Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Hiro

38 results about "Ne carboxymethyl lysine" patented technology

Detection method and application of carboxy methyl lysine ingredient in food

The invention relates to a detection method and application of a carboxy methyl lysine ingredient in food. The detection method comprises the following steps of: carrying out derivatization by a derivating agent after protein acid in a sample is hydrolyzed; obtaining solution to be detected from the derived solution by solid-phase extraction; carrying out qualitative and quantitative analysis on the carboxy methyl lysine ingredient in the food by adopting a tandem mass spectrometry of isotope dilution ultra-performance liquid chromatography, wherein the derivating agent is 9-fluorenylmethyl chloroformate.
Owner:FUJIAN INSPECTION & RES INST FOR PROD QUALITY +1

Method for detecting advanced glycation end products (AGEs) in main stream smoke of cigarette

The invention discloses a method for detecting advanced glycation end products (AGEs) in main stream smoke of a cigarette. The method specifically comprises analysis and determination of carboxy methyl lysine (CML) and carboxyethyl lysine (CEL). The method comprises the following steps: trapping total particulate matter of cigarette smoke by virtue of a Cambridge filter; carrying out ultrasonic extraction on the filter with a hydrochloric acid solution; and carrying out analysis by combining a cation exchange solid-phase extraction column purification method with liquid chromatogram-tandem mass spectrometry (LC-MS / MS). The method has the characteristics that (1) a detection method for AGEs in the main stream smoke of the cigarette is built for the first time; (2) a sample pretreatment method is built according to the characteristics of cigarette smoke sample matrix, derivative reaction is not required, and the pretreatment is simple and efficient; and (3) the method is high in sensitivity, good in qualitative accuracy and suitable for analysis of large batches of samples.
Owner:ZHENGZHOU TOBACCO RES INST OF CNTC

Carboxymethyl lysine fluorescence imprinting material and preparing method and application thereof

The invention discloses a carboxymethyl lysine fluorescence imprinting material and a preparing method and application thereof .According to the preparing method, thin layer nano material graphene is used as a carrier, a fluorescence nano material namely quantum dots excellent in optical performance is used as a response element, a molecularly imprinting polymer high in selectivity and specificity is used as a recognition element, an efficient, portable, fast and sensitive molecularly imprinting fluorescence sensing system is set up, carboxymethyl lysine is used as template molecules, 3-aminopropyl triethoxy silane is used as a functional monomer, tetraethoxy-silicane is used as a crosslinking agent, and ammonia water is used as a catalyst .The surface molecularly imprinting material based on graphene and quantum dots is prepared through a reversed-phase microemulsion synthesis method, and carboxymethyl lysine residues can be detected from food fast and easily .
Owner:BEIJING TECHNOLOGY AND BUSINESS UNIVERSITY

Class-I carboxymethyl lysine removing agent and application thereof

The invention discloses a class-I carboxymethyl lysine removing agent and application thereof. The removing agent is a quinones substance formed by the oxidization of polyphenol containing a catechol or pyrogallol structure unit. The removing agent is applied to the reduction of the content of carboxymethyl lysine in a food system. The quinones substance has stronger capability of removing AGEs (Advanced Glycation End Products) in the food system of which the pH is neutral or alkaline, and when the quinones substance is added after the food system generates the CML or before the CML is generated, the level of the CML in the system can be effectively reduced.
Owner:广东中旭农业股份有限公司

Detection method of free and combined carboxy methyl lysine in milk and dairy products

The invention discloses a detection method of free and combined carboxy methyl lysine in milk and dairy products. According to the detection method, isotope dilution high performance liquid chromatography- tandem ion trap mass spectrometry is adopted to detect free carboxy methyl lysine and carboxy methyl lysine combined with protein in milk and dairy products. According to the detection method, using of ion-pairing agent is avoided; no derivatization pretreatment is needed; efficiency, accuracy, sensitivity, and reproducibility are high; linearity range is wide; the detection method possesses unique features in analysis of the content of free carboxy methyl lysine and carboxy methyl lysine combined with protein in milk and dairy products, can be used for rapid and accurate qualitative and quantitative analysis on free carboxy methyl lysine and carboxy methyl lysine combined with protein in milk and dairy products, and can be used for detection of free and combined carboxy methyl lysine in milk and dairy products preferably.
Owner:WUHAN POLYTECHNIC UNIVERSITY

