87results about How to "Good self-emulsifying performance" patented technology

Stable solutions of lipophilic drugs, such as cyclosporin, forming a polar lipid self-emulsifying drug delivery system. The solutions can include lipophilic drugs, such as cyclosporin, dissolved in a polar lipid, such as having a C₆-C₁₂ fatty acid monoglyceride content of at least about 50%, surfactants and triglycerides. The composition forms a fine emulsion on exposure to water. The encapsulated dosage form of this composition needs neither a hydrophilic component nor air-tight blister packaging, and is particularly suitable for oral administration.

The invention discloses lutein ester microcapsule powder and a preparation method thereof. The preparation method comprises the following steps of: preparing an oil phase solution and a water phase solution respectively, and mixing and emulsifying the oil phase solution and the water phase solution; and non-water raw materials comprise the following components in part by weight: 1 part of lutein ester crystal, 0.05 to 0.1 part of oil phase antioxidant, 0.02 to 0.1 part of oil phase emulsifying agent, 0.05 to 1 part of plant oil, 0.5 to 25 parts of wall material, 0.1 to 0.5 part of water phaseemulsifying agent, 0.05 to 1 part of water phase antioxidant, and the balance of filler. In the preparation method for the lutein ester microcapsule powder, the oil-soluble lutein ester is fully dispersed in cold water in the form of sub nanometer particles, and the product can be self-emulsified in water, and is good in instant capacity and self-emulsification capacity, and high in stability, and has uniform and durable color; and the phenomena of oil floating, precipitation, adhesion to a bottle wall and the like are avoided during application. Organic solvents are not introduced in the powder, so solvent residues are avoided in the product. The production process is environment-friendly, simple and practicable, expensive equipment is not needed, and the microcapsule powder can be industrially produced easily and conveniently.

The invention relates to the field of textile finishing agent, in particular to supersoft hydrophilic block silicone oil compound and a preparation method thereof. The supersoft hydrophilic block silicone oil compound is composed of cations of the structural formula, wherein the n1 is the number of 5 to 10, the R is polyether group, and the degree of polymerization ranges from 3 to 50. The supersoft hydrophilic block silicone oil compound is applicable to handle finishing of fabric knitted by one or multiple fibers of cotton, dacron, chinlon and acrylic fibers and has softness, smoothness and looseness effects superior to those of amino-modified silicone oil, has excellent stability in acid and alkali resistance, electrolyte resistance, high temperature resistance, shearing resistance and the like and thoroughly solves the problems of easy demulsification, floating oil, roll banding, difficulty in refinishing and the like.

The invention discloses a self-emulsifying water-borne epoxy resin curing agent and a preparation method thereof. The method comprises the following steps: S1, mixing and reacting single polyamine with epoxy resin according to the molar ratio of (1.8:2) to (2.1:1), so as to obtain an intermediate addition product; S2, blocking the intermediate addition product by adopting a single epoxy compound, so as to obtain the self-emulsifying water-borne epoxy resin curing agent; controlling the molar ratio of the single polyamine to the epoxy resin within a certain range; blocking the addition product by adopting the single epoxy compound, so as to obtain the curing agent which meets the water soluble requirements and has excellent application performance. The self-emulsifying water-borne epoxy resin curing agent has a good adaptive phase and coating property when being applied to a coating. The mode of neutralizing and blocking by adopting an organic acid when the self-emulsifying water-borne epoxy resin curing agent is prepared at present is abandoned, the process is simplified, and the problems that the cation water-soluble epoxy curing agent neutralized and prepared by adopting the organic acid is sensitive to pH value, and the unstability is generated when a basic dye and a filler are used together are solved.

The invention discloses baby skin moistening and protecting cream which comprises the following ingredients in percentage by weight: 2.15085-41.2% of plant extracts, 0.5-8% of at least one of caprylic triglyceride and capric triglyceride, 0.2-3% of sorbitan olivate, 0.5-10% of glycerinum, 0.2-3% of cetearyl olivate, 0.2-3% of glyceryl stearate, 0.1-5% of sorbitol, 0.05-0.3% of xanthan gum, 0.3-0.8% of tocopherol, 0.0001-0.5% of hyaluronic acid, 0.5-3% of erythritol and the balance of water, wherein the plant extracts include avocado butter, olea europaea fruit oil, rice chaff oil, wheat germ oil, oat germ oil, a paeonia suffruticosa root extract and rosmarinus officinalis leaf oil. The baby skin moistening and protecting cream is prepared from various plant extracts and animal extracts and chemicals with small skin irritation, so that the cream has a good effect of moistening and protecting baby skin and has no irritation and toxicity to the baby skin.

