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34 results about "Improved exercise tolerance" patented technology
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Packed Beverage For Lipid Combustion Promotion
InactiveUS20090148554A1Organic active ingredientsFruit and vegetables preservationCombustionAdditive ingredient
There are provided packaged beverages for fat-burning acceleration, energy-consumption boosting or exercise-endurance enhancement, each solution containing a green tea extract added therein and having a pH of from 2 to 7, and also containing the following ingredients (A) to (C):(A) from 0.01 to 1.0 wt % of non-polymer catechins,(B) from 0.001 to 0.5 wt % of sodium ions, and(C) from 0.001 to 0.2 wt % of potassium ions.The ingestion of these beverages can accelerate fat-burning, can boost energy consumption, or can enhance exercise endurance.
Owner:KAO CORP
Compound for delaying senescence of human mesenchymal stem cells and application of same
The invention discloses the applications of compounds, selected from quercetin, chrysophanic acid, digicitrine, formononetin, honokiol, berberine, kaempferol, bergenin, deoxyepinephrine and licochalcone A, as well as derivatives thereof, in preparation of medicines applied to methods that are used for promoting stem cell proliferation, delaying senescence of stem cells, promoting differentiation of the stem cells into osteoblasts, chondrocytes and adipocytes, enhancing the vascularization capability of the stem cells and / or improving exercise tolerance of mice. The invention also discloses that the compounds can be combined with vitamin C for application.
Owner:INST OF ZOOLOGY CHINESE ACAD OF SCI
Rhodiola root health care cake
InactiveCN102715221AAdd new flavorsImprove exercise enduranceDough treatmentBakery productsImproved exercise toleranceAsthma
The invention provides a rhodiola root health care cake, relating to a health care cake. The technical scheme of the invention is as follows: the rhodiola root health care cake comprises the following raw materials in parts by weight: 5-20 parts of rhodiola root powder, 1-3 parts of liquorice root extract, 4-15 parts of honey, 110-130 parts of cake flour, 70-90 parts of milk, 2-4 parts of baking powder, 160-200 parts of egg white, 60-80 parts of egg yolk, 20-50 parts of berry sugar and 0.03-0.05 part of potassium acid tartrate. The rhodiola root health care cake provided by the invention increases a new cake taste and has richer nutrition; rhodiola root has the effects of enhancing exercise tolerance, resisting oxidation, resisting diabetes, resisting tumors and resisting pneumonia and asthma; and in addition, the honey has the effects of nutrition and health care, so that the functions of nutrition and health care of the cake are enhanced.
Owner:蒋泳
Composition containing Haematococcus pluvialis
ActiveCN103918966AImprove antioxidant capacityIncrease productionFood ingredient functionsFood preparationMechanism of actionSaussurea involucrata
The invention relates to a composition containing Haematococcus pluvialis. The composition comprises the following components by weight: 1-40 parts of Haematococcus pluvialis, 1-10 parts of a Saussurea involucrata culture, 10-40 parts of acerola cherry powder and 40-80 parts of oligosaccharide. The composition provided by the invention can improve exercise tolerance and delay fatigue, and the mechanism of action is probably related to increase of the body's SOD content and decrease of the body's MDA content. Also, the composition has exercise tolerance improving and fatigue delaying effects superior to the prior art, and has a synergistic effect.
