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103results about How to "Reduce the incidence of infection" patented technology

Surgical training and evaluation method on basis of virtual reality

The invention discloses a surgical training and evaluation method on the basis of virtual reality. The surgical training and evaluation method is implemented by a database module and execution modules. The database module is divided into a training and evaluation question bank, a surgical stage scene model library, a medical equipment and medicine model library and a disease and therapeutic schememodel library, the execution modules include a training and evaluation selection module, a surgical stage selection module, a medical equipment and medicine selection module and a disease and therapeutic scheme selection module, and the training and evaluation selection module is sequentially connected with the surgical stage selection module, the medical equipment and medicine selection module and the disease and therapeutic scheme selection module. The surgical training and evaluation method has the advantages that surgical training and evaluation can be accomplished by the aid of virtual reality systems, therapeutic schemes can be verified and simulated by the aid of the virtual reality systems, evolution mechanisms of diseases can be observed by the aid of the virtual reality systems,and environment-friendly and safe modes can be provided to surgical skill training and evaluation and therapeutic scheme design emulation; the technical problems of low efficiency, severe waste and high surgical risks of existing surgical training and evaluation methods can be solved by the aid of the surgical training and evaluation method.
Owner:CHINA THREE GORGES UNIV

Medical catheter carrying slow-release antibiotic coating and preparation method thereof

InactiveCN101628133ASolve technical problems that cannot withstand high temperaturesDoes not affect the effectCatheterCoatingsAcetic acidMedicine
The invention discloses a medical catheter carrying a slow-release antibiotic coating and a preparation method thereof. The outer surface of a catheter body (1) is coated with an antibiotic slow-release layer (2), and the antibiotic slow-release layer (2) is a high molecular polymer combined with an antibiotic, preferably a polylactic acid-polyglycollic acid coating. The preparation method comprises the following steps: preprocessing the medical catheter; preparing an acetone solution containing polylactic acid-polyglycollic acid; preparing coating liquid; and settling the coating. The invention has the function of obviously lowering the originating rate of the relevant infection of the catheter. The catheter releases the antibiotic from the inside to the outside in a certain time, directly kills bacteria at the periphery of the catheter and solves the technical problem that the antibiotic can not resist high temperature.
Owner:THE FIRST AFFILIATED HOSPITAL OF THIRD MILITARY MEDICAL UNIVERSITY OF PLA

Wound regenerating and repairing bandage and manufacture method thereof

The invention relates to the technical field of medical application, and in particular relates to wound regenerating and repairing bandage and a manufacture method thereof. The wound regenerating and repairing bandage comprises a surface protective layer, wherein a therapy pad is arranged at one side of the surface protective layer, and comprises a nano-fiber membrane, an anti-bacterial chitosan membrane and an alginate layer which are arranged in sequence; the alginate layer is connected with the surface protective layer. The wound regenerating and repairing bandage manufactured by using the method has a remarkable effect in stopping bleeding, resisting bacteria, accelerating wound heating and relieving pains for a wound, is excellent in adhesion, breathability and comfort, can prevent wound adhesion, and has high functions of water absorption and moistening.
Owner:深圳市博立生物材料有限公司

