41 results about "Tritirachium album" patented technology

The invention provides an antibacterial ceramic cutting tool which is prepared from a ceramic material and an antibacterial active material. Based on the total weight of the ceramic material and the antibacterial active material, the addition of the antibacterial active material is 3-10wt% and the balance is the ceramic material. The ceramic material comprises one or more than one of zirconium oxide, aluminum oxide, silicon nitride, titanium carbide or titanium nitride. The antibacterial active material comprises silver oxide, copper oxide, titanium oxide, silicon oxide, aluminum oxide, alkali metal oxide, alkaline earth metal oxide and inevitable impurities. The grain size of the antibacterial active material is 10-100nm. Meanwhile, the invention further provides a preparation method of the antibacterial ceramic cutting tool. The antibacterial ceramic cutting tool provided by the invention is good in antibacterial and bacteriostatic effect, and particularly has a good capability of resisting and inhibiting staphylococcus aureus and tritirachium album.

The invention discloses a curcumin antibacterial fiber and a preparation method thereof. The curcumin antibacterial fiber contains cactus extract serving as a raw material; and the antibacterial effect of a fiber product on escherichia coli, golden glucose bacteria or tritirachium album reaches over 95 percent. According to the method for preparing the curcumin antibacterial fiber, the curcumin antibacterial fiber is obtained by wet spinning after plant antibacterial serum is mixed with a viscose solution, wherein the plant antibacterial serum with solid content of 15 to 20 percent is obtained by emulsifying the cactus extract in water, and the mass ratio of the plant antibacterial serum to the viscose solution is (1-10): 100. The curcumin antibacterial fiber is environment-friendly, and the antibacterial effect of the curcumin antibacterial fiber is more than or equal to 95 percent.

The invention provides a textile material consisting of the following components by mass: 50%-70% of cotton fiber, 10%-20% of bamboo carbon fiber, 5%-12% of chitosan fiber, 5%-15% of terylene and 7%-12% of acrylic fiber. The textile material has the following benefits that: the fiber material has the functions of warm keeping, moisture absorption and air ventilation; the chitosan fiber has biological activity and biocompatibility and can effectively restrain golden yellow staphylococcus, colon bacillus and tritirachium album and the like; and the bamboo carbon fiber has the function of moisture absorption.

The invention discloses a bacteriostatic agent for sterilization and disinfection, skin mucosa disinfection fluid and a preparation method thereof. The bacteriostatic agent is mainly prepared from honeysuckle, bo-chrysanthemum, mint, dandelion, folium isatidis and chlorhexidine acetate according to a certain weight ratio. The bacteriostatic agent is prepared by a basic formula of the Central Treasury Canon written by Huatuo according to a research and is a high-tech natural disinfection product refined by combining the modern traditional Chinese medicinal science practice and the modern traditional Chinese medicinal technology; the disinfection fluid and the bacteriostatic agent are prepared according to the reliable practice and the theory basis and can effectively kill various fungi, mildew, tritirachium album, staphylococcus aureus, escherichia coli, various types of viruses and conventional pathogenic bacteria.

The invention relates to the field of microbial disease control and in particular relates to a probiotic with bacteriostatic ability. The probiotic is Enterobacter ludwigii-PC88, is collected in China General Microbiological Culture Collection Center (CGMCC) on June 24, 2013, and has a collection number of CGMCC No.7814. The probiotic is separated from intestinal tracts of healthy flounders. The pure culture of the probiotic has relatively strong inhibitory effects on aquatic pathogens such as vibrio splendidus, vibrio harveyi, vibrio parahaemolyticus, pseudomonas aeruginosa and vibrio anguillarum, also can inhibit growth of known human pathogens such as tritirachium album, staphylococcus aureus and klebsiella pneumoniae, and has resistance to ampicillin. The pure culture or composition of the probiotic can be used for control of aquaculture diseases and development of novel antibacterial materials, and has good application prospects.

