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49 results about "Guaiacol Glyceryl Ether" patented technology

Solid base catalyst, preparation of solid base catalyst as well as application of solid base catalyst to preparation of guaifenesin

The invention discloses a composite solid base catalyst which is mainly prepared from the following components in parts by mass: 100 parts of gamma-Al2O3 as a carrier, 0.5-5 parts of a binding agent as a loaded component, 1-25 parts of a magnesium-containing compound, 1-25 parts of a calcium-containing compound, 0.5-5 parts of polyacrylamide and 0.1-2 parts of inorganic base, wherein the binding agent is selected from one of glycerol, starch, methylcellulose, polypropylene glycol, alumina sol and sodium silicate; the magnesium-containing compound is selected from one of MgO, Mg(OH)2, Mg(CO3)2, Mg(OAc)2 and MgCl2; the calcium-containing compound is selected from one of CaO, Ca(OH)2, Ca(CO3)2 and CaCl2; the inorganic base is selected from one of NaOH, KOH, Na2CO3 and K2CO3. The catalyst is used for preparing guaifenesin, is simple and convenient to operate, environmentally friendly, low in energy consumption and high in yield.
Owner:ZHEJIANG HAIZHOU PHARMA CO LTD

Oral solid preparation containing ambroxol hydrochloride and guaifenesin active components

The present invention discloses an oral solid preparation containing ambroxal hydrochloride and guaifenesin active components. It is made up by using ambroxol hydrochloride and guaifenesin as active components and auxiliary material according to a certain ratio through a certain preparation process. Said oral solid preparation can be used for mainly curing the diseases of chronic bronchitis and periodic lower respiratory tract infection.
Owner:天津康鸿医药科技发展有限公司

Compound dextromethorphan hydrobromide syrup and preparation method for same

The invention provides a compound dextromethorphan hydrobromide syrup and a preparation method for the same. The compound dextromethorphan hydrobromide syrup is used for eliminating phlegm in cough, and comprises dextromethorphan hydrobromide, guaifenesin and a bacillus natto extract. The syrup improves the safety of medication and is especially suitable for children, reduces bitter taste and the consumption of a flavouring agent, improves the stability, especially the colour of solution and the stability of the colour, and improves the curative effect on the cough caused by cold and bronchitis simultaneously.
Owner:湖北凤凰白云山药业有限公司 +1

Improvement method of compound glycyrrhiza oral solution production technology

The invention discloses an improvement method of a compound glycyrrhiza oral solution production technology. The method comprises the steps of by taking 120ml of extractum glycyrrhizae liquidum, adding 120ml of glycerinum, evenly mixing, adding 500ml of water and diluting; then adding a proper amount of concentrated ammonia solution, and adjusting the pH value to be 8.00-9.00 to obtain an extractum glycyrrhizae liquidum solution; taking 5g of guaiacol glycerol ether, and adding a proper amount of hot water for dissolving to obtain guaiacol glycerol ether solution; adding the guaiacol glycerol ether solution into the extractum glycyrrhizae liquidum solution and stirring at the same time, adding 10g of sodium alginate and 5g of sodium carboxymethyl cellulose, and stirring for dissolving to obtain mixed solution; adding 180ml of compound camphor tineture into the mixed solution, evenly stirring, slowing adding right amount of concentrated ammonia solution, adjusting the pH value of the solution to be 8.00-8.50, and then adding a proper amount of water to form 1000ml of solution; evenly stirring, filtering and carrying sterilization to obtain the compound glycyrrhiza oral solution. The method solves the problems that the compound glycyrrhiza oral solution is easy to precipitate, easily goes bad, is unstable in product quality, etc.
Owner:GUANGXI NANNING BAIHUI PHARMA GRP