Novel poultry micro-ecological preparation and preparation method thereof

The invention relates to a novel poultry micro-ecological preparation and a preparation method of the novel poultry micro-ecological preparation. The preparation comprises following components in part by weight: 0.8-3.5 parts of vitamin A, 0.2-0.8 part of vitamin D, 2-8 parts of vitamin E, 0.2-1.2 parts of vitamin K, 0.1-0.9 part of vitamin B1, 0.2-0.8 part of vitamin B2, 0.1-0.7 part of vitamin B6, 0.08-0.5 part of vitamin B12, 2-5 parts of nicotinamide, 0.8-3.5 parts of calcium pantothenate, 0.02-0.4 part of folic acid, 0.2-1.2 parts of biotin, 0.02-2 parts of vitamin C, 1.3-32 parts of enterococcus faecium, 27-155 parts of bacillus subtilis, 75-210 parts of oligosaccharide, 150-400 parts of pine needle meal and 400-600 parts of bentonite. The novel poultry micro-ecological preparation can improve daily gain, feed intake, feed conversation efficiency of young poultry, reduces death and culling rate of the young poultry, and improves reproductive performance of breeding poultry, laying rate, fertilization rate of hatching eggs, hatching rate, and healthy rate of the young poultry. According to the invention, as double-layer shallow coating is performed to enterococcus faecium, the stress resistance of enterococcus faecium is improved.
Owner:北京福乐维生物科技有限公司

Multi-layer foam dressing for negative pressure closed drainage and preparation method thereof

The invention provides a multi-layer foam dressing for negative pressure closed drainage and a preparation method thereof. The multi-layer foam dressing for negative pressure closed drainage comprises a negative pressure conduction layer; the lower part of the negative pressure conduction layer is provided with a drainage protection layer which is contacted with a wound surface or a wound cavity; the negative pressure conduction layer and the drainage protection layer are porous foam material layers; the negative pressure conduction layer is a hydrophobic porous foam material layer; the drainage protection layer is a hydrophilic porous foam material layer; the two layers of materials are fixedly connected and pores mutually penetrate and are communicated. Two longitudinal broken joints are formed on the multi-layer porous foam dressing; the longitudinal broken joints are formed at the installation positions of negative pressure drainage tubes, and extend to the middle part of the multi-layer porous foam dressing from the installation ends of the negative pressure drainage tubes by passing through the installation positions of negative pressure drainage tube holes. The thickness a of the negative pressure conduction layer is 0.5cm to 10cm, the pore diameter is 1mm to 2.5mm, the thickness b of the drainage protection layer is 0.1cm to 3.5cm, and the pore diameter is 0.2mm to 1mm. Meanwhile, the invention also provides a splicing method and a compound method for preparing the foam dressing. According to the dressing and the method, a multi-layer structure is adopted, so that the negative pressure conduction performance can be effectively improved while the material safety is ensured; in addition, blockage does not easily occur during a use process, the permeability is stable, and the treatment effect is excellent.
Owner:WUHAN VSD MEDICAL SCI & TECH CO LTD

Disease preventing fish farming method

The invention belongs to the technical field of aquiculture, and particularly discloses a disease preventing fish farming method. The method mainly comprises the following respects: (1), fishpond management; (2), fingerling stocking; (3), feeding: feeding disease preventing fish feed according to body weight of fish; (4), water quality management: performing disinfecting for 2 to 3 times every month by using a disinfectant; the disease preventing fish feed is mainly prepared from bran, maize, a feed additive and inorganic salt in certain parts by weight; the feed additive is mainly prepared from basil, lonicera japonica, houttuynia cordata, folium perillae and rosmarinus officinalis in certain parts by weight; the disinfectant is mainly prepared from codonopsis pilosula, atractylodes macrocephala, bacillus licheniformis, nitrosobacteria and cyanobacteria in certain parts by weight. According to the method, the fish is fed via the improvement of aquiculture water quality and the adoption of disease preventing fish feed which is green, safe and good in disease prevention effect, the combination of the improvement of aquiculture water quality and the adoption of the disease preventing fish feed can effectively improve the disease prevention capacity of the fish, further the incidence rate of the fish is reduced, and the survival rate of the fish is improved.
Owner:陆川县恒伟养殖专业合作社

Novel catheter

The invention discloses a catheter, which comprises a catheter body. A urine inlet hole is formed on the head of the catheter body, and a urine drain hole is formed at the tail of the catheter body. The catheter is characterized by further comprising a head sleeve, wherein one end of the head sleeve is provided with notches or orifices, and the other end of the head sleeve is open and provided with a limiting flange; and the head sleeve can be movably sleeved outside the catheter body. The catheter provided by the invention can avoid bacteria on the inner side of a urethral orifice being brought into the deep part of the urethra and the bladder in a using process, and effectively reduces the occurrence of urinary tract infection of a patient.
Owner:SHANGHAI TENTH PEOPLES HOSPITAL

