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Longstamen onion bulb extract as well as preparation method and application thereof

A technology of extract and Allium scallion, applied in the field of Allium scallion extract and its preparation

Active Publication Date: 2009-07-08
炁艾生命科技(深圳)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Whether scallion can be used for the prevention and treatment of metabolic syndrome, especially improving insulin sensitivity, lowering blood sugar and weight loss, has not been reported yet

Method used

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  • Longstamen onion bulb extract as well as preparation method and application thereof
  • Longstamen onion bulb extract as well as preparation method and application thereof
  • Longstamen onion bulb extract as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Embodiment 1, preparation allium scallion extract

[0040] Get the traditional Chinese medicine Allium scallion (Shenzhen Materia Medica Co., Ltd., batch number 070427), and grind it into a coarse powder. Then 200 g of crushed dry bulbs of Allium scallops were soaked overnight with 1000 ml of 55% ethanol aqueous solution by volume, and the leaching solution 1 and filter residue 1 were collected by filtration.

[0041] Then filter residue 1 was mixed with 55% ethanol (ethanol: water = 55: 45, volume ratio) at a mass fraction ratio of 1:5 (filter residue 1: 55% ethanol), refluxed and extracted at 85°C for 2 hours, and suction filtered , collect the first reflux extract 2 and filter residue 2; mix all the obtained filter residue 2 with 55% ethanol, the amount of 55% ethanol is the same as the first time, extract at 85°C for another 2h, and collect the second reflux Extract 3 and filter residue 3, combine leaching solution 1, extract 2 and extract 3, and concentrate the co...

Embodiment 3

[0064] Embodiment 3, the pharmacological effect of Allium scallion extract on metabolic syndrome model mice

[0065] The data in this embodiment are all expressed as Mean±SD, and the data statistics adopt the method of one-way analysis of variance (ANOVA). A P value <0.05 was considered statistically significant.

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Abstract

The invention discloses an allium macrostemon extract and a preparation method and application thereof. The allium macrostemon extract of the invention is prepared by following the method comprising the following steps: allium macrostemon or bulbo of Allium bakeri is soaked in ethanol water with a volume percentage ranging from 45% to 55%, the ethanol water is extracted by reflux, the extracted liquid is collected, thus obtaining the allium macrostemon extract. The allium macrostemon extract can exist in the form of liquid, extractum or drymeal. Tests of pharmacodynamics prove that the alliummacrostemon extract of the invention has the functions of improving energy metabolism of skeletal muscle, strengthening insulin sensitivity, reducing abdominal fat, reducing blood sugar level and promoting lipid metabolism and the like, therefore, the extract can be applied to the prevention and treatment of the increasing metabolic syndromes or to the early prevention of type 2 diabetes.

Description

technical field [0001] The invention relates to a scallion extract, a preparation method and application thereof. Background technique [0002] Metabolic syndrome manifests as central obesity, insulin resistance, impaired glucose tolerance, dyslipidemia, hypertension and other symptoms [Roche HM, Phillips C, Gibney MJ. The metabolic syndrome: the crossroads of diet and genetics. Proc Nutr Soc. 2005 Aug; 64(3):371-7.]. The diagnostic criteria for metabolic syndrome are defined by NCEP ATPIII of the United States, the World Health Organization (WHO) and the International Diabetes Federation (IDF). Although the diagnostic criteria are somewhat controversial, there is a fact that the incidence of metabolic syndrome has been increasing at a high rate in recent years. In the United States, the prevalence of metabolic syndrome is 25% of adults over the age of 20 and 40% of adults over the age of 60. In China, according to the research conducted by The InterASIA Collaborative Gro...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8962A61P3/00A61P3/10A61K125/00
Inventor 谢伟东蔡国平王乃利张雅鸥
Owner 炁艾生命科技(深圳)有限公司
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