55results about How to "Reduce osteoporosis" patented technology

The present invention relates to an active peptide feed addictive, as a mixture of one or more plant protein and animal protein, which is the product of the following steps: fermenting and degrading the mixture through bacillus and the like, controlling the degree of hydrolysis at 20-35%, obtaining a fermentation supernatant after a separation post-processing process, concentrating drying the supernatant or directly adsorbing the supernatant onto the carrier, and then low temperature drying it. Said active peptide feed addictive is capable of obviously depressing development of bacillus coli and salmonella, and can prevention and cure diarrhea caused by bacilli or lienteric diarrhea; can exert its functions at a very low concentration, with a very intense effect; can regulate stomach and intestine bacterium group and promote animals digestion functions; can excite animal immune function, reinforce animal disease resistance against a plurality of epidemic diseases and greatly reduce the morbidity and death rate; can promote animal development and improve the growth velocity; can improve the feed use ratio and reduce production costs. Applications of the microorganism fermentation degradation method provided by the present invention have a low fabricating cost, and the obtained peptides have many kinds and high content, without environment pollutions.

The invented healthy edible salt is prepared by mixing with sodium chloride, various amino acid, peptide substance, vitamin B family, polysaccharide, or chitin, antioxidant, nucleic acid seasoning, potassium chloride, calcium salt, magnesium salt, selenium salt, and potassium iodide. It can effectively prevent various diseases, also can prevent osteoporosis, cancer, diabetes, dysinsulinosis, lithiasis, coronary heart disease, senile dementia, bark farus etc. it also possesses the functions of antisenility, antifatigue, antidepression, improving immune power, promoting growth etc.

The present invention is one health tea for preventing and treating kidney function failure. The fleeceflower root tea includes six products. It has high effect of preventing and treating kidney function failure and has also the functions of reducing blood fat, preventing osteoporosis, and preventing hypertension, apoplexy and coronary heart diseases.

The invention relates to an edible beverage, in particular to a composite carbonated beverage and a preparation method thereof, and the composite carbonated beverage comprises the following raw materials by weight percent: 4-6% of gelatinized rice and / or starch, 6-8% of saccharified malt, 0.08-0.1% of hops or 0.02-0.03% of edible foaming agent, 1-3% of yeast, 0.1-0.15% of one or more of citric acid, malic acid, sodium citrate and tartaric acid, 0.005-0.01% of sodium benzoate or potassium sorbate, 0.1-0.2% of edible essence and the balance of water. The composite carbonated beverage has the advantages of good taste and health care function.

The invention discloses an active polypeptide capable of promoting osteogenesis and inhibiting osteoclast and application of the active polypeptide. N-terminal serine is phosphorylated on the basis ofPTH1-34, and three repeated sequences of glutamic acid or aspartic acid are introduced at a C terminal; the sequence of the polypeptide is shown in SEQ ID NO:1 or SEQ ID NO:2, and the polypeptide hasosteoinductive activity similar to BMP2 and an osteoclast inhibiting effect similar to parathyroid hormones (PTH). Random coils of the polypeptide can be avoided by bonding the C-terminal repeated sequences of the polypeptide to the surface of a calcium phosphate material or a material with a calcium phosphate coating, no addition of organic reagents is needed, and therefore the activity of the polypeptide is protected effectively; furthermore, slow controlled release can be achieved through cleavage of peptide bonds, and long-term intermittent injection of the PTH1-34 can be avoided, so thatthe injection pain of patients is reduced, and effects of osteoblast promotion and osteoporosis inhibition are achieved; a conventional viewpoint that the PTH1-34 cannot be administered locally is changed.

