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Mammalian viral vectors and their uses

InactiveUS6255071B1Stable episomal maintenanceMaintain relatively stableSugar derivativesMicrobiological testing/measurementRetroviral provirusMammal
The present invention relates to methods and compositions for the elucidation of mammalian gene function. Specifically, the present invention relates to methods and compositions for improved mammalian complementation screening, functional inactivation of specific essential or non-essential mammalian genes, and identification of mammalian genes which are modulated in response to specific stimuli.In particular, the compositions of the present invention include, but are not limited to, replication-deficient retroviral vectors, libraries comprising such vectors, retroviral particles produced by such vectors in conjunction with retroviral packaging cell lines, integrated provirus sequences derived from the retroviral particles of the invention and circularized provirus sequences which have been excised from the integrated provirus sequences of the invention. The compositions of the present invention further include novel retroviral packaging cell lines.
Owner:COLD SPRING HARBOR LAB INC

Airborne wind turbine electricity generating system

An airborne system for producing electricity from wind energy includes a shaft, at least two turbines rotatably mounted to the shaft and arranged to rotate independent of one another and in opposite directions when subjected to the same wind, and generators which convert rotation of the turbines into electricity. The magnitude of electricity generation by the generators is related to the magnitude of torque induced by the generators on the shaft, and the electricity generation by the generators may be controlled such that torques induced on the shaft by the generators is controlled such that a sum of torques induced on the shaft is substantially zero. A lifting structure generates a lifting force to lift the turbines to a desires altitude, and an anchoring system anchors the turbines relative to the ground. Generated electricity is conducted to users, to electricity storage, or to processing components.
Owner:MELLER MOSHE

Wave-power generation system

Disclosed is a wave-power generation system. The system includes a stationary frame, a float structure installed to the stationary frame, a rotary shaft coupled to a generator and rotatably installed to the stationary frame, a rotary drive coupled to the rotary shaft of the generator via a one-way clutch, a three-node link rotatably installed at a point P of the stationary frame, a float installed to one end of the three-node link, a rope having one end coupled to the other end of the three-node link and the other end wound around the rotary drive, a flywheel installed to the rotary shaft, and a resiliently recovering member having one end coupled to the stationary frame and the other end coupled to the rotary drive.
Owner:YIM MYUNG SHIK
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