The invention relates to the field of microbial disease control and in particular relates to a probiotic separated from intestinal tracts of turbots and an application thereof. The probiotic is Leclercia adecarboxylata P115, is collected in China General Microbiological Culture Collection Center (CGMCC) on June 24, 2013, and has a collection number of CGMCCNo.7813. The probiotic is separated from the intestinal tracts of healthy turbots. The probiotic and the pure culture thereof have obvious bacteriostatic effects on tritirachium album, klebsiella pneumoniae, staphylococcus aureus, vibrio parahaemolyticus, vibrio harveyi and vibrio anguillarum. The pure culture or composition of the probiotic can be used for control of aquaculture diseases and development of novel antibacterial materials, and has good application prospects.

The invention discloses herba epimedii antibacterial essential oil which is prepared from the following components in percentage by weight: 0.1-0.2% of compounded essential oil, 0.1-0.5% of eucalyptusglobulus oil, 0.5-2% of ginger root oil, 0.3-1.0% of rosemary leaf oil, 0.1-0.5% of cinnamon oil, 0.5-1.5% of basil oil, 0.5-1% of crocus sativus, 1.4-2.5% of pelargonium roseum ait oil, 1-3% of camellia-seed oil, 0.5-1.0% of clove oil, 0.1-0.3% of borneol, 50% of sweet almond oil, 0.1-0.3% of p-chloro-dimethylphenol, 0.01-0.2% of butylated hydroxytoluene and the balance of olive oil, wherein thecompounded essential oil is prepared by the following steps: respectively weighing truffle, centella asiatica, herba epimedii and honeysuckle according to a weight ratio of 1:3:3:3, crushing into granules of which the diameter is 3-8mm, adding 10 times of water, and soaking for 30-60 minutes at a normal temperature. The invention relates to the technical field of medicine preparations. The herbaepimedii antibacterial essential oil has inhibition functions on various fungi, mold, tritirachium album, staphylococcus aureus, escherichia coli, various viruses and common pathogenic bacteria.

The invention relates to the field of nursing products, in particular to a micro-ecological antibacterial liquid, which is prepared from the following raw material components, including 8-12% of inactivated probiotics, 0.1-1% of lactic acid, 15-25% of a plant extract, and the balance of pure water according to mass concentration. The antibacterial liquid can kill bacteria quickly, the bactericidalrate against Escherichia coli, Tritirachium album and Staphylococcus aureus is over 90%, the plant extract, inactivated probiotics and lactic acid can quickly balance female reproductive micro-ecology, especially the reproductive micro-ecology of patients with gynecological diseases. The invention also provides a preparation method of the micro-ecological antibacterial liquid.

The invention discloses an antifungal compound extract, a preparation and a preparation method of the extract. The antifungal compound extract comprises the following components in parts by weight: 1-3 parts of a gallnut extract, 1-3 parts of a fructus cnidii extract, 1-3 parts of a pogostemon cablin extract, 0.5-1.5 parts of a galangal extract, 0.5-1.5 parts of a radix sophorae flavescentis extract, 0.5-1.5 parts of a radix clematidis extract, 0.5-1.5 parts of a fructus kochiae extract and 0-80 parts of an ethanol-water solution. The components of the antifungal compound extract are extractedby adopting a hot reflux extraction method; and ethanol-separated and purified liquid obtained after separation and purification of macroporous adsorption resin has an obvious effect of resisting trichophyton rubrum and tritirachium album and can be used for preventing and treating fungal infection of human skin, hair and nails. Meanwhile, plant extracts are compounded to be prepared into powderygranules, the solubility is increased, the state is good, the medicine curative effect is long, and the medication form is convenient.

The invention relates to a production technology for fermentatively producing proteinase K by utilizing fungi microorganisms. The production technology comprises the following steps of: using tritirachium album limber (Tritirachium Album Limber) as an original strain; mutagenizing by means of 60Go Gamma rays, and also mutagenizing by a protoplast in the presence of ultraviolet rays; introducing a special culture medium; and carrying out submerged fermentation to produce the proteinase K. Under the culture conditions that the culture temperature is 22 to 28 DEG C, the pH (Potential Of Hydrogen) of fermentation liquor is maintained within the range of 5.5 to 6.0, and a fermentation tank is at the speed of stirring of 250 to 500rev / min, the output of the proteinase K is greatly increased; and the production technology is suitable for being applied to industrial production. Compared with the prior art, the production technology for fermentatively producing the proteinase K by utilizing the fungi microorganisms, provided by the invention, can be used for filling the gap in production technology of the proteinase K of domestic, greatly increasing the biological expression quantity, and decreasing the production cost at the same time, and therefore, the market competitiveness of products can be greatly improved.

