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49results about How to "Strong pharmacological effect" patented technology

Chinese medicinal ointment with antibacterial and antipruritic effects and preparation method thereof

The invention discloses a Chinese medicinal ointment with antibacterial and antipruritic effects and a preparation method thereof. The Chinese medicinal ointment comprises the following raw materials: amur corktree bark, lightyellow sophora root, common ducksmeat herb, aloe, argy wormwood leaf, fineleaf schizonepeta herb, borneol and the like. The invention also discloses a preparation method forthe Chinese medicinal ointment, which comprises the following steps: preparing a water phase from the amur corktree bark, the lightyellow sophora root, the common ducksmeat herb and the aloe; collecting volatile oil from the argy wormwood leaf and the fineleaf schizonepeta herb; grinding the borneol into fine powder; preparing an oil phase from cetyl alcohol, vaseline and glycerin; and preparing the ointment by normal working procedures. When the Chinese medicinal ointment is prepared, a water decoction heat filter method and a steam distillation method are respectively adopted to make effective medicaments give full play. When used, the Chinese medicinal ointment has the characteristics that the medicaments are directly acted on disease positions; and the response is quick. The ointment of the invention has good antibacterial, anti-inflammatory and antipruritic effects and is in a dose-response relationship. The long-term toxicity research proves that the Chinese medicinal ointment is safe.
Owner:CHENGDU YONGKANG PHARM CO LTD

Use of low-molecular weight oligomannuronate in preparation of drug or health care product for preventing or treating Parkinson's disease

ActiveCN103405468AInhibition of intracellular expressionInhibition of deposition in vitroOrganic active ingredientsNervous disorderSide effectNatural product
The invention provides a use of low-molecular weight oligomannuronate in preparation of a drug or a health care product for preventing or treating Parkinson's disease. According to the invention, marine acidic polysaccharose as a raw material is prepared into a water-soluble low-molecular weight mannuronic acid compound. An experiment proves that the low-molecular weight mannuronic acid can be used for preventing and treating or improving Parkinson's disease, has obvious pharmacological effects and no toxic or side effects on nerve cells and can be taken for a long time. The low-molecular weight mannuronic acid is a marine natural product, has the advantages of rich resources, easy industrialization, high safety, unique structure and good oral absorption, and has a wide market application prospect in prevention and treatment of Parkinson's disease.
Owner:OCEAN UNIV OF CHINA

Achyranthes bidentata polypeptide, preparing process and uses

The present invention discloses achyranthes bidentata polypeptide, a production method and applications, and the achyranthes bidentata polypeptide is produced with the steps including polypeptide extraction, polypeptide separation, etc. The achyranthes bidentata polypeptide is used to the preparation of drugs and health products for treating peripheral nerve injuries, cerebrovascular accidents, ischemic brain injuries, cerebral traumas, optic nerve injuries, spinal cord injuries and central nervous system injuries, antiaging and preventing neurodegenerative diseases. Experiments prove that the extracted achyranthes bidentata polypeptide (protein) of the present invention has the effects of promoting the growth of nerves, preventing the fading of nerve cells and promoting the regeneration of injured nerves, the source of medicinal materials is single, the preparation method is advanced, the technique is reasonable, the ingredients of preparations are definite, safety is high, and pharmacological action is obvious.
Owner:NANTONG UNIVERSITY

Coix seed wine

The invention relates to a kind of medical wine that possesses functions of excreting dampness, eliminating arthralgia syndrome, apocenosis and invigorating the spleed and strengthening the middle-warmer energy. It mainly takes coix seed as raw material, and the effect for treating dropsy, asthma, lung abscess, nephritis, nephropyeltis, beriberi, dysuria, arthritis with muscle contracture, diarrhea of deficiency type, acute pharyngitis and flat wart is distinctive. The product can be used as normal health- care beverage, which is non side effect, and possesses good economic and social benefit.
Owner:FANGXIA ENTERPRISE INFORMATION CONSULTING WUJIANG

