189 results about "Instrumental chemistry" patented technology

Systems and methods are described for laser ablation of an analyte from a specimen and capturing of the analyte in a dispensed solvent to form a testing solution. A solvent dispensing and extraction system can form a liquid microjunction with the specimen. The solvent dispensing and extraction system can include a surface sampling probe. The laser beam can be directed through the surface sampling probe. The surface sampling probe can also serve as an atomic force microscopy probe. The surface sampling probe can form a seal with the specimen. The testing solution including the analyte can then be analyzed using an analytical instrument or undergo further processing.

An analytical instrument stores and / or reads information related to a sample in a contactless memory, such as a passive or active radio-frequency identification (RF-ID) tag. The information may include information about: composition of the sample, one or more analytical instruments that were used to analyze the sample, operator(s) who used the instrument(s) to analyze the sample, user-entered data about the sample (such as an origin of the sample) or a combination thereof or the like. The memory may be attached to the sample or to a container, in which the sample is stored or transported. One or more copies of such a memory may be loosely stored with the sample, such as with soil in a plastic bag or a rail car. When the memory is attached to, or stored with, the sample, the sample becomes essentially self-documenting. Information about the sample, such as its composition or origin, may be read by a contactless memory reader, such as an RF-ID reader.

The invention relates to a method for measuring tobacco-specific nitrosamines (TSNAs for short) by using a super efficient liquid chromatogram-tandem mass spectrum combined method, and belongs to a method for detecting TSNAs. The method comprises the following steps of: adding internal standard-containing aqueous solution of ammonium acetate into a filter sheet after trapping smoke and cigarette filters smoked completely under standard conditions or tobacco shreds, performing ultrasonic extraction, transferring 1 to 2mL of extract into a small solid-phase extraction column taking N-vinyl pyrrolidone-benzene sulfonic acid copolymer as filler, flushing the small column by using aqueous solution of methanoic acid and methanol, finally eluting the small column by using solution of aqueous ammonia and methanol solution, analyzing the eluant by using an ultra performance liquid chromatography-mass spectrometer / mass spectrometer (UPLC-MS / MS), and quantifying according to the area ratio of a component peak to an isotope internal standard peak. The detecting method can be used for detecting the TSNAs in cured and hybrid cigarette mainstream smoke, cigarette side-stream smoke, filter tip intercepting smoke and tobacco shreds, and has the advantages of simple pretreatment, accurate quantification, high instrument analysis speed, low detection limit, high sample treatment flux and the like.

The invention discloses a method for measuring glycerinum and 1,2-propylene glycol in cigarettes, electronic cigarettes and low-temperature cigarettes. The method comprises cigarette suction, smoke capturing, sample extraction and instrumental analysis and specifically comprises the steps: (1) sucking the cigarettes, the electronic cigarettes and the low-temperature cigarettes through a range hood; (2) capturing components to be measured in mainstream smoke through a Cambridge filtering disk or an absorption bottle; (3) adding a solvent into the Cambridge filtering disk with the components to be measured for extraction; (4) filtering an extracting solution or an absorption solution in the absorption bottle for analysis and determination through an instrument. The method is high in reproducibility and high in analysis sensitivity and can be used for accurately and quantitatively analyzing the glycerinum and the 1,2-propylene glycol in the cigarettes, the electronic cigarettes and the low-temperature cigarettes. The method is easy to operate, and a measurement result is accurate; therefore, the industrial standard for evaluation and monitoring of the quality of a cigarette product is further perfected.

The invention discloses a high-throughput detection method for 99 residual veterinary drugs in animal-derived food. The detection method is characterized by comprising the following concrete steps: (1) carrying out extraction and purification on 99 residual veterinary drugs having substantially different physicochemical properties and belonging to eight kinds of common veterinary drugs through one-step pretreatment based on carrier-assisted liquid-liquid extraction technology; (2) preparation of a mixed standard solution and a matrix standard curve; and (3) determining the concentrations of 99 residual veterinary drugs in a to-be-detected solution by using ultrahigh performance liquid chromatography-triple quadrupole tandem mass spectrometry. According to the invention, the pretreatment and instrumental analysis process of the method is directed at compounds with different physicochemical properties, so the method has the advantages of good compatibility, high detection efficiency, good operability and low detection cost, and the detection limit of the method can meet requirements of all the test objects.

