62results about How to "Reduce fatty degeneration" patented technology

The invention discloses a traditional Chinese medicine health product preparation for preventing and treating alcohol liver disease and a preparation method. According to the parts by weight, the traditional Chinese medicine health product preparation is prepared by adopting the following raw materials: 250 to 328 parts of pueraria flower, 250 to 328 parts of semen hoveniae, 250 to 328 parts ofradix puerariae, 125 to 164 parts of fructus amomi, 250 to 328 parts of dark plum fruit, 250 to 328 parts of date and 125 to 164 parts of liquoric root. The traditional Chinese medicine health product preparation can effectively prevent the alcohol from causing GSH exhaustion and MDA rising of the liver, reduce fatty degeneration of liver cells and has the function of preventing alcoholic liver damage; the health product preparation has condense medicinal odour, stable and controllable preparation technique and product quality, obvious curative effect and fast effect; the provided formulation has convenient in use, reduces the oral dosage; and in the formulation, all the drug contents are obtained from natural resources, has lower cost and is conveniently to promote and broad masses of the people are willing to adopt the traditional Chinese medicine health product preparation.

The invention discloses medicinal steamed bread for treating diabetes. Every 100 grams of steamed bread contain 3-10 percent by weight of medicament which is prepared from the following raw materials in parts by weight: 10-6 parts of Chinese yam, 10-5 parts of gorgon euryale seed, 10-3 parts of fragrant solomonseal rhizome, 8-3 parts of common anemarrhena, 8-3 parts of Mongolian snakegourd root, 8-3 parts of sophora flower, 8-2 parts of sealwort, 8-2 parts of corn stigma, 6-2 parts of dwarf lilyturf root, 6-2 parts of asparagus, 6-2 parts of propolis, 6-1 parts of curcumin and 6-1 parts of mulberry leaf. The medicinal steamed bread can be used for relieving, improving, preventing and treating diabetes type I and diabetes type II, so that the aims of relieving, improving, preventing and treating with medicinal foods are achieved.

The invention discloses an application of lactobacillus rhamnosus CCFM1060 in preparation of functional microbial agents, foods and / or medicines. The lactobacillus rhamnosus CCFM1060 can tolerate thegastrointestinal environment of the human body, significantly improve fasting blood glucose rise and abnormal oral glucose tolerance of type 2 diabetics caused by high fat diet and STZ injection, reduce the area under the curve during glucose tolerance drug administration, and relieve insulin resistance; remarkably improve the increase of total cholesterol content and the increase of low-density lipoprotein cholesterol in serum of type 2 diabetics caused by high-fat diet and STZ injection; obviously relieve the inflammatory state of the liver; and significantly reduce pancreatic and liver pathological injuries caused by high-fat diet and STZ injection. The lactobacillus rhamnosus CCFM1060 has relatively strong adsorption capacity on perfluorooctanoic acid (PFOA), and has the capacity of relieving the toxicity of the PFOA.

The invention relates to the field of microorganisms, and discloses lactobacillus fermentum with a weight reducing function and an application of the lactobacillus fermentum. The lactobacillus fermentum is named as WHH3906, is separated from butter collected in Tibet Autonomous Region in China, is preserved in China General Microbiological Culture Collection Center on March 13, 2020, has a preservation number of CGMCC NO.19472, and is classified and named as lactobacillus fermentum. The lactobacillus fermentum strain can effectively reduce serum leptin level to recover leptin sensitivity of anorganism, effectively prevent and treat obesity, relieve non-alcoholic fatty liver and relieve chronic inflammation. After being compounded with lactobacillus plantarum 1701, the lactobacillus fermentum can synergistically relieve chronic inflammation.

The invention discloses lactobacillus plantarum and application thereof in preparation of medicine or food for relieving diseases caused by hyperlipidemia, and belongs to the technical field of microorganism application. The lactobacillus plantarum is lactobacillus plantarum HH19058, and is preserved in the China Center for Type Culture Collection on December 24, 2020, the preservation number is CCTCC NO: M 2020966, and the address is located in Wuhan University, #299, Bayi Road, Wuchang District, Wuhan City, Hubei Province. The lactobacillus plantarum HH19058 is separated from pickled vegetables, has the effects of reducing the blood fat content of the human body and reducing the cardiovascular disease morbidity, and can be used for preparing the food and the medicine for relieving the hyperlipidemia.