Antibacterial surgical suture without being taken out and preparation method thereof

The invention discloses an antibacterial surgical suture without being taken out and a preparation method thereof. The surgical suture is prepared from the following ingredients in parts by weight: 80to 100 parts of matrix resin, 1 to 10 parts of sodium carboxymethylcellulose, 1 to 10 parts of polyvinyl alcohol, 1 to 10 parts of glycerinum, 1 to 10 parts of calcium carbonate, 1 to 30 parts of starch, 1 to 10 parts of chitosan, 1 to 10 parts of silk fibroin, 1 to 10 parts of agar and 1 to 20 parts of aloe powder. The antibacterial surgical suture without being taken out disclosed by the invention has good biocompatibility, cells can normally grow on a base frame of the surgical suture, the surgical suture can be completely decomposed into water and carbon dioxide, secondary pain caused bytaking the suture out is avoided, and the surgical suture has antibacterial and anti-inflammation effects, can reduce an occurrence rate of postoperation wound infection and can promote wound healing.
Owner:SHANGHAI NAT ENG RES CENT FORNANOTECH

Percutaneous osseointegrated implant assembly for use in supporting an exo-prosthesis

An implant assembly (30) for a long bone is adapted to support an exo-prosthesis. The assembly (30) includes a stem (22), a subdermal component (24) and a percutaneous post (26). The stem (22) has a proximal end (34) that is adapted to be received in a surgically prepared medullary canal of the long bone, and a distal end (4) having a surface that is adapted to promote bone ingrowth. The subdermal component (24) includes a proximal portion (44) that is adapted for attachment to the distal end (40) of the stem (22), and a fixation surface (55) that is adapted to promote soft tissue fixation. The percutaneous post (26) has a proximal end that is adapted to be attached to the subdermal component (24).
Owner:UNIV OF UTAH RES FOUND +1

Hernia bioremediation mesh and preparation method thereof

The invention discloses a hernia bioremediation mesh and a preparation method thereof. The hernia bioremediation mesh is made of animal tissues, immune ingredients such as cells and DNA are removed, and the animal tissues are cut into thin strips, twisted into threads, and woven into the bioremediation mesh. Xenogeneic decellularized materials obtain greater intensity through twisting into the threads, so that the xenogeneic decellularized materials are not prone to breaking; since the threads are interwoven with each other after weaving, external force of tensile tearing does not act on one point but on a plurality of interwoven points, so that the mechanical properties are good; and the defects that the xenogeneic decellularized material hernia bioremediation mesh has poor mechanical intensity and needs to be introduced with cross-linking agents or synthetic materials are overcome. The structure of the mesh is prepared by a weaving process, and the size of a mesh aperture can be easily adjusted through weaving parameters, so that requirements of practical application are met. Meanwhile, the hernia bioremediation mesh retains an original three-dimensional structure, non-collagen proteins, growth factors and other components of an extracellular matrix, so that the functional reconstruction and postoperative healing of the tissues are promoted.
Owner:上海白衣缘生物工程有限公司

Trachea cannula capable of removing sputum accumulation and relieving inflammatory reaction

