428 results about "Glyoxal synthesis" patented technology

Compositions comprising a blend of two or more paper strengthening agents have improved stability compared with previously known paper strengthening agents. One component is a polymeric paper strengthening agent, preferably a wet strengthening agent. The other component is a stabilized polyacrylamide prepared by (1) reacting a first portion of glyoxal with a polyacrylamide having pendant amide groups to form a first reaction mixture comprising polyacrylamide; (2) adding an acid to the first reaction mixture to form a second reaction mixture having a reduced pH and comprising the polyacrylamide; and (3) adding a second portion of glyoxal to the second reaction mixture to form the stabilized polyacrylamide. If desired, an aldehyde scavenger can be included in one or more of step (1), step (2), step (3), or the stabilized polyacrylamide. Such compositions can be used to enhance the strength of paper, particularly the wet strength of paper.

Compositions comprising a blend of two or more paper strengthening agents have improved stability compared with previously known paper strengthening agents. One component is a polymeric paper strengthening agent, preferably a wet strengthening agent. The other component is a stabilized glyoxalated polyacrylamide prepared by (1) reacting a first portion of glyoxal with a polyacrylamide having pendant amide groups to form a first reaction mixture comprising glyoxalated polyacrylamide; (2) adding an acid to the first reaction mixture to form a second reaction mixture having a reduced pH and comprising the glyoxalated polyacrylamide; and (3) adding a second portion of glyoxal to the second reaction mixture to form the stabilized glyoxalated polyacrylamide. If desired, an aldehyde scavenger can be included in one or more of step (1), step (2), step (3), or the stabilized glyoxalated polyacrylamide. Such compositions can be used to enhance the strength of paper, particularly the wet strength of paper.

Compositions comprising a blend of two or more paper strengthening agents have improved stability compared with previously known paper strengthening agents. One component is a polymeric paper strengthening agent, preferably a wet strengthening agent. The other component is a stabilized polyacrylamide prepared by (1) reacting a first portion of glyoxal with a polyacrylamide having pendant amide groups to form a first reaction mixture comprising polyacrylamide; (2) adding an acid to the first reaction mixture to form a second reaction mixture having a reduced pH and comprising the polyacrylamide; and (3) adding a second portion of glyoxal to the second reaction mixture to form the stabilized polyacrylamide. If desired, an aldehyde scavenger can be included in one or more of step (1), step (2), step (3), or the stabilized polyacrylamide. Such compositions can be used to enhance the strength of paper, particularly the wet strength of paper.

A polymerizable polymeric photoinitiator according to Formula (I):wherein:PL represents an n+m+p-functional polymeric core;n and m independently represent an integer from 1 to 30;p represents an integer from 0 to 10;o is 0 or 1;INI represents a group selected from the group consisting of a benzophenone, a thioxanthone, a carbazole, a anthraquinone, a camphor quinone, an α-hydroxyalkylphenone, an α-aminoalkylphenone, an acylphosphine oxide, a bisacyl phosphine oxide, an acylphosphine sulfide, a phenyl glyoxalate, a benzoin ether, a benzyl ketal, an α-dialkoxyacetophenone, a carbazolyl-O-acyl-oxime, an α-haloarylketone and an α-haloaryl sulfone;L3 and L4 represent a substituted or unsubstituted divalent linking group comprising 1 to 14 carbon atoms;A represents a radically polymerizable functional group selected from the group consisting of an acrylate, a methacrylate, a styrene, an acryl amide, a methacryl amide, a maleate, a fumarate, an itaconate, an vinyl ether, an allyl ether, an allyl ester, a maleimide, a vinyl nitrile and a vinyl ester; andR4 represents a substituted or unsubstituted alkyl group.Radiation curable compositions containing the polymerizable polymeric photoinitiator and methods for preparing the polymerizable polymeric photoinitiator are also disclosed.

The present invention relates to a fast acting chemical treatment for preventing the generation of hydrogen sulfide odor by the microbial metabolic activities of sulfate reducing bacteria. Specifically, the invention relates to a method for preventing hydrogen sulfide odor generation in a sulfur species-containing aqueous medium, which includes adding to the aqueous medium an effective amount for the purpose of a sulfide scavenger treatment selected from the group consisting of glyoxal, triazine, n-chlorosuccinimide, and mixtures thereof.

A process is disclosed for the production of paper with enhanced dry strength comprising adding to the wet end of a paper machine, (a) a glyoxalated acrylamide-containing polymer and (b) a cationic aqueous dispersion polymer. Guidelines for the properties of the polymers that make this coadditive system effective are established. Polymer properties discussed include molecular weight, cationic charge, polymer composition and functionalization, and relative additive amounts.