New synthetic method of guaiacol glycerin ether

The invention discloses a new synthetic method of guaiacol glycerin ether with a structure as shown in a formula (IV), isopropylidene glycerol-4-methanol with a structure as shown in formula (I) and guaiacol with a structure as shown in a formula (II) are taken as raw materials, Mitsunobu reaction occurs in organic solvent under the effect of triphenylphosphine and diisopropyl azodicarboxylate to generate intermediate product guaiacol isopropylidene glycerol ether with the structure as shown in formual (III); after full reaction, the obtained intermediate product crude product from separation witnesses hydrolysis reaction directly under acid conditions without purification; after separation and purification of the reaction liquid, the target product guaiacol glycerin with the structure as shown in (IV) ether is obtained. The synthetic method of the invention features application of clean raw material with low cost and easy availability, moderate reaction conditions, simple post treatment processes and adaptability to industrialized production.
Owner:ZHEJIANG UNIV OF TECH

Drug composition for relieving cough and reducing phlegm

The invention relates to a drug combination for relieving cough and reducing phlegm, which is composed of active constituents and a pharmaceutic adjuvant, wherein the active constituents comprise butamirate critrate, dextromethorphan hydrobromide and guaifenesin. The composition can be prepared into various kinds of oral preparations such as granules, troches, capsules, oral solution, syrup and the like and can be used for carrying out symptomatic treatment on related diseases with symptoms of cough, abundance of phlegm and the like.
Owner:BEIJING RUNDEKANG MEDICAL TECH CO LTD

Guaiamar dripping pill

The present invention discloses a kind of cough-relieving and phlegm-eliminating medicine composition, and is especially orally taken medicine composition dripping pill with guaiamar as active component. The guaiamar dripping pill has great medicine carrying amount, fast medicine releasing, fast acting, high bioavailability, less toxic side effect, convenient taking and low cost. The guaiamar dripping pill is prepared with guaiamar as active component, and through adding medicinal carrier as matrix, heating to obtain melt and / or emulsion and / or suspension of guaiamar and matrix, and dropping into condensating agent in dripping pill machine to form through shrinking.
Owner:北京博智绿洲医药科技有限公司

Talcum powder-guaifenesin water-based polyurethane anticorrosive paint for rattan crafts and preparation method thereof

The invention discloses talcum powder-guaifenesin water-based polyurethane anticorrosive paint for rattan crafts. The water-based polyurethane anticorrosive paint is prepared from the following raw materials in parts by weight: 0.5 to 1 part of nanometer talcum powder, 0.5 to 1 part of guaifenesin, 0.1 to 0.15 part of cetyl pyridinium chloride, 10 to 15 parts of nanocellulose suspension with 10 to 12% of solid content, 0.3 to 0.5 part of guar gum, 40 to 50 parts of water-based polyurethane resin, 0.5 to 1 part of octenyl succinic anhydride, 4 to 6 parts of absolute ethyl alcohol, 0.3 to 0.5 part of potassium sorbate, 0.5 to 1 part of kathon preservative, and 0.3 to 0.5 part of water-soluble lanolin. The water-based polyurethane anticorrosive paint has the advantages that the anti-bacterial and anticorrosive properties are good, the toughness is high, the binding property with rattan fiber is good, the easiness in cracking and falling is avoided, the paint film is fine and smooth, the color is uniform, the appearance quality is high, and the sanitation and decoration properties are good.
Owner:ANHUI MEIJING ARTS & CRAFTS CO LTD

Method for preparing methocarbamol

The invention discloses a method for preparing methocarbamol. The method comprises the steps that guaifenesin serves as a raw material, alkali and 4-dimethylaminopyridine serve as a catalyst, carbonicester serves as an esterification agent, and a compound shown in the formula (I) is obtained through an esterification reaction, the compound shown in the formula (I) reacts with ammonia water through an ammoniation reaction to obtain the methocarbamol shown in the formula (II), and the reaction equation of the methocarbamol is that the alkali is hydroxide or carbonate of the first main alkali metal group. Accordingly, guaifenesin serves as a raw material, the alkali and DMAP serves as the catalyst, the carbonic ester is catalyzed to be esterified and then ammonified and crystallized, and themethocarbamol is obtained. A nucleophilic reagent DMAP is used for catalysis, the carbonic ester can rapidly and highly selectively complete the reaction with hydroxide radical, and the high-yield guaifenesin ester is obtained; in addition, the dosage of the carbonic ester is small, safety and environmental protection are achieved, pollution is small, the economic benefit is high, operation is easy, and the method is suitable for industrial production.
Owner:ZHEJIANG HAIZHOU PHARMA CO LTD
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