34 results about "Scarring skin" patented technology

The invention discloses a scar repair material. A preparation method comprises the following steps of: dissolving water-soluble chitosan in water or dissolving chitosan with the deacetylation degree of 75 to 97 percent in an acetic acid aqueous solution under stirring, adding polyoxyethylene sorbitan monolaurate with an emulsifying effect and glycerin with a moisturizing effect, and uniformly mixing to obtain a transparent gel-like solution; and adding polydimethylsiloxane into the gel-like solution under homogenizing, and uniformly mixing to obtain the scar repair material. The scar repair material can actively and passively moisture skin, has a hydration effect on scar skin, has a good repair effect, has an effect of resisting and inhibiting bacteria, has a good effect of resisting and inhibiting the bacteria on the surfaces of scars and outside the scars, has an effect of accelerating skin wound healing, can have a good effect of repairing and protecting fine cracks on the surfacesof the scars, and can inhibit the secretion of collagen type I in keloid skin to reduce the proportion of the collagen type I or collagen type III.

A composition for promoting regeneration of tissue which has degenerated in a subject as a result of a disease or disorder and a method of using the composition is provided. The composition comprises a biodegradable acellular matrix, and passaged autologous fibroblasts substantially free of immunogenic proteins, e.g., culture medium serum-derived proteins, integrated within the matrix. The method of using the composition to promote regeneration of tissue involves placing the composition on a site of degenerated tissue in a subject so that the composition promotes tissue regeneration at the site. The composition and the method of its use have applications promoting regeneration of tissue (i) that has degenerated as a result of numerous diseases or disorders or (ii) that has a defect, including, but not limited to, defects of the oral mucosa, trauma to the oral mucosa (e.g., extraction of a tooth), periodontal disease, diabetes, cutaneous ulcers, venous stasis, scars of the skin, or wrinkles of the skin. Also provided is an injectable composition comprising any type of collagen and passaged autologous fibroblasts substantially free of immunogenic proteins, e.g., culture medium serum-derived proteins, for correcting defects in skin, such as wrinkles or scars, and for augmenting tissue in the subject, particularly facial tissue.

The invention discloses traditional Chinese medicine soap for removing scar. The traditional Chinese medicine soap is prepared from 10 to 20 parts by weight of folium artemisiae argyi, 20 to 30 parts by weight of pine bark, 7 to 15 parts by weight of radix clematidis, 10 to 15 parts by weight of safflower, 6 to 11 parts by weight of trogopterus dung, 6 to 11 parts by weight of Chinese gall, 5 to 10 parts by weight of red sage root, 10 to 15 parts by weight of radix lithospermi, 10 to 15 parts by weight of dark plum, 3 to 5 parts by weight of radix sophorae flavescentis, 5 to 10 parts by weight of rhizoma curcumae, 7 to 20 parts by weight of licorice root, 7 to 10 parts by weight of coconut oil, 7 to 10 parts by weight of palm oil, 7 to 10 parts by weight of ethanol and 10 to 15 parts by weight of sodium hydroxide. The traditional Chinese medicine soap is prepared from traditional Chinese medicines, can slowly care and remove scar in the daily life, does not stimulate patient scar skin and has high safety.

The invention relates to beauty soap. The beauty soap is formed by mixing and pressing traditional Chinese medicine composition and a soap base according to the mass ratio of 1 to 1-5. The traditional Chinese medicine composition is composed of, by weight, 1-10 parts of ginseng, 1-10 parts of jasmine flower, 5-12 parts of saposhnicovia divaricata, 10-15 parts of fructus lycii, 1-15 parts of red peony root, 1-12 parts of fritillary bulb, 1-15 parts of chamomile, 1-20 parts of rose and 1-11 parts of giant typhonium rhizome. The beauty soap can effectively remove dirt on skin, is moderate and free of harm to skin, has the functions of whitening, moisturizing, wrinkle removing and scar removing, and is suitable for patients with scarred skin and is free of toxic and side effects after long-term use.

