290results about How to "Lower triglyceride levels" patented technology

The present invention provides compositions comprising therapeutic nucleic acids such as interfering RNA that target apolipoprotein C-III (APOC3) gene expression, lipid particles comprising one or more (e.g., a cocktail) of the therapeutic nucleic acids, methods of making the lipid particles, and methods of delivering and / or administering the lipid particles (e.g., for the treatment of lipid diseases or disorders such as atherosclerosis or a dyslipidemia such as hypertriglyceridemia or hypercholesterolemia).

The invention relates to an intestinal nutrient preparation, in particular to an intestinal nutrient preparation which is fit for Asian people nutrient support and has balanced medical effect, which comprises carbohydrate, plant protein, fat, vitamin, prandial fiber, emulsifying thickener, sodium nutrition, calcium nutrition, phosphor nutrition, kalium nutrition, magnesium nutrition, ferrum nutrition, zinc nutrition, iodine nutrition, selenium nutrition, cuprum nutrition, chromium nutrition, manganese nutrition, balsam pear powder, etc.

The preparation method of girasole beverage includes three technological process steps: 1. preparation of girasole hydrolyzate; 2. preparation of osmanthus flower extract; and 3. blending, packaging and sterilizing. The girasole hydrolyzate, osmanthus flower extract, phosphoric acid and citric acid are mixed according to the mixing ratio of 100:(10-12):3:(4-6), then water is added according to the ratio of the above-mentioned mixed material liquor and water of 1:(50-60), uniformly stirred, bottled, capped and sterilized so as to obtain the invented product with rice nutrients and several health-care functions of reproducing bifidobacteria in human body, inhibiting the growth of intestinal salmonella and spilage organism, raising immunity of human body and reducing blood-lipid, etc.

PCT No. PCT / JP96 / 02596 Sec. 371 Date Mar. 12, 1998 Sec. 102(e) Date Mar. 12, 1998 PCT Filed Sep. 12, 1996 PCT Pub. No. WO97 / 10224 PCT Pub. Date Mar. 20, 1997This invention provides new benzoxazepine compounds represented by the formula: [wherein R stands for a lower alkyl group optionally substituted with a hydroxyl group, X stands for an optionally substituted carbamoyl group or an optionally substituted heterocyclic group having a deprotonatable hydrogen atom, R1 stands for a lower alkyl group and W stands for a halogen atom] having activities of lowering chlesterol-level and lowering trigluceride-level, and being useful for prophylaxis and therapy of hyperlipidemia.

The invention relates to methods identify or characterize compounds that can be used to treat specified clinical disorders such as hyperglycemia and type 2 diabetes. Compounds that can be used in these methods include 4α-fluoro-17α-ethynylandrost-5-ene-3β,7β,17β-triol, 4α-fluoro-17α-ethynylandrost-5-ene-3β,7α,17β-triol, 4α-fluoro-17α-ethynylandrost-5-ene-3α,7β,17β-triol and 4α-fluoro-17α-ethynylandrost-5-ene-3β,17β-triol-7-one.

The present invention includes compositions and methods of making and using a dietary supplement manufactured from one or more natural polysaccharides previously incubated with a probiotic bacteria in a bioreactor system, wherein the bacteria process the polysaccharides and the resulting processed polysaccharide are provided in the nutritional supplement.

The invention relates to methods identify or characterize compounds that can be used to treat specified clinical disorders such as hyperglycemia and type 2 diabetes. Compounds that can be used in these methods include 4α-fluoro-17α-ethynylandrost-5-ene-3β, 7β,17β-triol, 4α-fluoro-17α-ethynylandrost-5-ene-3β,7α,17β-triol, 4α-fluoro-17α-ethynylandrost-5-ene-3α,7β,17β-triol and 4α-fluoro-17α-ethynylandrost-5-ene-3β,17β-triol-7-one.

