Electrophoretic display

Abstract

The present invention is directed to a transdermal delivery system for delivering a medicinal or cosmetic agent through the skin of a subject, which delivery system comprises (a) one or more display cells comprising partition walls and top-openings; (b) a liquid composition filled in the display cells wherein said liquid composition comprises the medicinal or cosmetic agent; and (c) a sealing layer to enclose the liquid composition within the microcups wherein said sealing layer is hardened in situ.

Description

[0001]This application is a continuation-in-part of U.S. application Ser. No. 13 / 426,464, filed Mar. 21, 2012; which is a continuation-in-part of U.S. application Ser. No. 11 / 774,773, filed Jul. 9, 2007, abandoned; which claims the benefit of U.S. Provisional Application No. 60 / 831,779, filed Jul. 18, 2006. The above-identified applications are incorporated herein by reference in their entirety.BACKGROUND OF THE INVENTION[0002]Various structures with peripheral plates or walls containing a liquid component were previously known. For example, a liquid component may be filled between two parallel or near-parallel surfaces and, in such a case, the liquid component is present in a continuous form. The two plates may be edge sealed first with fill holes for subsequent filling of the liquid component. Alternatively, the liquid component may be dropped on one of the two plates (before or after application of the edge sealing adhesive), followed by placing a second plate on top of the first...

AI Technical Summary

Benefits of technology

The film structure described in this patent allows for the production of microcups filled with liquid compositions that can be top-sealed. The microcups are of predetermined size and are used as built-in spacers to keep the substrates apart. This improves the mechanical properties and structural integrity of the film structure. Additionally, the use of the film structure eliminates the need for an edge seal adhesive and allows for a flexible manufacturing process that produces a continuous output in a large sheet format that can be cut into any desired sizes.

Problems solved by technology

However, such a continuous liquid phase structure suffers certain disadvantages.

For example, it lacks structure integrity and depth control, especially when the plates are flexible substrates.

In addition, this type of structure is not format flexible for production and, if hard surface plates are involved, batch manufacturing is required which results in low production efficiency.

It could be challenging to control the size of the microcapsules to be within a desired range.

In addition, the capsule wall usually does not provide good mechanical support for structural integrity, especially with flexible substrates.

Material selection is another issue with the microencapsulation technique.

In many cases, extra chemical(s) are necessary to stabilize the dispersed phase; the extra chemical(s), however, could be detrimental to the final product.

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