The invention discloses an MIG welding power supply system based on STM32. The MIG welding power supply system comprises an inversion main circuit and a control circuit. The inversion main circuit comprises an input rectifying filter module, a high-frequency inverting module, a power transformation module and an output rectifying filter module which are sequentially and electrically connected. The control circuit comprises an SMT32 digital control module, a voltage-current detecting module, a fault protecting module, a man-machine interface module and a high-frequency drive module. The man-machine interface module realizes welding parameter giving through a digital pulse encoder. The MIG welding power supply system has the advantages that an STM32 chip is used to control the pulse MIG welding power supply system, system structure is simple, the control function is achieved through software, high anti-interference capability is achieved, and the problems that traditional pulse MIG welding power supply system is complex in structure, large in size, and inaccurate in parameter giving, and the like are solved.