The invention relates to crosslinked acid sand fracturing acid liquor, comprising the following components in percentage by weight: 0.7% of thickening agent, 1.5% of cross-linking agent, 1.5% of corrosion inhibitor, 0.5% of surfactant, 0.15% of stabilizing agent, 20% of hydrochloric acid and 75.65% of water, wherein the thickening agent consists of the following components by weight percent: 6.61% of methacrylamidoethyltrimethylamine hydrochloride, 3.22% of acrylamide, 1.25% of acrylic acid, 9.52% of 2-acrylamide-2-methylpropanesulfonic acid, 6.15% of sodium hydroxide and 73.25% of deionized water; and the cross-linking agent consists of the following components in percentage by weight: 1% of zirconium oxychloride, 80% of formaldehyde and 19% of glyoxal. The crosslinked acid sand fracturing acid liquor can be cross-linked in 20% hydrochloric acid, the temperature resistance reaches 100 DEG C, the constant of reaction rate of acid-rock is 1.3744*10-6 (mol / cm<3>)(1-m)*(cm / s), and the viscosity of the gel-breaking liquid is less than 10 mPa.s.

A process is provided of providing glyoxylated polymer additives to a paper making process which brings about improvements in drainage properties of a cellulosic pulp material along with the ability to increase the dry strength of a resulting paper product. The process uses concentrated glyoxal to generate a working solution of a glyoxylated polymer additive which can be generated on site in a paper mill and used within a 24 to 48 hour interval. The ability to glyoxylate polymers in a working solution concentration provides for a more active additive and which can be supplied in a more economical fashion than conventional glyoxylated polymers.

The invention provides a method for preparing 5, 5'-bistetrazole-1, 1'-dioxo hydroxyl ammonium salt (TKX-50), and belongs to the technical field of organic synthesis. The method comprises the steps as follows: step one, glyoxime is prepared, and the yield is 62%; step two, a product obtained in the step one is dissolved in water and concentrated hydrochloric acid, chlorine is introduced at the temperature of 0 DEG C for a reaction for a period of time, and dichloroglyoxime is obtained; and finally, a product obtained in the step two is dissolved in a solvent, and the product and sodium azide have a reaction at the temperature of 0 DEG C for a period of time; after that, the mixture is transferred into diethy ether, and sealed for a reaction at the room temperature overnight after HCl is introduced for a period of time; and after diethyl ether and most HCl gas are volatilized, pH of an aqueous NaOH solution is regulated to be about 8, reflux cooling is performed, filtered and separated solids are dissolved in hydroxylamine hydrochloride to have a reaction for a period of time, and TKX-50 is obtained. According to the method, glyoxal is adopted as a raw material, water is adopted as a solvent for preparation of dichloroglyoxime in the step two, and only direct filtration is required in postprocessing, so that the tedious purification process is prevented, and the cost is reduced; and besides, a target product TKX-50 is synthetized through three steps of reactions, the total yield is up to 34%, the reaction condition is mild, the operation is simple and convenient, and the industrialization is easy to realize.

A rapid method of microwave-assisted formalin fixation of tissue that is described as: (a) a two-step process; (b) applicable to large (>5 mm thick) and small (<5 mm thick) tissues; (c) exposure of fresh tissue (i.e. a surgical biopsy) in a formalin solution to continuous microwave irradiation; (d) formalin circulated and cooled to maintain a constant temperature; (e) microwave-assisted formalin fixation performed at a temperature between 4° C. and 40° C.; (f) a temperature probe used to monitor fixative temperature in the cavity (g) after processing via microwave-assisted formalin fixation, the tissue can be processed by microwave methods or in an automatic tissue processor into paraffin for diagnostic evaluation. The two step process consists of a first low power microwave run followed by a second high power microwave run. An alternate embodiment of the present invention employing a one step MW oven process using other selected fixatives (glyoxal, glyoxal based and other aldehyde fixatives, alcohol, acetone, etc.)

Imidazoles may be manufactured by reacting a glyoxal, ammonia, an aldehyde, and optionally a primary amine, in the presence of a Bronsted acid whose pKa is approximately equal to the pKa of the ammonium cation of the primary amine, or if the primary amine is not present, to the pKa of the ammonium (NH4+) cation. The reaction may be used to make in relatively high yields a wide variety of imidazoles using relatively inexpensive starting materials. The imidazoles are useful as chemical intermediates.