Methods for Improving Diabetes Management

A method for determining the levels of biomarkers, specifically, advanced glycation end products (AGEs) and oxidation products (Ops) in a biological sample such as a plasma ultrafiltrate, is used to determine a patient's risk and / or rate of developing diabetes related nephropathy. The preferred biomarkers to measure include Nε-(1-carboxyethyl-lysine (CEL), methylglyoxyl-derived hydroimidazolone (MGHI) and Nε-carboxymethyllysine (CML). Also provided herein is a method of diabetic care which includes determining a diabetic patient's risk of developing diabetes related kidney disease and adjusting the patient's treatment regimen to include in addition to glucose lowering agents, additional treatments such as medications that modify the renin-angiotensin system, or specialized diets with low levels of AGEs or oxidative products.
Owner:PREVENTAGE HEALTHCARE

Detecting method of carboxymethyl lysine and application thereof

The invention discloses a detecting method of carboxymethyl lysine (CML). The method is characterized by measuring the content of the CML in food adopting high performance liquid chromatography-tandem mass spectrometry in combination with an HILIC (Hydrophilic Interaction Liquid Chromatography) column for strong-polarity CML separation under a higher organic phase proportion. Crushed food passes through an MCX (Mixed-Mode Cation-Exchange) small column for being extracted and purified after being reduced by sodium borohydride and hydrolyzed by hydrochloric acid; sample liquor is subjected to gradient elution in the HILIC column by taking methanol-water (containing 2 mM ammonium acetate and 0.1% formic acid) as a mobile phase, so that CML is separated from a sample substrate; tandem mass spectrum analysis is carried out by using an electrospray ion source, positive ion scanning and a multi-reaction monitoring mode; quantitative analysis is carried out by using D4-CML as an internal standard substance, wherein analysis time is 12 minutes, and CML has an absorption peak at the retention time of 3.47 minutes. The detecting method disclosed by the invention is high in sensitivity, high in accuracy and good in precision, does not need to carry out derivatization onto samples, simplifies sample pre-treatment, shortens detecting time and saves detecting cost.
Owner:SHANGHAI OCEAN UNIV

Method for detecting advanced glycation end-products in aquatic product

The invention provides a method for detecting advanced glycation end-products (AGEs) in an aquatic product by using liquid chromatography-tandem mass spectrometry. The method comprises the following steps of: 1, extracting AGEs; 2, making a standard curve: drawing the standard curve by taking the concentration value of a standard substance as the abscissa and taking the standard substance area*(internal standard substance concentration / internal standard substance area) as the ordinate to obtain an equation; and 3, subjecting the treated sample to HPLC-MS / MS detection in a detection mode of MRMto obtain the AGEs peak area in the sample, and acquiring the AGEs concentration in the sample. The invention aims to establish the liquid chromatography-tandem mass spectrometry method, which can detect three AGEs (carboxymethyl lysine (CML), carboxyethyl lysine (CEL) and methyl glyoxal hydroimidazolone MG-H1) at one time and has the advantages of good separation degree, good linear relationship, wide linear range and the like.
Owner:OCEAN UNIV OF CHINA

Method for detecting carboxy methyl lysine (CML) in soybean sauce

The invention relates to a method for detecting carboxy methyl lysine (CML) in soybean sauce. The method comprises the following steps: firstly, carrying out detection pretreatment on CML in a soybean sauce system, namely, detection pretreatment on free-state CML and combined-state CML; carrying out detection pretreatment on the free-state CML, namely sampling, adding a methanol solution to dilute, swirling and evenly mixing, purifying through a C18 solid-phase extraction column, adding a methanol solution to elute, filtering through a micro-filtration membrane to obtain a sample 1 to be detected; carrying out the detection pretreatment on the combined-state CML, namely sampling, reducing through sodium borohydride, separating polypeptide and protein through a dialysis bag, hydrolyzing through hydrochloric acid, disacidifying through vacuum, purifying through the C18 solid-phase extraction column, filtering through the micro-filtration membrane, drying in vacuum, re-dissolving to obtain a sample 2 to be detected; and subsequently, carrying out CML detection on the sample 1 and the sample 2 to be detected respectively. A total content of the CML is sum of the content of the free-state CML and the content of the combined-state CML. The sample pretreatment method has the characteristics of elimination of interference, protection of chromatographic column, safety and reliability, and capability of completely analyzing all the CML in the soybean sauce.
Owner:SOUTH CHINA UNIV OF TECH +1

