The invention discloses a spicy can containing mushroom and meat cubes and the processing process thereof, which belong to the field of food processing technology. The process comprises following steps: selecting mushroom, protecting color, pre-boiling, frying scented oil, frying, bottling, sterilizing, etc. The materials comprise mushroom 3 to 10 kg, vegetable oil 1.0 to 1.5 kg, Sichuan pepper 50 to 70 g, fennel 40 to 80 g, garlic 50 to 80 g, ginger 50 to 80 g, tomato sauce 70 to 100 g, chili 50 to 150 g, monosodium glutamate 30 to 50 g, salt 0.12 to 0.18 kg, ethyl maltol 0.8 to 0.5 g, beta-cyclodextrin 3 to 5 g, white sesame seeds 0.3 to 0.8 kg, peanut 0.3 to 0.6 kg, white sugar 40 to 70 g, TBHQ 25 to 50 g, and potassium sorbate 6 to 15 g. The invention solves the technical problems that fresh mushroom is difficult to be stored and the conventional mushroom product is likely to lose a great amount of nutrient and umami substances. The can has spicy and delicious taste, unique flavor and abundant nutrient, and can be used for seasoning vegetables, noodles, rice and steamed bread. The can is a necessary product for dietary.