The invention relates to a preparation method and application of a formaldehyde fluorescent probe, and belongs to the technical field of analytical chemistry. The formaldehyde fluorescent probe is a ratio-type fluorescent probe with double emission bands. The excitation wavelength is 318 nm; and the fluorescence peak at 359nm decreases gradually with the increasing of the concentration of formaldehyde, and at the same time a new emission band is produced at 451 nm and the fluorescence peak gradually increases. The formaldehyde fluorescent probe can resist the interference of acetaldehyde, glyoxal, methylglyoxal, benzaldehyde, alanine, glycine, serine, arginine, cysteine, glutathione and glucose, has high detection accuracy, high sensitivity and strong anti-interference capability. In addition, the formaldehyde fluorescent probe of the invention can detect the formaldehyde in a biological sample (cell environment), realizes formaldehyde fluorescence imaging in living cell level, and has potential practical application value. The synthesis of the formaldehyde fluorescent probe only needs a one-step reaction, which is simple and high in yield.

The invention discloses a novel formaldehydeless permanent press finishing agent for a fabric and a preparation method and application thereof. The formaldehydeless permanent press finishing agent for the fabric is prepared by performing a polymerization reaction on acrylamide, glyoxal, phthalic anhydride, sulfuric acid, potassium persulfate and the like. The product of the invention is mainly used for performing noniron finish on the fabric and improving the firmness of a dyed fabric and a printed fabric. Compared with the conventional N-methylol acrylamide resin, the permanent press finishing agent has prominent advantages of excluding of formaldehyde and crease resilience equivalent to or surpassing those of etherfied 2D (etherfied dimethylol dihydroxy ethylene urea) after being used for finishing a cotton fabric; and compared with the conventional formaldehydeless resin, the agent has the advantages of high crease resilience, strength loss less than that of a polycarboxylic formaldehydeless resin, cost lower than those of dimethylol dihydroxy ethylene urea (DMeDHEU) and butanetetracarboxylic acid (BTCA) and cost performance far higher than that of a polycarboxylic resin.

The invention relates to fluorescent probe detection, in particular to a derivative L of rhodamine B, preparation thereof and use thereof. The derivative L of the rhodamine B has a structural formula (I). The preparation method of the derivative L of the rhodamine B comprises: firstly, reacting the product of the hydrazinolysis of the rhodamine B with glyoxal to obtain an intermediate compound; and secondly, reacting the intermediate compound with benzyldithiocarbazate in a molar ratio of 1:1 in absolute ethanol under a refluxing condition for 4 to 6 hours, cooling, filtering precipitated solid, washing with absolute ethanol and ethyl ether in turn and drying under vacuum to obtain a target compound. The derivative L of rhodamine B can serve as a fluorescent probe. In the invention, the derivative L of rhodamine B is obtained by an effective synthesis means, the copper ion selectivity is high, and the detection of copper ions can be realized on the basis of optimized experimental conditions.

This invention relates to compounds of formula (I) which are glyoxalase I inhibitors, pharmaceutical salts or compositions comprising such compounds, and the use of such compositions and compounds to treat various conditions alleviated by the inhibition of glyoxalase 1. Wherein X is N or CH. R2 is H, CF3; or optionally substituted C5-6 aryl, C3-7 cycloalkyl, C5-7 heterocyclyl. R3 is H; or optionally substituted C5-6 aryl, C3-7 cycloalkyl, C5-7 heterocyclyl. Alternatively R2 and R3 together form an optionally substituted C3-4alkylene group wherein L3 and L4 are single bonds thus forming a C5-6 ring fused with the aromatic ring to which L3 and L4 are attached. L3 and L4 are independently selected from a single bond, optionally substituted C1-4 alkylene, -L9YN(OH)C(═O)L10- and -L9C(═O)N(OH)YL10-, wherein L9 and L10 are independently selected from optionally substituted C1-4 alkylene, C5-6 arylene, C1-4 alkylene-C5-6arylene and a single bond, wherein Y is NH or a single bond.

The invention provides a resin finishing agent composition for purified cotton clothes and a preparing method thereof. The resin finishing agent composition is a multi-ingredient resin finishing agent prepared by using etherified modified glyoxal resin, vinol, a polyethylene softener, an organic siloxane softener, MgCl2.6H2O, water and the like as main parts. The resin finishing agent composition is used in three-dimensional cat whisker crumpling finishing of pure cotton clothes. Compared with the conventional resin finishing agent, the resin finishing agent composition of the invention simplifies production technology and reduces operation and technology difficulties; and after finishing, fabrics have strength retention of 65-75%, a wrinkle recover angle (WRA / degree) is greater than 254 degrees, and the cat whisker three-dimensional retention effect reaches four to five level.