The invention provides a dendrobium kudzu eucommia bark functional food, and relates to a health food which can offer auxiliary protection for chemical liver injury and improve immunity, in particular to a health care functional food which takes dendrobium as a monarch drug. The food is prepared by uniformly mixing dendrobium powder with granularity no less than 60 meshes, kudzu extractive with eucommia bark extractive, and the dendrobium powder, the kudzu extractive and the eucommia bark extractive are mixed by the following weight fraction: 6-10 parts of dendrobium, 1-3 parts of kudzu extractive, and 1-2 parts of eucommia bark extractive. The functional food is characterized in that a liver-protective drug which is homology of medicine and food, a drug of nourishing yin and varieties which have the function of tonifying yang are organically combined by a reasonable method to produce a health food with remarkable effects. The functional food has the efficacy of protecting liver, improving eyesight, moistening lung, nourishing stomach, and adjusting the equilibrium between yin and yang in human body, and can achieve the effect of notably improving chemical liver injury and a series of symptoms caused by low immunity.

The invention provides a Chinese compound medicinal preparation for treating hypertension and hyperlipemia, and its preparing process, wherein the preparation comprises (by weight ratio) eucommia leaves 5000-10000 parts, bitter leaves tea 1000-5000 parts and right amount of auxiliary materials.

The invention provides a liver-protecting medicine or a health-care product composition, which is a chewable tablet prepared from the following materials in parts by weight: 100-200 parts of folium cortex eucommiae extract, 115-345 parts of honeysuckle extract, 25-100 parts of reishi shell-broken spore powder, 35-280 parts of chrysanthemum extract, 25-100 parts of beta-cyclodextrin, 130-705 parts of filler, 11-39 parts of a disintegrating agent, 1.8-6.5 parts of a binder, 0.9-3.5 parts of a flavoring agent, and 0.8-14.5 parts of a lubricating agent. The medicine or the health-care product composition disclosed by the invention plays a role of synergistic interaction after four materials of folium cortex eucommiae are used in compatibility, can effectively reduce an injury of alcohol on the liver, and reduces steatotic hepatocyte; the composition is safe and nontoxic; and a new choice is provided for the liver-protecting medicine or the health-care product. The chewable tablet prepared by the preparation method is good in mouthfeel and appearance, and has a good commercial application prospect; the compliance is improved; and the range of users is also expanded.

The invention relates to a method for improving the anticancer activity for Codonopsis lanceolata Benth.et Hook.F, which comprises: slicing or homogenizing fresh Codonopsis lanceolata Benth.et Hook.F, or crushing dry Codonopsis lanceolata Benth.et Hook.F, or powdering the dry Codonopsis Lanceolata Benth.et Hook.F; soaking in water; sterilizing under a high pressure; adding 0.5 to 5.0 percent of active yeast and 1 to 8 percent of glucose under a sterile condition when the temperature lowers to 30 DEG C; fermenting at 20 to 37 DEG C for 1 to 10 days, and adding a polar solvent after fermentation to extract for 5 to 24 hours at 0 to 100 DEG C; and filtering, recovering solvent and concentrating under reduced pressure or drying by freezing. The method can improve the inhibition effect of Codonopsis lanceolata Benth.et Hook.F on the growth of tumors.

The invention relates to a feed additive for ducks, which consists of, by proportion, traditional Chinese medicine ingredients including hawthorn 10-20 parts, honeysuckle 10-20 parts, cinnamon 5-15 parts, rheum officinale 5-15 parts, oriental wormwood 5-15 parts and jasmine 5-15 parts, enzymic preparations including cellulose 4-10 parts, neutral protease 4-10 parts and phytase 4-10 part and microecologics including bifidobacterium 1-3 parts, lactobacillus plantarum 1-3 parts and lactobacillus casei 1-3 parts. The feed additive for ducks has the advantages of whetting appetite, promoting animal growth and feed digestion, improving body immune functions, preventing and curing duck viral hepatitis, improving commodity value, and being free of toxic and side effects and drug residues, and is a green and safe feed additive.

