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63 results about "Ethanol metabolism" patented technology

Ethanol, an alcohol found in nature and in alcoholic drinks, is metabolized through a complex catabolic metabolic pathway. In humans, several enzymes are involved in processing ethanol first into acetaldehyde and further into acetic acid and acetyl-CoA. Once acetyl-CoA is formed, it becomes a substrate for the citric acid cycle ultimately producing cellular energy and releasing water and carbon dioxide. Due to differences in enzyme presence and availability, human adults and fetuses process ethanol through different pathways. Gene variation in these enzymes can lead to variation in catalytic efficiency between individuals. The liver is the major organ that metabolizes ethanol due to its high concentration of these enzymes.

Composition with disintoxicating and liver-protecting effects and application thereof in food and health-care food

The invention relates to a composition with disintoxicating and liver-protecting effects, which comprises the following raw materials in percentage by mass: 0.15 to 5 percent of crucumin, 0.04 to 1.0 percent of zinc lactate, 10 to 50 percent of glutamine, 10 to 50 percent of alanine and 10 to 50 percent of xylooligosaccharide. It is proved that, by an animal experiment and a human tasting experiment, the composition increases the alcohol dehydrogenase and acetaldehyde dehydrogenase content of a body and rapidly decomposes alcohol, so that the composition has the effects of promoting alcohol metabolism in a liver and reducing the alcohol concentration and active oxygen concentration in a blood; and the composition increases an endurance capacity of a human body to the alcohol, reduces the discomforts such as headache, nausea, vomiting and the like due to the alcohol, and reduces the damages of the alcohol to the liver. The composition can be prepared into food and health-care food with the disintoxicating and liver-protecting effects, can be used as a disintoxicating product for preventing and improving excessive drinking, and can be used as an adjuvant therapy product for an alcoholic liver, a fatty liver due to the alcohol or non-alcohol and protecting the liver; and the composition has the advantages of safety, non-toxicity and a reliable curative effect.
Owner:SHANDONG MINGREN FURUIDA PHARMA

Compound prepared by probiotic-fermented traditional Chinese medicine (TCM) preparation as well as preparation method and application of compound

The invention discloses a compound prepared by probiotic-fermented traditional Chinese medicine (TCM) preparation as well as a preparation method and application of the compound. The compound takes a culture solution containing crude TCM drugs such as astragalus, semen hoveniae, flower of kudzuvine, radix paeoniae alba and ligusticum wallichii, and takes fermentation liquor fermented by probiotics, such as bifidobacterium bifidum, lactobacillus acidophilus and bacillus subtillis, as an effective ingredient. The compound disclosed by the invention can be used for promoting ethanol metabolism in the liver, lowering ethanol concentration in blood, enhancing the endurance capacity of a human body to alcohol, and alleviating discomforts of head and face redness, dizziness and the like caused by alcohol. Foods and healthcare foods prepared by the compound disclosed by the invention can be taken as safe and reliable anti-alcoholic products for preventing and alleviating excessive drinking.
Owner:UNIV OF JINAN

3-methylquinoxaline-2-carboxylic acid artificial antigen and antibody obtained by the 3-methylquinoxaline-2-carboxylic acid artificial antigen

The invention discloses a 3-methylquinoxaline-2-carboxylic acid artificial antigen and an antibody obtained by the 3-methylquinoxaline-2-carboxylic acid artificial antigen. The invention provides a compound shown in the formula (I). The compound shown in the formula (I) is prepared by structural modification of 3-methylquinoxaline-2-carboxylic acid, retains a feature structure of 3-methylquinoxaline-2-carboxylic acid as much as possible and has active groups which can couple with a carrier protein. The 3-methylquinoxaline-2-carboxylic acid artificial antigen provided by the invention is a conjugate prepared by coupling of the compound shown in the formula (I) and a carrier protein. The 3-methylquinoxaline-2-carboxylic acid artificial antigen is used for animal immunization so that high-specificity monoclonal and polyclonal antibodies are obtained. A preparation method of the high-specificity monoclonal and polyclonal antibodies is simple and practicable. The 3-methylquinoxaline-2-carboxylic acid artificial antigen can be used for detection of olaquindox metabolites. The antibodies obtained by the 3-methylquinoxaline-2-carboxylic acid artificial antigen can be used for detection of olaquindox metabolites.
Owner:CHINA AGRI UNIV