The invention relates to a synthesis method for catalytic oxygen oxidation of glyoxal aqueous solution to glyoxalic acid aqueous solution with nitrogen oxide, which belongs to the field of the chemical synthesis technology. The catalyst used in the method is exhausted nitrogen oxide gas in industrial production, the oxidizer is cheap industrial oxygen, and the product need only be cooled and crystallized for removing oxalic acid.

Polyboronic compounds useful as delayed crosslinking agents may be produced by using a polyamine as base scaffold and incorporating boron via reaction with intermediate borates which may be formed in the condensation reaction between boric acid and a diol. A di-aldehyde, such as glyoxal, may be introduced following caustic treatment of the reaction mixture of polyaminoboronate to form the polyboronic compound.

The invention relates to a synthesis method of non-formaldehyde easy-care finishing resin of textile. The synthesis method comprises the following steps: glyoxal is reacted with an ureido compound under a condition with the existence of a buffering agent and a complex, a pH value of 4 to 8 and the temperature of 20 DEG C to 70 DEG C for 3h to 6h so as to obtain unetherified non-formaldehyde easy-care finishing resin; the complex is added at the beginning of or in the process of the synthesis reaction between glyoxal and the a ureido compound; and the buffering agent is one of citric acid / citrate, citric acid / acetate, tartaric acid / tartarate, salicylic acid / salicylate, phthalic acid / phthalate and alkali phosphates and the complex is organic carboxylic acid or organic carboxylate and the like with a molecular weight of 190 to 420. The non-formaldehyde easy-care finishing resin prepared by the method has higher purity and lower content of remnant glyoxal, has good effect as a textile finishing agent and does not release formaldehyde in the finishing and use of textile.

The present invention is directed to a method for preparing a cellulose reactive adduct of polyvinylamide and a composition resulting from the method. The preparation of the cellulose reactive adduct is carried out close to a Critical Concentration defined herein. When the reaction is run close to this Critical Concentration, the risk of gelation is minimized, consumed glyoxal is maximized, and shelf live is enhanced. Additionally, the glyoxalated vinylamides of the present invention impart improved wet and dry strengthening efficiency to paper and paperboard when compared to adducts disclosedin previously described art.

The invention discloses a MAX-DOAS based vertical profile inversion algorithm used for measuring aerosol and trace quantity pollution gas. According to the MAX-DOAS based vertical profile inversion algorithm used for measuring aerosol and trace quantity pollution gas, Lambert-Beer's law is adopted, QDOAS is adopted for calculating ultraviolet wave band and visible wave band O4 difference slant column intensity, and difference slant column intensities of trace quality gas including nitrogen dioxide, sulfur dioxide, formaldehyde, nitrous acid, and glyoxal; different wave band O4 DSCD inversion of corresponding wave band aerosol profile is carried out; the aerosol optical thickness obtained through inversion and real aerosol optical thickness measured using a sun photometer are extracted andcompared, and the hour average result of trace quality gas profile bottom layer concentration is extracted, and is compared with nationally controlled station ground corresponding gas concentration. The MAX-DOAS based vertical profile inversion algorithm is used for solving foundation passive remote sensing observation vertical profile inversion algorithm problems, realizing rapid, continuous, high efficiency monitoring on atmosphere aerosol and polluted gas space-time change characteristics, and satisfying requirements on environment pollution study and monitoring.

The invention relates to a formaldehyde fluorescence probe and a preparation method and an application thereof, and belongs to the technical field of preparation of formaldehyde probes. The formaldehyde fluorescence probe has the structural formula defined in the specification; the formaldehyde response time is about 10 seconds, and thus rapid detection is realized; the formaldehyde fluorescence probe can resist interference of acetaldehyde, glyoxal, methylglyoxal, benzaldehyde, alanine, glycine, serine, arginine, cysteine, glutathione, glucose, hydrogen peroxide and hypochlorous acid and has good specificity. The formaldehyde content in a solution can be determined through observing the change degree of spectra in a fluorescence spectrophotometer, and thus quantitative detection is achieved; the lower limit of detection is 7.7*10<-7> mol / L. Whether the solution contains formaldehyde and the general concentration of formaldehyde are determined through observing color changes of the solution via naked eyes. In addition, with use of the probe II, detection of formaldehyde in biological samples can be realized. The preparation method of the probe II is simple, and the yield is relatively high.