The present invention discloses a surface-drug-loading vertebroplasty dilatation balloon and a preparation method thereof. The surface-drug-loading vertebroplasty dilatation balloon comprises a balloon body, a drug-loading film is attached on surface of the balloon body, the drug-loading film is composed of at least two drug-loading coating layers, and the first drug-loading coating layer directlycontacting the balloon body is formed by electrospinning. The surface of the balloon body is provided with the drug-loading film, and the drug-loading film is composed of a plurality of the drug-loading coating layers, can be retained in body after the balloon is withdrawn, forms an outer shell enclosing bone cement, plays a function of effectively releasing the drugs at desired sites, improves function efficiency of the drugs, and also prevents the bone cement from detaching from positions. The vertebroplasty dilatation balloon has multiple functions, improves postoperative effects of percutaneous vertebroplasty and percutaneous kyphoplasty, and is especially suitable for treatments of osteoporosis and related compression fractures.

The invention discloses a high-strength absorbable bone screw for internal fracture fixation. The bone screw is prepared from a degradable oriented polylactic acid sectional material, wherein the raw material of the oriented polylactic acid sectional material is L-polylactide having a specific rotation of negative155-negative 160 degrees; the sectional material is prepared from L-polylactide sequentially through blank preparing, oriented reinforcing and quenching, the blank preparing method is injection molding, the oriented reinforcing method is forging and pressing or extruding; and the sectional material is manufactured into the bone screw through a turning method, a carving method or a direct molding method. The bone screw has high strength, small attenuation rate of mechanical strength, ensures mechanical support in a bone healing stage and sufficient heating time for injured bones, has good biocompatibility, can be degraded and absorbed, can be used for reducing osteoporosis, and has a remarkable effect on fixing cancellous bone fracture. Under a special condition, the size of the bone screw can be adjusted according to the ankle osteotomy, ankle fracture degree and the growth plate characteristics of ulna.

The present invention discloses a female healthcare food and a preparation method thereof. The female healthcare food comprises the following raw materials in parts by weight: 30-60 parts of lepidium meyenii, 20-55 parts of kudzu vine root and 10-20 parts of Chinese wolfberry fruits. According to the preparation method, biological health activity molecules are extracted through a modern Chinese medicine technology, and the extracted biological healthcare active molecules are added to edible materials and prepared into tablets, granules, hard capsules or oral solutions. The lepidium meyenii, the kudzu vine root and the Chinese wolfberry fruits are processed by a bionanotechnology, such that bioavailability of the healthcare active molecules can be improved, and a female healthcare food can be prepared by a fine processing. The prepared female healthcare food is safe, effective, non-toxic and harmless. The female healthcare food has collaborative action for improving sexual function, improving fertility, regulating endocrine, reducing bone rarefaction caused by ovarian function decline and other related diseases, and improving immune function.

The invention mainly relates to a soft capsule helpful for increasing bone density and a preparation method thereof. The soft capsule helpful for increasing the bone density is characterized by consisting of the following raw materials in parts by weight: 400-550 parts of linseed oil, 10-30 parts of red deer bone superfine powder, 10-30 parts of an astragalus extract, 10-30 parts of bone collagen, 10-30 parts of an angelica extract, 1-3 parts of vitamin D and 10-30 parts of a drynaria rhizome extract. The soft capsule disclosed by the invention, guided by theories of traditional Chinese medicine and based on modern research achievements of the traditional Chinese medicine, is careful in material selection, strict in composition and rational in combination, and is added with natural components capable of improving osteoporosis, so that the composition can tonify Qi and benefit blood, enhance immunity, relieve fatigue, strengthen tendons and bones, remove pathological wind and promote diuresis, regenerate tissue to heal wound, and integrally improve physical function, and circulations of Qi and blood are smooth, and metabolism is normal. Red deer bone functions as strengthening tendons and bones, and regenerating tissue to heal wound; drynaria rhizome can relieve joint pain, and relieve osteoporosis; vitamin D has a function of resisting rachitis, and can promote calcium absorption; astragalus can promote regeneration of injured nerve; angelica functions as replenishing blood and promoting blood circulation, regulating menstruation and relieving pain, and relaxing bowl; and linseed oil has functions of preventing and treating cancers, coronary heart disease, diabetes, prostatic cancer and other diseases. The composition is remarkable in functions of replenishing blood and benefiting blood, and strengthening tendons and bones.