Traditional Chinese medicine with anti-inebriation function

The invention relates to a traditional Chinese medicine combination which is provided with the effect of alleviating alcoholism and is made by extracting and processing the raw materials of a jackfruit, kudzuvine root, kudzuvine flower, raisin tree seed, ebony and liquorice. The product of the invention is capable of reducing human body absorbing the ethanol, promoting the ethanol metabolism inside body and increasing the ethanol egesting, so as to reinforce human body resistance capability towards the ethanol and improve and remedy the uncomfortable symptoms caused by drinking wine, such as the headache, the light in the head, the nausea etc. and take effect of alleviating alcoholism.
Owner:INST OF TROPICAL BIOSCI & BIOTECH CHINESE ACADEMY OF TROPICAL AGRI SCI

Saccharomyces cerevisiae engineering strain as well as preparation method, application and fermentation culture method thereof

The invention relates to the technical field of bioengineering, and in particular relates to a saccharomyces cerevisiae engineering strain as well as a preparation method, application and a fermentation culture method thereof. The PDC1, PDC5, PDC6, ADH1 and ADH4 genes of the saccharomyces cerevisiae engineering strain are knocked out, and an LDH gene is inserted into the saccharomyces cerevisiae engineering strain. The saccharomyces cerevisiae engineering strain provided by the invention does not contain an ethanol metabolism main route, a lot of glucose can be used for fermentation so as to accumulate lactic acid, and the strain can grow quickly by using ethanol.
Owner:TIANJIN UNIV

Glycerol channel protein gene deleted brewing microzyme strain capable of reducing glycerol output and increasing ethanol output and construction method thereof

The present invention discloses one kind of Saccharomyces cerevisiae strain with glycerin passage protein gene deficiency and resulting in lowered glycerin generation and raised ethanol yield and its construction process. The construction process includes the following steps: 1. obtaining Saccharomyces cerevisiae monoploid and deleting of URA3 gene; 2. constructing PUC18-FPS1-ORF plasmid; 3. constructing PUC18-FUF plasmid; and 4. constructing KAM-21 strain. The present invention deletes glycerin passage protein FPS1 gene code embedded on cell membrane and loses the expression of FPS1 gene by means of gene engineering technology, so as to inhibit glycerin synthesizing way, convert from glycerin metabolism to ethanol metabolism, increase ethanol yield, and solve serial problems in ethanol production.
Owner:TIANJIN UNIV

Amygdalus persica/amygdalus davidiana resin polysaccharide embedded natural antioxidant composition and application thereof

The invention discloses an amygdalus persica / amygdalus davidiana resin polysaccharide embedded natural antioxidant composition and an application thereof. The composition can effectively prevent intoxication caused by single-time heavy-dosage wine drinking and relevant organism health risks after intoxication. The composition is prepared through the following steps of in an aqueous solution system, using amygdalus persica / amygdalus davidiana resin polysaccharide as a wall material, and performing micro nanocrystallization embedding on a natural antioxidant so as to obtain the composition. Preferably, in the composition, the mass concentration of the amygdalus persica / amygdalus davidiana resin polysaccharide is not greater than 5%g / mL, and the optimal mass concentration is 1%-2.5%g / mL. According to the amygdalus persica / amygdalus davidiana resin polysaccharide embedded natural antioxidant composition disclosed by the embodiment of the invention, the amygdalus persica / amygdalus davidianaresin polysaccharide forms a protective barrier resistant to digestive enzyme decomposition in gastrointestinal tracts, so that chemical damage of high-concentration ethanol to stomach and intestinemucosa can be avoided or reduced; and natural antioxidant molecules through micro nanocrystallization embedding of the amygdalus persica / amygdalus davidiana resin polysaccharide can restrain oxidativestress cascading damage caused by ethanol metabolism, the activity of alcohol dehydrogenase and acetaldehyde dehydrogenase in bodies can be activated and increased, and ethanol metabolism can be promoted.
Owner:JIANGHAN UNIVERSITY