The invention belongs to the technical field of research and development on medical products. The invention applies for the protection of a method for extracting components having antibacterial activity from fruit of pedunculate herpetospermum which is a Tibetan medicine. The method comprises: extracting coarse extract from the dried and crushed fruit of pedunculate herpetospermum by using a solvent and a solid-liquid extraction method, and concentrating the coarse extract to obtain extract; obtaining extract with obvious antibacterial effect by degreasing, concentrating and extracting; and further separating the extract by silica gel column chromatography and obtaining the effective extract components. The product of the invention has different inhibition effects on golden staphylococcus, tritirachium album, bacillus subtilis and salmonella, can be developed as a natural antibacterial to be used in medical industry and can be prepared into antibacterial tablets, granules, capsules, injection, skin external preparations and other formulations. Thus, a new field of the development of the pedunculate herpetospermum fruit Tibetan medicine is opened.

The invention relates to a microbial fungicide and a preparation method and an application thereof. The method comprises the following steps: extracting a mushroom broth by an extractant, concentrating the material to a paste, and the paste and an auxiliary agent are used according to the mass volume ratio of 1g: 5mL to prepare the product. The mushroom broth extract fungicide contains natural antibacterial active metabolite, has wide-spectrum antibacterial and antifungal activities, can be used for inhibiting escherichia coli, pseudomonas solanacearum, tritirachium album, tobacco alternaria alternate and tobacco phytophthora, and can be used for preparing a food antiseptic or a biological pesticide. The preparation method is efficient, the obtained fungicide is the microbial source fungicide, and has the advantages of low toxicity and low residue.

The invention discloses gynecological anti-inflammatory antibacterial and bacteriostatic liquid. The gynecological anti-inflammatory antibacterial and bacteriostatic liquid comprises the following components: main drugs including 10.0% (w / w) of radix sophorae flavescentis, 0.3% (w / w) of borneol, 0.2% (w / w) of menthol and 0.008-0.012% (w / w) of trichloro-sym-diphenylurea; excipients including 100g of fructus cnidii, 100g of semen cuscutae, 100g of semen sapindi mukorossi, 150g of rhizoma cimicifugae, 200g of cortex phellodendri, 100g of radix angelicae sinensis, 20g of rhizoma chuanxiong, 50g ofborax and 50g of fructus foeniculi. The main ingredients in the components include the radix sophorae flavescentis; the radix sophorae flavescentis has effects of treating dysentery due to heat, hemafecia, jaundice anuresis, leukorrhea with reddish discharge, vulval swelling and pruritus vulvae and external treatment of trichomonas vaginitis; the borneol has the effect of treating blockage syndrome coma, sore red swollen eyes, sore and ulcer swelling and pain, non-astringency after ulcer breakage and the like; the menthol has effects of cooling and relieving itching; and the trichloro-sym-diphenylurea has effects of killing and inhibiting bacteria and deodorizing. The product has the effect of effectively inhibiting staphylococcus aureus (pyogenic coccus), tritirachium album (saccharomytes) and coliform (pathogenic entero becteria) and has an excellent effect of preventing gynecological diseases.

The invention discloses an application of a domestic silkworm cocoon antifungal protease inhibitor in fungus prevention and a separation method of the domestic silkworm cocoon antifungal protease inhibitor. The separation method comprises the following steps: layering and cutting a silkworm cocoon into pieces, then adding 100mm of Tris-HCL buffer solution with pH of 7.5, and extracting for 30 minutes under the condition that the temperature is 37 DEG C and the rotation speed is 220 r / pm, centrifuging for 15 minutes under the rotation speed of 10000rpm, filtering supernatant by utilizing a 0.22-micrometer filter membrane, to obtain the domestic silkworm cocoon antifungal protease inhibitor. The prepared protease inhibitor can inhibit the activity of fungal protease secreted by Tritirachium album limber, can inhibit the spore germination of silkworm pathogenic fungal beauveria bassiana and still can maintain the activity after being incubated for 10 minutes in boiled water. The prepared domestic silkworm cocoon antifungal protease inhibitor belongs to the natural, high-activity and high-stability antifungal protease and is non-toxic and harmless; and meanwhile, the silk used in the method is rich in resource, and a novel way is provided for diversified development of the silk.