The invention relates to artificial sea cucumbers and a method for preparing the same. The preparation method comprises the following steps of: adding sodium alginate into water, quickly stirring the mixed solution, heating the mixed solution, adding calcium chloride powder into the mixed solution and then slowly and uniformly stirring, adding soybean protein isolates, modified starch, white sugar, monosodium glutamate, yeast extracts and fish flavorings into the mixed solution and then slowly and uniformly stirring to obtain milk white meat materials; preparing milk white glue-like materials according to the same process and raw materials, coloring the milk white glue-like materials by adding caramel pigments, and uniformly stirring the milk white glue-like materials to obtain red brown coarse materials; and mixing the coarse materials and the meat materials in a ratio of 1:1-2, putting the mixture into a die, compacting, steaming, demolding, cooling, packaging and refrigerating to obtain the finished product. The artificial sea cucumbers have the advantages of high content of protein and dietary fiber, red brown color, similar shape and good taste. The preparation method has the advantages of reasonable process, easy preparation, low cost and high operability.

The invention relates to an application of ginsenoside in the preparation of medicine for treating osteoporosis, and the osteoporosis is glucocorticoid-induced osteoporosis. The advantages of the present invention are: the present invention provides a new application of ginsenosides, which broadens the medicinal scope of ginsenosides; At the same time, it can effectively prevent and treat glucocorticoid-induced osteoporosis, and reduce the osteoporosis caused by hormone therapy in patients; Better treatment for patients with steroid-induced osteoporosis.

The invention discloses a method for delaying premature ovarian failure and treating osteoporosis by using umbilical cord blood stem cell infusion combined with autologous peripheral blood stem cells.The method comprises the following steps: step one, preparing umbilical cord blood cytokines, and preparing umbilical cord blood stem cells; step two, initiating autologous peripheral blood stem cells; step three, infusing the umbilical cord blood cytokines into blood to enable the umbilical cord blood cytokines to be combined with the autologous peripheral blood stem cells for treatment; step four, regularly following changes of indicators of curers. According to the method for delaying the premature ovarian failure and treating the osteoporosis by using the umbilical cord blood stem cell infusion combined with the autologous peripheral blood stem cells, the autologous stem cells have no immune rejection and can survive for a long time, but the activity of the cells is insufficient; theliving environment of the autologous stem cells is improved by the method of inputting cytokines, the combined use of the two enhances the complementary advantages, no side effect exists during a process of delaying the premature ovarian failure and treating the osteoporosis, and a damaged tissue is repaired by inputting the umbilical cord blood cytokines and the autologous peripheral blood stem cells to restore organ functions to delay the premature ovarian failure and treat the osteoporosis.

The invention discloses a medicament composition for supplementing calcium, belonging to the field of medical technology. The medicament composition comprises the following components: 180-220mg of collagen albumen powder, 460-530mg of calcium carbonate, 400-500mg of starch and 40-60mg of dextrin. The medicament composition has better effect on treating calcium deficiency for persons at different ages, and has functions of delaying osteoporosis, accelerating bone healing, keeping bone tenacity and preventing loss of calcium.

The invention belongs to the technical field of solid beverages, and particularly relates to a high-protein probiotic solid beverage. The high-protein probiotic solid beverage comprises the following component raw materials in parts by weight: 65-70 parts of soybean protein isolate, 15-20 parts of whole milk powder, 15-26 parts of resistant dextrin, 15-20 parts of maltooligosaccharide powder, 10 parts of oat crisp grains, 15-25 parts of nonfat dry milk powder, 10-15 parts of whey protein and 10-15 parts of fish collagen peptide powder. The high-protein probiotic solid beverage disclosed by the invention has the beneficial effects that the soybean protein isolate is used as a main material, so that the intake of cholesterol and saturated fat is reduced, and besides, the balance of nutrient intake is also achieved; the soybean protein can prevent urinary calcium loss, promote bone health, reduce the probability of suffering from osteoporosis, and effectively reduce the content of total cholesterol and low-density lipoprotein cholesterol in blood of human bodies, so that the risk of suffering from heart diseases is reduced; and besides, original nutrition inhibiting factors namely trypsin inhibitors in soybeans are removed from the soybean protein isolate powder, so that people do not need to worry about adverse reactions of indigestion, gaseous distention and the like.