Externally used medicament for curing rheumatism cold ache disease

The invention discloses a medicine which is externally used for treating rheumatic coldness and pains. The invention is characterized in that the invention is prepared by the following medicines by weight: spatholobus stem of 65 to 90g, clematis chinensis of 30 to 50g, brassica alba boiss of 36 to 76g, phellodendron amurense of 28 to 47g, caulis sinomenii of 20 to 50g, raw wild aconite of 37 to 68g, raw radix aconite of 37 to 68g, large centipede of 10 to 20 in quantity, honeylocust thorn of 60 to 80g, thunder god vine of 50 to 70g, salicylic acid of 30 to 50g, phryma leptostachya of 65 to 100g, menispermaceae of 40 to 60g, ephedra of 45 to 80g, parsnip of 35 to 60g, cinnamon of 20 to 40g, notopterygium root of 20 to 40g, heracleum hemsleyanum michaux of 20 to 45g, toad venom of 18 to 25g, himalayan teasel root of 50 to 80g, angelica of 30 to 54g, radix astragali of 30 to 54g, franklincense of 41 to 59g, myrrh of 41 to 59g, rhizona gastrodiae of 25 to 35g, pilose antler of 30 to 50g, borneol of 30 to 40g, muskiness of 8 to 15g, chili of 70 to 110g, radix aconiti brachypodi of 60 to 70g and mandragora of 40 to 68g.
Owner:彭科林

Resin adsorption process for preparing tannin from sea-buckthorn leaf

The invention relates to a process for preparing tannin from sea-buckthorn leaves through resin adsorption method which comprises the steps of, (1) extracting sea-buckthorn leaves using 40-95% ethanol aqueous solution as dissolvent at the temperature of 20-90 deg.C, combining the extract liquid, filtering the reclaimed ethanol, obtaining extract liquid by centrifugation, (2) going through the disposed large hole adsorption resin tower, (3) water scrubbing until the driving off liquid becomes colorless, elution and reclaiming ethanol, vacuum drying to obtain brown to light brown extract. The invention realizes simple process thus can be applied in mass production.
Owner:河北神兴沙棘研究院

Composition for improving memory and brain health conditions of patients with Alzheimer disease

The invention discloses a composition for improving memory and brain health conditions of patients with Alzheimer disease, which is invented for treating Alzheimer disease. The composition is prepared from DHA alga oil composite powder, glutamine, asparagine, soyabean lecithin, taurine, panaxoside, gingko leaf extract, arachidonate grease composite powder, tea polyphenol, raw ginger, selenium-enriched yeast and starch. The prescription is used for supplying the cerebral neuron main structure caused by senescence or various changes by extremely targeted enhancement and adjustment for nutrition metabolism of cerebral neuron, starting with improving the nutrition state and activity of cerebral neuron and improving the metabolism system for cerebral blood and nutrition transmission, from the view of nutriology according to the physiological characteristics of the human brain. According to the composition, toxic and side effects and possible adverse results generated by certain chemical drugs and certain traditional Chinese medicinal materials can be overcome, the defect of poor medical non-nutritional rehabilitation durability can be avoided, and the frequency of relapse can be reduced.
Owner:宋妮

Composition with function of aiding to reduce blood fat and preparation method of composition

The invention discloses a composition with the function of aiding to reduce blood fat, and a preparation method of the composition. The composition comprises the components in parts by weight: 1-12 parts of rhizoma curcumae longae, 1-9 parts of red yeast rice, 1-7 parts of longstamen onion bulb, 3-8 parts of lotus leaves, 2-7 parts of hawthorns, 2-10 parts of rhizoma alismatis, 1-12 parts of semen cassiae and 3-7 parts of polygonum multiflorum. The composition with the function of aiding to reduce blood fat has obvious pharmacologic action for the cardiovascular system, and is capable of well reducing cholesterol and comprehensively adjusting blood lipid metabolism.
Owner:HUBEI HONGYUAN PHARMA

