The invention discloses a biological activity bionic calcium phosphate nanometer material which is a nanometer calcium phosphate particle containing at least two elements of silicon, strontium, zinc and magnesium, the mass percent of components shown by an oxide mode is as follows: 40-55 percent of CaO, 38-44 percent of P2O5, 0-0.3 percent of SiO, 0-5.5 percent of SrO, 0-3.5 percent of ZnO, 0-4.5 percent of MgO and 3-8 percent of H2O, wherein the sum of the components is 100 percent, and the contents of at least two materials of SiO2, ZnO, MgO and SrO are not simultaneously 0. The preparation method comprises the steps of adding chain polymer solution containing side chain carboxyl in simulated body fluid, and adding inorganic salt solution containing at least two kinds of ions of silicon, strontium, zinc and magnesium, reacting and aging to analyze the nanometer calcium phosphate particle corporately doped with trace elements, filtering and washing, and drying to obtain the nanometer calcium phosphate particle. The nanometer material can continuously degrade and synchronously release calcium ions, phosphate radical ions and the trace elements in osseous tissues, and is suitable for the repair application of the bone teeth injure of a human body. The invention is simple in process, easy to control the nanometer appearance and size, the trace element composite proportion, and the like.