The invention discloses a process for printing and dyeing antibacterial textiles. The particular method includes steps of 1), bleaching the textiles, to be more specific, impregnating the textiles in bleaching solution and washing and bleaching the textiles; 2), dyeing the textiles, to be more specific, heating the textiles at the speed of 2.5 DEG C / min until the temperatures of the textiles reach 70-75 DEG C, preserving heat of the textiles for 3-10 min, heating the textiles at the speed of 1.5 DEG C / min until the temperatures of the textiles reach 100 DEG C, preserving heat of the textiles for 5 min, heating the textiles at the speed of 1.5 DEG C / min until the temperatures of the textiles reach 120 DEG C, preserving heat of the textiles for 25-40 min, cooling the textiles at the speed of 2.5 DEG C / min until the temperatures of the textiles reach 60 DEG C and preserving heat of the textiles for 5-10 to completely dye the textiles; 3), carrying out antibacterial finishing, to be more specific, impregnating the dyed blended textiles in turnip extract aqueous solution at the normal temperature for 15-55 min and dewatering the dyed blended textiles; 4), drying the textiles and the like. The concentration of the turnip extract aqueous solution is 5 g / L-35 g / L. The method has the advantages that antibacterial weaving dye is low in production cost, bacteria represented as Escherichia coli, staphylococcus aureus and tritirachium album can be effectively suppressed, the suppression rate can reach 99%, and influence of conventional washing can be prevented.

The invention relates to a usage of an ocean fungal extract-active natural product B. According to the result of an in vitro research trial, the active natural product B has certain inhibitory effecton common clinical pathogenic fungi such as white tritirachium album limber, cryptococcus neoformans, trichophyton rubrum and aspergillus fumigatus and the like, is able to inordinately inhibit the growth of tumor cell lines such as liver cancer, breast cancer and lung cancer and the like, and is able to have stronger protective effect on pathological mechanism damages caused by rat multi-infarctcerebral ischemia damage and the like, thus being capable of obviously improving the learning and memory functions of dementia rat, and being applied to prepare dementia product having anti-angiogeniceffect. The invention provides a new pharmaceutical source for the curing of clinical antifungal, antitumor and anti-vascular dementia and directly related diseases thereof, having important value for developing and utilizing the pharmaceutical resource of our country.

The invention relates to a quaternary ammonium salt disinfectant composition and a method thereof. The quaternary ammonium salt disinfectant composition is characterized in that a host quaternary ammonium salt disinfectant composition is prepared from the following components in percentage by weight: 0.005% to 2.00% of single-chain quaternary ammonium salt, 0.005% to 3.00% of double-chain quaternary ammonium salt, 0.0001% to 0.001% of Cu2<+>-containing synergist, and the balance of solvent. The method comprises the step of fully and uniformly stirring the components at normal temperature to obtain the quaternary ammonium salt disinfectant composition. The quaternary ammonium salt disinfectant composition has good broad-spectrum germicidal efficacy, can effectively extinguish various bacteria such as escherichia coli, bacillus subtilis and staphylococcus aureus, and also can effectively extinguish various moulds such as blue mould, aspergillus niger and aspergillus flavus, as well as effectively extinguish various saccharomycetes such as tritirachium album. The quaternary ammonium salt disinfectant composition shows fast speed in sterilization, can extinguish more than 99.99% of various microorganisms within 1 to 2 minutes, is low in sterilization concentration, simple and convenient to prepare, low in cost and environmentally-friendly.

The invention discloses moistening anti-inflammatory lip pomade for children and a preparation method thereof. The lip pomade is prepared from the following raw materials in percentage by mass: 10 to 15 percent of jojoba oil, 10 to 15 percent of olive oil, 30 to 35 percent of glycerol caprylate, 8 to 12 percent of traditional Chinese medicine extraction paste, 1 to 3 percent of degenerating stage inactivated bacteria liquid and the balance propolis. The degenerating stage inactivated bacteria liquid is obtained through performing ultraviolet irradiation sterilization on tritirachium album liquid cultured to the degenerating stage; the traditional Chinese medicine extraction paste contains effective ingredients of aloe and purslane. The anti-inflammatory lip pomade has the safe recipe, is suitable for children to use, achieves the effects of effectively moisturizing the lip skin of the children, preventing the skin chapping, resisting bacteria and diminishing inflammation, and can be used for effectively preventing and treating lip diseases of angular cheilitis.