Olaquindox metabolite immunochromatography test paper card and preparation method thereof

The invention discloses an olaquindox metabolite immunochromatography test paper card and a preparation method thereof and belongs to the technical field of veterinary drug residue immunochemistry fast detection. The test paper card comprises a plastic card shell and a test paper strip encapsulated in the plastic card shell. A sample adding hole and an observation window are formed in the plastic card shell. The bottom layer of the test paper strip is a support layer. A sample pad, a colloidal gold pad, a testing pad and a water absorption pad which are connected in a overlap manner are sequentially attached to the support layer from left to right. The test paper card is simple to operate, fast, accurate, high in flexibility, high in specificity, vivid and visualized in result display, and the like. In addition, the test paper card is capable of on-site monitoring and suitable for screening of a huge amount of samples.
Owner:HENAN INST OF SCI & TECH

Engineering rice with functions of alleviating hangover and protecting liver and preparation method of engineering rice

The invention relates to engineering rice with functions of alleviating hangover and protecting liver and a preparation method of the engineering rice. For people who drink for a long time or overdrink, the invention provides the engineering rice with functions of alleviating hangover and protecting liver and the reparation method of the engineering rice. The engineering rice comprises six raw materials of brown rice powder, soybean protein isolate, kudzuvine root extract, corn oligopeptide, purple sweet potato powder and hawthorn extract. The engineering rice is prepared by the following steps: premixing the raw materials; performing high-temperature high-pressure texturizing forming by using a double screw extruder; and drying, dedusting and packaging to obtain the engineering rice. Thecoarse cereal component of the engineering rice has the effects of balancing diet and guaranteeing nutrition ingestion of people who eat the engineering rice; and functional factors such as the corn oligopeptide, the kudzuvine root extract and the like have the functions of enhancing ethanol metabolism inside the bodies, reducing liver injury, alleviating hangover and protecting liver.
Owner:CHINA NAT RES INST OF FOOD & FERMENTATION IND CO LTD +3

Preparation method and applications of olaquindox metabolite hapten

The invention discloses olaquindox metabolite hapten, and corresponding artificial antigen and monoclonal antibody. In addition, the invention also discloses a preparation method and applications of the olaquindox metabolite hapten and corresponding artificial antigen and monoclonal antibody. The olaquindox metabolite antigen can be obtained by connecting the olaquindox metabolite hapten with a carrier protein. The olaquindox metabolite antigen can be applied to preparing olaquindox metabolite specific antibody. The preparation method is simple, convenient and feasible, and lower in cost, and the hapten yield is higher. The artificial olaquindox metabolite antigen can produce olaquindox metabolite-targeted specific antibody through immune animal, can be used for preparing an enzyme linked immunosorbent assay kit or a colloidal gold test paper card for detecting the residual olaquindox metabolite in food, and the olaquindox metabolite hapten has various advantages of being simple, fast, large in sample processing quantity, high in sensitivity, strong in specificity and the like.
Owner:BEIJING KWINBON BIOTECH

Detection method for metabolite residues of carbadox and olaquindox in animal tissues

The invention discloses a detection method for metabolite residues of carbadox and olaquindox in animal tissues. The detection method comprises the following steps: adding internal standard working fluid in a sample, extracting the sample by using a metaphosphoric acid-methanol solution, adding ethyl acetate in an extracting solution to be extracted, separating upper-layer ethyl acetate layer, carrying out rotary evaporation until being dried, carrying out constant-volume dissolution on the residues by using a methanol-formic acid solution, filtering through a 0.22<mu>m filter membrane, and performing qualitative and / or quantitative detection by using a liquid chromatograph-tandem mass spectrometer. The detection method for the metabolite residues of carbadox and olaquindox in the animal tissues disclosed by the invention is simple in sample treatment method and low in operation cost, the determination low limit of quinoxaline-2-carboxylic acid and 3-dimethyl quinoxaline-2-carboxylic acid is 1 mu g / kg, quinoxaline-2-carboxylic acid and 3-dimethyl quinoxaline-2-carboxylic acid are in line with a linear relationship in the range of 2 ng / mL to 200 ng / mL, the linear correlation coefficient r is more than 0.99 and the average recovery rate is ranged from 82.71% to 121.09%, and RSD is ranged from 4.07% to 9.51% (n is equal to 6), thereby indicating that the accuracy and sensitivity of the method meet detecting demands.
Owner:SHIJIAZHUANG UNIVERSITY