The invention discloses a double-peptide solid beverage. The double-peptide solid beverage is used as an anti-aging skin repairing solution and comprises the following raw materials in percent by mass: 70% of bovine bone peptide, 10% of sea cucumber peptide, 15% of ginseng peptide and 5% of edible essence. The double-peptide solid beverage has the advantages as follows: the double-peptide solid beverage can significantly improve the immunity of a body, effectively improve cardiovascular and cerebrovascular systems, eliminate joint pain, delay osteoporosis and nourish hair and nails.

The invention discloses a preparation method of a compound-type high-calcium protein powder preparation. According to the invention, the method includes the following steps: adopting disodium hydrogen phosphate-citric acid buffer solution as an extracting agent, simulating the pH of human stomachs to extract the nutritional components of fish bones and performing pulsed electric field treatment to fully extract the soluble calcium of the fish bones; and then chelating the soluble calcium with soy protein peptides to prepare soy protein peptide chelated calcium and performing combination with the insoluble and soluble calcium of a food nutrient-intensifying agent. The prepared protein powder improves the absorption of the soluble calcium of the fish bones for human bodies, effectively promotes bone health and reduces the chance of suffering from osteoporosis and the quality and eating taste of products are also improved.

The invention provides a follicular granulosa cell anti-senescence technology, wherein animal follicular granulosa cells are employed for transplantation, the process comprises the steps of (1) placing ovarium of pig or sheep into curling, (2) culturing the follicular granulose cells, shearing ovarium into small blocks, carrying out grinding, sieving, slaking, purifying and placing into culture bottle, then charging QM-1640 culture liquid containing AB-serum, loading into CO2 incubator for culturing, (3) the application method comprises injecting the ovarian follicle granular cells into human body muscle or waist subarachnoid cavity.

The invention discloses a compound preparation containing glucosamine, chondroitin, collagen and curcumin and a preparation method of the compound preparation. The compound preparation is prepared from components in percentage by weight as follows: 15%-40% of glucosamine hydrochloride granules, 15%-40% of chondroitin sulfate granules, 5%-20% of calcium citrate granules, 2%-8% of a coating premix,5%-15% of microcrystalline cellulose, 0-5% of crosslinked sodium carboxymethyl cellulose, 0-5% of silicon dioxide, 0-5% of crospovidone, 0-2% of magnesium stearate, 5%-20% of collagen and 2%-12% of curcumin. The preparation method comprises the following steps: (1) wet granulation of glucosamine hydrochloride; (2) dry granulation of chondroitin sulfate; (3) mixing and pressing for tablet formation; (4) coating. The compound preparation is reasonable in matching and balanced in proportion and can improve osteoporosis and arthritis and promote bone health.

Belonging to the technical field of medicine application, the invention discloses pharmaceutical application of caffeic acid 3, 4-dihydroxyl phenethylester. A prevention and / or treatment medicine prepared from the caffeic acid 3, 4-dihydroxyl phenethylester (CADPE) can be used for inhibiting osteoclast differentiation, inhibiting an osteoclast bone erosion function, promoting osteoblast differentiation, and promoting an osteoblast bone formation function. The medicine can be used for preventing and / or treating osteoclast activity abnormality caused diseases, which include osteoporosis, rheumatoid arthritis, periodontitis, tooth loss, Paget's disease, rickets, osteoclastoma, myeloma bone disease and cancer bone metastasis caused bone destruction, etc.

The invention relates to the field of health foods and particularly relates to a capsule for increasing bone density and a preparation method of the capsule. The capsule for increasing bone density is prepared from the following raw materials in parts by weight: 130-150 parts of D-glucosamine hydrochloride, 100-120 parts of olive juice freeze-dried powder, 40-80 parts of chitosan oligosaccharide, 150-170 parts of oyster calcium and 0.1-0.5 part of vitamin D3. The capsule provided by the invention is scientific in formula, is matched and shared and realizes the function of eliminating arthralgia, strengthening tendons and bones, improving osteoporosis, repairingcartilago articularis and increasing bone density by various paths and multiple layers.