The invention relates to a Chinese herb medicinal additive for preventing tilapia fatty liver disease. The Chinese herb medicinal additive is characterized by comprising the following components in part by weight: 8 to 10 parts of mung bean, 1 to 3 parts of liquoric root, 1 to 3 parts of gentian, 1 to 3 parts of raw gardenia, 1 to 3 parts of baical skullcap root, 1 to 3 parts of bupleurum, 2 to 5 parts of rehmannia root, 1 to 3 parts of plantain herb, 1 to 3 parts of virgate wormwood herb, 1 to 3 parts of indigowoad root, 1 to 3 parts of Mongolian dandelion herb, 2 to 5 parts of feverfew, 1 to 3 parts of turmeric root-tuber and 1 to 3 parts of oriental waterplantain rhizome. The Chinese herb medicinal additive has the advantages of capacities of obviously reducing liver weight / body weight and fat content of muscle and liver of the tilapia, reducing glutamic-oxalacetic transaminase activity, glutamic-pyruvic transaminase activity, total cholesterol content and triglycercide content in tilapia serum, protecting liver cells from the damage of factors such as nutritional factors, environmental factors and the like and effectively preventing nutritional fatty liver disease in the breeding process of the tilapia, convenient addition and use, capacity of being added in a commercial feed directly, synergistic effect of the components and other additive components in the commercial feed, improvement on the disease resistance of the tilapia, stable raw material source, low cost, simple production process and easy industrialized production.

Compositions, methods, and kits useful for treating hyperlipidemic conditions are provided herein. Such compositions can contain synergizing amounts of nicotinic acid, nicotinamide riboside and / or nicotinic acid metabolites in combination with leucine and / or a leucine metabolite, with or without resveratrol.

There is provided in accordance with an exemplary embodiment of the invention a method of treating diabetic patients comprising measuring a triglyceride level in a diabetic patient and applying a diabetes treatment according to the triglyceride level. Optionally, there is provided a method of screening. Alternatively or additionally, there is provided a method of weight loss. Alternatively or additionally, there is provided a method of relatively reducing HOMA-IR levels. Alternatively or additionally, there is provided a method of relatively reducing blood pressure. An exemplary device to apply the treatment is described.

The invention relates to the field of microorganisms and discloses lactobacillus plantarum with a weight reducing function and application thereof. The lactobacillus plantarum 1701 strain is separatedfrom a yogurt powder sample collected from rural areas of Shigatse in the Tibet Autonomous Region. The strain is preserved in the China General Microbiological Culture Collection Center on October 23, 2019, and the microorganism has the preservation number of CGMCC NO.18728. The lactobacillus plantarum 1701 has excellent tolerance and adhesion, can remarkably reduce the weight of a rat, reduce fat accumulation in a body, reduce the viscera ratio and body fat ratio, reduce the leptin level and reduce blood lipid and can be used in medicines, health-protecting products and health foods for preventing and treating obesity. Furthermore, the strain still has a weight reducing function after inactivation, thus having rich product mode, wide application range, high product stability and long preservation period.

Disclosed is a antihypelipidemic and antihyperglycemic health food for preventing diseases including cardiovascular disease, diabetes, adjusting internal secretion, resisting osteoporosis and cancer, and beauty treatment. The raw materials include soybean powder 15-30 parts, pumpkin powder 15-30 parts, soybean isoflavones 0.5-1.5 parts, soybean saponin 2-5 parts, astragalus root 10-20 parts, wolfberry fruit 10-15 parts, kudzuvine root 10-15 parts, Chinese yam 10-15 parts, lotus plumule 6-10 parts, Siberian solomonseal rhizome 6-10 parts, cassia seed 6-10 parts, lily 5-8 parts, mulberry leaf 5-8 parts and ginseng 3-5 parts.

The present invention relates to a method for increasing in a baked product, after baking, the level of water-soluble arabinoxylan with an average degree of polymerization ranging from 5 to 50, preferably ranging from 5 to 35, more preferably ranging from 5 to 25, said method comprising the steps of:—Preparing a dough for a baked product with flour, a mixture of flours or a mixture of flour (s) with milling fractions having a total arabinoxylan content of at least 2.0%, preferably at least 2.5%, and—Adding to said dough an enzyme preparation comprising at least one thermophilic endoxylanase in an amount at least 2-fold higher, preferably at least 3 to 6 times higher or even 10 times higher than the dose conferring 90% of the maximal bread volume increase obtained by addition of such enzyme preparation to the recipe of said baked product. Advantageously with said method baked products can be obtained that have a level of arabinoxylan of the desired type of at least 1.7%, more preferably at least 1.75%, such as at least 1.8%, 1.9% or 2.0%. The present invention further relates to baked products obtainable by this method, and to an improver and a dough which may be used for the preparation of such products. Baked products according to the invention advantageously have improved health benefits.

