The invention relates to application of a fluorine-doped perovskite-type membrane in oxygen separation. A membrane material is perovskite crystal form of oxyfluoride shown by a general formula AxA'1-xByB'1-yO3-gamma F delta, wherein the gamma represents the number of oxygen lattice defects, the A and the A' are any one of the elements Ce, Pr, Nd, Ca, Sr, Ba and La, the B and the B' are any one of the elements Co, Fe, Nb, Ta, Mo, W, Sc, Ti, Zr, Sn and Sb, 0 <= x <= 1, 0 <= y <= 1, and 0 <= gamma <= 1. The material is prepared by adopting a solid-phase reaction method, a uniaxial pressure method, a plastic extrusion method or a phase transformation method is adopted in the membrane forming process, the oxygen permeation capacity of the oxygen permeation membrane material can be remarkably improved by doping nonmetal fluorine, the high stability of the material at oxygen partial pressure is kept, and the fluorine-doped perovskite-type membrane further has excellent medium and low temperature performances, is suitable for long-term operation of low-temperature oxygen separation and meets the demand of industrial application.