Vinasse extract and preparation method and application thereof

The invention provides a vinasse extract and a preparation method and application thereof. The extraction method comprises the following steps that in a protective atmosphere, trioctylphosphine-modified CdSe / ZnS quantum dots, glyoxal dimethacrylate, 4-vinyl pyridine and gallic acid are subjected to reaction in xylene when initiated by azodiisobutyronitrile, after purification and drying are conducted, filler for extracting an antioxidant component of vinasse is obtained, and a solid-phase extraction cartridge is prepared; the vinasse is added into ethyl alcohol-water mixed liquid for heating and stirring, and extraction liquid is collected; the homemade solid-phase extraction cartridge is used for extracting the vinasse component, and after drying is conducted, the vinasse extract is obtained. The vinasse extract obtained through the method contains a phenolic acid substance, and can be used as a food additive for inhibiting carboxy methyl lysine in a food processing process, novel application of the white liquor vinasse is extended, and a novel path is provided for resource utilization of the vinasse. The method for preparing the vinasse extract is simple and convenient in extraction process and low in cost, industrialized application is easy, and the vinasse can be subjected to mass treatment.
Owner:BEIJING TECHNOLOGY AND BUSINESS UNIVERSITY

Method for inhibiting the production of carboxymethyllysine during thermal processing of minced fish products

The present invention discloses a method for inhibiting the production of carboxymethyllysine during the thermal processing of minced fish products. The method includes the following specific steps: during the chopping and mixing of the minced fish, carboxymethyllysine inhibitors with mass of 0.3-0.8% of the mass of the minced fish are added; the carboxymethyllysine inhibitors are prepared from glutamine transaminage and chitosan oligosaccharides with a mass ratio of 1 to 1-1.1 through mixing. Carboxymethyllysine inhibitors which consist of transglutaminase and chitosan oligosaccharides are added during the chopping and mixing of the minced fish to achieve the purposes of inhibiting the production of carboxymethyllysine during the thermal processing of the minced fish products. The processing steps are simple, are strong in operability, and have great popularization and application values.
Owner:OCEAN UNIV OF CHINA

Silicon dioxide particle composite material coated with polymeric ionic liquid, preparation method of composite material and application of composite material in removal of carboxy methyl lysine in fermented soy sauce

The invention discloses a silicon dioxide particle composite material coated with polymeric ionic liquid, a preparation method of the composite material and application of the composite material in removal of carboxy methyl lysine in fermented soy sauce, and belongs to the technical field of food safety and quality. The silicon dioxide particle composite material coated with the polymeric ionic liquid is prepared from silicon dioxide particles, polyethylene nonylphenol ether and propyl alcohol through an emulsion polymerization method. The preparation method comprises the specific steps that the silicon dioxide particles, polyethylene nonylphenol ether, functionalized ionic liquid containing vinyl and propyl alcohol are mixed and ultrasonically dispersed; the materials are heated to 70 DEG C to 76 DEG C under nitrogen protection, and reacting under stirring is conducted for 24 hours to 48 hours; the materials are cooled to room temperature, centrifugal separation is conducted, the collected solid phase is the silicon dioxide particle composite material coated with the polymeric ionic liquid, and the composite material is used for removing carboxy methyl lysine in the fermented soy sauce. The method is easy and convenient to operate, low in cost, simple in treatment technology and high in removal efficiency.
Owner:SOUTH CHINA UNIV OF TECH

Method for detecting AGEs (Advanced Glycation End Products) and application

The invention discloses a method for detecting AGEs (Advanced Glycation End Products) and application. The method comprises the following steps: firstly preparing a glassy carbon electrode modified bygraphene-chitosan / N(epsilon)carboxymethyl lysine, and then realizing multi-residue detection on five AGEs comprising the N(epsilon)carboxymethyl lysine, N(epsilon)carboxyethyl lysine, pentosidine, pyruvaldehyde imidazolinone and argpyrimidine by combining an indirect competition method on the basis of a principle that cross immunoreaction can be generated by a pentosidine monoclonal antibody andmultiple AGEs. According to the method for detecting the AGEs, disclosed by the invention, the problem that a current AGEs detecting method just can be used for detecting a single substance is solved,higher sensitivity (of which the detecting limit is 0.06 to 0.1 ng / mL) and wider linear range (0.1 to 1000 ng / mL) are obtained, the operation is simple, the cost is lower, the demands on clinical AGEs detection of a human body can be completely fitted, and important practical application value is obtained.
Owner:NANJING NORMAL UNIVERSITY