The present invention relates to external skin products, in particular to drug-loaded nanofibers and their preparation methods and applications. The drug-loaded nanofiber contains nanofibers formed by auxiliary components and palmetine loaded on the nanofibers, and the content of the auxiliary components is 5-75g per gram of palmetine. The preparation method of drug-loaded nanofibers comprises: electrospinning the spinning solution containing palmetine and auxiliary components to obtain drug-loaded nanofibers. It also relates to the application of the drug-loaded nanofibers in the preparation of anti-scar skin external products. The drug-loaded nanofibers use palmatine as the active component, and the active component releases the drug effect continuously, promotes healing and anti-inflammation, regulates the growth and proliferation of cells, and then effectively inhibits the formation and growth of scars, and can be widely used in external skin products in, especially for dressings. The invention adopts a blending electrostatic spinning method to prepare drug-loaded nanofibers, the preparation process is simple, and the obtained drug-loaded nanofibers are continuous and uniform.

The invention discloses a thymosin β-4 ethosome and a preparation method thereof. The specific composition of the thymosin β-4 ethosome comprises: thymosin β-4 0.022%-0.043%, phospholipid 0.054%-0.084% , cholesterol 0.018% ~ 0.028%, anionic surfactant 0.02% ~ 0.04%, ethanol 10.10% ~ 30.30%, the rest is distilled water; it has the effect of increasing the transdermal absorption of drugs and enhancing the repair of scarred skin by thymosin β‑4 technical effect. And the preparation method of thymosin β-4 ethosome in the present invention, utilizes the mode that adds anionic surfactant and cholesterol to solve the stability problem of thymosin β-4 ethosome, adopts the thymosin that this preparation method obtains The β‑4 ethosome has high encapsulation efficiency, good stability, simple process and good economic benefits. Correspondingly, the present invention also protects the application of the thymosin β-4 ethosome in the field of scar repair.

The invention discloses a horizontal continuous casting crystallizer of a cast iron and a preparing method of cast iron proximate matter. The crystallizer comprises a crystallizer body; a collector nozzle type isolation ring is arranged at the front end of a high-purity graphite casting mold of the crystallizer body; according to the horizontal continuous casting crystallizer of the cast iron, the collector nozzle type isolation ring is arranged at the front end of the high-purity graphite casting mold, the blocking effect of the collector nozzle type isolation ring is used for forcing molten iron not to enter the high-purity graphite casting mold in a laminar flow manner, the molten iron must enter the high-purity graphite casting mold in a forced laminator flow manner, the high-speed washing effect generated by turbulent fluid flowing of the molten iron is sufficiently utilized, the molten iron is pushed backwards before being solidified, and the molten iron enters a forced cooling area of a water-cooled iron sleeve of the crystallizer and then is crystallized and solidified; and the surface of the cast iron proximate matter produced through the crystallizer is smooth in surface, the phenomenon of scar skin discharging is prevented from appearing, the structure is compact and uniform, hardness distribution is uniform, the mechanical property is improved to a certain degree, the cutting machining performance is good, the machining allowance is small, and the production cost is reduced.

The invention provides an ointment for promoting skin tissue regeneration. The ointment is prepared by mixing 2 ml of platelet rich plasma (the blood platelet concentration is 0.9-1.4*1015 / L), 0.01-0.15 mg of thrombin, 2-5 g of royal jelly, 0.03-0.12 mg of glutathione, 0.001-3 mg of vitamins, 5-25 mg of collagen peptide, 0.01-7.5 mg of nucleotide, 0. 03-0.5 mg of calcium chloride, 0.1-0.3 mg of chitosan, 2-5 mg of gelatin, 3-10 mg of glycerin, 0.1-2 mg of coenzyme, 0.01-0.4 mg of potassium chloride, 0.04-0.6 mg of magnesium sulfate, 0.03-0.5 mg of zinc oxide and 10-50 ml of distilled water. The ointment for promoting skin tissue regeneration can promote regeneration of depression scar skin tissue of the human body, is suitable for adjuvant treatment of depression scars and especially has the remarkable treating effect on depression scar wounds having the depth (5-15mm), meanwhile a treatment period can be shortened, and the treating period can be shortened to 25 days for depression scars having the depth of 5mm or below.