The invention relates to a board-mode program-controlled voltage bias test circuit of a large-scale digital integrated circuit. The program-controlled voltage bias test circuit comprises a power supply module, a first numerical control potentiometer, a second numerical control potentiometer, a first relay, a second relay, a third relay, a first resistor, a second resistor, a third resistor and aninstruction control module, wherein a first control end of the power supply module is connected with an adjustable resistor end of the first numerical control potentiometer, a second control end of the power supply module is connected with an output end of the first relay, a first input end of the first relay is connected with an adjustable resistor end of the second numerical control potentiometer, and a first input end of the first relay is connected with an output end of the second relay. According to the invention, through cooperation of the power supply module, the numerical control potentiometer, the relay, the resistor and the instruction control module, automatic control of bias voltage in a large-scale digital circuit board mode bias test is realized, a large-size special instrument does not need to be carried, and thus the portability is better.