The invention discloses a fruit lucid ganoderma health care beverage, which is characterized in that the invention contains 800 to 1200 parts of fruit beverage and 5 to 20 parts of lucid ganoderma according to parts by weight, the fruit beverage is one of fruit wine and fruit juice, the lucid ganoderma powder is smashed and soaked, the juice is taken by a filter press and is blended with the fruit beverage, the impurities and suspension matters are filtered to prepare the invention; the invention has unique flavor, good taste and rich nutrition, the long-term drinking of the invention can improve the functions of coronary artery, improve the central nervous diseases and have certain prevention and treatment effects on coronary heart disease, chronic hepatitis and insomnia; the preparation method of the invention has simple process and low production cost, and the invention can bring the health care functions of the contained ingredients into full play.

The invention provides a compound liver-protecting traditional Chinese medicine for treating non-alcoholic fatty liver disease (NAFLD), which comprises the following components in parts by weight: 2-10 parts of chitosan oligosaccharide, 3-20 parts of salidroside, 5-10 parts of resveratrol, 10-20 parts of astaxanthin and 5-15 parts of stichopus japomicus slelenka glycosaminoglycans. According to the invention, through NAFLD mouse model experiments in vivo and vitro, five bioactive ingredients of the salidroside, chitosan oligosaccharide, resveratrol, astaxanthin and stichopus japomicus slelenka glycosaminoglycans are determined by a cell and molecular biology method, and after the bioactive ingredients are scientifically proportioned, lipid metabolism related genes can be adjusted, the effect of reducing the content of triglyceride in NAFLD liver cells is obvious, cell apoptosis induced by fatty acid can be relieved, hepatic steatosis of high-fat diet mice can be relieved, the TG content in the liver can be reduced, the medicine does not have obvious side effects and has no cytotoxicity, and the immune balance of the organism can not be damaged.

The invention discloses an application of ginsenoside CK and Rh1 and a composition thereof in preparation of medicine for improving non-alcoholic fatty hepatic fibrosis and insulin resistance, and relates to a medical application of the ginsenoside CK and Rh1 and the composition thereof. According to the application, in-vitro and in-vivo studies show that the ginsenoside CK and Rh1 and the composition thereof can regulate and control synthesis and degradation of epimatrix of hepatic stellate cells (HSC-T6) of mice, significantly improve the abnormal liver function, lipid metabolism disorders, abnormal glucose metabolism and hepatic fibrosis degree of the non-alcoholic fatty hepatic fibrosis mice, and has a development prospect for serving as the medicine of combination of non-alcoholic fatty hepatic fibrosis and insulin resistance.

The invention provides a compound feed for caged laying ducks. The feed consists of the following raw materials: corn, rice bran, soybean meal, meat and bone meal, distiller's dried grains with solubles, saccharomyces cerevisiae-fermented distiller's grains, barley, middling flour, calcium hydrogen phosphate, lysine, methionine, threonine, choline chloride, salt, phytase, a complex enzyme preparation, montmorillonite, vitamin C, multivitamins and complex trace elements. The invention adopts the combination of the saccharomyces cerevisiae-fermented distiller's grains, the meat and bone meal, the montmorillonite and the vitamin C, and takes into consideration the production and health of laying ducks, so that the laying ducks have the characteristics of comprehensive nutrients, high laying rate, stable egg production and long peak laying days. The feed can significantly improve the anti-stress ability and immunity of laying ducks, and effectively solve the problems of poor eggshell quality and high mortality and elimination rate of caged laying ducks. The invention also discloses a preparation method of the compound feed for caged laying ducks, and the method has the characteristicsof being simple in process, convenient for process parameter control and suitable for large-scale production.

The invention relates to a preparation method of a duck nano-feed additive. The raw materials of the duck nano-feed additive comprise traditional Chinese medicinal components, enzymatic preparations and microecological preparations. The duck feed additive provided by the invention has the characteristics of increasing appetite, promoting growth of animals and digestion of the feed, enhancing organism immunity, preventing and curing duck virus hepatitis, increasing commodity value and having no toxic and side effects and chemical residues, thereby being a green and safe feed additive.

