75 results about "Zedoary oil" patented technology

The invention relates to a Baofukang suppository with an expansion carrier, which is a vaginal suppository prepared by the following components in parts by weight: 60-100 parts of zedoary oil, 60-100 parts of borneol and matrix and 500-2,000 parts of expansion carrier; the surface of the expansion carrier is coated with a drug containing layer formed by at least a part of active ingredients and at least a part of matrix, and the expansion value of the expansion carrier is greater than 1.5. The Baofukang suppository has the benefits that the Baofukang suppository is convenient to use and long in effect time and takes effect fast; the pollution to clothes is avoided; an active drug can be uniformly distributed on a whole vaginal wall and uterine cervix, and permeated into a deep site of mucosa ruffles; surprisingly, the technological effects can still be realized under the conditions that even polyethylene glycol is not used and water is almost not used; the effective rate to mycotic vaginitis is 96.2%; and the effective rate to senile vaginitis is 96.6%.

The hydroxypropyl-beta-cyclodextrin inclusion of Rhizoma zedoariae oil consists of Rhizoma zedoariae oil and hydroxypropyl-beta-cyclodextrin in the ratio of 1 to 1-100. Rhizoma zedoariae oil dissolved in some organic solvent is added into water solution of hydroxypropyl-beta-cyclodextrin via stirring, and the mixture is freeze dried into water soluble inclusion. The included water solution is ultrafiltered, filtered in 0.22 micron porous film and freeze dried to prepare the freeze dried powder for injection. The present invention may be also used for oral taking and external application to result in antiviral and antibacterial effect.

The invention discloses an establishment and evaluation method of a self microemulsion drug administration system public prescription system, which is suitable for multiple drugs. A puerarin, an indomethacin and an oil of zedoary turmeric are selected as the model drug. By adopting an orthogonal design, and multiple-index combined system of solution condition, emulsification speed, emulsification level, fluid level float oil layer and layered precipitation, the composite and dosage of the oil phrase, emulsifier and beeswax in the self microemulsion system are researched, selecting the best prescription composite and proportion. The invention has SMEDDS prescription design by adopting the method of multi-index combined evaluation, ensuring the evaluation index more overall, divided and quantized, with certain demonstration function for evaluating the quality of SMEDDS scientifically, objectively and roundly.

The invention discloses zedoary oil injection and a preparation method thereof. The zedoary oil injection mainly comprises the following components: (1) zedoary oil serving as an active component, (2) 15-hydroxystearic acid macrogol ester (also known as polyethylene glycol-12- hydroxystearic acid ester, and called HS-15 for short) serving as a solubilizing agent, (3) alcohol serving as a cosolvent, and (4) injection for water serving as a solvent. Compared with commercially available injection, the zedoary oil injection has the advantages that the product prepared by adopting a bran-new prescription and technology is in line with the pharmacopoeia criterion for the zedoary oil injection and the safety of clinical medication of the product is also greatly improved.

Extraction of zedoary alcohol is carried out by vacuum split-flowing for zedoary oil, flowing out solid-liquid mixture at some vacuum degree and temperature, collecting the fraction, re-crystallizing for the filtered solid from organic solvent or mixed solvent, and obtaining colorless needle crystal zedoary alcohol. Its advantages include simple process, higher recovery rate and purity.

The invention discloses a healthcare honey pine needle tea powder and a processing method thereof. The tea powder is composed of the following raw materials in parts by weight: 20 to 40 parts of rice wine, 20 to 30 parts of pine needle, 10 to 20 parts of milk powder, 20 to 30 parts of longan pulp, 6 to 10 parts of yak meat, 80 to 100 parts of honey, 10 to 15 parts of haw jam, 2 to 3 parts of pipewort, 1 to 2 parts of fructus viticis, 1 to 3 parts of epimedium, 2 to 3 parts of rabdosia rubescens, 2 to 3 parts of broad bean flower, 2 to 3 parts of pomegranate leaf, 0.1 to 0.2 part of tea polyphenol, 0.1 to 0.2 part of zedoary oil, and 6 to 10 parts of nutrition additive. The prepared healthcare honey pine needle tea powder comprises a pine needle component, so the tea powder has a unique pine needle aroma and the functions of softening the blood vessels, increasing the elasticity of blood vessels, and preventing cardio cerebrovascular diseases. Moreover, yak meat is added to enrich the nutrients and strengthen the immunity, cooperates with other components to generate a synergetic effect, can improve the disease resistant property, and is benefit for human health.

