The invention mainly relates to the technical field of vehicle product processing, and discloses a high-elasticity anti-aging vehicle door sealing strip, which is prepared from the following raw materials: polyether polyol, polyurethane, a foamed silica gel, polyimide, isooctyltriethoxysilane, phthalate, azodicarbonamide, tricalcium phosphate, nanometer titanium dioxide, and nanometer zinc oxide.According to the present invention, the high-elasticity anti-aging vehicle door sealing strip has characteristics of strong elasticity, strong compression deformation resistance, water resistance, dust resistance, sound resistance, thermal insulation and excellent aging resistance, and can effectively delay the corrosion of ultraviolet rays and air pollutants, and the service life can be prolongedto 6 years, such that the replacement frequency of the vehicle door sealing strip can be significantly reduced, the resources can be saved, the environment can be protected, and the use cost of the vehicle can be reduced; and the polyether polyol and the polyurethane are slowly mixed and heated, such that the raw materials are fully grafted so as to improve the elasticity and the strength of thesealing strip.