Method for preparing precursor used for labeling hepatocyte receptor and containing trisaccharide and DTPA ligand

A method for preparing a precursor used to label hepatocyte receptors is revealed. The precursor contains a bifunctional structure including trisaccharide and DTPA ligand. During synthesis processes of the precursor, silica gel columns and Reverse phase-18 (RP-18) columns are used for purification. Thus both the purification times and cost of each purification are reduced. Moreover, use diethyl ether to facilitate precipitation of products and remove a part of coupling reagent. Removing the coupling reagent helps purification of products. Furthermore, Nα,Nα-bis(carboxymethyl)-L-lysine hydrate and benzyl chloroformate are coupled to form a trisaccharide skeleton so as to ensure the yield rate of trisaccharide structure.
Owner:ATOMIC EMERGY COUNCIL INST OF NUCLEAR ENERGY RES

A kind of detection method and application of carboxymethyl lysine

The invention discloses a detecting method of carboxymethyl lysine (CML). The method is characterized by measuring the content of the CML in food adopting high performance liquid chromatography-tandem mass spectrometry in combination with an HILIC (Hydrophilic Interaction Liquid Chromatography) column for strong-polarity CML separation under a higher organic phase proportion. Crushed food passes through an MCX (Mixed-Mode Cation-Exchange) small column for being extracted and purified after being reduced by sodium borohydride and hydrolyzed by hydrochloric acid; sample liquor is subjected to gradient elution in the HILIC column by taking methanol-water (containing 2 mM ammonium acetate and 0.1% formic acid) as a mobile phase, so that CML is separated from a sample substrate; tandem mass spectrum analysis is carried out by using an electrospray ion source, positive ion scanning and a multi-reaction monitoring mode; quantitative analysis is carried out by using D4-CML as an internal standard substance, wherein analysis time is 12 minutes, and CML has an absorption peak at the retention time of 3.47 minutes. The detecting method disclosed by the invention is high in sensitivity, high in accuracy and good in precision, does not need to carry out derivatization onto samples, simplifies sample pre-treatment, shortens detecting time and saves detecting cost.
Owner:SHANGHAI OCEAN UNIV

The method used to study the inhibitory effect of pqq on ages

The invention relates to a method for researching an inhibiting effect of PQQ (pyrroloquinoline quinone) on AGEs. The method is a researching result of the inhibiting effect of PQQ and later period glycosylation end product AGEs after the method for searching on reaction of PQQ, Lys and Arg and belongs to the technical field of bioanalysis. N epsilon-(carboxymethyl)lysine (CML) and N epsilon-(carboxyethyl)lysine (CEL) are two of the most primary monomers of AGEs. The invention optimizes and improves the method for determining CML and CEL, adopts n-butanol / HCl derivative reaction, solid-phase extraction and UPLC-MS / MS for detecting the contents of CML and CEL in plasma and has the characteristics of high efficiency, accuracy and sensitivity; the established method is adopted for analyzing the change of CML, CEL, protein-binding CML and protein-binding CEL after a D-gal (D-galactose) induced aging rat is intervened with a certain amount of donepezil (Don) and PQQ, so as to supply a new basis for pathogenesis and drug targets of degenerative diseases.
Owner:JIANGSU INST OF NUCLEAR MEDICINE