The invention relates to a trachea cannula capable of removing sputum accumulation and relieving inflammatory reaction. The trachea cannula is provided with a cannula body, a breathing machine connector, an air vent, an airbag, an inflating passage and an inflating tube, wherein hydrophobic and oleophobic layers are arranged on the inner wall and the outer wall of the cannula body as well as on the outer wall of the airbag; a plurality of convex rings are arranged on the airbag, and the convex ring at the nearest end protrudes towards a near end, so that an accommodating groove is formed between a balloon and the cannula body; the edge of the air vent is coiled towards the near end, so that a receiving groove is formed; a sputum suction passage is formed in the inner wall of the cannula body; the sputum suction passage is provided with a first sputum suction hole and a second sputum suction hole; an opening at the far end of the sputum suction passage is a third sputum suction hole; the first sputum suction hole is opened outwards; the second sputum suction hole communicates with the accommodating groove; the third sputum suction hole communicates with the receiving groove; and a sputum suction tube is connected to the near end of the sputum suction passage. With the application of the trachea cannula provided by the invention, sputum can be thoroughly removed, planting and growth of pathogenic bacteria can be relieved, and an infection probability and an occurrence rate of the inflammatory reaction can be reduced; and the trachea cannula is fixed more firmly and cannot cause displacement and air leakage easily.
Owner:SHANGHAI FIRST PEOPLES HOSPITAL

Interchangeable unicondylar femoral prosthesis system and knee joint system

The invention relates to an interchangeable unicondylar femoral prosthesis system and a knee joint system. The interchangeable unicondylar femoral prosthesis system comprises at least two types of femoral prostheses, wherein each type of femoral prosthesis comprises an osteotomy surface used for being connected with a femur and an articular surface used for being matched with a tibia liner; a fixing part is arranged on each osteotomy surface; each articular surface comprises a posterior condylar articular surface, wherein the maximum distance between the fixing piece and the posterior condylearticular surface is recorded as a first distance, and the first distances of different types of femoral prostheses are the same. The interchangeable unicondylar femoral prosthesis system retains morebone mass of a patient, simplifies operation steps, shortens operation time and reduces infection probability.
Owner:SUZHOU MICROPORT ORTHORECON CO LTD

Composition and eczema paste containing same

The invention belongs to the field of nursing compositions, and discloses a composition, which comprises following components in parts by weight: 0.005 to 0.5 part of sunflower oil unsaponifiable matter, 0.001 to 0.1 part of balloon vine flower / leaf / vine extract, 0.01 to 1 part of echium plantagineum seed oil, 0.001 to 5 parts of tocopherol, 0.1 to 0.3 part of chlorhexidine and chlorhexidine derivatives, 0.1 to 10 parts of paeonol, and 1 to 20 parts of camellia seed oil. The invention aims to provide a composition, which has a good effect on treating eczema, in particular, eczema of babies, the composition has the advantages of mild property, effectiveness, high cure rate, and rapid effect, and the invention also provides an eczema paste containing the composition.
Owner:广州蜜颜秀生物科技有限公司

PRP loaded slow release antibiotic-mesenchymal stem cell gel system and preparation method thereof

InactiveCN106362213ASolving the technical challenges of healingTechnical Difficulties in Promoting HealingTissue regenerationProsthesisMuscle tissueAntibiotic Y
The invention discloses a PRP loaded slow release antibiotic-mesenchymal stem cell gel system and a preparation method thereof. Thrombin and calcium ions are added into PRP, an irregular micro three-dimensional grid structure of 50-200 micrometers is formed, and bacterium-sensitive antibiotics and stem cells are loaded on the grid structure. The PRP loaded slow release antibiotic-mesenchymal stem cell gel system and the preparation method thereof have the advantages that open fractures, bone and joint infection, skin, subcutaneous tissue and muscular tissue infection, four limb and spine implant related infection and artificial joint prosthesis peripheral infection are obviously prevented and treated, and the related infection occurrence rate is reduced. The technology releases the antibiotics within a certain time from inside to outside, bacteria around an implant are directly killed, formation of a bacterial biofilm is restrained or damaged, and the technical purpose that coalescence of bone joints and soft tissue is promoted while the antibiotics are slowly released in the body is achieved.
Owner:THE THIRD AFFILIATED HOSPITAL OF THIRD MILITARY MEDICAL UNIV OF PLA

