14536results about "Force measurement" patented technology

The present invention relates to a non-invasive device for measuring physiological processes. More particularly, it concerns a device that can be applied externally to the body of an animal or human to detect and quantify displacement, force, motion, vibration and acoustic effects resulting from internal biological functions. Specifically, an inexpensive device is disclosed that is compact, light, portable and comfortable, and operates satisfactorily even with imprecise location on the body, ambient noise, motion and light.

This invention relates generally to the field of moiety or molecule manipulation in a chip format. In particular, the invention provides a method for manipulating a moiety in a microfluidic application, which method comprises: a) coupling a moiety to be manipulated onto surface of a binding partner of said moiety to form a moiety-binding partner complex; and b) manipulating said moiety-binding partner complex with a physical force in a chip format, wherein said manipulation is effected through a combination of a structure that is external to said chip and a structure that is built-in in said chip, thereby said moiety is manipulated.

An electrophoretic medium comprises a liquid and at least one particle disposed within the liquid and capable of moving therethrough on application of an electric field to the medium. The medium further comprises a free radical scavenger selected from the group consisting of (a) stable free radicals; and (b) polymeric free radical scavengers comprising a plurality of free radical scavenging groups attached to a polymeric chain. The medium is desirably encapsulated.

The present invention relates to droplet-based particle sorting. According to one embodiment, a droplet microactuator is provided and includes: (a) a suspension of particles; and (b) electrodes arranged for conducting droplet operations using droplets comprising particles. A method of transporting a particle is also provided, wherein the method includes providing a droplet comprising the particle and transporting the droplet on a droplet microactuator.

A method for the detection of analytes using resonant mass sensors or sensor arrays comprises frequency encoding each sensor element, acquiring a time-domain resonance signal from the sensor or sensor array as it is exposed to analyte, detecting change in the frequency or resonant properties of each sensor element using a Fourier transform or other spectral analysis method, and classifying, identifying, and/or quantifying analyte using an appropriate data analysis procedure. Frequency encoded sensors or sensor arrays comprise sensor elements with frequency domain resonance signals that can be uniquely identified under a defined range of operating conditions. Frequency encoding can be realized either by fabricating individual sensor elements with unique resonant frequencies or by tuning or modifying identical resonant devices to unique frequencies by adding or removing mass from individual sensor elements. The array of sensor elements comprises multiple resonant structures that may have identical or unique sensing layers. The sensing layers influence the sensor elements' response to analyte. Time-domain signal is acquired, typically in a single data acquisition channel, and typically using either (1) a pulsed excitation followed by acquisition of the free oscillatory decay of the entire array or (2) a rapid scan acquisition of signal from the entire array in a direct or heterodyne configuration. Spectrum analysis of the time domain data is typically accomplished with Fourier transform analysis. The methods and sensor arrays of the invention enable rapid and sensitive analyte detection, classification and/or identification of complex mixtures and unknown compounds, and quantification of known analytes, using sensor element design and signal detection hardware that are robust, simple and low cost.

A capacitive touch sensor system and method incorporating an interpolated sensor array is disclosed. The system and method utilize a touch sensor array (TSA) configured to detect proximity/contact/pressure (PCP) via a variable impedance array (VIA) electrically coupling interlinked impedance columns (IIC) coupled to an array column driver (ACD), and interlinked impedance rows (IIR) coupled to an array row sensor (ARS). The ACD is configured to select the IIC based on a column switching register (CSR) and electrically drive the IIC using a column driving source (CDS). The VIA conveys current from the driven IIC to the IIC sensed by the ARS. The ARS selects the IIR within the TSA and electrically senses the IIR state based on a row switching register (RSR). Interpolation of ARS sensed current/voltage allows accurate detection of TSA PCP and/or spatial location.

A device for generating droplets includes a substrate comprising a reservoir site configured to hold a liquid and including a first electrode, a droplet creation site including a second electrode, and droplet separation site disposed between the reservoir site and the droplet creation site and containing an electrode. The device includes control circuitry operatively coupled to the first, second, and third electrodes. The control circuitry is configured to measure the fluid volume on the electrodes and independently adjust an applied voltage to increase/decrease the quantity of fluid. The device can move fluid onto the creation site or back onto to the reservoir site. When the fluid volume is at the desired value or range, a driving voltage is delivered to the first and second electrodes to form a new droplet. The device may generate droplets having a uniform or user-defined size smaller than the electrode.