The invention discloses a biologic emulsifier for livestock feed. The biologic emulsifier is characterized by being prepared by two or more than two of sophorolipid, rhamnolipid and trehalose. The sophorolipid, the rhamnolipid and the trehalose and the like in the emulsifier are all secondary metabolites generated by microbial fermentation, can be naturally metabolized and degraded, do not cause residues in animal bodies, and do not influence quality of animal products. The biologic emulsifier can remarkably improve livestock fat digestion utilizing rate, improves feed reward, reduces livestock blood cholesterol and triglyceride, remarkably improves livestock production performances, improves carcass quality, improves body immune function, reduces morbidity and mortality, and remarkably improves economic returns.

Provided is a method of monitoring the treatment of Gaucher disease with specific pharmacological chaperones using systemic and / or cellular surrogate markers. Also provided is a new biomarker that may be used to monitor the progress of such treatment.

The present invention relates to the use of a DGAT1 inhibitor, or a pharmaceutically acceptable salt or ester thereof, for the prevention, delay of progression or treatment of a disease or condition which is selected from chylomicronemia syndrome, familial chylomicronemia syndrome and Type V hyperlipoproteinemia. The present invention further relates to the use of a pharmaceutical composition comprising a DGAT1 inhibitor, or a pharmaceutically acceptable salt or ester thereof, for the prevention, delay of progression or treatment of a disease or condition which is selected from chylomicronemia syndrome, familial chylomicronemia syndrome and Type V hyperlipoproteinemia.

The invention relates to medicine and food homologous plant concentrated juice which is prepared from the following raw materials in parts by weight: 2-45 parts of hovenia dulcis thunb, 1-25 parts of kudzuvine root, 1-20 parts of dandelion, 1-16 parts of liquorice, 1-16 parts of hawthorns and 1-10 parts of pericarpium citri reticulatae. The invention also relates to a preparation method for the medicine and food homologous plant concentrated juice. The preparation method comprises the following steps of (1) concentrated juice extraction, (2) alcohol precipitation and (3) water precipitation. The medicine and food homologous plant concentrated juice disclosed by the invention has the beneficial effect of effectively alleviating alcoholic liver injury.

A method of treating metabolic syndrome in a human diagnosed with metabolic syndrome by administering a therapeutically effective amount of fenofibrate over a treatment period. The results can include identifying a human as not having clinical metabolic syndrome after treatment, as compared to having metabolic syndrome before treatment.

Compositions, methods, and kits useful for treating hyperlipidemic conditions are provided herein. Such compositions can contain synergizing amounts of nicotinic acid, nicotinamide riboside and / or nicotinic acid metabolites in combination with leucine and / or a leucine metabolite, with or without resveratrol.

The invention discloses preparation and application of polyunsaturated fatty acid containing rich conjugated linoleic acid and belongs to the technical field of polyunsaturated fatty acid extraction and steady-state treatment of grease. A preparation method comprises the following steps: (1) preparing mixed fatty acid by utilizing an enzymolysis method; (2) enriching the polyunsaturated fatty acid by utilizing a urea-inclusion method; (3) enriching the conjugated linoleic acid by combining a super-critical CO2 extraction method and an alkali isomerization method to finally obtain the polyunsaturated fatty acid containing the rich conjugated linoleic acid, wherein the content of the conjugated linoleic acid reaches 90 percent or more and a product contains other polyunsaturated fatty acid at the same time so that the structure of the product is more reasonable. By adopting a method for preparing microcapsules or emulsion, the polyunsaturated fatty acid containing the rich conjugated linoleic acid is subjected to stabilization treatment, so that the storage stability of the product is improved and the storage period can reach 24 months; meanwhile, the bioavailability of the polyunsaturated fatty acid is improved and the polyunsaturated fatty acid is more easily digested and absorbed by human bodies.

The invention provides hericium erinaceus and konjak tofu and a making method thereof. The hericium erinaceus and konjak tofu is made from, by weight, 48.1-48.2% of water, 4.9-5% of textured soybean protein, 10.4-10.5% of edible oil, 19.4-19.5% of isolated soybean protein, 14.97-14.98% of hericium erinaceus powder, 0.58-0.59% of edible salt, 0.19-0.20% of starch, 0.019-0.02% of konjak purification powder, 0.019-0.020% of I+G, 0.97-0.98% of white granulated sugar, 0.019-0.020% of yeast powder, 0.019-0.020% of TG enzyme and 0.0058-0.0059% of natamycin. The nutritional value of the hericium erinaceus and konjak tofu is improved, the immunologic function of the human body can be enhanced, the preparation technology is simple, the shelf life of the made tofu is long, and the tofu is convenient to eat.