Owner:BEIJING TONGRENTANG HEALTH PHARMA
Genetic risk assessment in heart failure: impact of genetic variation of beta 1 adrenergic receptor gly389arg polymorphism
InactiveUS20090192128A1Reduce mortalityIncreased oxygen consumptionBiocideMicrobiological testing/measurementAntioxidantLeft ventricular size
The invention provides methods for (a) reducing mortality associated with heart failure; (b) improving oxygen consumption; (c) treating heart failure; (d) treating hypertension; (e) improving the quality of life in a heart failure patient; (f) inhibiting left ventricular remodeling; (g) reducing hospitalizations related to heart failure; (h) improving exercise tolerance; (j) increasing left ventricular ejection fraction; (k) decreasing levels of B-type natriuretic protein; (l) treating renovascular diseases; (m) treating end-stage renal diseases; (n) reducing cardiomegaly; (o) treating diseases resulting from oxidative stress; (p) treating endothelial dysfunctions; (q) treating diseases caused by endothelial dysfunctions; or (r) treating cardiovascular diseases; in a patient in need thereof, wherein the patient has a Arg389Arg polymorphism and / or a Gly389Gly polymorphism in the beta 1 adrenergic receptor gene, comprising administering to the patient (i) at least one antioxidant compound or a pharmaceutically acceptable salt thereof; (ii) at least one nitric oxide enhancing compound; and (iii) optionally the best current therapy for the treatment of cardiovascular diseases. In one embodiment the antioxidant is a hydralazine compound or a pharmaceutically acceptable salt thereof and the nitric oxide enhancing compound is isosorbide dinitrate and / or isosorbide mononitrate.
Owner:NITROMED +1
Beverage with function of quick physical energy recovery and method for preparing beverage with function of quick physical energy recovery
InactiveCN105661234AImprove staminaEffective anti-fatigueInorganic compound food ingredientsNatural extract food ingredientsMagnesium saltPotassium
The invention discloses a beverage with a function of quick physical energy recovery and a method for preparing the beverage with the function of quick physical energy recovery.The beverage is mainly prepared from taurine, inositol, L-tyrosine, AAKG, potassium salt, magnesium salt, citrulline malate, guarana extract, glucuronolactone, maltodextrin, D-ribose, citric acid, potassium sorbate, flavoring agents and the balance purified water.The method includes: dissolving sweeteners into an appropriate amount of purified water and filtering; adding the taurine, the inositol, the L-tyrosine, the AAKG, the potassium salt, the magnesium salt, the citrulline malate, the guarana extract, the glucuronolactone and the like into purified water, dissolving completely, and filtering; well mixing the two solutions, adding the citric acid, the potassium sorbate and the flavoring agents, well mixing, and performing high-temperature sterilization and filling to obtain finished products.The beverage with the function of quick physical energy recovery is capable of not only regulating body fluid equilibrium and improving exercise tolerance but also enhancing anti-fatigue ability and promoting fatigue recovery after exercises.
Owner:JIANGSU ALAND NOURISHMENT
Fruity nutrient beverage formula for enhancing explosive power and production process thereof
ActiveCN105410548AIncrease contentIncrease flexibilityNatural extract food ingredientsFood ingredient functionsVitamin CFruit juice
The invention discloses a fruity nutrient beverage formula for enhancing explosive power. The fruity nutrient beverage formula for enhancing the explosive power is characterized in that per L(liter) of the beverage is prepared from the following components by weight: 50-70g of white granulated sugar, 6-8g of honey, 2-8g of isomaltulose, 4-12g of fructose, 0.2-0.4g of magnesium sulfate heptahydrate, 0.1-0.3g of potassium citrate, 0.12-0.18g of sodium citrate, 0.9-1.2g of citric acid monohydrate, 0.3-0.6g of vitamin C, 0.02-0.1g of vitamin E, 0.3-0.5g of taurine, 10-18mg of nicotinic acid, 1-1.6mg of vitamin B6, 1-1.8 micrograms of vitamin B12, 50-180g of fruit juice, 0.1-0.5g of wolfberry powder, 0.1-0.5g of black tea powder, 0.01-0.12g of ginseng extract, 0.1-0.5g of grape powder, 0.1-0.5g of maca powder, 1.0-1.4g of guarana extract, a proper amount of essence and the balance of water. Compared with the prior art, the fruity nutrient beverage formula for enhancing the explosive power has the effects of improving the explosive power, resisting exercise fatigue and improving exercise tolerance. The invention also provides a production process of the fruity nutrient beverage for enhancing the explosive power.