Corn peptide composition for alleviating hangover and protecting liver and preparation method thereof

InactiveCN109432386AIncrease ADH activityAccelerated elimination rateHydrolysed protein ingredientsDigestive systemSide effectLiver tissue
The invention provides a corn peptide composition for alleviating hangover and protecting liver and a preparation method thereof. The corn peptide composition comprises the following active components: corn peptide, radix puerariae, semen hoveniae and fructus lycii, and further comprises rhizoma curcumae longae. The corn peptide composition provided by the invention achieves excellent effects of alleviating hangover and protecting liver by combining the corn peptide, radix puerariae, semen hoveniae, fructus lycii and rhizoma curcumae longae at a specific ratio and playing a synergistic effect,has no toxicity and no harm, can improve ADH activity of liver tissues, promotes ethanol metabolism, increases an elimination rate of ethanol metabolites, reduces damage to tissues and cells, plays roles of alleviating hangover and promoting sobering, protects the liver, reduces dependence and use on drugs to reduce toxic and side effects of the drugs, has advantages of simple preparation methodand low production cost, and is suitable for mass consumption.
Owner:武汉森澜生物科技有限公司

Amino acid and plant compound composition for relieving alcoholism and protecting liver and application thereof in foods and health foods

The invention relates to a composition for relieving alcoholism and protecting liver. The composition is prepared from the following raw materials in parts by weight: 2-3 parts of L-cysteine, 3-6 parts of taurine, 8-12 parts of glycine, 10-20 parts of curcumin, 10-20 parts of silymarin and 30-60 parts of quercetin. An in-vitro alcohol dehydrogenase (ADH) activity test and an oxygen radical absorbance capacity (ORAC) test prove that the composition disclosed by the invention has the capacity of instantly and effectively improving the activity of alcohol dehydrogenase (ADH) and accelerating ethanol metabolism, and can be used for efficiently clearing free radicals, reducing oxidative damages caused by ethanol and simultaneously preventing adverse outcomes including drunkenness, dizziness, alcoholic liver injuries and the like caused by one-time heavy drinking and long-term drinking. The composition can be prepared into foods and health foods with functions of relieving alcoholism and protecting liver, and can be used as an auxiliary product and the like for instantly relieving alcoholism and protecting the liver for a long time.
Owner:北京中科邦尼国际科技有限责任公司

Sprouted rice ecological beer and production method thereof

The invention relates to sprouted rice ecological beer and a production method thereof. Raw materials of the beer comprise water, malt, flor products, lactic acid, temperature-resistance enzyme and food additives. The sprouted rice ecological beer is characterized in that the raw materials of the beer also comprise sprouted rice instead of ordinary rice or corn starch in traditional beer raw materials, and finished beer products are finally obtained through gelatinization, saccharification, boiling, fermentation and filtering. Because the raw materials comprise the sprouted rice, the ecological beer comprises rich nutrients which are rich in the sprouted rice, particularly, the contents of contained protein, fat, vitamin B1 and vitamin E in the beer are higher than the contents in the ordinary beer, IP-6 contained in the beer has high anti-oxidation capability and can help to treat renal calculus and to reduce cholesterol and blood fat, and in addition, the anti-cancer effect is realized; and upsilon-aminobutyric acid has the effects of improving the brain blood circulation, regulating the blood pressure, calming the nerves and the like, can also reach the functions of reducing the blood pressure, calming the nerves, improving the kidney and liver functions, improving the lipid metabolism, reducing the neutral fat, preventing the arteriosclerosis, reducing the ethanol content in blood and promoting the ethanol metabolism and has a good health care effect.
Owner:HUNAN ECOLOGICAL CONSTR TECH DEV

Engineered rice having alcoholism relief and liver protection function, and preparation method thereof

