37results about How to "Improve population quality" patented technology

The invention relates to the technical field of chemical analysis and detection, and in particular relates to a detection kit based on a tandem mass spectrum non-derivatization method. The detection kit comprises an isotope labeled amino acid standard substance mixture, an isotope labeled acyl carnitine standard substance mixture, an extract liquor and a flow phase. The detection kit based on the tandem mass spectrum non-derivatization method is characterized in that the extract liquor consists of methyl alcohol, water and saturated monocarboxylic acid, wherein the volume ratio of the methyl alcohol to the water to the saturated monocarboxylic acid is 1000: (1-50): (0.01-2). The detection kit based on the tandem mass spectrum non-derivatization method provided by the invention is high in flexibility and accuracy rate, is simple to operate, and has important significance for improving the diagnosis level of metabolic diseases, lowering the burden of society and families and improving the quality of population.

The invention discloses a sexual development abnormality-related gene capture kit and application thereof. The sexual developmental abnormality-related gene capture kit provided by the present invention is to perform target region sequencing on the whole exome or sexual developmental abnormality-related genome (accounting for 1% and 0.01% of the whole genome respectively) of patients with hereditary sexual developmental abnormality Analysis, which captures most of the pathogenic mutation information of the disease, has the advantages of small sample size, low cost, and high throughput, and can detect more samples, which promotes the identification of new pathogenic mutations of genetic abnormalities. Find. The genetic mutation sites related to abnormal sexual development selected in the present invention cover common hotspot mutations and other uncommon mutation points in Chinese. The high-throughput of the kit can comprehensively screen the genes related to abnormal sexual development in the population, which is of great significance for improving the quality of the population and benefiting the society.

The invention provides an in-vitro diagnostic kit of Leber hereditary optic neuropathy (LHON). The in-vitro diagnostic kit comprises SEQIDNO.1-12. The in-vitro diagnostic kit provides a rapid, accurate and cheap genetic level detection means for the clinic diagnosis of the LHON, can realize the prevention and early-stage timely diagnosis of the LHON, can find high risk group, improves the diagnosis rate of the HLON, can effectively realize antenatal genetic counseling and premarital counseling, improves the population quality, and reduces the family and national medical expenditure.

The present invention relates to a kind of compound vitamin-mineral preparation for prenatal taking and belongs to the field of health care medicine. The compound vitamin-mineral preparation consists of carotene, vitamin A, vitamin E, folic acid, vitamin B1, vitamin B2, nicotinamide, vitamin B6, vitamin B12, vitamin D3, vitamin H, pantothenic vitamin, Ca, Mg, I, Fe, Cu and other minerals. It has reasonable recipe, good nourishing health function and no side effect, and is especially suitable for pregnant women to take.

The invention relates to a primer group, a method and a kit for detecting the triploids of a fetus by virtue of plasma free DNS in maternal peripheral blood, wherein the DNA is selected from human No. 21, No. 18 and No. 13 chromosomes, 300 pairs of sequence specific primers are designed with regard to the No. 21, No. 18 and No. 13 chromosomes respectively, each pair of the sequence specific primers comprises a forward primer, a reverse primer and a middle primer, and the gene sequence numbers of the primers are SEQ ID NO: 1-2700. The primer group, the method and the kit disclosed by the invention have the following beneficial effects: the triploids of the fetus are detected by the method disclosed by the invention, the detection is non-invasive detection without a threat on the health of the fetus, diagnosis and detection are high in accuracy and low in expense, flow and data analysis are simple and convenient, and PCR reaction condition requirements are not rigorous; the primer group, the method and the kit are wide in applicability, can be used for promoting the popularization of non-invasive screening for a trisomic syndrome, and are conductive to improving the population quality of China.

The invention discloses a detection method and detection kit for goat LMCD1 gene mononucleotide polymorphism sites. The method comprises the following steps: by using to-be-detected goat genome DNA (deoxyribonucleic acid) of containing LMCD1 gene as a template, carrying out PCR (polymerase chain reaction) amplification on the goat LMCD1 gene, and carrying out SSCP (single strand conformation polymorphism) polymorphism detection. The gene polymorphism sites comprise the following base polymorphisms: the 681st site of the goat LMCD1 gene is A or G; and the 2825th site of the goat LMCD1 gene is C or T. The invention provides a simple quick low-cost high-precision detection method, which can be conveniently applied to screening and detecting of genetic markers closely related to goat growth traits at the DNA level and can be used for assisted selection and molecular breeding of goat.

A non-linear fetal heart rhythm monitor is disclosed. Its monitoring method includes such steps as taking the cardiac sound signals of fetus by ultrasonic Doppler sensor, extracting the envelope of audio signals, transmitting it to A / D interface card PC6360, A / D conversion, and transmitting the converted result to computer aided non-linear analyzing processor which has man-machine interaction interface and the working interface and analyzing software of non-linear kinetic analysis software package.