Owner:FOSHAN SANSHUI JIANLIBAO TRADE
Novel probiotic dendrobium enzyme and production technology thereof
ActiveCN105146509APromote Microecological BalanceRegulate metabolismMetabolism disorderDigestive systemFermentationImproved exercise tolerance
The invention relates to a novel probiotic dendrobium enzyme and production technology thereof and belongs to the technical field of biological medicine. The technology comprises the following nine major steps, namely collecting dendrobium leaves and removing impurities, grinding the dendrobium leaves, carrying out first fermentation, selecting jerusalem artichoke powder, making matrix for second fermentation, acclimatizing and preparing strains for second fermentation, grafting probiotic mother strains of fermentation and performing a second fermentation process, performing a blend process and adding probiotics, carrying out filling and performing packaging. Pharmacological functions of the waste dendrobium leaves, repair functions of the compound probiotics to the micro-ecological environment of the digestive tract and promotion functions of the probiotics to the probiotic floras in the digestive tract are fully utilized in the production technology, so that physiological functions of human body are systematically adjusted by synergetic effects of the three aspects. The probiotic dendrobium enzyme of the invention is capable of promoting micro-ecological environment balance of the digestive tract, obviously improving digestive functions, adjusting organism metabolism and adjusting immunologic function; moreover, the probiotic dendrobium enzyme also has the health-care functions of improving exercise tolerance, accelerating tiredness allaying and protecting the liver.
Owner:昆明宝成生物科技有限公司
Liquid preparation with functions of improving exercise tolerance and helping exercise recovery
PendingCN111228468AIn line with the concept of sports nutritionPromote the body's metabolismDispersion deliveryPeptide/protein ingredientsBiotechnologyVitamin b6
The invention belongs to the field of nutrition and health care, and relates to a liquid preparation with functions of improving exercise tolerance and helping exercise recovery. The liquid preparation is prepared from L-carnitine, L-carnitine tartrate, a blood orange-guarana-elderberry extract, vitamin B1, vitamin B2, vitamin B6, vitamin C, creatine, beta-hydroxyl-beta-calcium methylbutyrate, collagen peptide and Arabic gum through dissolution after self-adhesion and self-embedding. The liquid preparation adopts a reasonable formula according to an exercise nutrition principle, has the functions of reducing fat and helping exercise recovery under the multi-way synergistic effect, can effectively reduce the gastric acid loss rate and oriented absorption to improve the taking effect by self-adhesion and self-embedding technologies, and has the advantages of being simple to eat.
Owner:浙江赛沛力运动科技有限公司
Application of red beet as edible plant source nitric oxide replenisher
InactiveCN106727751AGood for healthFunction increaseAntipyreticAnalgesicsNitro compoundVascular endothelium
The invention provides application of red beet as an edible plant source nitric oxide replenisher. Nitrocompounds in red beet are all soluble in water and can be effectively converted into nitric oxide in the human body. The edible nitric oxide replenisher can generate nitric oxide without mitochondria aldehyde dehydrogenase and generate the transition product nitrous acid group through salivary gland nitrate reductase, and the nitrous acid group enters a blood circulation system and is converted into nitric oxide in a hypoxia area of endothelium. The nitrocompound group has a remarkable cardiovascular health improving effect. After Chinese people whose acetaldehyde dehydrogenase genes have R671 polymeric morphism (G / A) drink red beet juice, hypertension can be effectively relieved, and the vascular endothelial function can be effectively improved. Nitric oxide is an active molecule with multiple functions. Besides the cardiovascular health improving effect, nitric oxide can also resist inflammation, improve oxygen supply, improve blood flow and enhance exercise tolerance. Therefore, red beet products have an extensive and practical development and application value.