A fabric phase sorptive extractor (FPSE) is a sampling device where a flexible fabric is coated with at least one sol-gel derived film that includes at least two of a metal oxide portion, a siloxy portion, and an organic portion, where the gel has at least some amorphous portions. The FPSE is flexible such that it can be used in an extended form or draped over a solid surface to contact a gaseous, liquid, or solid environment and can be manipulated for placement in a container where the absorbed analyte can be removed from the FPSE for instrumental analysis. The FPSE can have specific functionalities that bind to specific analytes or can provide a general sorbent medium for extraction of a wide range of analytes, such that the sampling device can be employed for sampling analytes with biological, environmental, food, pharmaceutical, bio-analytical, clinical, forensic, toxicological, national security, public health, and / or safety implications.

The invention relates to a solid phase extract sampling bottle and heat analysis device in the field of sample measuring technology. It is a liquid-solid extraction and gas-solid absorption technology, which is used to pre-treat gas sample, liquid sample and isotropy sample and to extract and collect the objecting component, especially in color analysis and instrumental analysis. The solid phase extract sampling bottle and heat analysis device comprises an extract sampling bottle which is like a cylinder with one open end and one sealed end as bottom, and a casing and one layer extracting fixed phase on the middle part of the cylinder's inner wall, a heat analysis device and an extract sampling bottle cleaning device.

The invention belongs to the field of biological detection, and particularly relates to a color-fluorescence dual-function immunochromatography test strip and a preparation method thereof. The test strip comprises a base plate (1). A sample addition pad (2), a marker combination pad (3), a detection pad (4) and a water absorption pad (5) are sequentially arranged on one face of the base plate (1), wherein the detection pad (4) is provided with a detection line T (41) and a quality control line C (42), and the water absorption pad (5) provides power for a capillary tube siphoning, the adjacent pads are sequentially connected in an overlapped mode, and a color-fluorescence dual-function microsphere marker probe coats the marker combination pad (3). According to the color-fluorescence dual-function immunochromatography test strip and the preparation method thereof, negative and positive attribute preliminary qualitative judgment can be performed on the detection result through naked eyes, the detection result can also be analyzed through an instrument, and accurate detection data are obtained.

The invention relates to an elemental analyzer, and in particular relates to a laser-induced breakdown spectroscopy (LIBS) elemental analyzer. An accurate target point positioning laser-induced breakdown spectroscopy elemental analyzer is mainly characterized by comprising a pulse laser, wherein a laser beam is conducted onto an analysis sample inside a sample room through a laser transmission system; an accurate target point positioning system is arranged on the sample room; a target sample emission spectrum is connected with a spectrograph through a transmission optical fiber of the accurate target point positioning system. The elemental analyzer has the advantages that the whole suit of LIBS analyzer consists of a laser system, a light guide system, a positioning system and the sample room which are independent, so that the elemental analyzer can be taken as one piece of equipment and also can be used by conveniently replacing laser sources with different parameters, or an in-situ sample can be directly analyzed without using the sample room; the application range of the analyzer is enlarged, and the practicability and the commercialization of an instrument are promoted. The accurate target point positioning system can realize the micron dimension positioning of three-dimensional space and the automatic correction of target points, so that the accuracy of measurement and analysis results of the analysis instrument is improved, and the sensibility of analytical elements of the instrument is promoted.

Methods and apparatus for analyzing a test sample using complementary techniques, such as x-ray fluorescence (XRF) and optical emission spectroscopy (OES), are disclosed for registering two or more test instruments, in relation to the test sample, such that each of the instruments analyzes substantially the same region as is analyzed by the other instrument(s), and for communicating analytical results between or among the instruments, or between the instruments and another component, to enable one or more of the instruments, or the other component, to combine the results and, thereby, more completely and accurately determine the composition of the test sample. Such registration and communication enables, for example, separate XRF and OES instruments to collectively determine the composition of the test sample, including the absolute amounts of light and heavy elements in the test material.

