460 results about "Autosampler" patented technology

Apparatus for carrying out patch clamp technique utilized in studying the effect of certain materials on ion transfer channels in biological tissue, and more particularly patch clamp apparatus utilizing an autosampler, such as those utilized with HPLC apparatus, to provide high throughput, is disclosed. The invention additionally includes novel microperfusion chamber assemblies capable of utilizing only small amounts of material to be tested and only small amounts of liquid carrier, thereby enabling many tests to be completed in a short period of time. The invention more broadly relates to a novel electrophysiology drug handling and application set up for screening of chemical substances while providing high throughput and requiring only low volume of solutions and samples to be tested. The invention also comprises several novel procedures for utilizing the apparatus of the invention.

An auto-injection system provides high throughput screening of fluidic samples. A sample injection valve has a first position which applies a reduced pressure to a sample sipper tube for aspirating a fluidic sample into the sample sipper tube, and a second position which delivers the fluidic sample to a sample supply loop. A column control valve has a first position which delivers the fluidic sample from the sample supply loop to a sample chromatography column, and a second position which reverses direction of fluid flow through the sample chromatography column to deliver the fluidic sample to a sample analyzer. A wash control valve has a first position which supplies a wash buffer solution to the sample chromatography column in a forward fluid flow direction, and a second position which supplies elution solvent to flush the sample supply loop.

The invention relates to an auto-injector (1) with a delay mechanism (36) for slowing down motion of a retraction sleeve (10) in axial direction of the auto-injector (1), the delay mechanism (36) comprising a circumferential outer wall (37) with a back collar (38) attached to a housing (2) of the auto-injector (1) and a circumferential inner wall (39) with a front collar (40) attached to the retraction sleeve (10) wherein a cavity is defined between the outer wall (37) and inner wall (39), the cavity sealed by the back collar (38) against the inner wall (39) and by the front collar (40) against the outer wall (37), the cavity filled with a viscous fluid, wherein at least one orifice is arranged in the delay mechanism (36) for allowing the viscous fluid to be pushed out as the volume of the cavity decreases due to axial motion of the component with respect to the housing. The retraction sleeve (10) is axially movably arranged in the housing (2) and serves for retracting the syringe (3) with the needle (4) into the covered position after delivering the medicament (M).

An autoinjector comprising an outer housing in which can be mounted a syringe for holding a volume of medicament, the syringe for holding medicament having a needle at one end thereof, a syringe holder for supporting the syringe in an axial position relative to the outer housing, and an intermediate housing at least part of which is located within said outer housing, characterised in that said intermediate housing is provided with a blocking means capable of abutting the syringe or the syringe holder so as to be capable of preventing forward axial movement of the syringe when a forward axial force is applied to said needle before actuation of the autoinjector to deliver an injection, but incapable of preventing forward axial movement of the syringe during actuation of the autoinjector to deliver an injection.

The present invention facilitates improvements in laser ablation of solid samples to be analyzed by an external inductively coupled plasma (ICP) emission spectrometer, ICP / mass-spectrometer (ICP-MS), or flowing afterglow (FAG) mass spectrometer (FAG-MS) for elemental analysis (ICP and ICP-MS) or molecular analysis (FAG-MS). A novel invention mirror-with-hole beam combiner eliminates chromatic aberration in the invention sample view and allows rad-hardening the laser ablation invention for use in a radiation hot cell for analysis of high activity nuclear waste. Many other novel invention rad-hardening attributes facilitate a comprehensive rad-hardened laser ablation system (the world's first). In other embodiments, invention novelties include unusually large homogeneous focused laser spot diameters, unusually long laser objective lens focal length, wide range operationally variable laser path length with built-in re-alignment, operationally variable demagnification ratio and diameter of the focused laser spot, the use of significantly higher powered SMR lasers in a large spot diameter to facilitate high sensitivity bulk analysis of solid samples, a demountable and gravitationally self-sealing stack assembly laser ablation cell, and the world's first auto-samplers (mechanized sample changers) for analytical laser ablation.

The invention discloses a multifunctional gas-chromatograph automatic sample injector comprising a rotary tower base, one side of the rotary tower base is provided with a sample disk assembly, a rotary tower is arranged on the rotary tower base, and an injector assembly is arranged on the rotary tower and comprises an injector and a needle core assembled with the injector; the needle core is arranged on a needle core fixing block driven by a vertically arranged synchronous belt and a synchronous belt of the needle core fixing block, the synchronous belt of the needle core fixing block and a sample disk are respectively driven by a stepping motor with a feedback encoder connected with a central processor, and the central processor is also connected with a human-computer interface. The multifunctional gas-chromatograph automatic sample injector has the advantages of convenient installation and use, strong university, 24-hour uninterrupted work when unattended, high sampling volume and repeatability precision, high degree of automation, manpower saving, alleviation of labor intensity of workers, enhancement of working efficiency and improvement on the accuracy of the sample analysis result of a gas chromatograph.