The present invention relates to a functional engineered rice having alcoholism relief and liver protection functions for those drinking alcohol over an extended period of time or drinking alcohol excessively, and preparation method thereof. The engineered rice comprises six starting materials: coarse rice powder, isolated soy protein, kudzu root extract, corn oligopeptide, purple sweet potato powder, and hawthorn extract, and is prepared by: premixing the starting materials; employing a double screw extruder to conduct texturized processing and forming under high temperature and high pressure; and then drying, dedusting and packaging. The coarse cereal components of the engineered rice have the effects of balancing the diet and ensuring nutrition ingestion for those consuming the rice; and the functional factors such as the corn oligopeptide, the kudzu root extract and the like have the functions of enhancing ethanol metabolism inside the body, reducing liver damage, relieving alcoholism and protecting the liver.
Owner:CHINA NAT RES INST OF FOOD & FERMENTATION IND CO LTD +1

Method for detecting contents of olaquindox metabolite and carbadox metabolite in animal muscle tissue and sample pretreatment method thereof

The invention discloses a method for detecting contents of olaquindox metabolite and carbadox metabolite in animal muscle tissue and a sample pretreatment method thereof. The sample pretreatment method for detecting the contents of the olaquindox metabolite and the carbadox metabolite in the animal muscle tissue includes the steps that to-be-detected animal muscle tissue samples are taken, hydrochloric acid solution is added for acidolysis, then ethyl acetate is added to extract the olaquindox metabolite and the carbadox metabolite, and mixed liquor is obtained; MgSO4 and Nacl are added to themixed liquor, the vortex and centrifugation are carried out, and supernatant is collected from the upper layer; the supernatant is concentrated and redissolved, then methanol saturation normal hexanesolution is added, the vortex and centrifugation are carried out, the lower solution is collected, the filtration is carried out, and to-be-detected solution is obtained. The invention further discloses the method for detecting the contents of the olaquindox metabolite and the carbadox metabolite by LC-MS after sample pretreatment. The method for detecting the contents of the olaquindox metabolite and the carbadox metabolite in the animal muscle tissue and the sample pretreatment method thereof has short time consumption, easy procedure, good repeatability and high result accuracy.
Owner:BEIJING ENTRY EXIT INSPECTION & QUARANTINE BUREAU INSPECTION & QUARANTINE TECH CENT

Functional beverage relieving drunk discomfort and preparation method

InactiveCN102813266ASatisfy the requirement of sweet-acid ratioReduce concentrationFood preparationSucroseVitamin C
The invention relates to a functional beverage relieving drunk discomfort and a preparation method. The beverage is composed of a plant extraction solution, a flavoring-electrolyte mixed solution, a functional material solution, and pure water. The plant extraction solution is obtained by extraction of Hovenia dulcis Thunb, radix puerariae, and other raw materials. The flavoring-electrolyte mixed solution is composed of a mixture of sucrose and glucose, citric acid, a sweetener and the like. The functional material solution is composed of vitamin B6, vitamin C, taurine, inositol, and curcumin, etc. The beverage provided in the invention can rapidly supplement lost water and sodium, potassium, calcium, magnesium as well as other electrolytes, reduce the blood alcohol concentration, supplement the body required energy, enhance the activity of ethanol metabolism related enzymes and protect the liver, thus reaching the purposes of relieving drunk discomfort and eliminating the hangover feeling. The functional beverage provided in the invention has abundant and easily available raw materials, and rigorous and mature process, thus being suitable for industrial production and promotion.
Owner:湖北乡野农业发展有限公司

Multifunctional health burdock tea paste and preparation method thereof

The invention discloses multifunctional health burdock tea paste. The multifunctional health burdock tea paste is prepared from burdock root, fructus arctii, green tea, mushroom and cordyceps militaris as raw materials through enzymolysis and extraction. The multifunctional health burdock tea paste has functions of burdock root, fructus arctii, green tea, mushroom and cordyceps militaris producing synergism and has abundant nutrition values and health care functions. The health care functions comprise human humoral immunity improvement, viral resistance and cancer resistance. The burdock, cordyceps militaris and mushroom extract can effectively prevent ethanol from entering blood, protect liver and accelerate an ethanol metabolism rate in vivo so that the multifunctional health burdock tea paste has effects of relieving the effect of alcohol and sobering up and is an ideal health drink.
Owner:王国泰 +2