Systems and methods are described for laser ablation of an analyte from a specimen and capturing of the analyte in a dispensed solvent to form a testing solution. A solvent dispensing and extraction system can form a liquid microjunction with the specimen. The solvent dispensing and extraction system can include a surface sampling probe. The laser beam can be directed through the surface sampling probe. The surface sampling probe can also serve as an atomic force microscopy probe. The surface sampling probe can form a seal with the specimen. The testing solution including the analyte can then be analyzed using an analytical instrument or undergo further processing.

A stress monitoring device of elasto-magneto-electric (EME) effect type, for monitoring stress of a structural component of ferromagnetic materials, includes a magnetic field generating unit, a magneto-electric (ME) sensing unit, a support skeleton, and a signal controlling and conditioning instrument. Under the control of the signal controlling and conditioning instrument, the magnetic field generating unit generates a magnetic field for magnetizing the structural component. The ME sensing unit outputs an electrical signal VME characterizing the magnetic field without a need of external power supply. This electrical signal VME is analyzed and processed by the signal controlling and conditioning instrument to output a magnetic characteristic value Vst corresponding to the changes of the external forces that are exerted on the component. This stress monitoring device realizes on-line, real-time, and nondestructive monitoring, as well as off-line nondestructive monitoring.

A composition, method and device for the preparation of biological samples for subsequent instrumental analyses, such as GC, GC-MS, LC and LC-MS analysis, using a solid phase extraction (SPE) process is described. Through SPE process alone or an integrated combination of protein precipitation, filtration, and SPE using a hydrophobic zirconia-coated chromatographic media, interfering compounds, such as proteins, glycerides and phosphate-containing compounds, are eliminated from the biological, food, environmental and biotechnology samples, affording an enhanced analyte response during the instrumental analysis.

The invention provides an artificial intelligence-based food flavor sensory evaluation system and an establishment method thereof. The food flavor sensory evaluation system comprises a component sensory detection system, a computer intelligent analysis system and a food flavor database, wherein the component sensory detection system consists of a GC-MS and a GC-O; the GC-MS is used for obtaining flavor feature original data of foods; the GC-O is used for obtaining artificial sensory evaluation data of food flavors; the computer intelligent analysis system is used for performing preprocessing and feature extraction on the flavor feature original data and the artificial sensory evaluation data, and performing dimension reduction and clustering analysis on the original data; and the food flavor database is established by performing fitting analysis on the flavor feature original data and the artificial sensory evaluation data obtained by the sensory detection system by a computer, combines the flavor original data and the artificial evaluation data, and comprises various data of mutual association of food volatile components. The instrument analysis is combined with the human body sensory evaluation, so that the one-sidedness and the defect of manual repetitive detection in an existing food flavor detection method are overcome, and an evaluation result is more comprehensive and reliable.

The invention is related to the instrumental analytical chemistry, further more to the stable isotope determination in food products. The present invention is referred to the alcohol thermal dehydration chamber, apparatus for “online” determination of isotopic composition of non-exchangeable hydrogen stable isotopes in ethanol samples, which comprises of: A) Alcohol thermal dehydration chamber, B) Detection device, which contains pyrolysis reactor and the Continuous Flow Isotope Spectrometer, and it is connected to the alcohol thermal dehydration chamber over C) System of valves, connectors and capillary tubes which are used for transfer of analyzed sample as for the purging of the alcohol thermal dehydration chamber; procedure for “online” determination of isotopic composition of non-exchangeable hydrogen stable isotopes in ethanol samples and procedure for “offline” preparation of ethene (ethylene) gas by means of alcohol thermal dehydration chamber and for the purpose of authenticity and geographical origin determination of wines, strong spirits, beer, fruit juices, honey and other food product which contain alcohol and / or fermentable sugars.

The invention relates to novel molecule detection signal amplification technique, which is characterized in that the molecule detection signal amplification technique is a biomolecule detection method with high sensitivity which is formed by streptavidin, an antigen, an antibody, polypeptide and the like which are marked by quantum dots through tyramine signal amplification and silver strengthening dyeing signal amplification. The detection method comprises the following steps: the biomolecule to be detected is combined with nucleic acid, the antibody, the antigen, the polypeptide and the like which are fixed on a solid phase material, the quantum dots are introduced to molecule to be detected through biomolecule specificity combination, silver strengthening dyeing is carried out on the quantum dots by using silver dyeing reagents, and signals are amplified. Obtained signals can be scanned through common optical scanners, analyzed through common imaging instruments or observed through naked eyes. The detection method achieves high sensitivity detection of the biomolecule on one hand, and reduces application cost of biomolecule detection on the other hand.