The invention discloses a mixed culture fermentation tea bag and a preparation method thereof. Bacillus natto and lactobacillus plantarum are used as fermentation cultures, culture fermentation is carried out in raw materials with jerusalem artichoke leaves, celery leaves and purslane leaves as main substrates, aftertreatment and bagging are performed, and the fermentation tea bag is obtained. The tea soup is mellow in taste, strong in fragrance and rich in nutrition, can achieve the health care effect while obtaining bacillus natto and lactobacillus plantarum, and is beneficial to improving the intestinal function, adjusting blood glucose and preventing arteriosclerosis, heart disease , diabetes and cancer.

The invention discloses a high-protein, low-sugar and high-lipid ketogenic meal replacement cake and a manufacturing method thereof. The formula comprises the following by mass parts: 16-35 parts of almond powder, 0-8 parts of flaxseed powder, 16-25 parts of protein powder, 10-25 parts of edible oil, 8-16 parts of dietary fiber, and 6-15 parts of erythritol. The formula of the invention is not only suitable for obese people and hyperglycemic people, but can also regulate the gastrointestinal health of the human body, and can increase the muscle mass of the body and improve the health of the user. Grease, erythritol and cream are mixed firstly, and then eggs and dietary fiber are added, and finally the mixed solid powdery material is added. The method can completely dissolve the dietary fiber, so that the produced cakes have delicate texture without obvious rough feelings.

The invention relates to the field of microorganisms, and discloses lactobacillus fermentum with a weight reducing function and an application of the lactobacillus fermentum. The lactobacillus fermentum is named as WHH3906, is separated from butter collected in Tibet Autonomous Region in China, is preserved in China General Microbiological Culture Collection Center on March 13, 2020, has a preservation number of CGMCC NO.19472, and is classified and named as lactobacillus fermentum. The lactobacillus fermentum strain can effectively reduce serum leptin level to recover leptin sensitivity of anorganism, effectively prevent and treat obesity, relieve non-alcoholic fatty liver and relieve chronic inflammation. After being compounded with lactobacillus plantarum 1701, the lactobacillus fermentum can synergistically relieve chronic inflammation.

The invention relates to the application of effective component forsythin in preparation of tablet to swallow for curing adiposis and Health-care food. Forsythin is an effective component abstracted from fruit or leaf of Chinese medicine forsythia, it is mixed with organic or inorganic, solid or liquid excipient to form solid preparation to swallow such as tablet, capsule, particle, powder and pill, and it can also be added into food to produce Health-care food. The poisonous experiment has proved that the LD50 of rat is 8.30g / Kg, it has smaller poisonous side effect, and medicine effect experiment has proved that it can reduce the weight rate of growth, coefficients of fat and lee's index of nutritional fat rat, make the cell of fat rat become smaller by decreasing cholesterin and triglyceride content in serum, so it has better effect for nutritional fat rat.

Compositions comprising the peroxisome proliferator-activated receptor alpha (PPARα)-ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0 / 18:1-GPC) are disclosed. These compositions may be used for the prophylaxis and treatment of PPARα-related liver disorders including, but not necessarily limited to, fatty liver disease, to lower lipid and triglyceride levels, and to increase high density lipoprotein levels in animals. Foods modified with 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0 / 18:1GPC) may be used to improve the metabolism of animals.

A composite medicine for treating cardiovascular and cerebrovascular diseases is proportionally prepared from gingko leaf, or its extract, or its general flavone, or the ginkalide and kakonein.

The invention discloses a preparation method of medlar milk, comprising the following steps: (1) filtering and purifying, namely filtering and purifying high quality raw milk; (2) preheating, namely preheating the filtered and purified milk to 32-38 DEG C, slowly adding a medlar extract equivalent to 10-25% of the weight of the milk and a compound stabilizer equivalent to 0.3-0.7% of the weight of the milk while stirring, fully stirring until the mixture is uniform, and filtering; (3) sterilizing and homogenizing, namely sterilizing and homogenizing the preheated filtered milk by virtue of a sterilizing machine and a homogenizing machine; and (4) cooling and filling, namely cooling the sterilized and homogenized milk and then filling. The preparation method provided by the invention has the advantages that the technological process is scientific, the loss of nutritional ingredient is less, and the prepared milk finished product has a certain nourishing effect.