The invention discloses a three-dimensional vibration insulation and reduction device and method. According to the three-dimensional vibration insulation and reduction device, horizontal vibration is insulated through a rubber support on the lower portion, and vertical vibration of vertical rail transit is insulated through a vertical vibration insulation device on the upper portion. The horizontal rigidity of the rubber support is small, under the action of an earthquake, transfer of the earthquake action to an upper building structure is reduced, and thus, horizontal vibration is insulated. The vertical vibration insulation device adopts disc spring sets, the vertical rigidity is small, and under the action of ground vertical vibration waves caused by metro operation, transfer of vertical vibration to the upper building structure is stopped. Meanwhile, through the deformation and reset processes of the disc spring sets, vertical vibration applied to the structure is reduced, a part of vibration energy is consumed through friction resistance, thus, the structure is stressed more reasonably, the structure safety is guaranteed, and accordingly vertical vibration of vertical rail transit is insulated. The three-dimensional vibration insulation and reduction device has the characteristics of being simple in structure, stable in vibration insulation and reduction performance, reliable and durable.