Multi-layer foam dressing for negative pressure sealing drainage and manufacturing method thereof

The invention provides a multi-layer foam dressing for negative pressure sealing drainage and its manufacturing method. The multi-layer foam dressing for negative pressure sealing drainage includes a negative pressure conduction layer, which is arranged at the lower part of the negative pressure conduction layer for contact with the wound surface or The drainage protection layer in contact with the wound cavity, the negative pressure conduction layer and the drainage protection layer are both porous foam material layers; the negative pressure conduction layer is a hydrophobic porous foam material layer, and the drainage protection layer is a hydrophilic porous foam Material layer, two layers of materials are fixedly connected and the pores are infiltrated and communicated with each other. There are two longitudinal fractures on the multi-layer foam dressing, the longitudinal fractures are located at the position where the negative pressure drainage tube is installed, and one end of the negative pressure drainage tube is installed through the position where the hole of the negative pressure drainage tube is installed to extend to the multi-layer The middle of the foam dressing. The thickness a of the negative pressure conducting layer is 0.5-10 cm, and the pore diameter is 1-2.5 mm. The thickness b of the drainage protection layer is 0.1-3.5 cm, and the pore diameter is 0.2-1 mm. Simultaneously, the invention also provides two methods of making the above-mentioned foam dressing, bonding and compounding. The invention adopts a multi-layer structure, which can effectively improve its negative pressure conduction performance while ensuring the safety of the material, and is not easy to be blocked during use, has stable permeability and excellent therapeutic effect.
Owner:WUHAN VSD MEDICAL SCI & TECH CO LTD

Composite membrane for guided bone regeneration and preparation method of composite membrane

The invention discloses a composite membrane for guided bone regeneration and a preparation method of the composite membrane. The preparation method of the composite membrane includes the operation steps: treating pig jejuna by a mechanical method to obtain small intestinal submucosa; performing multilayer horizontal-vertical overlapping after processes such as acid, decontaminant and alkali treatment to obtain a compact layer; uniformly spinning prepared collagen solution on the compact layer by an electrospinning technique, and performing compounding and vacuum freeze-drying to obtain the composite membrane. The composite membrane prepared by the method has excellent biocompatibility and bioactivity and is easily absorbed by tissues, the compact layer in a structure can selectively stopsoft tissues from growing into a bone defect area, a loose layer is of a loose porous structure and large in specific surface area by the aid of the electrospinning technique, combination of two membranes, cell adhesion and growing into pores are facilitated, new tissue regeneration can be supported by the aid of bioactive factors or medicines, and wound healing is promoted. By combination, the composite membrane achieves excellent mechanical performance and can keep a regeneration space stable within a certain time.
Owner:上海白衣缘生物工程有限公司

Visual puncture outfit

The invention relates to a visual puncture outfit. The visual puncture outfit comprises a sheath tube assembly, a puncture rod and a camera assembly, wherein the sheath tube assembly comprises an outer sheath tube which is through from top to bottom; the puncture rod is arranged in a passage of the outer sheath tube; the camera assembly is arranged in the passage of the outer sheath tube and can rotate by a certain angle in the passage of the outer sheath tube. The visual puncture outfit can be used for establishing an operation channel, and the camera assembly of the visual puncture outfit not only can rotate by a certain angle in the horizontal direction but also can move along the longitudinal direction, so that the visual puncture outfit can be used to observe an operation scene at anytime and adjust a shooting angle at any time according to actual requirements, and thus operation can be carried out better.
Owner:上海大博医疗科技有限公司

Pea protein low-residue nutritional formula product and preparation method and application thereof

The invention provides a low-residue nutritional formula product and a preparation method and application thereof. The product does not contain dietary fibers and is applicable to patients who need toget intestinal tract cleaning preparation for performing intestinal tract inspection and intestinal tract operations. The product contains protein, carbohydrates, fat, minerals and vitamins, and theprotein selects pea protein with lower anti-nutritional factors. Compared with a conventional intestinal tract cleaning mode, the intestinal tracts treated by the product provided by the invention have high cleanliness, high detection rate of adenomas and polyp of the intestinal tracts, low gas production rate, good nutrient support and high patient suitability.
Owner:北京麦孚医学科技有限公司 +2