Hard cream candy for refreshing and restoring consciousness and preparing method thereof

InactiveCN105707394AStrong pharmacological effectHas a refreshing and brain-building effectConfectionerySweetmeatsFood additiveMaltitol
The invention provides hard cream candy for refreshing and restoring consciousness and relates to the technical field of candy. The candy is prepared from 60-80 parts of condensed milk, 25-35 parts of white granulated sugar, 20-30 parts of cream, 3-5 parts of edible salt, 2-4 parts of edible essence, 3-5 parts of food additives, 15-25 parts of maltitol, 20-30 parts of xylitol, 6-8 parts of composite microelements, 2-4 parts of radix angelica sinensis, 2-4 parts of the root of kudzu vine, 1-3 parts of liquorice roots, 2-4 parts of saffron, 1-3 parts of chrysanthemum morofolium ramat, 2-4 parts of rhizoma gastrodiae, 2-4 parts of uncaria rhynchophylla, 1-3 parts of mint, 2-4 parts of radix angelica sinensis, 2-4 parts of milkvetch roots and 3-5 parts of radix ophiopogonis. The candy has the advantages that the formula is reasonable, the preparing method is simple, after the prepared hard candy is eaten, the thought can become agile and clear, energy metabolism is promoted, it is ensured that energy is supplemented constantly, vigor is increased, and the candy is good in taste and suitable for any people to eat.
Owner:周利

Method for breeding chickens without using antibiotics

The invention discloses a method for breeding chickens without using antibiotics. The method comprises the following steps: (1) building a free range; (2) building a henroost; (3) adding 0.05 to 0.1 weight percent of photosynthetic bacteria powder and 0.1 to 0.2 weight percent of chlorella pyrenoidosa powder into basic food; (4) adding 0.5 to 1.0 weight percent of a mixture of chitooligo saccharide powder, aronia melanocarpa powder and the chlorella pyrenoidosa powder into drinking water to implement biotrophic immunity for the chickens; (5) disinfecting a chicken house. According to the method, no antibiotics are used, so that the problem of residual antibiotics caused by delay of time of antibiotics excretion from a chicken body due to the use of a large amount of the antibiotics in theprior art is solved. Meanwhile, the survival rate of the chickens bred by using the method is higher, and the average egg production rate of the chickens is also increased substantially.
Owner:武春风

Application of notoginseng saponins Rg 1 in preparing medicine for treating pulmonary interstitial fibrosis

The invention provides an application of notoginseng saponins Rg 1 in preparing medicine for treating pulmonary interstitial fibrosis. Pharmacological experiments show that if in vitro, the notoginseng saponins Rg 1 can inhibit the activity of human embryonic lung fibroblast and has good dose-dependent; if in vivo, the notoginseng saponins Rg 1 can decrease the lung coefficientand the lung hydroxyproline content of a mouse with pulmonary interstitial fibrosis; the notoginseng saponins Rg 1 can also reduce the pulmonary alveolitis and the degree of pulmonary interstitial fibrosis of the mouse with pulmonary interstitial fibrosis; the raw materials of the notoginseng saponins Rg 1 are easy to obtain, and can be prepared into various common dosage forms such as tablets, capsules, and injections; and the preparation method is simple.
Owner:XINXIANG MEDICAL UNIV

Turmeric pigment composition and method for preparing same

ActiveCN102686676AGood dispersionExcellent absorption in the bodyPowder deliveryNatural dyesSolventAqueous solution
Disclosed is a turmeric (Curcuma longa L.) pigment composition. Specifically disclosed is a turmeric pigment composition, by which the aggregation or sedimentation of turmeric pigment over time can be effectively prevented even in the case of adding turmeric pigment to a solvent to give a high content and which exhibits good color development and enables clear and stable coloring in a light color tone that cannot be achieved by the conventional techniques. Also disclosed is a method for preparing the turmeric pigment composition. The turmeric pigment composition is prepared by adding turmeric pigment to an aqueous solution containing ghatti gum and then grinding the turmeric pigment in the solution until the average particle diameter thereof falls 1 [mu]m or below.
Owner:SAN EI GEN F F I