Modular fluidic microchips, systems integrating such microchips, and associated preparative and analytical methods are presented.

A multidrop network of multichannel, addressable sensing modules (ASM's), to be embedded within a composite structure, remotely powered, and interrogated by a personal computer through a non-contacting inductive link. Each ASM contains a microprocessor with non-volatile memory, multiplexer, programmable gain and filter instrumentation amplifier, and sigma delta analog to digital converter (all housed in two thin surface mount packages). An embedded mothernode includes circuitry for power and data reception (into the structure), and data transmission (back out of the structure). The external interrogation system communicates into the network of ASM's by modulating the AC waveform that delivers power to the embedded electronics. Once addressed, each ASM powers up its programmable (gain & filter) sensing channels (3 full differential or 5 pseudo differential) and data conversion elements. Sensed data are pulse code modulated, including error checking, which serially modulate an RF carrier for wireless transmission out of the composite to the interrogating computer. These advanced, micro-miniature sensing networks may be applied to a wide variety of military, medical, & civil structures.

A sensor system (30) has a sensor module (10) and a receiver module (45). The sensor module (10) functions as a wireless data collection device and has a flexible thin sheet of silicon (60, 65, 70) comprising circuitry (71, 72, 73), a flexible power source (105), and a flexible support substrate (55). The silicon, power source, and flexible support substrate are integrated as layers of the sensor module (10). The layers are placed together in the form of an adhesive bandage (10). A plurality of electrodes (80) are connected to the sensor module (10) and protrude from the flexible substrate (55) for contacting the skin of a subject body (20). The receiver module (45) includes one of an RF receiver with a wireless port for continuously receiving data (40), or a physical I/O port (87) to which the sensor module (10) can be physically connected for downloading stored data from the sensor module (10).

The present invention describes methods and systems for extracting, capturing, reducing, storing, sequestering, or disposing of carbon dioxide (CO₂), particularly from the air. The CO₂ extraction methods and systems involve the use of chemical processes, mineral sequestration, and solid and liquid sorbents. Methods are also described for extracting and/or capturing CO₂ via condensation on solid surfaces at low temperature.

A shape sensing system to determine the position and orientation of one link with respect to another link in a kinematic chain. An optical fiber is coupled to two or more links in a kinematic chain. A shape sensing segment is defined to start at a proximal link and to end at a distal link, crossing one or more joints. A reference frame is defined at the start of the shape sensing segment. As the joints move, an interrogator senses strain in the shape sensing segment. The sensed strain is used to output a Cartesian position and orientation of the end of the shape sensing segment with respect to the reference frame defined at the start of the shape sensing segment. The pose of the kinematic chain is determined from the Cartesian positions and orientations of one or more shape sensing segments defined for the kinematic chain and from an a priori model and constraints of the kinematic chain.

An article of footwear includes an upper member and a sole structure, with a sensor system connected to the sole structure. The sensor system includes a plurality of sensors that are configured for detecting forces exerted by a user's foot on the sensor. Each sensor includes two electrodes that are in communication with a force sensitive resistive material. Additionally, the sensor system may be provided on an insert that may form a sole member of the article of footwear. The insert may include an airflow system that includes one or more air chambers in communication with one or more air reservoirs through air passages extending therebetween. The insert may also have a multi-layered structure, with the airflow system provided between the layers.

A series of microactuators for manipulating small quantities of liquids, and methods of using these for manipulating liquids, are disclosed. The microactuators are based on the phenomenon of electrowetting and contain no moving parts. The force acting on the liquid is a potential-dependent gradient of adhesion energy between the liquid and a solid insulating surface.

The device comprises a rigid former reproducing the volume of a portion of the body and suitable for receiving the compressive orthosis. The former (10) incorporates a plurality of sensors (22) distributed over various points of the former and configured in such a manner as to avoid significantly modifying the surface profile of the former, the sensors essentially measuring the pressure applied locally on the former by the orthosis at the location of the sensor and perpendicularly to the surface of the former. Advantageously, at the location of the measurement point, each sensor comprises a thin wall capable of being subjected to microdeformation under the effect of the pressure applied by the orthosis, and means such as a strain gauge bridge, for example. The thin wall can constitute a portion of a support pellet which is fitted to the former in such a manner that its outside surface, which includes the thin wall, is flush with the outside surface of the former.