The invention discloses an infrared spectroscopic analysis method of the integral quality characteristic of mainstream smoke of cigarette. The analysis of the integral quality characteristic of mainstream smoke of a cigarette sample is completed through smoke collection, power-on and pretreatment of a vacuum infrared spectrometer, background subtraction, spectrum acquisition and data analysis. The method is suitable for the analysis and detection of the integral quality characteristic of the cigarette smoke, can directly acquire the integral spectral information of the mainstream smoke without individually trapping a granule phase part by a Cambridge filter, enhances the analysis sensitivity of the above device through the background subtraction and data preprocessing, and allows the main component score of a sample to be conveniently calculated through combining a metrological calculating technology, and the score characterizes the integral quality characteristic of the mainstream smoke of the sample. The score can be widely applied to the classification, the true and counterfeit cigarette identification and the homogenization evaluation of different samples. The whole evaluation process is fast and accurate, and is highly sensitive, and the method provides effective technical support for the quality improvement and the synergism of cigarette products and the development of new products.

The invention discloses a method for testing thermal conductivity by utilizing a differential scanning calorimeter, and the method comprises the following steps of: selecting one or a plurality of standard samples, putting samples under test between the standard samples and a crucible of the differential scanning calorimeter for testing, and comparing the measured results when putting the samples under test on the crucible with the measured results without putting the samples under test on the crucible to obtain the thermal conductivity of material. The method in the invention has the advantages of easy operation, low cost and accurate results, and belongs to the instrumental analysis field.

The invention provides a method for synchronously analyzing combustion residues of hydrocarbons and sulfides in a fire on-site combustion improver and solves the problem that serious influence of various fire on-site hydrocarbon analogues on an expert conclusion of the combustion improver. The method comprises the following steps of: extracting fire on-site combustion residue material to be tested, performing solid-phase microextraction, analyzing by a gas chromatograph-mass spectrometer, and judging an analysis result. The fire on-site combustion improver is identified; a detector is analyzed by fully using special sulfide markers retained in a petroleum product and adopting a special sulfide instrument, namely a pulse-type flame luminosity detector method is used for identification and analysis and combined with a gas chromatography (GC) / mass spectrometry (MS) method for analyzing hydrocarbos and aromatic-hydrocarbons, so that a gas chromatography-mass spectrometry-pulse type flame luminosity detector synchronous analysis method is constructed; therefore, the type of the combustion improver is easy to identify, the reproducibility is high and the data is stable.

The invention discloses a novel passive sampling device and related technology for monitoring anionic polar organic pollutants in water by using an anion exchange resin as a receiving phase. The anion exchange resin is placed between two layers of polyether sulfone membranes, which are fixed by cyclic organic glass flanges and silicone pads. The device can be suspended in the water to carry out passive collection on anionic polar organic pollutants dissolved in the water. After the passive sampling, the sampler is cleaned and treated with freeze drying; then the resin receiving phase is moved out; and the sample is treated with fractional extraction by alkaliferous methanol; and the extracting solution is concentrated and analyzed by instrument. The simulation results show that the sampling device can effectively acquire anionic polar organic pollutants in the aqueous solution. Taking perfluorobutyric acid and perfluorohexanesulfonic acid for example, concentrations of the two substances increase linearly with time in the receiving phase of the sampler in certain period, and concentration in the receiving phase is higher than that of water environment by 3-4 orders of magnitude.

The invention discloses a pretreatment method for strong-polarity pesticide residue detection. The pretreatment method comprises the steps of extracting strong-polarity pesticides from a sample through a methanol aqueous solution, purifying an extracting solution through a dispersive solid-phase extraction agent, and filtering the extracting solution for instrument analysis. The pretreatment method disclosed by the invention is a complementation and an improvement on the existing QuEChERS method, so that the shortcoming that the conventional internationally accepted QuEChERS method cannot be used for detecting the strong-polarity pesticides is overcome. The pretreatment method is easy to operate and high in reproducibility; the recycling rate of a strong-polarity compound is effectively guaranteed; meanwhile, impurities in the sample extracting solution are effectively removed during purification, so that pollution to a detection instrument is relieved, and the detection sensitivity is greatly improved.