Ketoprofen-containing poultice

Provided is a poultice provided with a support and an ointment layer on top of the support, wherein the ointment layer contains 1.5-2.5 mass% of ketoprofen, 1.5-2.5 mass% of 4-tert-butyl-4'-methoxydibenzoylmethane, and 12-18 mass% of propylene glycol based on the total mass of the ointment layer.
Owner:HISAMITSU PHARM CO INC

Red barberry distilled liquor and making method thereof

The invention discloses a red barberry distilled liquor and a making method thereof. Firstly, 20-30parts by weight of warm boiled water is added into 2.0-3.0 partsby weight of yeast for fermentation, and then yeast foam liquid is formed; then, 10000-12000 parts by weight of red bayberry juice and 1000-1200 partsby weight of sugar are added into the yeast foam liquid, the mixture is sealed to be fermented after being stirred, temperature is controlled to 20-35 DEG C, and fermentation time is 3-4 months; clarifying is performed, and the red bayberry fermented wine with the alcoholic strength being 12-15 is brewed, and finally the red barberry distilled liquor with the alcoholic strength being 50-65 is made through distillation treatment. The red barberry distilled liquor has the smooth, coordinating and harmonious fruit wine aroma. The sugar degree of the red barberry distilled liquor is low, the alcoholic strength of the red barberry distilled liquor is high, the red barberry distilled liquor has a good pharmacological action, and the red barberry distilled liquor can wash the intestines and stomach and make the five internal organs harmonious, has the diuretic effect, can benefit the kidneys and strength the spleen, and has the functions of resisting aging, beautifying faces and improving human body immunity. Requirements of different customers can be met easily.
Owner:林福宽

Plateau scented tea processing and making method

The invention discloses a plateau scented tea processing and making method. The method comprises the steps of picking tea leaves, drying the tea leaves in the sun, rolling the tea leaves, drying the tea leaves, cooling the tea leaves, choosing flower materials, cooling the flower materials in the air, conducting first-stage scenting, second-stage scenting and third-stage scenting, drying the tea leaves with sufficient fire, conducting packaging and the like. According to the plateau scented tea processing and making method, the characteristics of plateau tea are rationally utilized for deep processing, and processed scented tea maintains rich and refreshing tea flavor and has a fresh and lovely fragrance of flowers. A user brewing and sucking the plateau scented tea will smell the fragrance of flowers, taste the sweetness all mouth and feel relaxed and happy. The plateau scented tea reserves the effects of tea, and the fragrance of flowers also has a good pharmacological action, so that the plateau scented tea is beneficial to human health and has the effects of discharging waste produced in a human body over night, regulating circulation of intestines and stomach, expelling toxin and the like.
Owner:贵州省凤冈县浪竹有机茶业有限公司

Herb tea composition with health function and preparation method of herb tea composition

The invention discloses a herb tea composition with a health function and a preparation method of the herb tea composition, and belongs to the field of health beverages. The herb tea composition with the health function comprises the flowing raw materials in parts by weight: 1.5 parts to 2 parts of black Chinese wolfberries, 1.5 parts to 2 parts of radix ophiopogonis, 1.5 parts to 2 parts of bamboo leaves, 0.5 part to 2 parts of jasmine scented tea, 1 part to 1.5 parts of mint leaves, 1 part to 1.5 parts of honeysuckle flowers, 1 part to 1.5 parts of germinated millet, 0.5 part to 0.8 part of semen oroxyli, 1 part to 1.5 parts of herba epimedii and 1.5 parts to 2.5 parts of fried semen cassiae. The preparation method is easy and easy to operate, the immunity can be obviously enhanced, the body circulation can be improved, and the effects of improving the enterogastric circulation, relaxing bowel, clearing liver and improving vision and expelling toxin for beautifying are achieved.
Owner:南昌花朵朵生物科技有限公司

