity, accuracy and sensitivity in operation, high recovery rate, good repeatability and the like. 2-hexanone is used as an interior label, so that by adopting the interior label quantitative detection, errors caused by the preparation process of a sample, different sample loading amounts or instrument precision and the like can be effectively reduced; the adopted chromatographic condition enables the separation degree of six target compounds and interior label chromatographic peaks to be better; moreover, the linear correlation property is better. The detection limit is 0.01 microgram/gram to 0.02 microgram/gram, the quantitative limit is 0.04 microgram/g to 0.06 microgram/gram, the loading recovery rate is 94 percent to 104 percent, and the average relative standard deviation is within 7 percent.

A continuous preparation method of N,N'-bis(1,4-dimethylpentyl)-p-phenylenediamine includes the steps of: 1) performing a reaction to p-nitroaniline or p-phenylenediamine with 5-methyl-2-hexanone and acid in a first reactor to obtain a first material; 2) feeding the first material into a first distillation kettle, and withdrawing 5-methyl-2-hexanone from the top of the distillation kettle and withdrawing a kettle liquid to obtain a second material; 3) feeding the second material into a second reactor, in which palladium, platinum, nickel or the like solids or a supported catalyst thereof is disposed, and feeding hydrogen to perform a reaction to obtain a third reaction solution; and 4) feeding the third reaction solution into a second distillation kettle to perform distillation to obtain the N,N'-bis(1,4-dimethylpentyl)-p-phenylenediamine. The method can avoid a phenomenon that a large amount of alcohol is converted into ketones, which commonly exists in one-step reaction in a kettle reactor a fixed bed reactor, and greatly reduces recovery and treatment cost of the raw material ketone, thereby reducing material consumption and energy consumption.

The invention discloses a method for continuous removal of impurities in cyclohexanone. According to the invention, two adsorbing devices are connected in series; an adsorbent is added into the adsorbing devices for continuous adsorption of impurities in cyclohexanone; and when the total content of impurities discharged by one of the adsorbing devices is greater than 30 ppm, the adsorbing device is subjected to desorption and the other adsorbing device is used for continuous adsorption of impurities in cyclohexanone at the same time. The method provided by the invention effectively removes impurities consisting of 2-heptanone, caproic aldehyde and 2-hexanone in cyclohexanone and allows the total content of the impurities to be less than 300 ppm, which meets requirements of chemical fiber-grade cyclohexanone; and the method can carry out continuous adsorption and desorption, so continuous controllable operation is realized.

This study illustrates a simple and efficient method for the synthesis of tetrabenazine and its intermediates. First, take paraformaldehyde, dimethylamine hydrochloride, and 5-methyl-2-hexanone as raw materials to synthesize the key intermediate 3-dimethylaminomethyl-5-methyl-2-hexanone; secondly, to The crude product is effectively optimized by a simple chemical purification operation to obtain a key intermediate with higher purity; finally, using water as a solvent under the action of a catalyst, the purified key intermediate and 6,7-dimethoxy-3,4 ‑ Dihydroisoquinoline hydrochloride condensation to obtain tetrabenazine crude product, recrystallization can obtain tetrabenazine product, HPLC purity greater than 99.5%. The method uses simple chemical raw materials to obtain key intermediates with high purity through synthesis and purification, thereby further obtaining tetrabenazine products with good purity; the method has easy-to-obtain raw materials, simple operation, no need for special equipment, and high yield , get tetrabenazine with high purity.

The invention discloses a high-toughness packaging material which sequentially comprises an aluminum foil composite film layer, an adhesive layer and a cyclopentadiene film layer from inside to outside. The adhesive layer is prepared by the following steps: adding dipropanediol diacrylate and maleic anhydride into butanone, and reacting under reflux for 50 minutes; adding tetrazole and ethoxylated trimethylolpropane triacrylate, and reacting under reflux for 20 minutes; sequentially adding 1,3,5-triglycidyl-S-triazinyltrione and diethyl phosphite, and reacting under reflux for 2 hours; adding cyanochitosan, polydimethylsiloxane and 2-hexanone, and reacting under reflux for 1.5 hours; and finally, adding rubidium carbonate, continuing reacting for 1 hour to obtain the adhesive layer. By using the reasonable structural design and adhesive layer, the high-toughness packaging material disclosed by the invention has the advantages of favorable mechanical strength, high temperature resistance, favorable packaging protecting property, no pollution and the like, and is convenient to use.

The invention discloses a simple synthetic process of an antidepressant medicine imipramine hydrochloride intermediate. The simple synthetic process includes the following steps: (1) putting 6-amino-2-hexanone, BOC anhydride and DCM into a reaction bottle, and stirring the mixture at a room temperature until the raw materials completely react to form a concentrate; (2) adding AIBN and NBS into theconcentrate, heating the AIBN, NBS and concentrate to reflux, keeping the temperature until the reaction is complete, filtering, leaching a filter cake once with DCM, collecting a filtrate, washing the filtrate one with brine, drying the filtrate with anhydrous sodium sulfate, and reducing the pressure for condensation until the filtrate is dry so as to obtain a crude product; and (3) putting thecrude product into tetrahydrofuran, reducing the temperature to a room temperature, adding 60% sodium hydride soaked and washed twice with methyl tertiary ether into a reaction solution in batches, keeping the temperature until the reaction is complete, pouring the mixture into ice water for extraction twice with methyl tertiary ether, combining organic phases, washing the organic phases with brine, drying the organic phases with anhydrous sodium sulfate, increasing the pressure for condensation, and reducing the pressure for rectification to obtain the final product with the purity being 98.5% and the total yield of the three steps being 61.5%. The synthetic process has the advantages of easily available raw materials, convenient operation and high yield.