Owner:得力奥(广州)生物科技有限公司
Novel application of sea horse extract
PendingCN107684049AIncrease exercise toleranceReduce fatigueDigestive systemMuscular disorderAdditive ingredientImproved exercise tolerance
Owner:GUANGDONG OCEAN UNIVERSITY
Complex nutriment of tribulus terrestris extract, glutamine, taurine, various trace elements and vitamins
InactiveCN104855953AReduce exercise fatigueImprove exercise enduranceFood preparationTaurineImmunologic function
The present invention relates to a complex nutriment of tribulus terrestris extract, glutamine, taurine, various trace elements and vitamins. The main ingredient of this complex supplement (per bag or per 250 ml) includes tribulus terrestris extract (containing more than 60% saponin) 200-500 mg, glutamine 250-750 mg, taurine 40-150 mg; various trace elements: zinc 5-10 mg, potassium 50-100 mg, calcium 500-800 mg and iron 5-10 mg; and a variety of water-soluble vitamins: antioxidant vitamin C 50-80 mg, various coenzyme B-vitamins which consists of B1 2.0-3.0 mg, B2 1.0-1.5 mg, B6 1.5-2.3 mg and B12 0.001-0.003 mg, and folic acid 0.2-0.4 mg. Gross saponins of tribulus terrestris (GSTT) can improve the immune function of over-training rats, improve the endurance of over-training and high-intensity exercising rats, and delay the occurrence of sport fatigue. The compound prescription of the complex nutriment mainly makes use of GSTT, glutamine and taurine, supplements a variety of vitamins and trace elements, and thus has functions of delaying sport fatigue, enhancing exercise endurance and improving immunity.
Owner:SHANGHAI UNIV OF SPORT
Solid beverage formula for improving exercise tolerance and preparation method thereof
PendingCN114158669AGood for healthTo promote metabolismSugar food ingredientsInorganic compound food ingredientsBiotechnologyPhysical exhaustion
The invention discloses a solid beverage formula capable of improving exercise tolerance, which is prepared from the following formula components in parts by weight: 10 to 20 parts of D-ribose, 6 to 30 parts of L-carnitine, 1 to 20 parts of isomaltulose, 4 parts of leucine, 1 part of isoleucine, 1 part of valine, 3 parts of gamma-aminobutyric acid, 1.74 parts of arginine, 1.46 parts of 2-oxoglutaric acid, 1.1 to 1.4 parts of taurine, 0.06 to 0.18 part of zinc gluconate and 0.076 to 0.18 part of vitamin E. The solid beverage formula comprises the following components in parts by weight. And 32-64.5 parts of fructo-oligosaccharide, 0.2-10 parts of a sweetening agent and 0.2 part of essence. The feed is comprehensive in nutrition, can quickly supplement water, can keep endurance for a long time, and is suitable for soldiers, athletes and other crowds with high physical exhaustion.
Owner:河北氨健喜生物科技有限公司
Anti-fatigue traditional Chinese medicine composition and application thereof
InactiveCN113143989AImprove exercise enduranceDigestive systemAntinoxious agentsLiver and kidneyRadix Astragali seu Hedysari
The invention discloses an anti-fatigue traditional Chinese medicine composition, which is prepared from the following components in parts by weight: 200 to 400 parts of radix astragali seu hedysari, 100 to 300 parts of radix ginseng, 40 to 80 parts of radix angelicae sinensis and 20 to 60 parts of poria cocos. Various experiments show that the composition can tonify vital energy, warmly tonify liver and kidney, strengthen muscles and bones, regulate water channels and run through vital energy of the body, and can effectively relieve fatigue and improve exercise tolerance of the body.