Olaquindox metabolin antigen, antibody, enzyme-linked immunosorbent assay kit and detection method

The invention discloses an olaquindox metabolin antigen, an antibody, an enzyme-linked immunosorbent assay kit and a detection method. 4-(3-methyl-2-naphthalene carboxamide) butyrate is taken as an olaquindox metabolin hapten; the olaquindox metabolin antigen can be acquired after the hapten is coupled with carrier protein; the olaquindox metabolin antigen can be used for preparing an olaquindox metabolin specific antibody; the specific antibody can be used for preparing the enzyme-linked immunosorbent assay kit or colloidal gold test paper card used for detecting the residue of olaquindox metabolin in food. The invention also discloses the corresponding detection method of the kit. The method is simple, convenient and quick and is characterized by linear detection range within 0.2-16.2ng / mL, sensitivity of 0.54ng / mL, limit of detection of 0.32ng / mL, recovery rate within 80%-109.8%, low detection limit, high sensitivity, high specificity, high stability, low cost and suitability for mass sample detection and onsite quick detection.
Owner:广东标允生物科技有限公司 +1

Composition, kit and method for detecting human ethanol metabolism gene polymorphism

The invention provides a composition for detecting ethanol metabolic capacity, and relates to the field of molecular biology detection, in particular to the field of ethanol metabolic capacity detecting. Meanwhile, the invention further provides application of the composition to detection of the ethanol metabolic capacity, a kit comprising the composition, and a method for detecting the ethanol metabolic capacity. By using the composition and the method, the detection time can be greatly shortened.
Owner:SANSURE BIOTECH INC

Chinese medicinal preparation for accelerating alcohol metabolism

Disclosed is a Chinese medicinal preparation for accelerating alcohol metabolism, which comprises the following components (by weight percentage): hovenine seed 25-75%, giant knotweed rhizome 15-35%, cogongrass rhizome 5-25%, and amomum fruit 5-15%.
Owner:SICHUAN UNIV

Monoclonal antibody, enzyme-linked immunosorbent assay method and kit for detecting mequindox and olaquindox metabolites

The invention discloses a specific monoclonal antibody capable of distinguishing mequindox and olaquindox metabolites, and an enzyme-linked immunosorbent assay method and kit for detecting the mequindox and olaquindox metabolites. According to the invention, the monoclonal antibody is secreted by a hybridoma cell strain DMEQ1A3 of which the preservation number is CCTCC N0.C201496. Compared with the prior art, the monoclonal antibody prepared by the invention can distinguish desoxy mequindox and desoxy olaquindox at the same time, and has higher sensitivity and specificity. The ELISA method and the kit, disclosed by the invention, can detect the residue of the mequindox and olaquindox metabolites in meat food at the same time, and have the advantages of high detection efficiency, high sensitivity, high precision, high accuracy and the like.
Owner:HUAZHONG AGRI UNIV

Functional food capable of neutralizing effect of alcoholic drinks and protecting liver and making method of functional food

The invention provides a functional food capable of neutralizing the effect of alcoholic drinks and protecting the liver. The functional food is made from the following raw materials in parts by massof 20-40 parts of a hoveniae semoveniae semen extract, 20-40 parts of a radix puerariae extract, 5-30 parts of a honeysuckle flower extract, 5-30 parts of a green tea extract and 5-20 parts of a licorice root extract. According to the functional food, the hoveniae semoveniae semen extract, the radix puerariae extract, the honeysuckle flower extract, the green tea extract and the licorice root extract are combined in a special compounding ratio, and exert synergistic reaction, so that the functional food having effects of neutralizing the effect of alcoholic drinks and protecting the liver is obtained, is free from toxins and harmless, can improve the ADH activity of liver tissues, can promote ethanol metabolism, can reduce the ethanol concentration in serum, can increase the elimination rate of ethanol metabolism products, can alleviate the damage of tissues and cells, can exert the effects of neutralizing the effect of alcoholic drinks and promoting dispelling the effects of alcohol,can protect the liver, and can reduce the relying and using of medicines, so that toxic and side effects of medicines can be reduced.
Owner:哈福科技(武汉)集团有限公司

