33results about How to "Improve liver damage" patented technology

The invention discloses Bifidobacterium adolescentis CCFM1061, its fermented food and a preparation method of bacterial preparations. Bifidobacterium adolescentis CCFM1061 can significantly improve liver damage in patients with non-alcoholic fatty liver disease, reduce serum ALT levels, and reduce hepatic steatosis and hepatic ballooning. lesions and hepatic lobular inflammation; it can significantly alleviate the increase in serum total cholesterol, blood sugar, liver triglyceride and low-density protein cholesterol caused by high-fat diet in patients with nonalcoholic fatty liver disease; at the same time, it can significantly improve liver It can significantly increase the expression of Nrf2 gene in fatty liver cells; improve the fasting blood sugar in type 2 diabetic mice; in addition, Bifidobacterium adolescent CCFM1061 has a strong adsorption capacity for PFOA, which reduces the absorption of PFOA in the body and has the effect of relieving PFOA toxicity capacity.

The invention discloses an application of clostridium butyrate in a preparation for prevention and treatment or adjuvant therapy of hyperglycemia and belongs to the technical field of prevention and treatment of diabetes. According to the application, during the prevention and treatment or adjuvant therapy of the hyperglycemia, butyric acid is produced in an intestinal tract, meanwhile, florae of the intestinal tract are changed, signals are sent to an ileum, a liver, a pancreatic gland and a brain by a portal vein blood sugar sensor, the ileum is promoted to secrete (GLP-1) glucagon-like peptide-1, the gluconeogenesis of the liver is lowered, pancreatic beta cells are protected, the secretion of insulin of the pancreatic gland is promoted, and thus, the action of reducing blood sugar is exerted. The clostridium butyrate is a medicine which has been proven by clinical drug trials and can be directly taken orally.

The invention discloses the use of inulin and its derivatives in the preparation of drugs for the prevention and treatment of fatty liver damage, which can alleviate the lipid metabolism disorder of liver cells, and can inhibit the levels of TG and TC in liver cells induced by oxLDL and the Fat drop accumulation; can prevent and treat liver damage caused by alcoholic fatty liver, effectively improve liver function and abnormal blood lipids; can prevent and treat liver damage caused by non-alcoholic fatty liver, effectively improve liver function and blood lipids Abnormal situation, compared with many existing lipid-lowering drugs, has the characteristics of less toxic and side effects and better curative effect, and has the potential to be developed into a natural and low-toxic lipid-lowering drug with clinical application value.

The invention discloses a preparation method and application of a class of continuation alkane-type macrocyclic diterpene compounds. For the first time, the present invention uses the continuation alkane-type macrocyclic diterpenoids in the preparation of anti-cholestasis medicines. The results of cell experiments show that the sacronane-type macrocyclic diterpene compounds in the present invention have good pregnane X receptor agonist activity and anti-cholestasis activity, and are expected to be developed into novel pregnane X receptor agonists and anti-cholestatic agents. Cholestatic drugs.

The invention relates to a traditional Chinese medicine composition for achieving liver-protection and pain-easing effects and a preparation method of the traditional Chinese medicine composition. The preparation method comprises the steps of taking eight medicinal materials including Desmodium styracifolium, corn stigma, pyrrosia lingua, Abrus cantoniensis Hance, Poria cocos, plantain herb, Lygodium japonicum Sw and lalang grass rhizome, wherein the Desmodium styracifolium, the pyrrosia lingua and the Abrus cantoniensis Hance are extracted by an alkaline aqueous solution, and the lalang grass rhizome, the Poria cocos, the plantain herb, the corn stigma and the Lygodium japonicum Sw are extracted by water; and finally mixing fluid extracts obtained by the two extraction methods. The animal pharmacological experiments and clinical test results prove that the traditional Chinese medicine composition has excellent liver-protection and pain-easing effects superior to the prior art when being used for treating lithiasis in urinary system.

The invention relates to a capsule for improving liver damage and body fatigue and a preparation method thereof, belonging to the technical fields of medical technology and health food. The capsule of the present invention comprises the following components in parts by weight: 200-500 parts of reduced glutathione, 30-250 parts of turmeric extract, 30-200 parts of taurine, 38-170 parts of filler, 40 parts of binder ~60 parts, disintegrant 10~26 parts, lubricant 2~14 parts. The capsule of the present invention uses reduced glutathione, turmeric extract, and taurine as main raw materials, can increase the level of glutathione in the body and make it reach a steady state, and effectively improve liver damage and body fatigue; the capsule of the present invention The capsule formula is scientific, convenient to take, and has stable and remarkable efficacy.

A drug composition for treating chronic liver diseases, consists of: Astragalus Astragalosides and Glycyrrhiza Acid by weight ratio of 3˜6:1. By testing and validating with classic animal model, the results confirmed that the drug composition of the present invention can significantly reduce the collagen content of rat liver, and reduce liver fibrosis and liver injury, wherein the effect is better than the effect of each component alone. The drug composition of the two components or ingredients can improve the anti-hepatic fibrosis, effectively prevent liver fibrosis and promote the development of liver fibrosis reversal, and thus can be used for the treatment and prevention of various chronic hepatitis, liver fibrosis, cirrhosis and other illnesses.