Owner:ARMY MEDICAL UNIV
A formula and production process of a fruity nutrient drink that increases explosive power
ActiveCN105410548BIncrease contentIncrease flexibilityNatural extract food ingredientsFood ingredient functionsVitamin b6Fruit juice
Owner:FOSHAN SANSHUI JIANLIBAO TRADE
Endurance-enhancing sports solid beverage and preparation method thereof
PendingCN112544847ATo promote metabolismImprove antioxidant capacitySugar food ingredientsInorganic compound food ingredientsBiotechnologyVitamin C
The invention discloses an endurance-enhancing sports solid beverage and a preparation method thereof, the endurance-enhancing sports solid beverage comprises the following components in parts by weight: 11-18 parts of saccharides, 0.05-0.2 part of sodium chloride, 0.01-0.05 part of potassium chloride, 0.0001-0.0003 part of vitamin B1, 0.01-0.025 part of vitamin C and 0.05-0.15 part of taurine, and the preparation method is to mix the components to prepare granules. The solid beverage uses compound saccharides and adds an effective ratio of taurine and vitamins. The saccharides, the electrolyte, the taurine and the vitamins form a synergistic system, so that the solid beverage can quickly replenish water and stabilize the saccharides, maintain the cell activity of organisms, maintain the metabolic capability, improve the antioxidant defense function, delay fatigue and effectively enhance exercise endurance. The preparation method is scientific and simple, and the product is good in taste and easy to carry, brew and drink.
Owner:PEKING UNIV THIRD HOSPITAL
Application of tanshinone IIA or pharmaceutically acceptable salt thereof in improving exercise tolerance of pulmonary vascular disease patients
InactiveCN102961383AImprove activity toleranceLow priceOrganic active ingredientsRespiratory disorderDiseaseVascular disease
The invention discloses application of tanshinone IIA or a pharmaceutically acceptable salt thereof in preparing a medicament for improving the exercise tolerance of pulmonary vascular disease patients. The tanshinone IIA or the pharmaceutically acceptable salt thereof can be used for preparing the medicament for improving the exercise tolerance of the pulmonary vascular disease patients; the tanshinone IIA or the pharmaceutically acceptable salts thereof can be combined with common medicaments for treating the pulmonary vascular diseases clinically at present; and the tanshinone IIA or the pharmaceutically acceptable salt thereof is safe and effective and low in price, and has bright market prospect.
Owner:THE FIRST AFFILIATED HOSPITAL OF GUANGZHOU MEDICAL UNIV (GUANGZHOU RESPIRATORY CENT) +1
Application of 18β-glycyrrhetinic acid in the preparation of products that enhance the body's anti-fatigue ability
ActiveCN112245436BImprove fatigue resistanceOrganic active ingredientsAntinoxious agentsBiotechnologyExercise-induced fatigue
Owner:CHINA AGRI UNIV
Medicine composition for preventing or treating idiopathic diffuse pulmonary fibrosis
InactiveCN109125482AImprove lung functionImprove the quality of lifeRespiratory disorderPlant ingredientsTaraxacum mongolicumIdiopathic pulmonary fibrosis
The invention relates to a medicine composition for preventing or treating idiopathic diffuse pulmonary fibrosis. The medicine composition comprises a lignan compound and a pharmaceutically acceptablecarrier as active ingredients. Preferably, the lignan compound is selected from schisandra chinensis lignan or Mongolian taraxacin A. The medicine composition provided by the invention can be used for the pulmonary fibrosis, particularly the prevention and treatment of the idiopathic diffuse pulmonary fibrosis, and can obviously improve exercise tolerance and pulmonary functions and improve lifequality of a patient.
Owner:WENZHOU MEDICAL UNIV
Application of 18beta-glycyrrhetinic acid in preparation of product for enhancing anti-fatigue capability of organism
ActiveCN112245436AImprove fatigue resistanceOrganic active ingredientsAntinoxious agentsBiotechnologyExercise-induced fatigue
The invention belongs to the field of health foods, and particularly relates to application of 18beta-glycyrrhetinic acid in preparation of a product for enhancing the anti-fatigue capability of an organism. 18beta-glycyrrhetinic acid has the effects of remarkably enhancing exercise tolerance and delaying exercise-induced fatigue. According to the application, the anti-fatigue food component has an effect after being taken for a short time, and can enhance the exercise tolerance of mice, prolong the exercise time and increase the exercise distance when being taken 2.5 hours before exhaustion exercise is started. The application provides a new component for developing anti-fatigue health-care food, and has important application value.