The invention discloses a yolk bioprotein foam filler which is mainly composed of 8-10% of multi-link yolk protein, 0.1-0.3% of preservative, 40-50% of matrix and the balance of a foamer.The multi-link yolk protein is yolk bioprotein capable of being combined with various pathogens, and the pathogens include, but not limited to ureaplasma urealyticum, mycoplasma hominis, staphylococcus, streptococcus, Escherichia coli, Gardnerella vaginalis, gonococcus and Tritirachium album.The yolk bioprotein foam filler is mainly composed of yolk bioprotein aiming at inhibiting pathogenic bacteria, can be combined with corresponding pathogens, can effectively inhibit and remove pathogens, is effective on most bacteria, mycete and mycoplasma, does not have impact on probiotics, can maintain health and physiological environment of a reproductive system, does not enter blood, is higher in safety during local use, is free of irritation and side effect on human body, dependency, drug resistance and hypersensitivity and can be used for various clinical therapeutic products for vaginitis.

The invention relates to fermentation production and preparation of an active product, belongs to the field of bioengineering and in particular relates to a prodigiosin (PG) producing strain as well as a preparation method and an application thereof. The PG producing strain is Proteus Vulgaris and is preserved on June 24th, 2013 in CGMCC (China General Microbiological Culture Collection Center) and has the preservation number of CGMCCNo.7815 and the preservation unit address of No.3 No.1 Courtyard, West Beichen Road, Chaoyang District, Beijing, Institute of Microbiology of Chinese Academy of Sciences. The PG producing strain can produce PG through fermentation, and an improved inorganic salt culture medium is adopted and is cultured for 18-24 hours at a culture temperature of 20-28 DEG C and a rotating speed of 150-300rpm, and yield of PG can be 80-120mg / L. The produced prodigiosin has an inhibitory activity to staphylococcus aureus, salmonella paratyphi, tritirachium album and pseudomonas aeruginosa and has a good application prospect in bio-preparation of the PG.

The invention discloses a preparation method of a mint fiber towel blanket with the antibacterial cooling function. The method comprises the following steps that a backing material is selected, an antibacterial solution is prepared, the backing material is soaked into the antibacterial solution, after soaking is completed, the backing material is taken out, and drying is performed; the dried backing material is processed, and the mint fiber towel blanket with the antibacterial cooling function. The preparation method of the mint fiber towel blanket with the antibacterial cooling function has the advantages that the good skin-friendliness of the fiber is ensured, the resisting and inhibiting effects are achieved on Escherichia coli, staphylococcus aureus, Tritirachium album and the like, and after repeated washing, the antibacterial property is still kept; due to the fact that the mint fiber component is contained, when the blanket is in use, the natural cool sense is achieved, the blanket is particularly suitable for being used in hot summer, the skin can be kept in cool and the heat preservation effect is achieved, after the blanket makes full contact with the skin, the temperature of the skin can be lowered, skincare and moisturizing are achieved, bacterium breeding can be effectively restrained, blood circulation can be promoted, and the body immunity can be improved.

The invention discloses a protease K heat-resistant mutant, and belongs to the field of gene engineering and enzyme engineering. According to the protease K heat-resistant mutant, From the molecular structure of Tritirachium album protease K, a mutant with improved thermal stability is obtained, an encoding protease K wild type and a mutant gene thereof are connected with a pPICZ alpha A plasmid to construct a recombinant expression vector, and the recombinant expression vector is transformed into pichia pastoris to construct a recombinant engineering bacterium for heterologous secretory expression. Compared with wild protease K, the protease K mutant PRK-7M provided by the invention has the advantages that the stability and the specific activity are greatly improved.