A distiller's grain extract and its preparation method and application

The invention provides a distiller's grain extract, a preparation method and application thereof. The extraction method is as follows: in a protective atmosphere, CdSe / ZnS quantum dots modified by trioctylphosphine, glyoxal dimethacrylate, 4-vinylpyridine and gallic acid were induced by azobisisobutyronitrile in two React in toluene, purify and dry to obtain the filler for extracting the antioxidant components of distiller's grains, and prepare it into a solid phase extraction column; add the distiller's grains to the ethanol-water mixture, heat and stir, and collect the extract; use the self-prepared solid phase extraction column Distiller's grain components are extracted, and distiller's grain extract is obtained after drying. The distiller's grain extract obtained by this method contains phenolic acids and can be used as a food additive to inhibit the production of carboxymethyllysine during food processing, expanding the new application of distiller's grains in liquor and providing a new source for resource utilization of distiller's grains way. The method for preparing distiller's grains extract provided by the invention has the advantages of simple and convenient extraction process, low cost, easy industrial application, and large amount of distiller's grains can be processed.
Owner:BEIJING TECHNOLOGY AND BUSINESS UNIVERSITY

Polymerized ionic liquid-coated silica particle composite material and its preparation method and its application in removing carboxymethyllysine from brewed soy sauce

The invention discloses a silicon dioxide particle composite material coated with polymeric ionic liquid, a preparation method of the composite material and application of the composite material in removal of carboxy methyl lysine in fermented soy sauce, and belongs to the technical field of food safety and quality. The silicon dioxide particle composite material coated with the polymeric ionic liquid is prepared from silicon dioxide particles, polyethylene nonylphenol ether and propyl alcohol through an emulsion polymerization method. The preparation method comprises the specific steps that the silicon dioxide particles, polyethylene nonylphenol ether, functionalized ionic liquid containing vinyl and propyl alcohol are mixed and ultrasonically dispersed; the materials are heated to 70 DEG C to 76 DEG C under nitrogen protection, and reacting under stirring is conducted for 24 hours to 48 hours; the materials are cooled to room temperature, centrifugal separation is conducted, the collected solid phase is the silicon dioxide particle composite material coated with the polymeric ionic liquid, and the composite material is used for removing carboxy methyl lysine in the fermented soy sauce. The method is easy and convenient to operate, low in cost, simple in treatment technology and high in removal efficiency.
Owner:SOUTH CHINA UNIV OF TECH

Carbon nano tube ionic liquid composite material, and preparation method and application thereof to remove carboxymethyl lysine in soy sauce brewing

The invention discloses a carbon nano tube ionic liquid composite material, and a preparation method and application thereof to remove carboxymethyl lysine in soy sauce brewing. The carbon nano tube ionic liquid composite material is prepared according to the steps that firstly, functionalized ionic liquid containing allyl groups, ethanol and alkane is used for preparing a ternary ingredient surfactant-free microemulsion system; a carbon nano tube is added; the carbon nano tube ionic liquid composite material is prepared by an emulsion polymerization method. The method comprises the concrete steps that the functionalized ionic liquid containing allyl groups, the ethanol and the alkane are mixed and are stirred for 1 to 4h at room temperature; then, the carbon nano tube is added; the mixture is heated to 70 to 85 DEG C under the nitrogen gas protection; after the reaction is performed for 1 to 3h, the mixture is cooled to room temperature; centrifugal separation is performed; the obtained solid is the carbon nano tube ionic liquid composite material; the carbon nano tube ionic liquid composite material is used for removing the carboxymethyl lysine in soy sauce brewing. The method has the advantages that the operation is simple and convenient; the cost is low; the treatment process is simple; the removal efficiency is high.
Owner:SOUTH CHINA UNIV OF TECH

Nano magnetic microsphere with hollow core-shell structure as well as preparation method and application of nano magnetic microsphere

The invention provides a nano magnetic microsphere with a hollow core-shell structure as well as a preparation method and application of the nano magnetic microsphere. The method comprises the following steps: providing Fe3O4 nano magnetic microspheres; enabling the Fe3O4 nano magnetic microspheres to react with hexadecyl trimethyl ammonium bromide and tetraethyl silicate in ethanol to obtain Fe3O4@mSiO2 with a hollow core-shell structure; ultrasonically dispersing in ethanol, and adding glycidyl oxypropyl trimethoxy silane to obtain Fe3O4@mSiO2@GPS; ultrasonically dispersing in tetrahydrofuran, and adding NH2-PEGn-NH2 to obtain amino-modified Fe3O4@mSiO2@NH2 nano magnetic microspheres; ultrasonically dispersing in 2, 4-epoxyhexane or tetrahydrofuran, adding N, N-carbonyl diimidazole to react, dispersing in an alkaline buffer solution, and adding N alpha, N alpha-bis (carboxymethyl)-L-lysine to obtain carboxylic acid modified Fe3O4@mSiO2@NTA; and ultrasonically dispersing in a ferric trichloride solution to obtain a finished product.
Owner:INST OF ANIMAL SCI OF CHINESE ACAD OF AGRI SCI