Owner:CHINA AGRI UNIV
Composition for improving exercise tolerance and promoting post-exercise recovery and application thereof
PendingCN114588207AImprove exercise enduranceProlong exhaustive exercise timeOrganic active ingredientsAntinoxious agentsBiotechnologySmoked Plum
The invention belongs to the technical field of traditional Chinese medicine, health care products and functional food, and particularly relates to a composition for improving exercise tolerance and promoting recovery after exercise and application thereof.The composition is prepared from, by weight, 1-3 parts of ginseng, 3-6 parts of smoked plums and 3-6 parts of white granulated sugar, and the composition has the effects of tonifying qi, strengthening the spleen, harmonizing the stomach and promoting salivation. Animal experiments prove that the composition disclosed by the invention can prolong exhaustion exercise time, improve the antioxidant capacity of an organism, relieve damage of oxidative stress to muscles and reduce generation of harmful metabolites. The composition overcomes the defects that in the prior art, a traditional Chinese medicine formula is poor in flavor, or due to the fact that non-medicine-food homologous materials are added, industrial conversion of the technical scheme cannot be achieved, and products cannot be sold on the market or are not suitable for being eaten for a long time.
Owner:GUANGZHOU BAIYUNSHAN JINGXIUTANG PHARM CO LTD
A composition containing Haematococcus pluvialis
ActiveCN103918966BImprove antioxidant capacityIncrease productionFood ingredient functionsOligosaccharide food ingredientsMechanism of actionSaussurea involucrata
The invention relates to a composition containing Haematococcus pluvialis. The composition comprises the following components by weight: 1-40 parts of Haematococcus pluvialis, 1-10 parts of a Saussurea involucrata culture, 10-40 parts of acerola cherry powder and 40-80 parts of oligosaccharide. The composition provided by the invention can improve exercise tolerance and delay fatigue, and the mechanism of action is probably related to increase of the body's SOD content and decrease of the body's MDA content. Also, the composition has exercise tolerance improving and fatigue delaying effects superior to the prior art, and has a synergistic effect.
Owner:BEIJING TONGRENTANG HEALTH PHARMA
Pyruvoyl-based structured ester and preparation method thereof
InactiveCN103497102APromote digestion and absorptionTo promote metabolismOrganic compound preparationCarboxylic acid esters preparationMonoglycerideBiochemical engineering
The invention discloses a pyruvoyl-based structured ester and a preparation method thereof. According to the invention, through the utilization of monoglycerides or diglyceride, and by taking pyruvic acid as a raw material for reaction, a pyruvoyl-based structured ester is synthesized by esterifying. Such compounds not only have the characteristic that long / short-chain structured esters are low in calories, but also have the effects of fat reducing, exercise tolerance increasing and the like; the compounds can be used for overcoming the defects that pyruvate low-level esters are poor in oil solubility and produce peculiar smells, so that the pyruvoyl-based structured ester is a potential functional food.
Owner:SOUTH CHINA UNIV OF TECH
Application of azithromycin in preparing anti-fatigue and anti-disease drug
InactiveCN104997798AExtended swim timeAvoid elevationOrganic active ingredientsAntinoxious agentsDiseasePhysiology
The invention relates to the application of azithromycin in preparing an anti-fatigue and anti-disease drug. The application has the advantages that the anti-fatigue effect of the macrolide antibiotics azithromycin is discovered for the first time; an animal experiment result shows that the azithromycin can significantly prolong the swimming time of a loaded mouse, lower the serum urea ammonia level after strenuous exercise, restrain rising of blood lactic acid, maintain or increase the content of hemoglobin, enhance the activity of lactic dehydrogenase, increase the storage amount of hepatic glycogen and reduce the consumption of hepatic glycogen in exercise and has the significant effects of relieving fatigue and improving exercise tolerance.
