The invention discloses a buckwheat ginseng nutritive health-care soy sauce, which comprises following needed raw materials: buckwheat, peanut cake, semen sesami nigrum, wheat bran and ginseng. The buckwheat ginseng nutritive health-care soy sauce is prepared by a method comprising the following steps of raw material processing, cooking, air drying, vaccinating, starter propagation, fermenting, leach splash lubrication, seasoning, disinfecting and packaging. The product of the invention has thick juice, bright color, moderate salinity, rich nutrition, is natural, fresh and fragrant, integrates the nutritive components of the raw materials into a whole, has the efficacies of tonifying spleen and stomach and regulating vital energy, tonifying spleen and appetizing, promoting digestion and relieving stasis, reinforcing vital energy, benefiting the lung and promoting production of the body fluid and tranquilizing the mind and the like, can treat spleen Qi deficiency, lung Qi deficiency, body fluid consumption and injury and diabetes, has obvious improved function on the diseases, such as heart-blood stagnation, palpitation, insomnia and amnesia and the like, can enhance the immunocompetence of human body, expand blood vessels, regulate blood pressure, increase brain blood and oxygen supply, improve energy metabolism and defer human caducity after being taken for long time.