49 results about "Nicergoline" patented technology

A freeze-dried powder injection is prepared from nicergoline, the acid as pH value regulator and the excipient for freeze-drying. Its preparing process is also disclosed.

The invention discloses nicergoline sublingual tablet and preparation method thereof. The nicergoline sublingual tablet is a sublingual mucosal administration non-quick-acting preparation prepared by comprising nicergoline raw material medicine, a filling agent, a disintegrating agent and a lubricating agent. In the sublingual tablet, the weight parts of the nicergoline is 1-20, the weight parts of the filling agent is 20-150, and the weight parts of the lubricating agent is 0.3-3.5. The nicergoline sublingual tablet has convenient use, small adverse reaction, good compliance, stable quality, slower release, sufficient absorption on the sublingual mucosa and high bioavailability.

The invention relates to the technical field of medicine, in particular to a nicergoline capsule and a preparation method thereof. The preparation method is characterized in that first, nicergoline and starch are mixed to be uniform, then a binder is added to be prepared into a mother pill, and finally a pill core is prepared; in the whole preparation process, the adopted kinds of auxiliary materials are fewer (2 kinds of auxiliary materials), the preparation process is simple, operation is easy, the pill core is good in fluidity, filling is easy, meanwhile, the main drug dissolution rate is high, the curative effect in clinical application is good, the side effects are fewer, and the compliance of a patient taking the medicine is good; according to similar kinds of medicine sold on the market, a large number of kinds of auxiliary materials are adopted, the preparation process is complicated, operation is hard, the curative effect in clinical application is poor, a large number of side effects are produced, and the compliance of the patient taking the medicine is poor. It shows that according to the novel nicergoline capsule and the preparation method thereof, the quality performance of the product is good, and medication safety of the patient is ensured.

The invention discloses nicergoline nasal powder and a preparation method thereof. In the nicergoline nasal powder, nicergoline dry powder and carrier dry powder are in a form of capsules or vesicles, the atomized nicergoline is sprayed to the nasal cavity by using a Helioeast dry powder administration device, and a preparation which is in brain targeting administration and treats vascular cretinism is absorbed by the mucous membrane of the nasal cavity. The nicergoline nasal powder contains 1-16 parts by weight of nicergoline dry powder with the particle diameter thereof being 80-250mum and 15-45 parts by weight of carrier dry powder with the particle diameter thereof being 80-250mum.The nicergoline nasal powder features convenient use, good conformability, quick acting of the brain targeting function and high bioavailability.

The invention discloses a medicine preparation form, especially discloses a nicergoline dry emulsion and the preparing method and application. It takes nicergoline in the dry emulsion as effective component, and also comprises oil phase, emulsifying agent and other findings. The dry emulsion is characterized by mature preparation process, easy industrialization, good stability, easy transportation and storage, controllable medicine content and good effect. The invention is used for improving cerebral arteriosclerosis and affective disorder caused by cerebral apoplexy after-effect, acute and chronic circulatory disturbance and acute urine retention resulted from blood vessel dementia and prostate gland proliferation.

The invention provides a traditional Chinese medicine preparation for treating senile dementia. The preparation is prepared from, by weight, 50-60 parts of bitter cardamon, 30-45 parts of acorus calamus, 9-15 parts of ginseng, 7-13 parts of ginkgo leaves, 8-14 parts of Tibetan hawksbeard roots, 10-16 parts of live charcoal brittle faslsepimpernel herb, 9-14 parts of vicia sativa, 7-15 parts of vitamin E, 9-16 parts of Beautiful Phyllodium Twig and Leaves, 15-20 parts of rhizoma atractylodis, 11-20 parts of nicergoline, 12-30 parts of licorice roots and 5-10 parts of eupatorium. The preparationis a pure traditional Chinese medicine preparation, and is high in safety, wide in application range and easily acceptable by a patient; the preparation is developed according to the traditional Chinese medicine principle, and has the effects of tonifying the kidney, reinforcing bones, soothing the nerves, restoring consciousness and the like; the preparation is good in curative effect, free of adverse reaction, low in cost and free of economic burdens after the patient takes the preparation for a long time.

An oral disintegrating tablet of nicergoline contains nicergoline and auxiliaries including sorbitol, methylacryl copolymer resin (Eudragit L30D), citric acid, sodium dicarbonate, magnesium stearate, SiO2 and lemon perfume.