The invention provides use of crataegolic acid and derivatives thereof in preparation of medicines for inhibiting osteoclast differentiation and function and osteoclast activity associated diseases. The invention also provides the use of a composition, which contains an effective dose of crataegolic acid of formula (I) and derivatives thereof and pharmaceutically acceptable ingredients, in the preparation of medicines for inhibiting osteoclast differentiation and function.

The present invention belongs to the field of animal feeds, and discloses a microemulsion preparation for breeding pigs. Each 1000 parts by weight of the microemulsion preparation comprises 11-15 parts by weight of an emulsifier, 2-4 parts by weight of a co-emulsifier, 1-2 parts by weight of vitamin A acetate, 1-2 parts by weight of cod liver oil, 0.5-1 part by weight of folic acid, 3-4 parts by weight of vitamin E, and the balance of a traditional Chinese medicine extract. Each 100 parts by weight of the traditional Chinese medicine extract is obtained by extracting 200-300 parts of motherwort herb, 150-200 parts of cassia twigs, 10-30 parts of cape jasmine fruits and 10-20 parts of liquorice in a percolation method. The emulsifier consists of 10-20% by weight of C14-C16 alkyl polyglucoside and 80-90% by weight of Tween 80. The co-emulsifier is ethanol. At the same time, the invention also discloses a preparation method of the preparation. The preparation has the advantages of reducing estrus returning rate, improving the survival rate of piglets, promoting the growth of piglets and reducing the morbidity of postpartum sows.

The invention discloses a lotus craft beer brewing process and flow, and belongs to the technical field of beer. Lotus craft beer is brewed from Australia malt, burnt malt, aqueous extract of folium forsythia, aqueous extract of honeysuckle flower, aqueous extract of semen armeniacae amarum, aqueous extract of houttuyniae herba, aqueous extract of liquorice root, aqueous extract of lophatherum herb, aqueous extract of chicory, purified water and additives by mixing and sequentially carrying out saccharification, fermentation, filtration and sterilization. According to the invention, on the basis of using traditional beer raw materials including water, malt and hops, the folium forsythia (extract), the honeysuckle flower (extract), the semen armeniacae amarum (extract), the houttuyniae herba (extract), the liquorice root (extract), the lophatherum herb (extract) and the chicory (extract) are added in different production processes; intrinsic active substances of the seven traditional Chinese medicines are sufficiently played under the action of yeast biological fermentation; and the aims of invigorating stomach, tonifying qi, eliminating carbuncle and eliminating stagnation are fulfilled.

The invention discloses an anti-aging traditional Chinese medicine composition to prevent and treat osteoporosis, which is prepared with marine life waste, oyster meat, golden camellia leaves, honeysuckle flowers or wild honeysuckle flowers, chrysanthemum flower, sophora flower, immature flower of bitter citrus, jasmine flower, root of kudzu vine and the like. The anti-aging traditional Chinese medicine composition has the effects, such as tonifying kidney and benefiting spleen, nourishing yin and supporting yang, calming the heart and tranquilizing the mind, clearing liver to improve eyesight, invigorating pulse-beat to discharge toxins, and strengthening body resistance and eliminating evil, and is applicable to moistening skin and maintaining beauty, strengthening the body and tonifyingdeficiency, and delaying aging. The anti-aging traditional Chinese medicine composition is also suitable for preventing and treating sexual debility, gastrointestinal hypofunction, osteoporosis and the like. The anti-aging traditional Chinese medicine composition has mild action and high safety and stability, and causes no toxic and side effects or adverse response to human. The anti-aging traditional Chinese medicine composition can be made into capsules, granules, tablets, oral solutions, functional health drinks and the like, is suitable for patients with different conditions to carry andadminister, and is especially good for maintaining beauty, bone and life and preventing and treating senile diseases, thereby positively maintaining people's health.