Owner:SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
Traditional Chinese medicine for treating coronary heart disease stable angina pectoris complicated with diabetes and hypertension
InactiveCN104922506AMetabolism disorderAluminium/calcium/magnesium active ingredientsAllium macrostemonGastrodia elata
The invention belongs to the technical field of medicines and particularly relates to a traditional Chinese medicine for treating coronary heart disease stable angina pectoris complicated with diabetes and hypertension. The traditional Chinese medicine is prepared from the following raw materials in parts by weight: 8-16 parts of radix bupleuri, 6-14 parts of pericarpium citri reticulatae, 6-14 parts of pericarpium citri reticulatae viride, 6-14 parts of citrus chirocarpus, 6-14 parts of fructus citri, 6-14 parts of allium macrostemon, 4-8 parts of gastrodia elata, 5-13 parts of uncaria rhynchophylla, 5-13 parts of tribulus terrestris, 16-24 parts of gypsum, 5-13 parts of rhizoma anemarrhenae, 8-16 parts of dried rehmannia root, 5-13 parts of radix ophiopogonis, 11-19 parts of polished round-grained rice, 5-13 parts of radix puerariae, 4-8 parts of agastache rugosus, 6-14 parts of ginseng, 11-19 parts of codonopsis pilosula, 11-19 parts of radix pseudostellariae, 8-16 parts of rhizoma atractylodis macrocephalae, 5-13 parts of rhizoma atractylodis, 5-13 parts of pinellia ternate, 5-13 parts of rhizoma arisaematis, 16-24 parts of succus bambusae, 6-14 parts of trichosanthes kirilowii maxim, 5-13 parts of thunberg fritillary bulb, 5-13 parts of ligusticum wallichii, 5-13 parts of rhizoma corydalis, 5-13 parts of radix salviae miltiorrhizae, 5-13 parts of safflower carthamus, 1-5 parts of leech and 4-8 parts of liquorice. The traditional Chinese medicine has the functions of improving exercise tolerance of patients with coronary heart disease, reducing paroxysm frequency of angina, reducing blood sugar and blood pressure, improving living quality of the patients and relieving traditional Chinese medicine syndromes of the patients.
Owner:JINAN BANGWEN MEDICAL TECH
Application of HDAC4 inhibitor in preparing medicine for treating heart failure
ActiveCN108379585AFunction increaseReduced nuclear gene repressionOrganic active ingredientsDisease diagnosisGlycolipid metabolismCase fatality rate
The invention relates to application of HDAC4 inhibitor in preparing medicine for treating heart failure. According to the application, a heart failure animal model after a mouse is died of myocardialinfarction is established, aerobic exercise interference is carried out, cardiac function, energy metabolism and related signal molecules are assessed by using PET / CT, echocardiography and a molecular biological technique, it is found that the aerobic exercise can improve the cardiac function after infarction, increase exercise tolerance, improve mitochondrion structure function and glycolipid metabolism, and reduce the inhibiting effect of myocardium HDAC4 intra-nuclear genes, it is suggested that the DHAC4 is a molecular action target spot for the aerobic exercise to improve the cardiac function after infarction, medicine promoting the phosphorylation of the DHAC4 or reducing the expression of the DHAC4 can be developed, effect same as rehabilitation exercise can be achieved, complianceis improved, thereby improving symptoms, improving exercise tolerance, reducing case fatality rate, and the application has important clinical significance. The application further suggests that thephosphorylation level of the DHAC4 can serve as a marker for cardiac failure prognosis after myocardial infarction.
Owner:ZHONGSHAN HOSPITAL FUDAN UNIV
Method for preparing edible salt water from halite
InactiveCN105876391APreserve the efficacy of health careFull effectFood preparationDiseaseIntestinal tract diseases
The invention provides a method for preparing edible salt water from halite. The method comprises 1, preparing 100 parts by weight of clear water and 80-100 parts by weight of halite and immersing the halite in water for 24h or more so that the salt water is in a fully saturated state after salt dissolution, 2, retaining the halite precipitates, conveying the saturated salt water into a container and uniformly mixing 100 parts by weight of the saturated salt water and 892.76852*10<-6> to 1339.1527*10<-6> parts by weight of potassium iodate. The edible salt water contains iodine, is conducive to prevention of endemic goiter and endemic cretinism, has halite water unique effects of treating tonsillitis, eliminating edema, treating gynecological diseases and relieving arthritis, intestinal tract diseases and chronic bronchitis, and has beneficial effects and health pharmacological effects of improving body basic metabolism, reducing blood sugar, cholesterol and triglyceride, improving exercise tolerance and improving sub-health physique.