The present invention provides one kind of paper product adhesive with low cost, high strength and fast drying and its preparation process. The present invention features that the paper product adhesive is produced with PVA, starch, acrylic acid, urea, glyoxal and other materials in certain weight proportion, and through certain reaction. The paper product adhesive features its fast drying speed, low cost and high strength, possesses certain water resistance and moisture-proof performance. It has the advantages of acrylate adhesive, white latex adhesive and starch glue, and is used in producing honeycomb card board, paper pipe, paper box, paper box and other paper products.

A high-antibacterial-performance and high-wear-resistance TPE (thermal plastic elastomers) shock-absorption kneecap is prepared from the following raw materials in part by weight: 100 parts of MAH-g-SEBS, 40-50 parts of MAH-g-PP, 5-15 parts of glyoxal modified chitosan-amino-terminated hyperbranched polyamide-amine complexes, 1-5 parts of chitosan-beta cyclodextrin modified nanometer tio2 and 0.5-2 parts of zirconia ceramic microbeads. The TPE shock-absorption kneecap is excellent in shock absorbing property, high in strength, high in wear resistance and high in antibacterial performance, and a user feels comfortable when using the kneecap.

The present invention pertains to substances of the formula (I) wherein X is O or S; and R1-R4 are defined in the claims as inhibitors of glyoxalase I and / or II, pharmaceutical compositions comprising one or more compounds according to formula (I) and the use of one or more compounds according to formula (I) for the treatment of diseases associated with increased glycolytic metabolism. In one embodiment, the disease is a fungal infection.

This invention provides compositions and methods for fixing a biological sample, particularly fecal samples for diagnosis of parasitic infection. The fixative composition of the present invention comprises glyoxal (pyruvate aldehyde) and zinc sulfate and permits staining of biological samples without use of toxic compounds, such as formaldehyde and mercury-containing compounds. The fixative is compatible with many diagnostic assays, including trichrome stains, hematoxlin, ELISA, fluorescent assays, and lateral flow assays.

The invention provides a formula and a production process method for a derusting cleaning liquid used for surface treatment of metal. The formula comprises a first formula and a second formula, wherein the first formula comprises the following components in percentage by weight: 17 to 22 percent of 35-percent hydrochloric acid, 2 to 4 percent of 36-percent acetic acid, 1.5 to 3 percent of glyoxal,0.5 to 1 percent of sodium chloride, 10 to 20 percent of water; and the second formula comprises the following components in percentage by weight: 17 to 22 percent of 35-percent hydrochloric acid, 13to 18 percent of 60-percent formic acid, 1.5 to 3 percent of glyoxal, 0.5 to 1 percent of sodium chloride, 10 to 20 percent of water. The production process comprises the following steps of: adding the glyoxal and the sodium chloride into the acetic acid and the water (or the formic acid and the water) respectively, and evenly stirring the mixing solutions to obtain two types of mixing solutions;and adding the hydrochloric acid into the two types of mixing solutions respectively, and evenly stirring to obtain the finished productions of two types of products. The formula has the advantages of strong derusting ability, high derusting speed, uniform and quick removal of rust and concrete on steel and copper materials, safe and convenient production and use, and low cost.

The present invention relates to methods and compositions for modifying, isolating, detecting, visualizing, and quantifying citrulline and / or homocitrulline-containing peptides, polypeptides, and proteins using mono- and disubstituted glyoxal derivatives. The invention also provides kits for modifying, isolating, detecting, visualizing, and quantifying the relative amounts of citrulline and / or homocitrulline-containing peptides, polypeptides, or proteins in solutions or samples.

The present invention relates to a fast acting chemical treatment for preventing the generation of hydrogen sulfide odor by the microbial metabolic activities of sulfate reducing bacteria. Specifically, the invention relates to a method for preventing hydrogen sulfide odor generation in a sulfur species-containing aqueous medium, which includes adding to the aqueous medium an effective amount for the purpose of a sulfide scavenger treatment selected from the group consisting of glyoxal, triazine, n-chlorosuccinimide, and mixtures thereof.

The invention discloses a preparation method of a retanned intumescent flame retardant, which comprises the following steps: adding a catalyst into dimethyl phosphite, evenly mixing, adding acrylamide, acrylonitrile and maleic anhydride for reaction, and obtaining colorless transparent liquid A; using alkaline solution for regulating the pH of the transparent liquid A to 5-7, dripping glyoxal, and carrying out reaction for obtaining light yellow liquid B; and adding melamine into the light yellow liquid B for reaction, and obtaining reddish brown retanned intumescent flame retardant C. A product synthesized by the preparation method not only has good flame resistance, which can lead leather to achieve the difficult-flammability by adding 3% of the weight of the leather of the product, but also has good compatibility with the leather, thereby improving the hand feel, the fullness, the softness and the mechanical performances of the leather.