178 results about "Globin" patented technology

The present invention relates to an expression vector for animal cells. Specifically, the present invention relates to an expression vector, pMS vector, pSG vector and pMSG vector, including the human β-globin 5′ MAR complementary sequence or / and the transcription termination site of the gastrin gene. An expression system using an expression vector of the present invention can successfully produce recombinant proteins in various animals cells and recombinant protein having a unique structure and function.

An implantable preparation comprises a material which can be obtained from globin that has been modified, especially chemically, to be, at least partially, soluble at physiological pH. The material is biocompatible, and biodegradable in the organism. The material may be soluble at physiological pH, or insoluble at that pH. The preparation may be in the form of a solution, suspension, paste, gel, film, sponge, powder or granules, or a solid implant. The preparation can be used for the healing, protection or filling of external skin wounds, the filling of wrinkles and skin flaws, the filling of tissue, as a device for fixing prostheses or biomaterials, or as a device for preventing adhesion.

The present inventors concerns vectors carrying a truncated chimeric CMV-chicken β-actin (smCBA) promoter in which the hybrid chicken β-actin / rabbit β-globin intron is greatly shortened, and their use to deliver to an operatively linked polynucleotide to host cells in vitro or in vivo, resulting in expression of the polynucleotide in the host cells. In one embodiment, the vector carrying the smCBA promoter is administered to the eye. In another embodiment, the vector carrying the smCBA promoter is a self-complementary adeno-associated virus (AAV). The AAV vector may be of any serotype (e.g., type 1, type 2, type 3, type 4, type 5, type 6, type 7, type 8, type 9, type 10). In another embodiment, a self-complementary vector carrying the smCBA promoter is administered to the eye. Another aspect of the invention concerns host cells carrying a vector of the invention. Another aspect of the invention concerns pharmaceutical composition comprising the vectors or host cells of the invention, and a pharmaceutically acceptable carrier.

The present invention discloses methods, primer, probes, and kits for genotyping various mutations or disease-causing agent. In one embodiment, the present invention is applied to detecting the presence of multidrug-resistant Mycobacterium tuberculosis, HBV, beta-globin mutations, mutations related to thrombophilia, or the presence of sexually transmitted diseases in a subject.

A method for quantitative hemoglobin determination in undiluted, unhemolyzed whole blood comprises: acquiring a sample of unaltered whole blood into a capillary cuvette, presenting said cuvette to a set-up for an absorption measurement, delaying absorption measurement for a determined period of time, performing a first absorption measurement at a first wavelength in the range 490-520 nm directly on the sample in the cuvette, further conducting a second absorption measurement at a second wavelength different from the first wavelength and at which the absorption is substantially smaller than at the first wavelength, and processing results of the first and second absorption measurements to determine the concentration of hemo- globin in the sample. A system for implementing the method is also disclosed.

The invention provides an adult fish feed of larimichthys crocea. The adult fish feed is prepared from the following components according to mass parts of air dry matters: 21-24 parts of fish meal, 3-4 parts of hydrolyzed fish protein meal, 3-4 parts of atomized and dried globin powder, 3-4 parts of shrimp meal, 4-5 parts of shrimp shell meal, 2-3 parts of euphausiid shrimp meal, 7-8 parts of silkworm chrysalis meal, 6-8 parts of fermented soybean meal, 3-5 parts of fermented cotton seed protein, 1-4 parts of peanut meal, 2-3 parts of sesame meal, 2-3.5 parts of corn DDGS, 4-7 parts of corn protein powder, 9.5-11 parts of flour, 8.5-10 parts of cassava starch, 1.5-2.5 parts of fish oil, 1-2 parts of soybean oil, 1-2 parts of soybean phospholipid oil, 1.5-2 parts of calcium dihydrogenphoshate, 1 part of Chinese herbal medicine compound preparation and 2 parts of premix additive. The Chinese herbal medicine compound preparation is prepared from the following substances in parts by weight: 12 parts of lonicera japonica, 6 parts of tuber onion seeds, 10 parts of poria cocos, 4 parts of polygala tenuifolia willd, 4 parts of cuscuta chinensis, 4 parts of carthamus tinctorius L and 60 parts of rice hull powder. According to the adult fish feed, the immunity of the larimichthys crocea can be enhanced and the larimichthys crocea can be prevented from being infected with sarcoidosis; and the adult fish feed has a good treatment effect on the larimichthys crocea with the sarcoidosis, and the cultivation survive rate of the larimichthys crocea is improved.