Medical biological yarn, medical biological repair mesh and preparation method thereof

The invention discloses a medical biological yarn, a medical biological repair mesh and a preparation method thereof. The medical biological yarn can be woven into the repair mesh by taking tissues ofan animal as a raw material, removing immune components such as cells and DNA and slicing the raw material into strips and twisting the strips to the yarn. A special cell-removal material is twistedto yarns to obtain greater strength, so that the yarns are hard to break. The yarns are interwoven after being woven, a stretching and tearing external force is not applied to one point but to multiple interwoven points, so that the yarn has good mechanical property. The defect that the mechanical strength of the biological repair mesh is poor and a crosslinking agent or a synthetic material is needed is overcome. Moreover, the structure of the mesh is prepared from a weaving process. The size of the pore diameter of the mesh can be adjusted easily by means of weaving parameters to meet the demand of actual applications. In addition, the medical biological yarn keeps original components such as three-dimensional structures, collagenous fibers, non-collagenous fibers and growth factors in an extracellular matrix and promotes functional reconstruction and postoperation reunion of tissues.
Owner:上海白衣缘生物工程有限公司

Flushing drainage tube

InactiveCN103083787AAvoid blockingLarge flush rangeCatheterStomaSurgical site infection
The invention discloses a flushing drainage tube which comprises a drainage tube and a flushing tube, the middle section of the flushing tube runs inside the drainage tube, parts of the flushing tube are arranged inside the drainage tube, two ends of the flushing tube stretch out of the drainage tube, drainage holes which are distributed in staggering and unsymmetrical arrangement at intervals are formed in the lateral sides and upper side of the front end tube wall of the drainage tube, the front end of the drainage tube is in a fish mouth shape, the tail end of the drainage tube is provided with a connector which is connected with a negative pressure device, 2-3 protrudent ridges are formed in the bottom of the inside of the drainage tube, and the tail end of the flushing tube is connected with flushing fluid. According to the flushing drainage tube, the range of flushing and drainage is large, block is not prone to happening, and the indwelling time inside a body is long. Medicine flushing drainage, pure drainage and pure medicine injection can be conducted according to the needs, so that exudative blood in surgical sites can be effectively drained, the union of nidus and anastomotic stoma is accelerated, anastomotic leakage can be observed, prevented and treated, surgical site infection is avoided, and clinical application is wide in range.
Owner:昆明理工大学附属医院

Trepan broken-nail extractor

InactiveCN101940497AReduce the incidence of infectionImprove the efficiency of broken nail removalOsteosynthesis devicesPostoperative wound infectionsDrill
The invention relates to medical appliances of orthopedic operations, and discloses a trepan broken-nail extractor. In the invention, an inverted-tooth trepan is arranged at the front port of a holding handle of the trepan broken-nail extractor, and the rear end of the holding handle is matched with the drill opening of an electric drill. Because the rear end of the holding handle can be matched with the drill opening of the electric drill, electromotive power can be used for replacing manpower to extract a broken nail when the broken nail is extracted. The invention greatly improves the efficiency of broken-nail extraction, saves the time and the labor and shortens the operation time, thereby reducing the time of intraoperative hemorrhage and wound exposure and reducing the incidence rate of postoperative wound infection.
Owner:洪潮 +1

Marine fish oligopeptide low-residue nutritional formula product and preparation method and application thereof