Liver-protecting composition and preparation process thereof

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for preventing or treating side effects after drinking. The traditional Chinese medicine composition is mainly prepared from notopterygium root, radix angelicae pubescentis, poria cocos, radix saposhnikoviae, herba schizonepetae, ligusticum wallichii, platycodon grandiflorum, radix bupleuri, radix peucedani, fructus aurantii and liquorice. The traditional Chinese medicine composition disclosed by the invention can relieve oxidative stress injury of alcohol to brain tissues, so that the brain tissues are protected; the ethanol metabolism can be accelerated by increasing the activity of ADH, the activity of SOD can be increased, and the damage to the liver is reduced.
Owner:LUNAN PHARMA GROUP CORPORATION

Method for producing sorbierite by using metal ions to preprocess cells

The invention relates to a method for producing sorbierite by using metal ions to process cells, comprising the following steps of adding metal ions into a system for producing sorbierite by using glucose and fructose as substrates and the zymomonas mobilis which is Gram-negative bacteria to process the cells so as to inhibit the activity of various kinds of enzyme for ethanol metabolism in the zymomonas mobilis, effectively inhibit ethanol generation, and completely convert the glucose and the fructose into sorbierite and gluconic acid. The invention has the advantages that the glucose and the fructose can be completely converted into the sorbierite and the gluconic acid by adding few metal ions into a reaction system; the processing method is simple and avoids the traditional complicated cell processing process; in addition, the products of zinc gluconate and calcium gluconate which are generated by adding some metal ions, such as Zn2+, Ca2+, and the like are objective products so that the burden of a subsequent separating and purifying process is not increased, and the production process of the sorbierite is more feasible.
Owner:EAST CHINA UNIV OF SCI & TECH

Anti-alcohol fruit vinegar paste and preparation method and application thereof

The invention discloses an anti-alcohol fruit vinegar paste and a preparation method and application thereof, and belongs to the technical field of vinegar and preparation thereof. The anti-alcohol fruit vinegar paste with the anti-alcohol and liver protecting effects is prepared in the mode that corn, millet, grapes, radix puerariae, fructus phyllanthi, fructus gardeniae, shaddock peels and the like are mainly adopted as raw materials and subjected to raw material preparation, cooking and liquefaction, alcohol fermentation, acetic acid fermentation, aging and concentration. According to the prepared anti-alcohol fruit vinegar paste, a fruit vinegar brewing process is combined with anti-alcohol effect substances such as the radix puerariae, the fructus phyllanthi, the fructus gardenia andthe shaddock peels, and the anti-alcohol fruit vinegar paste is sour-sweet and tasty, unique in flavor, simple, portable and capable of promoting the ethanol metabolic effect.
Owner:TIANJIN UNIVERSITY OF SCIENCE AND TECHNOLOGY

Composition with disintoxicating and liver-protecting effects and application thereof in food and health-care food

The invention relates to a composition with disintoxicating and liver-protecting effects, which comprises the following raw materials in percentage by mass: 0.15 to 5 percent of crucumin, 0.04 to 1.0 percent of zinc lactate, 10 to 50 percent of glutamine, 10 to 50 percent of alanine and 10 to 50 percent of xylooligosaccharide. It is proved that, by an animal experiment and a human tasting experiment, the composition increases the alcohol dehydrogenase and acetaldehyde dehydrogenase content of a body and rapidly decomposes alcohol, so that the composition has the effects of promoting alcohol metabolism in a liver and reducing the alcohol concentration and active oxygen concentration in a blood; and the composition increases an endurance capacity of a human body to the alcohol, reduces the discomforts such as headache, nausea, vomiting and the like due to the alcohol, and reduces the damages of the alcohol to the liver. The composition can be prepared into food and health-care food withthe disintoxicating and liver-protecting effects, can be used as a disintoxicating product for preventing and improving excessive drinking, and can be used as an adjuvant therapy product for an alcoholic liver, a fatty liver due to the alcohol or non-alcohol and protecting the liver; and the composition has the advantages of safety, non-toxicity and a reliable curative effect.
Owner:SHANDONG MINGREN FURUIDA PHARMA
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