The invention discloses a system for full-automated and online detection of perfluoro and polyfluoro compounds in serum. The system comprises a purification column, an analyzing column, a dual ternary liquid phase chromatograph, and a triple quadrupole detector, wherein an automatic sampler of the dual ternary liquid phase chromatograph is used for directly absorbing serum samples to be loaded forwards towards the purification column, and the analyzing column is flushed; after the serum samples are loaded, the purification column is back flushed for eluting target compounds, and the samples are fed into the analyzing column; after the serum sample are eluted, the line connection returns to the initial stage, and a left pump is used for regenerating the purification column; a right pump is used for introducing the samples into the triple quadrupole detector, so that detection of perfluoro compounds in the serum is realized. The system does not need a complex artificial preprocessing process, and the problems that the analyzing method of a conventional instrument is time-consuming and labor-consuming in the preprocessing course and the samples run off seriously are solved.

The invention discloses a testing method of volatile organic compounds in water. The testing method comprises the following steps of: separating volatile organic compound compounds in a to-be-tested water sample by means of a gaschromatograph of a gas chromatography mass spectrometry according to a standard gaschromatogram of a pre-prepared mixed standard solution; and testing the contents of the components of the separated volatile organic compound compounds in the to-be-tested water sample by means of the mass spectrometer of the gas chromatography mass spectrometry. According to the testing method of volatile organic compounds in water disclosed by the invention, except a sample pre-treatment process which needs to be manually intervened, other processes are finished by the instrument, so that the instrument is faster to analyze, small in error and high in accuracy. The volatile organic compound compounds such as halohydrocarbon, benzene series and chlorobenzene can be tested at the same time by instrument analysis at one time, so that the testing efficiency is effectively increased, and the labor cost is lowered.

The invention discloses an instrument analysis method for rapidly determining content of an occluded foreign substance in a material. The cleanliness of the material can be evaluated by accurate determination of the content of the occluded foreign substance in the material. The method comprises the following analysis processes: putting a sample into a sample box and placing into a sample chamber (3) charged by an inert protective gas; carrying out surface scanning analysis on the sample under the optimal instrument parameter condition; eliminating an abnormal value of all collected signal in a loop iteration manner according to Nalimov criterion; calculating the mean value and standard deviation of residual data; taking the standard deviation which is three times of the mean value as threshold strength for distinguishing the signal of the occluded foreign substance; building a mathematic model to carry out accurate and quantitative analysis on the content of the occluded foreign substance in the material on the basis of determining the threshold strength. Compared with the traditional wet process and single spark discharge atomic spectral analysis, the method has the advantages of being fast in analysis speed, high in sensitivity and the like, can analyze tiny, shaped and non-conductive material samples, and can be applied to rapid quantitative characterization of the occluded foreign substance content in the material.

The invention discloses a method for detecting short-chain chlorinated paraffins (SCCPs). The method comprises the following steps of: pretreating a sample by an ultrasonic extraction method; filtering extract liquor in a chromatograph bottle, and performing instrumental analysis; detecting the SCCPs by a gas chromatography-mass spectrometry technology; allowing the pretreated sample to enter a chromatographic column from a sample inlet of a gas chromatograph-mass spectrometer, and performing programmed heating; and allowing sample components which are separated by the chromatographic column to enter a mass spectrum detection part of the gas chromatograph-mass spectrometer through a port, and bombarding an ion source which is subjected to mass spectrum detection by using electrons. According to the method, an instrument is low in price and safe; an analysis method is accurate and quick and low in interference; and the SCCPs can be separated optimally.

The invention discloses a method for measuring the ammonia content of sidestream smoke of cigarettes. The method comprises the steps of preparation of a standard working solution, suction of the cigarettes, pretreatment of a sample, preparation of a solution to be measured, analysis with a chromatographic instrument, making of a standard working curve and calculation of a sample result. According to the method, the ammonia content of the sidestream smoke of the cigarettes is measured by adopting ion chromatography for the first time, and methods for capturing ammonia in the sidestream smoke of the cigarettes, namely specific capturing methods for a particulate matter (a filter disc) and gas-phase matters (a fishtail cover and an absorption bottle), are determined; the method is simple, quick, accurate, high in sensitivity and suitable for the measurement of ammonia content of the sidestream smoke of the cigarettes, and interference caused by impurity ions can be avoided.