The invention provides a low-residue nutritional formula product and a preparation method and application thereof. The product is not added with dietary fibers and is suitable for patients needing toundergo intestinal cleaning preparation for intestinal examination and intestinal surgery. The product contains protein, carbohydrate, fat, minerals and vitamins, marine fish oligopeptide with smallermolecular weight is adopted to replace collagen, nutrient ingredients which can be more easily absorbed are provided while ultralow residue is kept, and thereby, while the intestines are cleaned andthe production of intestinal gas is reduced, sufficient nutrition is provided for patients. Compared with the conventional intestinal cleaning method, the preparation method provided by the inventionhas the following advantages that the cleanliness of the intestines treated by the produced disclosed by the invention is high, the intestinal adenoma and polypus detection rate is high, the amount ofproduced gas is small, nutritional support is good, and the applicability to patients is high.
Owner:麦孚营养科技(北京)有限公司 +1

Artificial skin graft for genipin immobilized activin B and preparation method thereof

The invention discloses an artificial skin graft for genipin immobilized activin B and a preparation method thereof. The artificial skin graft comprises hydrogel prepared from a skin graft stent material, and activin B which is distributed in the hydrogel and is cross-linked through genipin. The preparation method comprises the following steps of: sequentially adding an aqueous solution of genipin and the activin B into an aqueous solution of the skin graft stent material, uniformly mixing, forming, processing, gelatinizing and obtaining the product. The product is non-toxic, does not have pyrogenicity and has a high biocompatibility; pathogenic microorganism intrusion can be prevented, and infection incidence is reduced; quick healing of epithelial tissues can be promoted; and moreover, the exudation of wound surface fluid is reduced, a locally wet microenvironment is kept, the conventional disinfection and sterilization can be performed, and the artificial skin graft is convenient to storage and transport and is applied to burn, trauma and other skin injury repair.
Owner:广州优特佳生物科技发展有限公司

Bacillus velezensis as well as compound bacteria preparation and application thereof

The invention relates to bacillus velezensis MVCR2 which can improve the immunity of rainbow trout and has a remarkable inhibition effect on aeromonas salmonicida and vibrio anguillarum. The invention further relates to a compound bacterium preparation containing the bacillus velezensis MVCR2. The invention further relates to application of the bacillus velezensis MVCR2. The bacillus velezensis MVCR2 disclosed by the invention is preserved in the China Center for Type Culture Collection, the strain preservation number is CCTCC NO: M 2021507, and the preservation date is May 8, 2021, and the preservation number is CCTCC NO: M 2021507. The bacillus velezensis MVCR2 has a remarkable inhibition effect on aeromonas salmonicida and vibrio anguillarum, has an effective prevention and treatment effect on various aquaculture diseases caused by the aeromonas salmonicida and the vibrio anguillarum, and can improve the growth and immunity of rainbow trout, increase the survival rate of rainbow trout and reduce the death rate of freshwater rainbow trout in the sea.
Owner:QINGDAO AGRI UNIV

Uses of thymopeptide alpha1 in pulmonary fibrosis drug preparation

The present invention belongs to the technical field of medicine, and relates to new medicinal uses of thymopeptide alpha1, specifically to uses of thymopeptide alpha1 in pulmonary fibrosis drug preparation. Based on disadvantages of extremely poor prognosis, no effective treatment method, extremely high death rate and the like in idiopathic pulmonary fibrosis treatment by using the existing drugs, a strategy for targeted Th1 type reaction increase or Th2 type reaction inhibition is adopted, thymopeptide alpha1 is adopted as an immune modulator to increase the Th1 type immune reaction and other immune modulation effects, and animal experiment results show that immune disbalance of the pulmonary fibrosis body can be corrected with the thymopeptide alpha1, infection incidence rate can be significantly reduced, and death rate can be reduced, such that the thymopeptide alpha1 can further be used for preparation of pulmonary fibrosis drugs. According to the present invention, under the status of lack of effective pulmonary fibrosis disease treatment drugs, important clinical values are provided, and reliable experimental basis is provided for wide clinical applications.
Owner:SHANGHAI PULMONARY HOSPITAL
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