The invention discloses a method for preparing composite water-based polyurethane. The method comprises the following steps of: adding polyether, epoxy resin, toluene diisocynate and rude MdI into a kettle, then adding a catalyst into the kettle, and preheating and prepolymerizing the mixture; measuring -NCO value, adding dimethylopropionic acid, after reacting the mixture, measuring -NCO value again; reducing the temperature, adding acetone, stirring the mixed solution, discharging the obtained product; placing the obtained product into a dispersion barrel, adding triethylamine into the dispersion barrel, stirring the mixture, adding water, and dispersing the mixed solution at a high speed; after dispersing the mixed solution uniformly, adding ethidene diamine, performing a chain extending reaction, and then stirring the obtained solution at a reduced speed; sealing and standing the obtained solution, then filtering the obtained solution and discharging the filter. The method overcomes the shortage of short-time use after the mixing of two components because the conventional oil polyurethane uses an irritant solvent, reduces waste and protects environment, has the advantages of non-toxicity and light smell by taking water as a solvent, and makes an adhesive achieve the adhesive strength by heating and activating the adhesive when clothes are bonded so as to achieve effect of good hand feeling after bonding and good water washing property.

The invention belongs to the technical field of preparation of curing agents, and discloses an epoxy resin water-permeable material curing agent and a preparation method and application thereof. The curing agent is prepared from the following components in percentage by mass: 50-80 percent of ricinoleic acid and/or a polymer thereof, and 20-50 percent of fatty polyamine, alicyclic polyamine or polyoxypropylene polyamine containing a polypropylene oxide chain segment. The curing agent provided by the invention is a waterborne curing agent, has superior curing performance, and can be cured at the room temperature; a cured product has superior water permeability and air permeability, and can be applied to curing of an epoxy water-permeable material to prepare an epoxy ceramic forming mold or an epoxy water-permeable material. A fatty polyamine, polyoxypropylene polyamine or alicyclic polyamine curing agent is modified, so that the curing agent contains hydrophobic long-chain alkyl, hydrophilic hydroxyl, an amino group, acylamino and an ester group, has self-emulsifying performance, and can also be taken as a curing agent; a gap and a channel are formed between the epoxy resin and inorganic filler through a hydrophobic group, so that the obtained epoxy material has superior water permeability and air permeability.

The invention relates to a butylphthalide controlled release preparation and a preparation method thereof. Drugs can be uniformly released at a constant speed, and release of liquid drugs from the controlled release preparation in a liquid form is achieved.

The invention relates to a biodegradable aqueous emulsion-type polylactic acid adhesive and its preparation method. As a water dispersible emulsion, every 100 parts by weight of the adhesive at least contains 5-45 parts by weight of a polyethylene glycol grafted polylactic acid copolymer, 5-40 parts by weight of vinyl acetate grafted starch, and 0.5-30 parts by weight of an ethylene-vinyl acetatecopolymer. The aqueous emulsion-type polylactic acid adhesive provided in the invention is biodegradable, has high bonding fastness, adjustable filter rod hardness as well as good moulding performance, and simultaneously has filter rod adsorption enhancing and harm reduction performances.

The invention discloses a phospholipid-containing flavonoid polyphenol drug self-emulsifying composition. The composition comprises a flavonoid polyphenol drug, free phospholipid, an oil phase, an emulsifier and a co-emulsifier, and the flavonoid polyphenol drug comprises one or more materials selected from baicalein, procyanidine, quercetin, curcumin and resveratrol. The composition has the beneficial effects of good stability, high drug loading capacity, higher bioavailability and the like.

A preparation method for phosphatide oiling retaining agent takes maleic anhydride and acrylic acid as the raw materials to synthesize an acrylic-maleic anhydride low polymer, acetic acid peroxide is used to oxidize and concentrate bean phosphatide to prepare phosphatide hydroxide, then the acrylic acid-maleic anhydride polymer is condensated with the phosphatide hydroxide to prepare the phosphatide oiling retanning agent.

An object of the present invention is to provide a polyglycerol medium-chain fatty acid ester-containing composition capable of forming a water-in-oil microemulsion, the microemulsion being capable of solubilizing a large amount of water, and the composition having excellent dispersibility and self-emulsifiability in water, and cosmetics comprising the composition. The present invention relates to a polyglycerol medium-chain fatty acid ester-containing composition comprising a polyglycerol medium-chain fatty acid ester formed by esterification of a medium-chain fatty acid having 6 to 10 carbon atoms and a polyglycerol having an average degree of polymerization of 3 or more and less than 100, and a nonionic surfactant; and cosmetics comprising the polyglycerol medium-chain fatty acid ester-containing composition as defined above.

The invention is concerned with a kind of Adefovir Dipivoxil self-emulsification capsule preparation and its produce method. Adefovir Dipivoxil is anti-hepatitis B virus agent with instability and the biology utilization ratio of existing preparation is low with complicated process and big harmless of dust. Mix the middle solution with Adefovir Dipivoxil in the amount of prescription and oil, dispose the middle solvent by extrusion method after rotating-film evaporating technique, add emulsifying agent, heat in water with constant temperature or ultrasonographic to get even and transparent liquid and produce into soft capsule or hard capsule. The production has nice stability, high biology utilization ratio and easy for using.