Owner:XINJIANG YEXIL MARWAYIT INT COMMERCE & TRADE
Traditional Chinese medicine for treating coronary heart disease stable angina pectoris complicated with diabetes
InactiveCN104922507AMetabolism disorderAluminium/calcium/magnesium active ingredientsTrichosanthes kirilowiiBlood sugar
The invention belongs to the technical field of medicines and particularly relates to a traditional Chinese medicine for treating coronary heart disease stable angina pectoris complicated with diabetes. The traditional Chinese medicine is prepared from the following raw materials in parts by weight: 16-24 parts of gypsum, 5-13 parts of rhizoma anemarrhenae, 8-16 parts of dried rehmannia root, 5-13 parts of radix ophiopogonis, 11-19 parts of polished round-grained rice, 5-13 parts of radix puerariae, 4-8 parts of agastache rugosus, 6-14 parts of ginseng, 11-19 parts of codonopsis pilosula, 11-19 parts of radix pseudostellariae, 8-16 parts of bighead atractylodes rhizome, 5-13 parts of rhizoma atractylodis, 5-13 parts of pinellia ternate, 5-13 parts of rhizoma arisaematis, 16-24 parts of succus bambusae, 6-14 parts of trichosanthes kirilowii maxim, 5-13 parts of thunberg fritillary bulb, 5-13 parts of ligusticum wallichii, 5-13 parts of rhizoma corydalis, 5-13 parts of radix salviae miltiorrhizae, 5-13 parts of safflower carthamus, 1-5 parts of leech and 4-8 parts of liquorice. The traditional Chinese medicine has the functions of improving exercise tolerance of patients with coronary heart disease, reducing paroxysm frequency of angina, reducing blood sugar, improving living quality of the patients and relieving traditional Chinese medicine syndromes of the patients with coronary heart disease stable angina pectoris complicated with diabetes.
Owner:JINAN BANGWEN MEDICAL TECH
Application of hdac4 inhibitor in preparation of medicine for treating heart failure
ActiveCN108379585BFunction increaseReduced nuclear gene repressionOrganic active ingredientsDisease diagnosisGlycolipid metabolismCase fatality rate
Owner:ZHONGSHAN HOSPITAL FUDAN UNIV
Plant salt containing rhizoma anemarrhenae extracts and preparation method thereof
InactiveCN105852034ALower blood lactate concentrationHeart rate recoveryFood scienceGramPantothenic acid
The invention provides plant salt containing rhizoma anemarrhenae extracts. The plant salt is prepared from, by weight, 2-4 parts of rhizoma anemarrhenae extracts and 6-8 parts of Suaeda salsa plant salt. According to the rhizoma anemarrhenae extracts, the rhizoma anemarrhenae total saponin content is 6.5-6.9% and the pantothenic acid content is 17.5-17.8 microgramme per gram. According to the Suaeda salsa plant salt, the flavone content is 2.6-2.7 mg / g, and the Ca content is 2600-2700 mg / kg. The invention further provides a preparation method of the plant salt containing the rhizoma anemarrhenae extracts. The method includes the chromatography step. The prepared plant salt containing the rhizoma anemarrhenae extracts has the functions of reducing after-sports blood lactic acid concentration, facilitating heart rate recovery after sports, improving exercise tolerance and enhancing sports ability, and the extraction rate of pantothenic acid in the rhizoma anemarrhenae extracts is high.
Owner:王胜
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