The invention relates to a medicinal composition for treating fatty liver comprising giant knotweed, curcuma, silymarin, silymarin and common evening primrose oil and a method for preparing same. The medicinal composition is prepared into tablet, soft capsule, capsule, drop pill and granule. It has protection function on acute liver injury and can prevent and treat fatty liver, lower blood fat, relieve blood stasis and resist overoxidation injury.

The invention relates to a pharmaceutical composition for treating fatty liver and a preparation method thereof. The active ingredients contained in the traditional Chinese medicine composition are made from Polygonum cuspidatum, turmeric, silymarin and evening primrose oil. The pharmaceutical compositions of the present invention are tablets, soft capsules, capsules, dropping pills and granules. The traditional Chinese medicine composition of the invention has protective effect on acute liver injury, prevention and treatment effect on fatty liver, strong anti-peroxidative damage ability, blood lipid-lowering effect and blood rheology improvement effect on blood stasis syndrome, and can be used for treatment fatty liver.

The present invention discloses a dendrobium huoshanense, curcumin and kudzuvine root capsule and a preparation method thereof. The dendrobium huoshanense, curcumin and kudzuvine root capsule is composed of the following components in parts by weight: 1-3 parts of a dendrobium huoshanense extract, 3-7 parts of a kudzuvine root extract, 1.5-4 parts of curcumin, 1-3 parts of accessory materials and0.02-0.1 part of a lubricant. The dendrobium huoshanense, curcumin and kudzuvine root capsule cooperates all parties, is sweet, moist and mild, nourishes yin and benefits yang, searches yang from yinto enabling yang to be assisted by yin to achieve infinite energy, searches yin from yang to enabling yin to be assisted by yang to be endless in source, also calms liver and releases heat, sends up lucid yang, regulates state of human body functions together, thus strengthens body resistance and eliminates evil, mobilizes defense functions of human body, achieves a purpose of protecting liver together, and has very good health-care efficacy for people with low immunity. The present invention also provides the preparation method of the dendrobium huoshanense, curcumin and kudzuvine root capsule. In the capsule prepared from the above prescription and auxiliary materials, the active ingredient crude polysaccharide (based on anhydrous glucose) is larger than or equal to 1,100mg / 100g; puerarin is larger than or equal to 460mg / 100g; and the curcumin is larger than or equal to 10,000mg / 100g.

The invention discloses construction and application of an inflammation molecule (PSGL-1) missing abnormal lipid metabolism model. A construction method of the model comprises: based on an abnormal lipid metabolism model-LDLR (Low Density Lipoprotein Receptor) knockout mouse, i.e., an LDLR<- / -> mouse, carrying out modification on a PSGL-1 gene in a genome of the LDLR<- / -> mouse to enable expression of a PSGL-1 protein to be blocked so as to obtain a PSGL-1 missing and lipid metabolism disorder combined transgenic animal model-an LDLR<- / ->, PSGL-1<- / -> mouse. Research finds that after the mouse is induced for 12 weeks by high fat diet, relative to the LDLR<- / -> mouse, the newly constructed LDLR<- / ->, PSGL-1<- / -> mouse has the advantages that contents of total cholesterol and low density lipoprotein in the serum are reduced, and content of high density lipoprotein is increased; the LDLR<- / ->, PSGL-1<- / -> mouse has the advantages that hepatic lobule fatty degeneration is obviously reduced, and the areas of atherosclerotic plaques of aortas and aorta roots are obviously reduced. The model provides a new research carrier for systematically researching a mutual relationship of inflammation molecule and lipid metabolism and searching new drug target and treatment methods.

The present invention belongs to the field of health-care products and particularly relates to an alcoholism-preventing and liver-protecting agent containing chicory nutrient components and a preparation method thereof. The alcoholism-preventing and liver-protecting agent is prepared from chicory oligopeptide, chicory coumarin, a traditional Chinese medicinal extract, honey and deionized water according to a certain ratio; the chicory oligopeptide and chicory coumarin are extracted from chicory roots; the chicory oligopeptide is rich in amino acids of alanine, leucine, etc., can promote production of coenzyme NAD+ of ethanol dehydrogenase, is beneficial to catabolism of ethanol in body, inhibits rise of the ethanol in blood, and achieves an alcoholism-preventing purpose; the chicory coumarin can accelerate cell repair and has obvious protective effects on liver cells; and the traditional Chinese medicinal extract is prepared by extracting pueraria lobata flowers, pueraria lobata roots,pseudo-ginseng, silybum marianum, chrysanthemum, raisin tree seeds and nutmegs. By combing the active ingredients, the alcoholism-preventing and liver-protecting agent inhibits gastrointestinal absorption of alcohol, accelerates metabolism of the ethanol, reduces damage of the ethanol to the liver cells, and can play significant roles in preventing alcoholism and protecting the liver.