As an astronaut is not under the pressure of a gravity force in a space capsule, the weight of a human body is almost zero, functions such as walking muscles temporarily degrades to a certain degree to generate osteoporosis after a long time, the astronaut needs people to hold after returning to the earth and gets out of the space capsule and must condition the body. A joint gravity force boosterA, a waist joint fixing frame 4 and thigh fixing wrapping sheets 9 in a health care aerospace apparel are mounted on a spacesuit. By adopting a one-way rotating internal ratchet wheel seat 23, a friction sheet 20 structure needs to be rotated to apply a force during lifting legs; however, in the case of weightlessness in the space capsule, the force of lifting thighs is just weight compensation ofthe gravity force booster A to the thighs; liners such as fabrics are all additionally mounted in mounting parts of the wear so that the health care aerospace apparel is comfortable to wear; as a gravity force tension layer 2 is mounted in the health care aerospace apparel, rhythmic exercising can be generated once a person moves or stands so that segmented columns and muscles of the whole body suffer a rhythmic pressure; when the person wears a inflating stretch apparel or a knitted stretch wear matched with the health care aerospace apparel, the health care aerospace apparel can apply different elastic pressures with different forces to the body according to different parts of the body, and therefore, the muscles which are light as a feather do not expand in the case of weightlessness;and as the elasticity of the apparel and the elasticity of trousers are not as same as each other, the blood supplies to legs and feet can be increased, and the osteoporosis can also be reduced.

The invention discloses a preparation method of hairtail active extract for repairing bone joints; the preparation method comprises the steps of enzyme complex hydrolysis, multistage membrane filtration, nanofiltration, HPLC (high-performance liquid chromatography) eluting and lyophilizing; the step of enzyme complex hydrolysis includes enzymatically hydrolyzing hairtail flesh homogenate via Bacillus marinus alkali-producing proteinase and Porphyra yezoensis proteinase, and performing ultrasonic-assisted enzymatic hydrolysis. The preparation method has the advantages that marine organism proteins are greatly differed from terrestrial life proteins in both amino acid composition and amino acid sequence and hairtail proteins can be enzymatically hydrolyzed via the Bacillus marinus alkali-producing proteinase and Porphyra yezoensis proteinase to obtain mass active peptides; the obtained hairtail active extract can promote the generation of cartilage cells, joint synovial fluid can be massively induced and supplemented, the generation of collagen matrix can be effectively promoted, regeneration of connective tissue cells is stimulated, and the reconstruction and recovery of soft tissues are accelerated accordingly.

The invention relates to the technical field of beer, and discloses beer having effects of nourishing yin and tonifying kidney and a preparation process of the beer. The beer having effects of nourishing yin and tonifying kidney is prepared by mixing Australia malt with burnt malt, mulberry fruit powder, lotus seed powder, oyster peptide, a raspberry extract, a wolfberry fruit extract, purified water and an additive; and performing saccharifying, performing fermenting, performing filtering and performing sterilizing to brew. The beer having effects of nourishing yin and tonifying kidney is prepared from the following components in parts by weight: 535 parts of the Australia malt, 15 parts of the burnt malt, 6 parts of the mulberry fruit powder, 5 parts of the lotus seed powder, 1-3 parts of the oyster peptide, 3-5 parts of the raspberry extract and 4-6 parts of the wolfberry fruit extract. On the basis of using traditional beer raw materials of water, malt and hops, in different production processes, according to compatibility of monarch, minister, assistant and guide of the traditional Chinese medicines, intrinsic active substances of the traditional Chinese medicines of all the components are sufficiently exerted under the action of biological fermentation of yeast, and the purpose of the beer having effects of nourishing yin and tonifying kidney is achieved.

The invented healthy edible salt is prepared by mixing with sodium chloride, various amino acid, peptide substance, vitamin B family, polysaccharide, or chitin, antioxidant, nucleic acid seasoning, potassium chloride, calcium salt, magnesium salt, selenium salt, and potassium iodide. It can effectively prevent various diseases, also can prevent osteoporosis, cancer, diabetes, dysinsulinosis, lithiasis, coronary heart disease, senile dementia, bark farus etc. it also possesses the functions of antisenility, antifatigue, antidepression, improving immune power, promoting growth etc.