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Hydrogel scar patch for softening and fading scars

A scar patch and hydrogel technology, applied in ointment delivery, medical science, emulsion delivery, etc., can solve problems such as limited hydration, weak hydration, and limited water evaporation

Inactive Publication Date: 2013-05-08
HANGZHOU JUJIU SCI & BIOTECHNOLOGY CO +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, the above-mentioned silicone gel scar stickers have the following problems: 1. Weak hydration: First, this type of product does not contain moisture, and its hydration is blocked by silicone gel products through skin moisture evaporation, and the moisture is passive. Retained in the scarred skin, the hydration effect is limited; secondly, due to some serious injuries, such as third-degree burns, skin sweat glands, etc., the water evaporation is limited, and the hydration effect is greatly weakened; 2. Difficult to combine drugs: silicone gel It is difficult to combine in the scar patch, and it contains other ingredients that can inhibit scars, and the combination of drugs can improve the curative effect
Although the silicone gel membrane has a certain ability to pass through water vapor, the molecular weight of the drug or other effective ingredients for scars is usually dozens or hundreds of times that of the water molecule, so the permeability of the silicone gel to the membrane drug is even Yes, but very limited, therefore, silicone gel film is not an ideal carrier for transdermal absorption

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0009] Gel ointment is used as a drug delivery platform for another purpose: to treat scars; it has a good therapeutic effect on scars, can soften and dilute the scar tissue, and can flatten the scar. Its principle is based on the hydrophilic matrix of gel ointment, which has the following characteristics: 1. The hydrophilic gel matrix has a high water content, up to 70% or more, which can actively hydrate the scarred skin with a high degree of hydration, which is more beneficial The softening and flattening of the scar; 2. The hydrophilic gel matrix produces mechanical pressure on the skin surface, which can exert mechanical pressure on the scar body.

[0010] Experimental case analysis:

[0011] There are 17 cases in this group, including 6 males and 9 females, aged 10-65 years old, and the course of disease is from 1 month to 4 years. There were 8 cases of scar hyperplasia after burn, 7 cases of incision scar hyperplasia after operation, and 2 cases of keloid scar. In 6 cases,...

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PUM

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Abstract

The invention relates to a hydrogel scar patch for softening and fading scars. The invention is characterized in that: besides serving as a drug delivery platform, a gel plaster also can treat scars; it has good therapeutic effects on scars, can soften and fade scar tissues, and can flatten scars. The principle of the hydrogel scar patch is based on a gel plaster's hydrophilic matrix, which has the characteristics that: 1. the hydrophilic gel matrix has a high moisture content up to over 70%, can actively hydrate scar skin, and the hydration degree is high, thus being more conducive to softening and flattening of scars; and 2. the hydrophilic gel matrix generates mechanical compression on skin surfaces, thus exerting a mechanical pressure on scar bodies.

Description

technical field [0001] The present invention relates to a kind of hydrogel scar plaster with hydrogel as the main component, which is applied to the treatment of various scars. , Analgesic effect. Background technique [0002] Scars are the inevitable result of healing of various wounds, but if the healing is insufficient or excessive, scars will be formed, and if the scars continue to proliferate, hypertrophic scars can occur. According to the degree of damage caused by various injury factors and the physique of the injured, the following types of scars can be caused: superficial scars, atrophic scars, sunken scars, hypertrophic scars, keloids, especially for people with scar constitution, scars Especially obvious. Scars will bring great inconvenience to patients, such as hypertrophic scars caused by burns, which can cause local itching, pain, and even dysfunction, which seriously troubles patients. The prevention and treatment of scars has always been a difficult proble...

Claims

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Application Information

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IPC IPC(8): A61L15/42A61K9/06A61P17/02
Inventor 舒朝锋俞瑞珺
Owner HANGZHOU JUJIU SCI & BIOTECHNOLOGY CO
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