The invention relates to a porcine circovirus 2 LAMP detection kit and detecting method. Based on the PCV2 gene sequence disclosed by GenBank, four PCV2 LAMP primers are designed in the sequence conservative region; the set PCV2 LAMPreaction system is adopted to conduct the LAMP reaction by taking the PCV2 HuB strain, PCV2LN strain virus DNA as a formwork. the LA-320 LAMP Tubidimeter is used for analyzing the added SYBRgreenI developer in the reaction process and after the reaction to judge the result, the result shows that the PCV2DNA has high-efficiency specificity amplification in LA-320 LAMP Tubidmeter at 63 DEG for 30 min, the SYBRgreenI developer is added to judge the result is consistent with the result displayed by the instrumental analysis. the sensitivity test proves that in the method, the 50ngPCV2 DNA formwork is diluted by 10, the efficient amplification still can be conducted, thus the method has high susceptibility. It shows that the method is special, simple and rapid, and is suitable for the PCV2 detecting work by the specificity test and the LAMP detecting of PVC2nucleic acid clinical sample.

The invention relates to a gas chromatography-surface acoustic wave rapid analysis and determination method for aldehyde and ketone materials, which utilizes gas chromatography and a surface acoustic wave sensor to rapidly analyze the concentration of the aldehyde and ketone materials and belongs to an instrument analysis method. The rapid analysis and determination method of the invention comprises the following steps: sampling the aldehyde and ketone materials in air; preprocessing samples, i.e. enabling the samples to be reacted with 2, 4-dinitrophenylhydrazine to prepare phenylhydrazone corresponding to the aldehyde and ketone materials; and adopting the gas chromatography and surface acoustic wave rapid analysis instrument to analyze the samples. The method of the invention has the advantages of short analysis time, analysis solution on the surface acoustic wave sensor of the volatile aldehyde and ketone materials, great analysis sensitivity enhancement, convenient operation and site analysis realization.

The invention discloses a method for quickly detecting heavy metal in water quality based on an ultra-infiltration microchip and belongs to the fields of material preparation and chemical examinationand analysis. The method comprises the following steps: firstly, reacting hydrophobic silica particles with fluorosilane in an ethanol solution to obtain superhydrophobic silica suspension; secondly,coating one side of a double-sided adhesive tape with the suspension to obtain superhydrophobic surface; finally, carrying out plasma etching in a designated area to obtain superhydrophilic microporesand an ultra-infiltration chip; pasting the ultra-infiltration chip on a specific substrate instrument by using the stickiness of the adhesive tape. By use of the ultra-infiltration chip, a color-producing reagent can be concentrated and enriched on the superhydrophilic micropores; the prepared ultra-infiltration chip can fix a detected solution on superhydrophilic sites by simple dipping operation, and colorimetric detection is realized by using a detection reagent on the hydrophilic sites. According to the method, the problems of high cost of a traditional apparatus analysis method and troublesome operation of a chemical analysis method are solved; the method is suitable for quick field detection of an aqueous solution.

The invention relates to a method for rapidly determining a retention rate of materials on a wire cloth. The invention provides a method for indirectly determining the retention rate by adopting instrumental analysis to test the concentration of upper wire feed liquid and white water liquid. The method comprises the following steps: 1. using a turbidimeter or a spectrophotometer to test the numerical values of the turbidity or light transmittance of the upper wire and the white water; 2. sequentially inputting the measured turbidity values or the light transmittance values into corresponding computation software to compute the upper wire paper material concentration and the white water concentration; and 3. substituting the concentration values into a formula SPR% =(c1-c2)*100% / c1 (in the formula, c1 is the upper wire feed liquid concentration and c2 is the white water liquid concentration) to compute the retention rate. The method shortens the test time, simplifies the operational procedures, reduces the test errors, can realize 'online detection' by combining with the computation software, and creates conditions for the 'real-time control' of the wet-end chemistry of papermaking.