The invention discloses a process for extracting curcumenol by a molecular distillation method. The process comprises the following steps of: adding zedoary oil into a feeding unit; firstly carrying out normal-temperature degassing under vacuum degree, and then opening condensed water and an oil-bath heater; after the temperature is stable, starting scraping-film stirring; then dripping the zedoary oil into a distiller; after the dripping is finished, collecting direct condensation fractions, external condensation fractions, unevaporated residual parts and degassed light components and losing; after the unevaporated residual parts are placed for one day, precipitating a great amount of crystals, using petroleum ether to carry out milliliter pulping, filtering, and drying to obtain white crystal; using alcohol with the mass concentration being 95% to recrystallize the crystal, and obtaining the curcumenol crystal with the gas chromatography GC being larger than 99%. The process disclosed by the invention has the advantages that according to the molecular distillation principle, the zedoary oil is treated by molecular distillation, the liquid part is condensed into liquid on an internal condenser by short-process distillation, then the discharged material is discharged, the zedoary oil can be rapidly separated from the curcumenol, and by combination with the recrystallizing technology, the curcumenol with high purity can be obtained.

The invention belongs to the technical field of medicine, and relates to a preparation method for a zedoary turmeric lactone enantiomer having anti-tumor activity. The structure of the zedoary turmeric lactone enantiomer is represented by a structure (I). The preparation method comprises: adopting new curdione separated from zedoary turmeric oil as a substrate, carrying out a three-step chemical reaction to carry out isomerization on chiral carbon on site 4 to obtain a curdione enantiomer, and carrying out acid catalysis. The test results show that the prepared enantiomer has good anti-tumor activity.

The invention relates to a medicament for treating periodic psychosis. The medicament is prepared by the following method of: decocting 8 to 12 parts of red paeony root and 7.5 to 10.5 parts of raw rhubarb twice, and concentrating filtrate to form extract; crushing 0.5 to 1.5 parts of raw rhubarb, mixing the crushed rhubarb and the extract, and crushing the mixture into fine powder of 80 to 120 meshes; mixing the fine powder, thinner and adhesive uniformly; uniformly spraying 0.02 to 0.03ml of zedoary oil on the granules, and mixing the granules uniformly; and adding a lubricating agent into the granules, and pressing the granules into tablets. The invention also provides a preparation method and application of the medicament for treating the periodic psychosis. The medicament has the advantages that: the compatibility of the whole formula accords with the principle of 'monarch, ministers, assistants and guides'; and proved by years of clinical trials, the medicament has accurate curative effect on the periodic psychosis and a few medicament gouts, has no obvious adverse reaction, is favorable for scale production, and is a safe and effective medicament for treating the periodic psychosis.

The present invention belongs to the field of medicine and medical equipment, relates to medicine eluted rack for preventing and treating re-stenosis inside rack, and is especially curcuma zedoary oil controlled releasing elution rack for preventing and treating re-stenosis inside coronary artery rack. The rack has curcuma zedoary oil as effective medicine component, rack of stainless steel, and composite polybutyl methylacrylate / nanometer silica material as controlled releasing coating. The rack of the present invention has the functions of inhibiting cell growth, inducing apoptosis, resisting inflammation, resisting thrombosis, inhibiting collagen synthesis and resisting proliferation for long time; has excellent tissue compatibility with coronary artery and excellent safety; and can prevent and treat the re-stenosis of the rack operation.