The invention discloses application of methyl palmitate in preparing a drug for preventing or treating fatty liver. Compared with the prior art, the invention finds that the methyl palmitate can be used for preventing or treating the fatty liver and particularly for non-alcohol fatty liver for the first time, and the treatment effect is significant. The research proves that the methyl palmitate can alleviate the liver fatty degeneration, inflammation and fibrosis, can alleviate the abnormal accumulation of liver lipid and can reduce the oxidation stress.

The invention relates to a Chinese medicinal composition for treating hepatic diseases, which is prepared from effective compositions extracted from red sage root and curcuma longa, wherein wherein the weight ratio of the red sage root effective composition and curcuma longa effective composition is 1:0.5-1:2. The medicinal composition can effectively treating fatty liver, liver fibrosis and hepatocyte necrosis.

The invention discloses application of a fructan extract in preparing medicines, foods or health products for treating fatty liver. The molecular weight of the fructan extract is 2500-8000. The fructan extract is prepared by the following steps: extracting Sichuan ophiopogon root tuber with ethanol to remove impurities, extracting with water, carrying out ethanol fractional precipitation, and drying to obtain the fructan extract (the molecular weight is 2500-8000). The inspection on functions of the fructan extract by a diet-induced fat mouse model proves that the fructan extract has an obvious action of treating fatty liver.

The invention discloses an application of ginsenoside CK and Rh1 and a composition thereof in preparation of medicine for improving non-alcoholic fatty hepatic fibrosis and insulin resistance, and relates to a medical application of the ginsenoside CK and Rh1 and the composition thereof. According to the application, in-vitro and in-vivo studies show that the ginsenoside CK and Rh1 and the composition thereof can regulate and control synthesis and degradation of epimatrix of hepatic stellate cells (HSC-T6) of mice, significantly improve the abnormal liver function, lipid metabolism disorders, abnormal glucose metabolism and hepatic fibrosis degree of the non-alcoholic fatty hepatic fibrosis mice, and has a development prospect for serving as the medicine of combination of non-alcoholic fatty hepatic fibrosis and insulin resistance.

The invention belongs to the field of health care products, and in particular relates to an anti-alcohol and liver-protecting agent containing chicory nutritional components and a preparation method thereof. The hangover-protecting agent is prepared from chicory oligopeptide, chicory coumarin, traditional Chinese medicine extract, honey and deionized water according to a certain ratio, wherein the chicory oligopeptide and chicory coumarin are extracted from chicory root, Chicory oligopeptides are rich in amino acids such as alanine and leucine, which can promote the production of coenzyme NAD+ of alcohol dehydrogenase, which is beneficial to the catabolism of ethanol in the body, inhibits the increase of ethanol in the blood, and achieves the purpose of hangover; chicory Coumarin can speed up cell repair and has obvious protective effect on liver cells. The traditional Chinese medicine extract is prepared by extracting kudzu root flower, kudzu root, panax notoginseng, milk thistle, chrysanthemum, citrus aurantii and nutmeg. The invention can inhibit the gastrointestinal absorption of alcohol through the mutual compatibility of the effective components, accelerate the metabolism of the alcohol, reduce the damage of the alcohol to the liver cells, and can play a significant effect of sobering up and protecting the liver.

The invention discloses reproterol and novel application of its derivatives in the preparation of products for preventing and / or treating fatty liver. Experiments prove that by treating a fatty liver model rat with reproterol, it is possible to significantly relieve hepatic fatty degeneration, relieve hepatic lipid droplet accumulation and decrease the content of hepatic triglyceride. The reproterol is significant to the prevention and / or treatment of fatty liver.