Drug composition for relieving cough and reducing phlegm

A composition and drug technology, applied in the field of medicine, can solve the problems of weak disinfection and antiseptic effect, achieve remarkable effect and increase safety

Inactive Publication Date: 2011-05-04
BEIJING RUNDEKANG MEDICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, there are weak disinfection and antiseptic effects

Method used

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  • Drug composition for relieving cough and reducing phlegm
  • Drug composition for relieving cough and reducing phlegm

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0008] Embodiment 1: Compound butamidol granules:

[0009] prescription:

[0010]

[0011]

[0012] Process:

[0013] 1. Take dextromethorphan hydrobromide, butamidate citrate, and guaiacol glycerin and mix them evenly in equal increments.

[0014] 2. Take the above-mentioned mixed medicine, anhydrous sodium phosphate, magnesium hydroxide, sodium carboxymethylcellulose, xanthan gum, and sucrose in sequence and mix them uniformly in equal increments, add purified water to make a soft material, and granulate with an 18-mesh sieve. Dry at 50°C and sieve with 18 meshes.

[0015] 3. Add artificial cherry flavor and artificial banana flavor, mix evenly, divide into packages, 2g per bag.

Embodiment 2

[0016] Embodiment 2: compound recipe butamidate tablet

[0017] prescription:

[0018] Dextromethorphan Hydrobromide

5g

butamidate citrate

1.75g

Guaifenesin

15.0g

lactose

80.0g

microcrystalline cellulose

85.25g

Croscarmellose Sodium

10.0g

colloidal silica

2.0g

Magnesium stearate

1.0g

co-preparation

1000 pieces

[0019] Process:

[0020] 1. Take dextromethorphan hydrobromide, butamidate citrate, and guaiacol glycerin and mix them evenly in equal increments.

[0021] 2. Take the above-mentioned mixed medicine, lactose, microcrystalline cellulose, and croscarmellose sodium and mix them uniformly in equal increments, add purified water to make a soft material, granulate with a 18-mesh sieve, dry at 50°C, and dry for 24 Mesh sieve for whole grains.

[0022] 3. Add colloidal silicon dioxide and magnesium stearate, mix well, and press into tablets with a weight of 20...

Embodiment 3

[0023] Embodiment 3: compound butamidate capsules

[0024] prescription:

[0025] Dextromethorphan Hydrobromide

5g

butamidate citrate

1.75g

Guaifenesin

15.0g

lactose

80.0g

microcrystalline cellulose

85.25g

Croscarmellose Sodium

10.0g

colloidal silica

2.0g

Magnesium stearate

1.0g

co-preparation

1000 capsules

[0026] Process:

[0027] 1. Take dextromethorphan hydrobromide, butamidate citrate, and guaiacol glycerin and mix them evenly in equal increments.

[0028] 2. Take the above-mentioned mixed medicine, lactose, microcrystalline cellulose, and croscarmellose sodium and mix them uniformly in equal increments, add purified water to make a soft material, granulate with a 18-mesh sieve, dry at 50°C, and dry for 24 Mesh sieve for whole grains.

[0029] 3. Add colloidal silicon dioxide and magnesium stearate, mix well, fill, and each capsule weighs 200mg.

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PUM

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Abstract

The invention relates to a drug combination for relieving cough and reducing phlegm, which is composed of active constituents and a pharmaceutic adjuvant, wherein the active constituents comprise butamirate critrate, dextromethorphan hydrobromide and guaifenesin. The composition can be prepared into various kinds of oral preparations such as granules, troches, capsules, oral solution, syrup and the like and can be used for carrying out symptomatic treatment on related diseases with symptoms of cough, abundance of phlegm and the like.

Description

technical field [0001] The invention relates to a pharmaceutical composition for suppressing cough and reducing phlegm, belonging to the technical field of medicine. Background technique [0002] Butamidate is a central antitussive drug, and its antitussive effect is 5 times stronger than that of codeine. Can promote the secretion of bronchial mucus. It is suitable for the treatment of cough caused by upper respiratory tract infection. [0003] Dextromethorphan hydrobromide is a central antitussive drug that selectively inhibits the cough center, thus exerting an antitussive effect. The antitussive effect is quick onset, and the coughing process is significantly suppressed. It has no analgesic effect, and no tolerance or addiction has been found in long-term use. [0004] Guaifenesin as an expectorant for nausea http: / / www.a-hospital.com / %B6%F1%D0%C4.htmlhttp: / / www.a-hospital.com / %EC%EE %CC%B5%D2%A9.html. After oral administration, it can stimulate the gastric mucosa an...

Claims

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Application Information

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IPC IPC(8): A61K31/485A61K31/216A61K31/09A61P11/14A61P11/10
Inventor 李宝奇
Owner BEIJING RUNDEKANG MEDICAL TECH CO LTD
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