The invention belongs to the technical field of fermentation engineering and in particular relates to a prodigiosin producing strain and a method for producing prodigiosin through fermentation of the prodigiosin producing strain. The prodigiosin producing strain is acid producing klebsiella (Klebsiella oxytoca), is preserved on June 24th, 2013 in CGMCC (China General Microbiological Culture Collection Center) and has the preservation number of CGMCCNo.7816 and the preservation unit address of No.3 No.1 Courtyard, West Beichen Road, Chaoyang District, Beijing, Institute of Microbiology of Chinese Academy of Sciences. The prodigiosin producing strain can produce the prodigiosin through fermentation, an improved inorganic salt culture medium is adopted and is cultured away from light for 20-26 hours at a temperature of 24-28 DEG C and a rotating speed of 250-360rpm, and pigment yield can be 70-90mg / L. The produced prodigiosin is sensitive to natural light and ultraviolet rays and has an inhibitory activity to staphylococcus aureus, salmonella paratyphi and tritirachium album. The prodigiosin producing strain has a good application prospect in fermentation production of the prodigiosin and the fields of tumour suppression, food, cosmetics and the like.

The invention relates to fermentation production and preparation of an active product, belongs to the field of bioengineering and in particular relates to a prodigiosin (PG) producing strain as well as a preparation method and an application thereof. The PG producing strain is Proteus Vulgaris and is preserved on June 24th, 2013 in CGMCC (China General Microbiological Culture Collection Center) and has the preservation number of CGMCCNo.7815 and the preservation unit address of No.3 No.1 Courtyard, West Beichen Road, Chaoyang District, Beijing, Institute of Microbiology of Chinese Academy of Sciences. The PG producing strain can produce PG through fermentation, and an improved inorganic salt culture medium is adopted and is cultured for 18-24 hours at a culture temperature of 20-28 DEG C and a rotating speed of 150-300rpm, and yield of PG can be 80-120mg / L. The produced prodigiosin has an inhibitory activity to staphylococcus aureus, salmonella paratyphi, tritirachium album and pseudomonas aeruginosa and has a good application prospect in bio-preparation of the PG.

The invention discloses a biological preparation by aiming at urban sludge treatment. The biological preparation is prepared from biological extracts of Chinese honeylocust fruits, radix et rhizoma rhei, radix asparagi, bighead atractylodes rhizome, radix euphorbiae lantu, flaxseed, aloe and the like according to a certain proportion; the biological preparation has high activity inhibition effectson staphylococcus aureus, escherichia coli tritirachium album, fusarium, botrytis cinerea and rhizoctonia solani; raw liquid in a water solution is prepared from the following major ingredient: 5 to7 percent of Chinese honeylocust fruits, 2 to 4 percent of radix et rhizoma rhei, 5 to 7 percent of radix asparagi, 5 to 7 percent of bighead atractylodes rhizome, 5 to 7 percent of radix euphorbiae lantu, 3 to 5 percent of flaxseed and 5 to 8 percent of aloe. In the use process, the biological preparation is diluted by water to reach 1 to 200 times, better 25 to 150 times and optimal 50 to 100 times. The biological preparation simultaneously has the complexing action for eliminating free harmful heavy metal; further, nanoporous innocuous and innocent aerogel is added for adsorbing free stateheavy metal ions; then, ultraviolet light is used for irradiation for completely killing remaining bacteria; finally, dewatering and drying are performed to obtain a powdery organic solid fertilizer;storage and transportation can be further performed while granulation is performed. The biological preparation has the characteristics that the investment is low; the practicability is high; no secondary pollution exists; the wastes are comprehensively utilized.

The invention belongs to the technical field of research and development on medical products. The invention applies for the protection of a method for extracting components having antibacterial activity from fruit of pedunculate herpetospermum which is a Tibetan medicine. The method comprises: extracting coarse extract from the dried and crushed fruit of pedunculate herpetospermum by using a solvent and a solid-liquid extraction method, and concentrating the coarse extract to obtain extract; obtaining extract with obvious antibacterial effect by degreasing, concentrating and extracting; and further separating the extract by silica gel column chromatography and obtaining the effective extract components. The product of the invention has different inhibition effects on golden staphylococcus, tritirachium album, bacillus subtilis and salmonella, can be developed as a natural antibacterial to be used in medical industry and can be prepared into antibacterial tablets, granules, capsules, injection, skin external preparations and other formulations. Thus, a new field of the development of the pedunculate herpetospermum fruit Tibetan medicine is opened.