Dendritic polymers with enhanced amplification and interior functionality are disclosed. These
dendritic polymers are made by use of fast, reactive ring-opening
chemistry (or other fast reactions) combined with the use of
branch cell reagents in a controlled way to rapidly and precisely build dendritic structures, generation by generation, with cleaner
chemistry, often single products, lower excesses of reagents, lower levels of
dilution, higher capacity method, more easily scaled to commercial dimensions, new ranges of materials, and lower cost. The dendritic compositions prepared have novel internal functionality, greater stability (e.g.,
thermal stability and less or no reverse Michael's reaction), and reach encapsulation surface densities at lower generations. Unexpectedly, these reactions of polyfunctional
branch cell reagents with polyfunctional cores do not create cross-linked materials. Such
dendritic polymers are useful as demulsifiers for oil / water emulsions,
wet strength agents in the manufacture of paper,
proton scavengers, polymers, nanoscale monomers, calibration standards for
electron microscopy, making
size selective membranes, and agents for modifying
viscosity in aqueous formulations such as paint. When these
dendritic polymers have a carried material associated with their surface and / or interior, then these dendritic polymers have additional properties for carrying materials due to the unique characteristics of the dendritic
polymer, such as for
drug delivery,
transfection, and diagnostics.