Application of Euparin in preparing medicine for treating ischemic cardiovascular and cerebrovascular diseases

The invention provides an application of Euparin in preparing a medicine for treating ischemic cardiovascular and cerebrovascular diseases. According to the pharmacological experiments, the mouth open breathing time of a mouse after decapitation can be prolonged obviously by Euparin, the moisture content of brain tissue after cerebral ischemia can be reduced remarkably; MDA (methylene dioxyamphetamine) content of brain tissue of a forebrain ischemia mouse can be reduced and the SOD (superoxide dismutase) content can be elevated; the unfavorable mouse memory acquisition due to scopolamine can be alleviated; the raw materials for preparing Euparin are easy to get, the Euparin can be prepared into various normal dosage forms such as tablets, capsules and injections through normal methods and the preparing method is simple.
Owner:XI AN JIAOTONG UNIV

Application of 20 (R)-ginsenoside Rg3 in preparing medicine for preventing and/or treating obesity and medicine

The invention discloses a novel application of 20 (R)-ginsenoside Rg3 in preparing a medicine for preventing and / or treating obesity. Tests prove that the 20 (R)-ginsenoside Rg3 is significant in curative effect on treating the obesity, rapid to take effect and low in toxic and side effects; and the 20 (R)-ginsenoside Rg3, as an obesity-treating medicine, which is safe, efficient, stable and simple in preparation process, is applicable to industrial production and is easy for popularization. The invention provides a novel medicine source for preventing and treating the obesity and complications thereof.
Owner:富力

Blueberry beverage and preparation method thereof

The present invention relates to the technical field of beverages and productions thereof, and particularly a blueberry beverage and a preparation method thereof. The blueberry beverage consists of the following raw materials in parts by weight: 300-600 parts of blueberry raw juice, 3-10 parts of stevioside, 100-400 parts of siraidia grosvenorii fruit juice, 1-5 parts of citric acid, and 3-5 parts of fruit material suspending agent. The blueberry beverage has efficacies of preventing oxidation, preventing aging, beautifying features and nourishing skins, improving eyesight, preventing cranial nerve aging, preventing cancer, softening blood vessels, enhancing human body immunity, promoting salivation and quenching thirst, and moistening intestines and relaxing bowels, and can also be drunk by people with high blood pressure, high blood lipids and diabetes.
Owner:DUOCAIMIAOBAO GUIZHOU PHARMA CO LTD

Application of adenanthin in pharmacy

InactiveCN102462677AGood preventive and curative effectStrong pharmacological effectNervous disorderEster active ingredientsAdenanthinLow toxicity
The invention discloses an application of adenanthin in preparing medicines for preventing or treating multiple sclerosis, and an NF-kB inhibitor which is adenanthin. The adenanthin disclosed herein is safe, has low toxicity, and has strong pharmacological action and good medicinal foreground. The adenanthin active substance has the advantages of easy absorption, good stability, and the like, and is suitable for being as an additive of novel medicament, food, health products and / or meals for development.
Owner:SHANGHAI JIAOTONG UNIV SCHOOL OF MEDICINE +1

Preparation method and purpose of total phenolic acid in pithecellobium clypearia

The invention provides a preparation method of total phenolic acid in a plant pithecellobium clypearia. The preparation method comprises the steps of crushing a pithecellobium clypearia raw material, extracting with pure water, condensing to form concrete, suspending with water, then putting on macroporous resin, eluting with acid water, removing water-soluble impurities, allowing phenolic acid substances to be maintained on the macroporous resin, eluting with a water-alcohol system to form a total phenolic acid extract which is also an effective part with pharmacological activity in the pithecellobium clypearia. The total phenolic acid in the pithecellobium clypearia has obvious antineoplastic activity, the pithecellobium clypearia, as traditional Chinese medicine, has lower toxic and side effects, and a new anti-tumor drug can be developed. The total phenolic acid in the pithecellobium clypearia can be prepared into various oral preparations. The method is reasonable in design and has the characteristics of simple technical process, low cost, low energy consumption and low pollution in a production process.
Owner:SHENYANG PHARMA UNIVERSITY +1

