109results about How to "Sensitive measurement" patented technology

Provided herein are methods of detecting an analyte of interest to interrogate spatial gene expression in a sample using RNA-templated ligation.

Provided herein are methods of detecting an analyte of interest to interrogate spatial gene expression in a sample using RNA-templated ligation.

The present invention provides fluorogenic probes and corresponding fluorescent compounds, methods of using the probes, compounds and kits that include the probes.

Embodiments of the invention relate to resonant circuits; particularly but not exclusively the embodiments relate to resonant circuits in RPID (radio frequency identification) responsive to a wide frequency range. A controllable electric resonator comprising an inductor coupled to a first capacitor to form a resonant circuit, the resonator further comprising a controllable element, a second capacitor controllable coupled across said first capacitor by said controllable element, and a control device to control said controllable element such that a total effective capacitance of said first and second capacitor varies over a duty cycle of an oscillatory signal on said resonator.

The invention provides an ATR spectrum measurement type Fourier transform spectrometer based on integrated optical waveguide. The spectrometer comprises an integrated optical waveguide electro-optical modulator, a voltage function generator, a broadband light source, a photoelectric detector, a signal processing chip and a fiber having an ATR sensitive window. According to the invention, light from the light source is coupled into the fiber, passes through an ATR sensitive window zone along the fiber and coupled into the integrated optical waveguide electro-optical modulator; voltage varying with time is applied on the integrated optical waveguide electro-optical modulator by using the voltage function generator, the intensity of output light of the integrated optical waveguide electro-optical modulator is measured by using the photoelectric detector simultaneously, and the signal processing chip connected with the photoelectric detector and the voltage function generator carries out Fourier transform processing on measured optical signals so as to obtain the spectrum of incident light. The spectrometer provided in the invention can determine visible-infrared absorption spectrum of solid, liquid and monomolecular layers adsorbed on the surface of the ATR sensitive window, has strong anti-interference capability and is applicable to on-site rapid quantitative detection.

The present invention provides fluorogenic probes and corresponding fluorescent compounds, methods of using the probes, compounds and kits that include the probes.

A method for designing a two-dimensional array overlay target set comprises the steps of: selecting a plurality of two-dimensional array overlay target sets having different overlay errors; calculating a deviation of a simulated diffraction spectra for each two-dimensional array overlay target set; selecting a sensitive overlay target set by taking the deviations of the simulated diffraction spectra into consideration; and designing a two-dimensional array overlay target set based on the structural parameters of the sensitive overlay target set.

Methods and devices for enhanced ultrasound detection based upon changing temperature and ultrasound reflectivity of a temperature-dependent contrast agent bound to an ultrasound target are disclosed. The methods and devices can be used for enhanced imaging alone or in conjunction with drug delivery, with therapeutic approaches such as hyperthermia or cryotherapy or with other imaging modalities.

Instrumentation for monitoring crack growth using a change in electric potential across a starter crack as the crack propagates is disclosed. The instrumentation includes a specimen of a material to be analyzed for crack growth propagation having a surface with a starter crack formed therein, a plurality of current leads to pass electric current through the specimen, a layer of insulating material disposed on each of opposite sides of the crack, a layer of conductive material disposed on each layer of insulating material, where a portion of each layer of conductive material is in electrical contact with the first specimen surface, and a pair of sensing leads, one sensing lead attached to each layer of conductive material. A method for using the instrumentation to monitor crack growth by measuring is also disclosed.