A method for measuring the freshness of royal jelly

A new method for measuring the freshness of royal jelly is disclosed. The method mainly monitors the freshness of the royal jelly by measuring the glycosylation terminal products Pentodilysin and CML (carboxymethyllysine) in the royal jelly by three-dimensional fluorescence spectroscopy and ELISA (enzyme-linked immunosorbent) method respectively. So far, there is no internationally recognized index that can truly reflect the freshness of royal jelly and can be promoted in practical applications.
Owner:BEE RES INST CHINESE ACAD OF AGRI SCI

An activated carbon felt-supported polymeric ionic liquid composite material and its preparation method and its application in removing carboxymethyllysine from brewed soy sauce

An activated-carbon-felt loaded polymerized ionic liquid composite material, a preparing method thereof, and an application of the composite material for removing carboxymethyl lysine from brewed soy sauce are disclosed and belong to the technical field of food safety and quality. The invention includes preparation of the composite material and the application of the composite material for removing carboxymethyl lysine from brewed soy sauce. The composite material is prepared by adsorbing an allyl-containing functional ionic liquid by utilizing an activated carbon felt and performing heating polymerization, and is used for removing carboxymethyl lysine from brewed soy sauce. The method is simple and convenient in operation, low in cost, simple in processing process and high in removing efficiency.
Owner:SOUTH CHINA UNIV OF TECH

Method for measuring interaction efficiency of quinones substances and carboxymethyl lysine in solution

The invention discloses a method for measuring the interaction efficiency of quinone substances and carboxymethyl lysine (CML) in a solution. The method comprises the following steps: respectively recording peak current and voltage characteristic values of the catechol substance solution before and after the CML is added by measuring a cyclic voltammetry curve of the catechol substance solution before and after the CML is added; and calculating the reduction rate of reduction peak current to obtain the interaction efficiency of the quinone substance in the solution and the CML. In the method,after the phenolic substance is oxidized to form the quinone substance, the quinone substance can rapidly interact with CML in a system, so that the side reaction of the quinone substance is reduced;the amount of the substance attached to the surface of an electrode is small, and the detection accuracy is high; the interference of factors such as the attachment of polyphenol and oxidation products thereof on a working electrode, the related side reaction of quinone substances and the like on the interaction of the quinone substances and CML in the prior art is reduced; and meanwhile, the method for measuring the interaction efficiency of quinone substances and carboxymethyl lysine in the solution is simple, short in analysis time, good in repeatability and convenience, low in use cost andwide in application.
Owner:DONGGUAN UNIV OF TECH

Method for detecting carboxy methyl lysine (CML) in soybean sauce

The invention relates to a method for detecting carboxy methyl lysine (CML) in soybean sauce. The method comprises the following steps: firstly, carrying out detection pretreatment on CML in a soybean sauce system, namely, detection pretreatment on free-state CML and combined-state CML; carrying out detection pretreatment on the free-state CML, namely sampling, adding a methanol solution to dilute, swirling and evenly mixing, purifying through a C18 solid-phase extraction column, adding a methanol solution to elute, filtering through a micro-filtration membrane to obtain a sample 1 to be detected; carrying out the detection pretreatment on the combined-state CML, namely sampling, reducing through sodium borohydride, separating polypeptide and protein through a dialysis bag, hydrolyzing through hydrochloric acid, disacidifying through vacuum, purifying through the C18 solid-phase extraction column, filtering through the micro-filtration membrane, drying in vacuum, re-dissolving to obtain a sample 2 to be detected; and subsequently, carrying out CML detection on the sample 1 and the sample 2 to be detected respectively. A total content of the CML is sum of the content of the free-state CML and the content of the combined-state CML. The sample pretreatment method has the characteristics of elimination of interference, protection of chromatographic column, safety and reliability, and capability of completely analyzing all the CML in the soybean sauce.
Owner:SOUTH CHINA UNIV OF TECH +1
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products