Application of forsythiaside A in preparation of drugs for preventing and treating cardiovascular and cerebrovascular diseases

The invention proves that forsythiaside A has the function of inhibiting platelet aggregation and simultaneously has the obvious anticoagulation role by studying the impacts of the forsythiaside A on ADP-induced platelet aggregation in vitro of rats, the impacts on plasma prothrombin time (PT) of the rats and the impacts on plasma thrombin time (TT) of the rats. The forsythiaside A can be used for preparing drugs for preventing and treating cardiovascular and cerebrovascular diseases. The forsythiaside A can also be used as a food additive for preparing functional foods for preventing and treating the cardiovascular and cerebrovascular diseases.
Owner:山西华卫药业有限公司

Grape planting method capable of reducing heavy metal content

The invention relates to the technical field of grape planting, and particularly discloses a grape planting method capable of reducing the heavy metal content. The method includes the following stepsof (1) planting land treatment; (2) drainage system construction; (3) seedling culture; (4) transplanting; (5) seedling checking and gap filling; (6) support erection; (7) weeding and fertilizing; (8)pest and disease control; (9) field drainage; (10) pruning; (11) harvesting. The planting method has the advantages that land selection is scientific, base fertilizer application and top applicationare reasonable, the absorption of grapes is facilitated, the fast and vigorous growth of grapes is promoted, the root and stem morphology is good, the germination of plants is promoted by applying high-efficiency compound fertilizer and urea, and the fast growth, high quality and high yield of grapes are realized.
Owner:横县生产力促进中心

Application of 7,3'-dimethoxy hesperetin in preparation of anti-inflammatory immune medicaments

The pharmaceutical application of a hesperetin derivative relates to the application thereof in the preparation of anti-inflammatory immune medicaments, in particular to the application in treatment of autoimmune diseases such as rheumatic, rheumatoid arthritis and osteoarthritis, and the like. The hesperetin derivative is the derivative which is prepared by a non-carbohydrate compound obtained by hydrolyzing hesperidin and removing glycosyl. The pharmacological effect of the hesperetin derivative is significantly higher than that of the parent hesperidin; and compared with traditional non-steroidal anti-inflammatory medicament naproxen and a medicament tripterygium treating rheumatoid arthritis, the hesperetin derivative has equivalent activeness, is safe and non-toxic, not only treats the symptom, but also treats the root, thus having very good medicinal prospect.
Owner:ANHUI MEDICAL UNIV

Balsampear stem stomach-invigorating beverage and processing method thereof

The invention relates to a processing method of a balsam pear vine stomach-strengthening drink. The balsam pear vine stomach-strengthening drink contains balsam pear vines, radish seedlings, ginger and plantain. The raw materials are made into a powdery / granular solid or liquid drink by a certain processing method, and the processing method concretely comprises the steps of grinding the raw materials, decocting the ground raw materials, decocting the ground raw materials repeatedly, filtering the obtained product and granulating the obtained product or preparing the obtained product into the drink. According to the compatibility principle of Chinese medicine, the processing method combines the medicines for mutual synergism. The balsam pear vine stomach-strengthening drink has the advantages of having efficacy in clearing heat and releasing toxin of intestines and stomach, eliminating dampness, promoting urination, relieving pain, stopping diarrhea, treating dysentery, resisting bacteria, diminishing inflammation, strengthening stomach, promoting digestion and the like, and capability of effectively regulating the functions of intestines and stomach with remarkable efficacy.
Owner:刘勇华

Application of 23-hydroxylbetulinic acid in preparing medicine for treating and preventing AIDS

The invention discloses a novel purpose of 23-hydroxylbetulinic acid, namely, an application of 23-hydroxylbetulinic acid in preparation of drug for treating or preventing AIDS. The drug for treating or preventing lever cancer is a drug compound with 23-hydroxylbetulinic acid as the active ingredient. 23-hydroxylbetulinic acid is safe, nontoxic, strong in pharmacological action and promising with a good prospect in pharmacy; pasqueflower, the Chinese traditional medicine, in the raw material, is rich in resource, low in cost and simple in preparation process.
Owner:叶文才

Azithromycin ophthalmic gel preparation composition and preparation and application thereof

InactiveCN101234079ATo achieve the absorption effectSolve the shortcomings of not easy to dissolveOrganic active ingredientsSenses disorderDiseaseAzithromycin
The invention discloses a novel composition of an ophthalmic Azithromycin gel preparation, a preparation method thereof and applications thereof. The researcher of the invention combines appropriate auxiliary materials with the combination of Azithromycin and citric acid to prepare the ophthalmic Azithromycin gel preparation; the combination of the Azithromycin and the citric acid in the invention can achieve better absorption of the Azithromycin, which resolves the problem that the Azithromycin is difficult to dissolve; meanwhile, the manufactured gel preparation can ensure that the drug have prolonged effects on lesion location to realize full absorption of the drug. The ophthalmic Azithromycin gel preparation of the invention has obvious pharmacological action and outstanding effects on treatment of such ophthalmic diseases as conjunctivitis, keratitis, trachoma, dacrocystitis, etc.
Owner:迈洋致达(北京)科技有限公司

Method for preparing valid target in gavel fruit vine fruit and application of the same

The invention relates to a preparation method of the effective parts of the fruit of the plant Capparis Spinosa, comprising the steps as follows: grinding the Capparis Spinosa fruit; extracting and decompressing with methanol or ethanol to get a crude extract; suspending the crude extract; degreasing with small molecular alkyl, then getting effective extract by extracting with butanol or eluting aqueous phase with water-alcohol system using macroporous resin column. The invention extracted from the effective part of Capparis Spinosa fruit is characterized in restraining proliferation of the fiber cell of the systemic sclerosis patients, expression of type I collagen and mRNA of the connective tissue growth factor, synthesis of protein, having no effect on proliferation of the fiber cell of the normal people, synthesis of collagen and expression of CTGF, being used in preparation of medicine for curing progressive systemic sclerosis, and facilitating a plurality of preparation comprising external use preparation and oral preparation. The preparation method has the advantages of reasonable design, simple technique process and low cost and energy consumption.
Owner:ZHEJIANG UNIV

New medicinal use of nintedanib, and derivative and medicinal salt thereof

The invention relates to new medicinal use of nintedanib, and a derivative and a medicinal salt thereof, in particular to the use in preparing a medicine for preventing and / or treating peritoneal adhesion. Animal experiment results show that the nintedanib can significantly reduce the occurrence of the peritoneal adhesion after abdominal surgery of rats, improve the texture of the peritoneal adhesion, reduce the toughness of the peritoneal adhesion, and reduce an inflammation and fibrosis degree of peritoneal tissues. An important theoretical basis for the use of the nintedanib, and the derivative or the medicinal salt thereof in treating peritoneal adhesion is provided, a treatment range of the medicine is widened, and meanwhile a new medicine solution for treating the peritoneal adhesion is provided.
Owner:CANCER INST & HOSPITAL CHINESE ACADEMY OF MEDICAL SCI

Pharmaceutical composition for treating cardiovascular and cerebrovascular diseases, preparation process and quality control method thereof

The invention provides a pharmaceutical composition for treating cardiovascular and cerebrovascular diseases, its preparing process and quality control method, wherein Dipyridamole and one or two of ligustilide and Ligusticum wallichii alkaloids are employed in combination to obtain various dose forms of injections and oral administration preparations. The composite preparation is mainly used for treating coronary disease, angina pectoris, cerebrovascular disease, pulmonary heart disease, and hypertension.
Owner:BEIJING QI YUAN YI DE PHARMA RESEARCH CENTER
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